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2018 Journal Article Optimising treatment for severe asthmaUpham, John W. and Chung, Li Ping (2018). Optimising treatment for severe asthma. Medical Journal of Australia, 209 (2 Suppl), S22-S27. doi: 10.5694/mja18.00175 |
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2018 Journal Article Sputum cytology during late-phase responses to inhalation challenge with different allergensRevez, J. A., Killian, K. J., O'Byrne, P. M., Boulet, L-P., Upham, J. W., Gauvreau, G. M. and Ferreira, M. A. R. (2018). Sputum cytology during late-phase responses to inhalation challenge with different allergens. Allergy, 73 (7), 1470-1478. doi: 10.1111/all.13415 |
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2018 Journal Article PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ productionWerder, Rhiannon B., Lynch, Jason P., Simpson, Jennifer C., Zhang, Vivian, Hodge, Nick H., Poh, Matthew, Forbes-Blom, Elizabeth, Kulis, Christina, Smythe, Mark L., Upham, John W., Spann, Kirsten, Everard, Mark L. and Phipps, Simon (2018). PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-λ production. Science Translational Medicine, 10 (440) eaao0052, eaao0052. doi: 10.1126/scitranslmed.aao0052 |
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2018 Journal Article Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunityWerder, Rhiannon B, Zhang, Vivian, Lynch, Jason P, Snape, Natale, Upham, John W, Spann, Kirsten and Phipps, Simon (2018). Chronic IL-33 expression predisposes to virus-induced asthma exacerbations by increasing type 2 inflammation and dampening antiviral immunity. The Journal of allergy and clinical immunology, 141 (5), 1607-1619.e9. doi: 10.1016/j.jaci.2017.07.051 |
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2018 Journal Article Airway cells from protracted bacterial bronchitis and bronchiectasis share similar gene expression profilesChen, Alice C. -H., Pena, Olga M., Nel, Hendrik J., Yerkovich, Stephanie T., Chang, Anne B., Baines, Katherine J., Gibson, Peter G., Petsky, Helen L., Pizzutto, Susan J., Hodge, Sandra, Masters, Ian B., Buntain, Helen L. and Upham, John W. (2018). Airway cells from protracted bacterial bronchitis and bronchiectasis share similar gene expression profiles. Pediatric Pulmonology, 53 (5), 575-582. doi: 10.1002/ppul.23984 |
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2018 Journal Article Working while unwell: Workplace impairment in people with severe asthmaHiles, S. A., Harvey, E. S., McDonald, V. M., Peters, M., Bardin, P., Reynolds, P. N., Upham, J. W., Baraket, M., Bhikoo, Z., Bowden, J., Brockway, B., Chung, L. P., Cochrane, B., Foxley, G., Garrett, J., Hew, M., Jayaram, L., Jenkins, C., Katelaris, C., Katsoulotos, G., Koh, M. S., Kritikos, V., Lambert, M., Langton, D., Rivero, A. L., Marks, G. B., Middleton, P. G., Nanguzgambo, A., Radhakrishna, N. ... Gibson, P. G. (2018). Working while unwell: Workplace impairment in people with severe asthma. Clinical and Experimental Allergy, 48 (6), 650-662. doi: 10.1111/cea.13153 |
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2018 Conference Publication SEVERE EOSINOPHILIC AASTHMA IN AUSTRALIA: THE AUSTRALIAN MEPOLIZUMAB REGISTRYHarvey, E., Langton, D., Upham, J., Hew, M., Rimmer, J., Chung, L., Katelaris, C., James, A. and Gibson, P. (2018). SEVERE EOSINOPHILIC AASTHMA IN AUSTRALIA: THE AUSTRALIAN MEPOLIZUMAB REGISTRY. HOBOKEN: WILEY. |
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2018 Conference Publication A single bout of moderate-intensity exercise reduces eosinophilic airway inflammation in inactive adults with asthma, while vigorous-intensity exercise has no effectScott, H., Wood, L. and Upham, J. (2018). A single bout of moderate-intensity exercise reduces eosinophilic airway inflammation in inactive adults with asthma, while vigorous-intensity exercise has no effect. ANZSRS/TSANZ Annual Scientific Meeting, Adelaide, Australia, 23-27 March 2018. Richmond, VIC, Australia: Wiley-Blackwell. |
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2018 Conference Publication Differential effects of IL-33 on anti-viral immune responses in asthmatic and healthy individualsUpham, J. W., Jurak, L. and Xi, Y. (2018). Differential effects of IL-33 on anti-viral immune responses in asthmatic and healthy individuals. International Conference of the American Thoracic Society, San Diego, CA, United States, 18-23 May, 2018. New York, NY, United States: American Thoracic Society. |
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2018 Conference Publication IL-33 and rhinovirus effects on IL-33 receptor expression in asthmaUpham, J., Jurak, L. and Xi, Y. (2018). IL-33 and rhinovirus effects on IL-33 receptor expression in asthma. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting, ,, Adelaide, Australia, 23–27 March 2018. Hoboken, NJ United States: Wiley. |
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2018 Conference Publication The impact of TLR7 and TLR8 gene variations on antiviral immunity and asthmaMurray, L. M., Ferreira, M. A. and Upham, J. W. (2018). The impact of TLR7 and TLR8 gene variations on antiviral immunity and asthma. Congress of the European Academy of Allergy and Clinical Immunology (EAACI), Munich, Germany, 26-30 May 2018 . Chichester, West Sussex, United Kingdom: Wiley-Blackwell. |
