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2017

Journal Article

Critical role of plasmacytoid dendritic cells in regulating gene expression and innate immune responses to human rhinovirus-16

Xi, Yang, Troy, Niamh M., Anderson, Denise, Pena, Olga M., Lynch, Jason P., Phipps, Simon, Bosco, Anthony and Upham, John W. (2017). Critical role of plasmacytoid dendritic cells in regulating gene expression and innate immune responses to human rhinovirus-16. Frontiers in Immunology, 8 (OCT) 1351, 1351. doi: 10.3389/fimmu.2017.01351

Critical role of plasmacytoid dendritic cells in regulating gene expression and innate immune responses to human rhinovirus-16

2017

Journal Article

Presence of atopy increases the risk of asthma relapse

Teoh, Laurel, Mackay, Ian M, Van Asperen, Peter P, Acworth, Jason P, Hurwitz, Mark, Upham, John W, Siew, Weng Hou, Wang, Claire Y T, Sloots, Theo P, Neeman, Teresa and Chang, Anne B (2017). Presence of atopy increases the risk of asthma relapse. Archives of disease in childhood, 103 (4), 346-351. doi: 10.1136/archdischild-2017-312982

Presence of atopy increases the risk of asthma relapse

2017

Journal Article

Utilisation of nicotine replacement therapy within hospital pharmacist initiated smoking-cessation intervention - a pragmatic randomised controlled trial

Gupta, D., Winckel, K., Burrows, J., Ross, J. and Upham, J. W. (2017). Utilisation of nicotine replacement therapy within hospital pharmacist initiated smoking-cessation intervention - a pragmatic randomised controlled trial. Journal of Smoking Cessation, 12 (1), 1-10. doi: 10.1017/jsc.2015.14

Utilisation of nicotine replacement therapy within hospital pharmacist initiated smoking-cessation intervention - a pragmatic randomised controlled trial

2017

Journal Article

Cytokine responses to two common respiratory pathogens in children are dependent on interleukin-1β

Chen, Alice C.-H., Xi, Yang, Carroll, Melanie, Petsky, Helen L., Gardiner, Samantha J., Pizzutto, Susan J., Yerkovich, Stephanie T., Baines, Katherine J., Gibson, Peter G., Hodge, Sandra, Masters, Ian B., Buntain, Helen M., Chang, Anne B. and Upham, John W. (2017). Cytokine responses to two common respiratory pathogens in children are dependent on interleukin-1β. ERJ Open Research, 3 (4) 00025-2017, 00025-2017. doi: 10.1183/23120541.00025-2017

Cytokine responses to two common respiratory pathogens in children are dependent on interleukin-1β

2017

Conference Publication

Sputum IL-1 beta is reduced with Azithromycin add-on therapy in patients with poorly controlled asthma

Simpson, Jodie, Powell, Heather, Pabreja, Kavita, Yang, Ian, Upham, John, Reynolds, Paul, Hodge, Sandra, James, Alan, Jenkins, Christine, Peters, Matthew, Marks, Guy, Gibson, Peter and Baraket, Melissa (2017). Sputum IL-1 beta is reduced with Azithromycin add-on therapy in patients with poorly controlled asthma. European-Respiratory-Society (ERS) International Congress, Milan Italy, Sep 09-13, 2017. SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. doi: 10.1183/1393003.congress-2017.PA4029

Sputum IL-1 beta is reduced with Azithromycin add-on therapy in patients with poorly controlled asthma

2017

Journal Article

Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial

Gibson, Peter G., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa, Powell, Heather, Taylor, Steven L., Leong, Lex E. X., Rogers, Geraint B. and Simpson, Jodie L. (2017). Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. The Lancet, 390 (10095), 659-668. doi: 10.1016/S0140-6736(17)31281-3

Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial

2017

Journal Article

Management of hypoxaemic respiratory failure in a Respiratory High-dependency Unit

Hukins, Craig, Wong, Mimi, Murphy, Michelle and Upham, John (2017). Management of hypoxaemic respiratory failure in a Respiratory High-dependency Unit. Internal Medicine Journal, 47 (7), 784-792. doi: 10.1111/imj.13403

Management of hypoxaemic respiratory failure in a Respiratory High-dependency Unit

2017

Journal Article

Bronchiectasis in children: current concepts in immunology and microbiology

Pizzutto, Susan J., Hare, Kim M. and Upham, John W. (2017). Bronchiectasis in children: current concepts in immunology and microbiology. Frontiers in Pediatrics, 5 123, 123. doi: 10.3389/fped.2017.00123

Bronchiectasis in children: current concepts in immunology and microbiology

2017

Journal Article

Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology

Taylor, Steven L., Leong, Lex E. X., Choo, Jocelyn M., Wesselingh, Steve, Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Baraket, Melissa, Marks, Guy B., Gibson, Peter G., Simpson, Jodie L. and Rogers, Geraint B. (2017). Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology. Journal of Allergy and Clinical Immunology, 141 (1), 94-103.e15. doi: 10.1016/j.jaci.2017.03.044

Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology

2017

Journal Article

Response

Wurzel, Danielle F., Marchant, Julie M., Yerkovich, Stephanie T., Upham, John W. and Chang, Anne B. (2017). Response. Chest, 151 (4), 940-941. doi: 10.1016/j.chest.2016.12.030

Response

2017

Journal Article

Can biomarkers help us hit targets in difficult-to-treat asthma?

