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2016

Conference Publication

Clinical Effectiveness Of Omalizumab In Severe Allergic Asthma Above The Recommended Dosing Range: The Australian Xolair Registry

Hew, M., Gillman, A., Sutherland, M., Wark, P., Bowden, J., McDonald, V., Guo, M., Reddel, H., Jenkins, C., Marks, G., Upham, J., Thien, F., Rimmer, J., Katsoulotos, G. P., Cook, M., Yang, I., Katelaris, C., Bowler, S., Langton, D., Gibson, P. G., Robinson, P. D., Wright, C., Bint, M., Yozghatlian, V., Burgess, S., Sivakumaran, P., Jaffe, A., Yan, K., Peters, M. ... Aminazad, A. (2016). Clinical Effectiveness Of Omalizumab In Severe Allergic Asthma Above The Recommended Dosing Range: The Australian Xolair Registry. International Conference of the American-Thoracic-Society (ATS), San Francisco Ca, May 13-18, 2016. NEW YORK: AMER THORACIC SOC.

Clinical Effectiveness Of Omalizumab In Severe Allergic Asthma Above The Recommended Dosing Range: The Australian Xolair Registry

2016

Conference Publication

Il-33 Augments Rhinovirus-Induced Type 2 Immune Responses in Subjects with Asthma, But Not in Healthy Individuals

Upham, J., Landgraf, M., Xi, Y. and Carroll, M. (2016). Il-33 Augments Rhinovirus-Induced Type 2 Immune Responses in Subjects with Asthma, But Not in Healthy Individuals. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA Australia, 1-6 April 2016. HOBOKEN: WILEY-BLACKWELL.

Il-33 Augments Rhinovirus-Induced Type 2 Immune Responses in Subjects with Asthma, But Not in Healthy Individuals

2016

Conference Publication

Critical role of pDC in regulating gene expression and innate immune responses to human rhinovirus

Xi, Y., Bosco, A. and Upham, J. W. (2016). Critical role of pDC in regulating gene expression and innate immune responses to human rhinovirus. International Congress of Immunology (ICI), Melbourne Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Critical role of pDC in regulating gene expression and innate immune responses to human rhinovirus

2016

Conference Publication

Critical Role of pDC in regulating gene expression and innate immune responses to human rhinovirus

Xi, Yang , Anthony, Bosco and Upham, John (2016). Critical Role of pDC in regulating gene expression and innate immune responses to human rhinovirus. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21-26 August 2016.

Critical Role of pDC in regulating gene expression and innate immune responses to human rhinovirus

2016

Conference Publication

LSC Abstract - Punching above their weight: Plasmacytoid dendritic cells play a critical role in regulating rhinovirus induced gene expression pathways

Upham, John, Xi, Camilla, Pena, Olga and Bosco, Anthony (2016). LSC Abstract - Punching above their weight: Plasmacytoid dendritic cells play a critical role in regulating rhinovirus induced gene expression pathways. ERS International Congress 2016, London, United Kingdom, 3-7 September, 2016. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2016.PP236

LSC Abstract - Punching above their weight: Plasmacytoid dendritic cells play a critical role in regulating rhinovirus induced gene expression pathways

2016

Conference Publication

Uncoupling of the Pdc-Treg Crosstalk During Early-Life Pneumovirus Infection Underlies Long-Lived Treg Dysfunction and Asthma Development

Lynch, J., Rogers, M., Lane, K., Werder, R., Loh, Z., Diener, K., Hayball, J., Hill, G., Haque, A., Spann, K., Mazzone, S., Upham, J. and Phipps, S. (2016). Uncoupling of the Pdc-Treg Crosstalk During Early-Life Pneumovirus Infection Underlies Long-Lived Treg Dysfunction and Asthma Development. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/resp.12755_3

Uncoupling of the Pdc-Treg Crosstalk During Early-Life Pneumovirus Infection Underlies Long-Lived Treg Dysfunction and Asthma Development

2016

Conference Publication

Prostaglandin D2 contributes to severity of pneumoviral bronchiolitis

Werder, R., Hodge, N., Lynch, J., Simpson, J., Zhang, V, Forbes-Blom, E., Upham, J., Spann, K., Everard, M. and Phipps, S. (2016). Prostaglandin D2 contributes to severity of pneumoviral bronchiolitis. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA Australia, 1-6 April 2016. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.

