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2016

Journal Article

Reduced antiviral interferon production in poorly controlled asthma is associated with neutrophilic inflammation and high-dose inhaled corticosteroids

Simpson, Jodie L., Carroll, Melanie, Yang, Ian A., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Gibson, Peter G. and Upham, John W. (2016). Reduced antiviral interferon production in poorly controlled asthma is associated with neutrophilic inflammation and high-dose inhaled corticosteroids. Chest, 149 (3), 704-713. doi: 10.1016/j.chest.2015.12.018

Reduced antiviral interferon production in poorly controlled asthma is associated with neutrophilic inflammation and high-dose inhaled corticosteroids

2016

Journal Article

Airway dysbiosis: Haemophilus influenzae and Tropheryma in poorly controlled asthma

Simpson, Jodie L., Daly, Joshua, Baines, Katherine J., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Hugenholtz, Philip, Willner, Dana and Gibson, Peter G. (2016). Airway dysbiosis: Haemophilus influenzae and Tropheryma in poorly controlled asthma. European Respiratory Journal, 47 (3), 792-800. doi: 10.1183/13993003.00405-2015

Airway dysbiosis: Haemophilus influenzae and Tropheryma in poorly controlled asthma

2016

Journal Article

Protracted bacterial bronchitis: the last decade and the road ahead

Chang, Anne B., Upham, John W., Masters, I. Brent, Redding, Gregory R., Gibson, Peter G., Marchant, Julie M. and Grimwood, Keith (2016). Protracted bacterial bronchitis: the last decade and the road ahead. Pediatric Pulmonology, 51 (3), 225-242. doi: 10.1002/ppul.23351

Protracted bacterial bronchitis: the last decade and the road ahead

2016

Journal Article

Is alveolar macrophage phagocytic dysfunction in children with protracted bacterial bronchitis a forerunner to bronchiectasis?

Hodge, Sandra, Upham, John W., Pizzutto, Susan, Petsky, Helen L., Yerkovich, Stephanie, Baines, Katherine J., Gibson, Peter, Simpson, Jodie L., Buntain, Helen, Chen, Alice C. H., Hodge, Greg and Chang, Anne B. (2016). Is alveolar macrophage phagocytic dysfunction in children with protracted bacterial bronchitis a forerunner to bronchiectasis?. Chest, 149 (2), 508-515. doi: 10.1016/j.chest.2015.10.066

Is alveolar macrophage phagocytic dysfunction in children with protracted bacterial bronchitis a forerunner to bronchiectasis?

2016

Journal Article

Inhaled non-steroid anti-inflammatories for children and adults with bronchiectasis(Review)

Pizzutto, Susan J., Upham, John W., Yerkovich, Stephanie T. and Chang, Anne B. (2016). Inhaled non-steroid anti-inflammatories for children and adults with bronchiectasis(Review). Cochrane Database of Systematic Reviews, 2016 (1) CD007525. doi: 10.1002/14651858.CD007525.pub3

Inhaled non-steroid anti-inflammatories for children and adults with bronchiectasis(Review)

2016

Conference Publication

LSC Abstract - Punching above their weight: Plasmacytoid dendritic cells play a critical role in regulating rhinovirus induced gene expression pathways

Upham, John, Xi, Camilla, Pena, Olga and Bosco, Anthony (2016). LSC Abstract - Punching above their weight: Plasmacytoid dendritic cells play a critical role in regulating rhinovirus induced gene expression pathways. ERS International Congress 2016, London, United Kingdom, 3-7 September, 2016. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2016.PP236

LSC Abstract - Punching above their weight: Plasmacytoid dendritic cells play a critical role in regulating rhinovirus induced gene expression pathways

2016

Conference Publication

Il-33 Augments Rhinovirus-Induced Type 2 Immune Responses in Subjects with Asthma, But Not in Healthy Individuals

Upham, J., Landgraf, M., Xi, Y. and Carroll, M. (2016). Il-33 Augments Rhinovirus-Induced Type 2 Immune Responses in Subjects with Asthma, But Not in Healthy Individuals. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA Australia, 1-6 April 2016. HOBOKEN: WILEY-BLACKWELL.

