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2021 Journal Article Defining a severe asthma super-responder: findings from a Delphi ProcessUpham, John W., Le Lievre, Chantal, Jackson, David J., Masoli, Matthew, Wechsler, Michael E., Price, David B., Mansur, Adel, Detoraki, Aikaterini, Altraja, Alan, James, Alan, Nanzer-Kelly, Alexandra, Côté, Andréanne, Menzies-Gow, Andrew, Papaioannou, Andriana, Cheffins, Anne-Maree, Bourdin, Arnaud, Mahboub, Bassam, Lipworth, Brian, Celis-Preciado, Carlos Andrés, Torres-Duque, Carlos, Bucca, Caterina, Porsbjerg, Celeste, Ulrik, Charlotte, Corrigan, Chris, Taube, Christian, Farah, Claude, Katelaris, Constance, Langton, David, Ryan, Dermot ... Harrington, Zinta (2021). Defining a severe asthma super-responder: findings from a Delphi Process. Journal of Allergy and Clinical Immunology: In Practice, 9 (11), 3997-4004. doi: 10.1016/j.jaip.2021.06.041 |
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2021 Journal Article Use of direct oral anticoagulants for acute pulmonary embolisms in obesity: a propensity matched multicenter case-control studySamaranayake, Chinthaka B., Keir, Gregory, Slader, Simon A. A., Tseng, T., Tran, Khoa, Anderson, James, McCann, Andrew, McCabe, Colm and Upham, John W. (2021). Use of direct oral anticoagulants for acute pulmonary embolisms in obesity: a propensity matched multicenter case-control study. ERJ Open Research, 7 (3) 00379-2021, 00379-2021. doi: 10.1183/23120541.00379-2021 |
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2021 Journal Article Mepolizumab and oral corticosteroid stewardship: data from the Australian Mepolizumab RegistryThomas, Dennis, Harvey, Erin S., McDonald, Vanessa M., Stevens, Sean, Upham, John W., Katelaris, Constance H., Kritikos, Vicky, Gillman, Andrew, Harrington, John, Hew, Mark, Bardin, Philip, Peters, Matthew, Reynolds, Paul N., Langton, David, Baraket, Melissa, Bowden, Jeffrey J., Bowler, Simon, Chien, Jimmy, Chung, Li Ping, Farah, Claude S., Grainge, Christopher, Jenkins, Christine, Katsoulotos, Gregory P., Lee, Joy, Radhakrishna, Naghmeh, Reddel, Helen K., Rimmer, Janet, Sivakumaran, Pathmanathan, Wark, Peter A.B. and Gibson, Peter G. (2021). Mepolizumab and oral corticosteroid stewardship: data from the Australian Mepolizumab Registry. Journal of Allergy and Clinical Immunology: In Practice, 9 (7), 2715-2724.e5. doi: 10.1016/j.jaip.2021.01.028 |
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2021 Journal Article Add-on azithromycin reduces sputum cytokines in non-eosinophilic asthma: An AMAZES substudyShukla, Shakti D, Taylor, Steven L, Gibson, Peter G, Barker, Daniel, Upham, John W, Yang, Ian A, Reynolds, Paul N, Hodge, Sandra, James, Alan L, Rogers, Geraint B and Simpson, Jodie L (2021). Add-on azithromycin reduces sputum cytokines in non-eosinophilic asthma: An AMAZES substudy. Thorax, 76 (7), 733-736. doi: 10.1136/thoraxjnl-2020-216331 |
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2021 Journal Article Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatmentNiessen, Natalie M., Gibson, Peter G., Baines, Katherine J., Barker, Daniel, Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa, Simpson, Jodie L. and Fricker, Michael (2021). Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment. Allergy, 76 (7) all.14768, 2090-2101. doi: 10.1111/all.14768 |
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2021 Journal Article Duration of amoxicillin-clavulanate for protracted bacterial bronchitis in children (DACS): a multi-centre, double blind, randomised controlled trialRuffles, Tom J. C., Goyal, Vikas, Marchant, Julie M., Masters, I. Brent, Yerkovich, Stephanie, Buntain, Helen, Cook, Anne, Schultz, Andre, Upham, John W., Champion, Anita, Versteegh, Lesley and Chang, Anne B. (2021). Duration of amoxicillin-clavulanate for protracted bacterial bronchitis in children (DACS): a multi-centre, double blind, randomised controlled trial. The Lancet Respiratory Medicine, 9 (10), 1121-1129. doi: 10.1016/s2213-2600(21)00104-1 |