Prostaglandin D2 contributes to severity of pneumoviral bronchiolitis

2016

Conference Publication

Alveolar macrophage in protracted bacterial bronchitis

Chen, Alice, Pena, Olga, Nel, Hanno, Pizzuto, Susan, Petsky, Helen, Gardiner, Samantha, Yerkovich, Stephanie, Baines, Katie, Gibson, Peter, Hodge, Greg, Hodge, Sandra, Buntain, Helen, Chang, Anne and Upham, John (2016). Alveolar macrophage in protracted bacterial bronchitis. ERS International Congress 2016, London, United Kingdom, 2016. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2016.PA3977

Alveolar macrophage in protracted bacterial bronchitis

2016

Journal Article

Blood cytotoxic/inflammatory mediators in non-eosinophilic asthma

Hodge, S., Hodge, G., Simpson, J. L., Yang, I. A., Upham, J., James, A., Gibson, P. G. and Reynolds, P. N. (2016). Blood cytotoxic/inflammatory mediators in non-eosinophilic asthma. Clinical and Experimental Allergy, 46 (1), 60-70. doi: 10.1111/cea.12634

Blood cytotoxic/inflammatory mediators in non-eosinophilic asthma

2016

Conference Publication

Plasmacytoid Dendritic Cells Play a Critical Role in Regulating Rhinovirus Induced Gene Expression Pathways

Upham, J., Xi, Y., Pena, O. and Bosco, A. (2016). Plasmacytoid Dendritic Cells Play a Critical Role in Regulating Rhinovirus Induced Gene Expression Pathways. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA Australia, 1-6 April 2016. HOBOKEN: European Respiratory Society. doi: 10.1183/13993003.congress-2016.pp236

Plasmacytoid Dendritic Cells Play a Critical Role in Regulating Rhinovirus Induced Gene Expression Pathways

2016

Conference Publication

Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening Type I and III interferon production

Werder, R. B., Lynch, J., Simpson, J., Loh, Z., Zhang, V., Spann, K., Sly, P., Mazzone, S., Upham, J. and Phipps, S. (2016). Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening Type I and III interferon production. 4th Annual Meeting of The International Cytokine and Interferon Society (ICIS), San Francisco, CA, United States, October 16 - 19 2016. London, United Kingdom: Academic Press.

Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening Type I and III interferon production

2016

Conference Publication

The Lung Microbiota In Stable Adult Asthma Differs According To Inflammatory Phenotype, Sex, And Atopy

Rogers, G. B., Leong, L. E., Gibson, P. G., Yang, I. A., Hodge, S. J., Reynolds, P. N., James, A. L., Upham, J. W., Jenkins, C., Peters, M., Baraket, M. and Simpsons, J. L. (2016). The Lung Microbiota In Stable Adult Asthma Differs According To Inflammatory Phenotype, Sex, And Atopy. International Conference of the American-Thoracic-Society (ATS), San Francisco, Ca, United States, May 13-18, 2016. NEW YORK: AMER THORACIC SOC.

The Lung Microbiota In Stable Adult Asthma Differs According To Inflammatory Phenotype, Sex, And Atopy

2015

Journal Article

Rhinovirus stimulated IFN-α production: how important are plasmacytoid DCs, monocytes and endosomal pH?

Xi, Yang, Finlayson, Arvid, White, Oliva J., Carroll, Melanie L. and Upham, John W. (2015). Rhinovirus stimulated IFN-α production: how important are plasmacytoid DCs, monocytes and endosomal pH?. Clinical and Translational Immunology, 4 (10) e46, e46. doi: 10.1038/cti.2015.27

Rhinovirus stimulated IFN-α production: how important are plasmacytoid DCs, monocytes and endosomal pH?

2015

Journal Article

Influenza epidemiology in adults admitted to sentinel Australian hospitals in 2014: the Influenza Complications Alert Network (FluCAN)

Cheng, Allen C., Holmes, Mark, Senenayake, Sanjaya, Dwyer, Dominic E., Hewagama, Saliya, Korman, Tony, Irving, Louis, Brown, Simon, Waterer, Grant, Hunter, Cameron, Friedman, N. Deborah, Wark, Peter, Simpson, Graham, Upman, John, Bowler, Simon, Macartney, Kristine, Blyth, Christopher, Kotsimbos, Tom and Kelly, Paul (2015). Influenza epidemiology in adults admitted to sentinel Australian hospitals in 2014: the Influenza Complications Alert Network (FluCAN). Communicable Diseases Intelligence Quarterly Report, 39 (3), E355-E360.