Fricker, Michael, Heaney, Liam G. and Upham, John W. (2017). Can biomarkers help us hit targets in difficult-to-treat asthma?. Respirology, 22 (3), 430-442. doi: 10.1111/resp.13014

Can biomarkers help us hit targets in difficult-to-treat asthma?

2017

Journal Article

Dendritic cells in human lung disease: recent advances

Upham, John W. and Xi, Yang (2017). Dendritic cells in human lung disease: recent advances. Chest, 151 (3), 668-673. doi: 10.1016/j.chest.2016.09.030

Dendritic cells in human lung disease: recent advances

2017

Conference Publication

An Analysis of the Effect of Azithromycin in Persistent Asthma, Based On Pre-Specified Asthma Phenotypes

Powell, Heather, Simpson, Jodie L., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Baraket, Melissa, Marks, Guy B. and Gibson, Peter G. (2017). An Analysis of the Effect of Azithromycin in Persistent Asthma, Based On Pre-Specified Asthma Phenotypes. HOBOKEN: WILEY.

An Analysis of the Effect of Azithromycin in Persistent Asthma, Based On Pre-Specified Asthma Phenotypes

2017

Journal Article

RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma

Arikkatt, Jaisy, Ullah, Md Ashik, Short, Kirsty Renfree, Zhang, Vivian, Gan, Wan Jun, Loh, Zhixuan, Werder, Rhiannon B., Simpson, Jennifer, Sly, Peter D., Mazzone, Stuart B., Spann, Kirsten M., Ferreira, Manuel A R., Upham, John W., Sukkar, Maria B. and Phipps, Simon (2017). RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma. eLife, 6 e21199. doi: 10.7554/eLife.21199

RAGE deficiency predisposes mice to virus-induced paucigranulocytic asthma

2017

Conference Publication

IL-33 augments rhinovirus-induced type 2 immune responses in asthma via selective upregulation of one chain of the IL-33 receptor

Upham, John, Jurak, Lisa and Xi, Yang (2017). IL-33 augments rhinovirus-induced type 2 immune responses in asthma via selective upregulation of one chain of the IL-33 receptor. ERS International Congress 2017, Milan, Italy, 9-13 September 2017. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/1393003.congress-2017.pa567

IL-33 augments rhinovirus-induced type 2 immune responses in asthma via selective upregulation of one chain of the IL-33 receptor

2017

Conference Publication

Determinants Of Rhinovirus And Nucleic Acid Induced Cytokine Production In A Large Group Of Healthy And Asthmatic Individuals

Upham, J. W., Murray, L., Xi, Y., Revez, J. and Ferreira, M. (2017). Determinants Of Rhinovirus And Nucleic Acid Induced Cytokine Production In A Large Group Of Healthy And Asthmatic Individuals. International Conference of the American-Thoracic-Society (ATS), Washington Afghanistan, 19-24 May 2017. New York, NY United States: American Thoracic Society.

Determinants Of Rhinovirus And Nucleic Acid Induced Cytokine Production In A Large Group Of Healthy And Asthmatic Individuals

2017

Conference Publication

Azithromycin Reduces Exacerbations In Adults With Persistent Symptomatic Eosinophilic Asthma

Gibson, P. G., Yang, I. A., Upham, J. W., Reynolds, P. N., Hodge, S., James, A. L., Jenkins, C., Peters, M., Marks, G. B., Baraket, M., Simpson, J. L. and Powell, H. (2017). Azithromycin Reduces Exacerbations In Adults With Persistent Symptomatic Eosinophilic Asthma. International Conference of the American-Thoracic-Society (ATS), Washington Dc, May 19-24, 2017. NEW YORK: AMER THORACIC SOC.

Azithromycin Reduces Exacerbations In Adults With Persistent Symptomatic Eosinophilic Asthma

2017

Conference Publication

Azithromycin Reduces Exacerbations in Adults with Persistent Symptomatic Eosinophilic Asthma

Gibson, Peter G., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa, Powell, Heather and Simpson, Jodie L. (2017). Azithromycin Reduces Exacerbations in Adults with Persistent Symptomatic Eosinophilic Asthma. HOBOKEN: WILEY.

Azithromycin Reduces Exacerbations in Adults with Persistent Symptomatic Eosinophilic Asthma

2017

Conference Publication

Determinants of Rhinovirus and Nucleic Acid Induced Cytokine Production in a Large Cohort

Murray, Liisa, Xi, Yang, Revez, Joana A., Ferreira, Manuel A. and Upham, John W. (2017). Determinants of Rhinovirus and Nucleic Acid Induced Cytokine Production in a Large Cohort. The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting, Canberra, Australia, 24–28 March 2017. Richmond, VIC Australia: Wiley.

Determinants of Rhinovirus and Nucleic Acid Induced Cytokine Production in a Large Cohort

2016

Journal Article

Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2015: the Influenza Complications Alert Network

Cheng, Allen C., Holmes, Mark, Dwyer, Dominic E., Irving, Louis B., Korman, Tony M., Senenayake, Sanjaya, Macartney, Kristine K., Blyth, Christopher C., Brown, Simon, Waterer, Grant, Hewer, Robert, Friedman, N Deborah, Wark, Peter A., Simpson, Graham, Upham, John, Bowler, Simon D., Lessing, Albert, Kotsimbos, Tom and Kelly, Paul M. (2016). Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2015: the Influenza Complications Alert Network. Communicable Diseases Intelligence Quarterly Report, 40 (4), E521-E526. doi: 10.33321/cdi.2016.40.59

Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2015: the Influenza Complications Alert Network