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2021 Journal Article Outcomes of protracted bacterial bronchitis in children: a 5-year prospective cohort studyRuffles, Tom J.C., Marchant, Julie M., Masters, Ian B., Yerkovich, Stephanie T., Wurzel, Danielle F., Gibson, Peter G., Busch, Greta, Baines, Katherine J., Simpson, Jodie L., Smith-Vaughan, Heidi C., Pizzutto, Susan J., Buntain, Helen M., Hodge, Gregory, Hodge, Sandra, Upham, John W. and Chang, Anne B. (2021). Outcomes of protracted bacterial bronchitis in children: a 5-year prospective cohort study. Respirology, 26 (3), 241-248. doi: 10.1111/resp.13950 |
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2021 Journal Article The cost-effectiveness of azithromycin in reducing exacerbations in uncontrolled asthmaO Neill, Ciaran, Gibson, Peter G., Heaney, Liam G., Upham, John W., Yang, Ian A., Reynolds, Paul N., Hodge, Sandra, Jenkins, Christine R., Peters, Matthew, Marks, Guy B., James, Alan L. and Simpson, Jodie L. (2021). The cost-effectiveness of azithromycin in reducing exacerbations in uncontrolled asthma. European Respiratory Journal, 57 (2) 2002436, 2002436. doi: 10.1183/13993003.02436-2020 |
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2021 Journal Article Severe asthma assessment, management and the organisation of care in Australia and New Zealand: expert forum roundtable meetingsMaltby, Steven, McDonald, Vanessa M., Upham, John W., Bowler, Simon D., Chung, Li Ping, Denton, Eve J., Fingleton, James, Garrett, Jeffrey, Grainge, Christopher L., Hew, Mark, James, Alan L., Jenkins, Christine, Katsoulotos, Gregory, King, Gregory G., Langton, David, Marks, Guy B., Menzies‐Gow, Andrew, Niven, Robert M., Peters, Matthew, Reddel, Helen K., Thien, Francis, Thomas, Paul S., Wark, Peter A. B., Yap, Elaine, Gibson, Peter G. and , (2021). Severe asthma assessment, management and the organisation of care in Australia and New Zealand: expert forum roundtable meetings. Internal Medicine Journal, 51 (2) imj.14806, 169-180. doi: 10.1111/imj.14806 |
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2021 Journal Article Thrombolysis for massive pulmonary embolisms in morbid obesity: a multisite case–control studySamaranayake, Chinthaka B., Keir, Gregory, McCabe, Colm, Anderson, James, Tran, Khoa and Upham, John W. (2021). Thrombolysis for massive pulmonary embolisms in morbid obesity: a multisite case–control study. ERJ Open Research, 7 (1) 00762, 1-4. doi: 10.1183/23120541.00762-2020 |
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2020 Journal Article Natural killer cells and host defense against human rhinoviruses is partially dependent on type I IFN signalingvan der Heide, Saskia L., Xi, Yang and Upham, John W. (2020). Natural killer cells and host defense against human rhinoviruses is partially dependent on type I IFN signaling. Frontiers in Cellular and Infection Microbiology, 10 510619, 1-12. doi: 10.3389/fcimb.2020.510619 |
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2020 Journal Article Cumulative dispensing of high oral corticosteroid doses for treating asthma in AustraliaHew, Mark, McDonald, Vanessa M, Bardin, Phil G, Chung, Li Ping, Farah, Claude S, Barnard, Amanda, Cooper, Mark S, Gibson, Peter G and Upham, John W (2020). Cumulative dispensing of high oral corticosteroid doses for treating asthma in Australia. Medical Journal of Australia, 213 (7), 316-320. doi: 10.5694/mja2.50758 |