Influenza epidemiology in adults admitted to sentinel Australian hospitals in 2014: the Influenza Complications Alert Network (FluCAN)

2015

Journal Article

Increased peripheral blood pro-inflammatory/cytotoxic lymphocytes in children with bronchiectasis

Hodge, G., Upham, J. W., Chang, A. B., Baines, K. J., Yerkovich, S. T., Pizzutto, S. J. and Hodge, S. (2015). Increased peripheral blood pro-inflammatory/cytotoxic lymphocytes in children with bronchiectasis. PLoS One, 10 (8) e0133695, e0133695. doi: 10.1371/journal.pone.0133695

Increased peripheral blood pro-inflammatory/cytotoxic lymphocytes in children with bronchiectasis

2015

Journal Article

High pulmonary levels of IL-6 and IL-1β in children with chronic suppurative lung disease are associated with low systemic IFN-γ production in response to non-typeable Haemophilus influenzae

Pizzutto, Susan J., Upham, John W., Yerkovich, Stephanie T. and Chang, Anne B. (2015). High pulmonary levels of IL-6 and IL-1β in children with chronic suppurative lung disease are associated with low systemic IFN-γ production in response to non-typeable Haemophilus influenzae. PLoS One, 10 (6) e0129517, e0129517-e0129517. doi: 10.1371/journal.pone.0129517

High pulmonary levels of IL-6 and IL-1β in children with chronic suppurative lung disease are associated with low systemic IFN-γ production in response to non-typeable Haemophilus influenzae

2015

Journal Article

Glycopyrronium once-daily significantly improves lung function and health status when combined with salmeterol/fluticasone in patients with COPD: The GLISTEN study - a randomised controlled trial

Frith, Peter A., Thompson, Philip J., Ratnavadivel, Rajeev, Chang, Catherina L., Bremner, Peter, Day, Peter, Frenzel, Christina, Kurstjens, Nicol, Waddell, Ainslie, Daniel, Alexander, Khoussousi, Alireza, Springfield, Andrew, Veale, Andrew, Graham, Anthony Neil, Gallagher, Brad, Pande, Braj Raj, O'Kane, Brendan, Jones, Christopher, Baldi, Claudio, Helm, Colin, O'Dochartaigh, Conor, Chambers, Daniel, Quinn, Dean, Yull, Derek, Karthigesu, Dhanalakshi, Then, Edward, Graham, Frank, Faigenbaum, Fred, Geddam, Geetha ... Hess, Zofia (2015). Glycopyrronium once-daily significantly improves lung function and health status when combined with salmeterol/fluticasone in patients with COPD: The GLISTEN study - a randomised controlled trial. Thorax, 70 (6), 519-527. doi: 10.1136/thoraxjnl-2014-206670

Glycopyrronium once-daily significantly improves lung function and health status when combined with salmeterol/fluticasone in patients with COPD: The GLISTEN study - a randomised controlled trial

2015

Conference Publication

HIGH PULMONARY EXPRESSION OF IL-6 AND IL-1BETA IN CHILDREN WITH SUPPURATIVE LUNG DISEASE IS ASSOCIATED WITH IMPAIRED RECALL RESPONSES TO H. INFLUENZAE

Pizzutto, S. J., Upham, J. W., Yerkovich, S. T. and Chang, A. B. (2015). HIGH PULMONARY EXPRESSION OF IL-6 AND IL-1BETA IN CHILDREN WITH SUPPURATIVE LUNG DISEASE IS ASSOCIATED WITH IMPAIRED RECALL RESPONSES TO H. INFLUENZAE. HOBOKEN: WILEY-BLACKWELL.

HIGH PULMONARY EXPRESSION OF IL-6 AND IL-1BETA IN CHILDREN WITH SUPPURATIVE LUNG DISEASE IS ASSOCIATED WITH IMPAIRED RECALL RESPONSES TO H. INFLUENZAE

2015

Journal Article

Acute exercise is associated with reduced exhaled nitric oxide in physically inactive adults with asthma

Scott, Hayley A., Latham, Jennifer R., Callister, Robin, Pretto, Jeffrey J., Baines, Katherine, Saltos, Nick, Upham, John W. and Wood, Lisa G. (2015). Acute exercise is associated with reduced exhaled nitric oxide in physically inactive adults with asthma. Annals of Allergy, Asthma and Immunology, 114 (6), 470-479. doi: 10.1016/j.anai.2015.04.002

Acute exercise is associated with reduced exhaled nitric oxide in physically inactive adults with asthma

2015

Journal Article

IgE+ B cells are scarce, but allergen-specific B cells with a memory phenotype circulate in patients with allergic rhinitis

Wong, K.J, Timbrell, Victoria L., Xi, Y, Upham, J.W, Collins, A.M and Davies, J.M (2015). IgE+ B cells are scarce, but allergen-specific B cells with a memory phenotype circulate in patients with allergic rhinitis. Allergy: European Journal of Allergy and Clinical Immunology, 70 (4), 420-428. doi: 10.1111/all.12563

IgE+ B cells are scarce, but allergen-specific B cells with a memory phenotype circulate in patients with allergic rhinitis