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2018 Journal Article Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitisChen, Alice C. -H., Tran, Hai B., Xi, Yang, Yerkovich, Stephanie T., Baines, Katherine J., Pizzutto, Susan J., Carroll, Melanie, Robertson, Avril A. B., Cooper, Matthew A., Schroder, Kate, Simpson, Jodie L., Gibson, Peter G., Hodge, Greg, Masters, Ian B., Buntain, Helen M., Petsky, Helen L., Prime, Samantha J., Chang, Anne B., Hodge, Sandra and Upham, John W. (2018). Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis. ERJ Open Research, 4 (1) 00130-2017, 00130-2017. doi: 10.1183/23120541.00130-2017 |
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2018 Conference Publication Protracted bacterial bronchitis (PBB)-long-term outcomes at five years: a cohort studyRuffles, T., Marchant, J., Buntain, H., Mastera,, Upham, J., Yerkovich, S., Gibson, P., Baines, K., Simpson, J., Pizzutto, S., Hodge, G., Hodge, S. and Chang, A. (2018). Protracted bacterial bronchitis (PBB)-long-term outcomes at five years: a cohort study. 55th Annual Scientific Meeting of the Cardiac Society of Aust and NZ Annual Scientific Meeting, Adelaide, Australia, 23-27 March 2018. Richmond, VIC, Australia: Wiley-Blackwell. |
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2017 Journal Article Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansionLynch, Jason P., Werder, Rhiannon B., Loh, Zhixuan, Sikder, Md Al Amin, Curren, Bodie, Zhang, Vivian, Rogers, Matthew J. , Lane, Katie, Simpson, Jennifer, Mazzone, Stuart B., Spann, Kirsten, Hayball, John, Diener, Kerrilyn, Everard, Mark L., Blyth, Christopher C., Forstner, Christian, Dennis, Paul G., Murtaza, Nida, Morrison, Mark, Ó Cuív, Páraic, Zhang, Ping, Haque, Ashraful, Hill, Geoffrey R., Sly, Peter D., Upham, John W. and Phipps, Simon (2017). Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion. The Journal of Experimental Medicine, 215 (2), 537-557. doi: 10.1084/jem.20170298 |
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2017 Journal Article Critical role of plasmacytoid dendritic cells in regulating gene expression and innate immune responses to human rhinovirus-16Xi, Yang, Troy, Niamh M., Anderson, Denise, Pena, Olga M., Lynch, Jason P., Phipps, Simon, Bosco, Anthony and Upham, John W. (2017). Critical role of plasmacytoid dendritic cells in regulating gene expression and innate immune responses to human rhinovirus-16. Frontiers in Immunology, 8 (OCT) 1351, 1351. doi: 10.3389/fimmu.2017.01351 |
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2017 Journal Article Presence of atopy increases the risk of asthma relapseTeoh, Laurel, Mackay, Ian M, Van Asperen, Peter P, Acworth, Jason P, Hurwitz, Mark, Upham, John W, Siew, Weng Hou, Wang, Claire Y T, Sloots, Theo P, Neeman, Teresa and Chang, Anne B (2017). Presence of atopy increases the risk of asthma relapse. Archives of disease in childhood, 103 (4), 346-351. doi: 10.1136/archdischild-2017-312982 |
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2017 Journal Article Utilisation of nicotine replacement therapy within hospital pharmacist initiated smoking-cessation intervention - a pragmatic randomised controlled trialGupta, D., Winckel, K., Burrows, J., Ross, J. and Upham, J. W. (2017). Utilisation of nicotine replacement therapy within hospital pharmacist initiated smoking-cessation intervention - a pragmatic randomised controlled trial. Journal of Smoking Cessation, 12 (1), 1-10. doi: 10.1017/jsc.2015.14 |
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2017 Journal Article Cytokine responses to two common respiratory pathogens in children are dependent on interleukin-1βChen, Alice C.-H., Xi, Yang, Carroll, Melanie, Petsky, Helen L., Gardiner, Samantha J., Pizzutto, Susan J., Yerkovich, Stephanie T., Baines, Katherine J., Gibson, Peter G., Hodge, Sandra, Masters, Ian B., Buntain, Helen M., Chang, Anne B. and Upham, John W. (2017). Cytokine responses to two common respiratory pathogens in children are dependent on interleukin-1β. ERJ Open Research, 3 (4) 00025-2017, 00025-2017. doi: 10.1183/23120541.00025-2017 |
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2017 Conference Publication Sputum IL-1 beta is reduced with Azithromycin add-on therapy in patients with poorly controlled asthmaSimpson, Jodie, Powell, Heather, Pabreja, Kavita, Yang, Ian, Upham, John, Reynolds, Paul, Hodge, Sandra, James, Alan, Jenkins, Christine, Peters, Matthew, Marks, Guy, Gibson, Peter and Baraket, Melissa (2017). Sputum IL-1 beta is reduced with Azithromycin add-on therapy in patients with poorly controlled asthma. European-Respiratory-Society (ERS) International Congress, Milan Italy, Sep 09-13, 2017. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. doi: 10.1183/1393003.congress-2017.PA4029 |
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2017 Journal Article Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trialGibson, Peter G., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa, Powell, Heather, Taylor, Steven L., Leong, Lex E. X., Rogers, Geraint B. and Simpson, Jodie L. (2017). Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. The Lancet, 390 (10095), 659-668. doi: 10.1016/S0140-6736(17)31281-3 |