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2020 Journal Article Plasmacytoid dendritic cells and asthma: a review of current knowledgeXi, Yang and Upham, John W. (2020). Plasmacytoid dendritic cells and asthma: a review of current knowledge. Expert Review of Respiratory Medicine, 14 (11), 1095-`1106. doi: 10.1080/17476348.2020.1803741 |
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2020 Journal Article HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodellingLoh, Zhixuan, Simpson, Jennifer, Ullah, Ashik, Zhang, Vivian, Gan, Wan J., Lynch, Jason P., Werder, Rhiannon B., Sikder, Al Amin, Lane, Katie, Sim, Choon Boon, Porrello, Enzo, Mazzone, Stuart B., Sly, Peter D., Steptoe, Raymond J., Spann, Kirsten M., Sukkar, Maria B., Upham, John W. and Phipps, Simon (2020). HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling. PLoS Pathogens, 16 (7) e1008651, 1-21. doi: 10.1371/journal.ppat.1008651 |
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2020 Journal Article How do biologicals and other novel therapies effect clinically used biomarkers in severe asthma?Upham, John W. and Jurak, Lisa M. (2020). How do biologicals and other novel therapies effect clinically used biomarkers in severe asthma?. Clinical and Experimental Allergy, 50 (9) cea.13694, 994-1006. doi: 10.1111/cea.13694 |
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2020 Journal Article Risks for cold frequency vary by sex: role of asthma, age, TLR7 and leukocyte subsetsMurray, Liisa M., Yerkovich, Stephanie T., Ferreira, Manuel A. and Upham, John W. (2020). Risks for cold frequency vary by sex: role of asthma, age, TLR7 and leukocyte subsets. European Respiratory Journal, 56 (4) 1902453, 1902453. doi: 10.1183/13993003.02453-2019 |
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2020 Journal Article Sphingosine signaling dysfunction in airway cells as a potential contributor to progression from protracted bacterial bronchitis to bronchiectasis in childrenHodge, Sandra, Macowan, Matthew, Liu, Hong, Hamon, Rhys, Chen, Alice C.-H., Marchant, Julie M., Pizzutto, Susan J., Upham, John W. and Chang, Anne B. (2020). Sphingosine signaling dysfunction in airway cells as a potential contributor to progression from protracted bacterial bronchitis to bronchiectasis in children. Pediatric Pulmonology, 55 (6), 1414-1423. doi: 10.1002/ppul.24728 |
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2020 Journal Article Respiratory syncytial virus infection promotes necroptosis and HMGB1 release by airway epithelial cellsSimpson, Jennifer, Loh, Zhixuan, Ullah, Md Ashik, Lynch, Jason P., Werder, Rhiannon B., Collinson, Natasha, Zhang, Vivian, Dondelinger, Yves, Bertrand, Mathieu J M, Everard, Mark L., Blyth, Christopher C., Hartel, Gunter, Van Oosterhout, Antoon J., Gough, Peter J., Bertin, John, Upham, John W., Spann, Kirsten M. and Phipps, Simon (2020). Respiratory syncytial virus infection promotes necroptosis and HMGB1 release by airway epithelial cells. American Journal of Respiratory and Critical Care Medicine, 201 (11), 1358-1371. doi: 10.1164/rccm.201906-1149OC |
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2020 Conference Publication Oral corticosteroid use for asthma in AustraliaHew, M., McDonald, , Bardin, P., Chung, L., Farah, C., Barnard, A., Cooper, M., Gibson, P. and Upham, J. (2020). Oral corticosteroid use for asthma in Australia. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell . |
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2020 Conference Publication Dietary fibre improves antibody responses after influenza vaccine in COPD patients and healthy older peopleSnape, N., Lai, R., Jarnicki, A., Irving, L., Anderson, G., Wood, L. and Upham, J. (2020). Dietary fibre improves antibody responses after influenza vaccine in COPD patients and healthy older people. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell. |