Il-33 Augments Rhinovirus-Induced Type 2 Immune Responses in Subjects with Asthma, But Not in Healthy Individuals

2016

Conference Publication

Critical role of pDC in regulating gene expression and innate immune responses to human rhinovirus

Xi, Y., Bosco, A. and Upham, J. W. (2016). Critical role of pDC in regulating gene expression and innate immune responses to human rhinovirus. International Congress of Immunology (ICI), Melbourne Australia, 21-26 August 2016. Weinheim, Germany: Wiley.

Critical role of pDC in regulating gene expression and innate immune responses to human rhinovirus

2016

Conference Publication

Critical Role of pDC in regulating gene expression and innate immune responses to human rhinovirus

Xi, Yang , Anthony, Bosco and Upham, John (2016). Critical Role of pDC in regulating gene expression and innate immune responses to human rhinovirus. ICI 2016 International Congress of Immunology, Melbourne, Australia, 21-26 August 2016.

Critical Role of pDC in regulating gene expression and innate immune responses to human rhinovirus

2016

Conference Publication

Uncoupling of the Pdc-Treg Crosstalk During Early-Life Pneumovirus Infection Underlies Long-Lived Treg Dysfunction and Asthma Development

Lynch, J., Rogers, M., Lane, K., Werder, R., Loh, Z., Diener, K., Hayball, J., Hill, G., Haque, A., Spann, K., Mazzone, S., Upham, J. and Phipps, S. (2016). Uncoupling of the Pdc-Treg Crosstalk During Early-Life Pneumovirus Infection Underlies Long-Lived Treg Dysfunction and Asthma Development. International Congress of Immunology (ICI), Melbourne Australia, Aug 21-26, 2016. HOBOKEN: WILEY-BLACKWELL. doi: 10.1111/resp.12755_3

Uncoupling of the Pdc-Treg Crosstalk During Early-Life Pneumovirus Infection Underlies Long-Lived Treg Dysfunction and Asthma Development

2016

Conference Publication

Alveolar macrophage in protracted bacterial bronchitis

Chen, Alice, Pena, Olga, Nel, Hanno, Pizzuto, Susan, Petsky, Helen, Gardiner, Samantha, Yerkovich, Stephanie, Baines, Katie, Gibson, Peter, Hodge, Greg, Hodge, Sandra, Buntain, Helen, Chang, Anne and Upham, John (2016). Alveolar macrophage in protracted bacterial bronchitis. ERS International Congress 2016, London, United Kingdom, 2016. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2016.PA3977

Alveolar macrophage in protracted bacterial bronchitis

2016

Conference Publication

Prostaglandin D2 contributes to severity of pneumoviral bronchiolitis

Werder, R., Hodge, N., Lynch, J., Simpson, J., Zhang, V, Forbes-Blom, E., Upham, J., Spann, K., Everard, M. and Phipps, S. (2016). Prostaglandin D2 contributes to severity of pneumoviral bronchiolitis. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA Australia, 1-6 April 2016. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.

Prostaglandin D2 contributes to severity of pneumoviral bronchiolitis

2016

Conference Publication

Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening Type I and III interferon production

Werder, R. B., Lynch, J., Simpson, J., Loh, Z., Zhang, V., Spann, K., Sly, P., Mazzone, S., Upham, J. and Phipps, S. (2016). Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening Type I and III interferon production. 4th Annual Meeting of The International Cytokine and Interferon Society (ICIS), San Francisco, CA, United States, October 16 - 19 2016. London, United Kingdom: Academic Press.

Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening Type I and III interferon production

2016

Conference Publication

The Lung Microbiota In Stable Adult Asthma Differs According To Inflammatory Phenotype, Sex, And Atopy

Rogers, G. B., Leong, L. E., Gibson, P. G., Yang, I. A., Hodge, S. J., Reynolds, P. N., James, A. L., Upham, J. W., Jenkins, C., Peters, M., Baraket, M. and Simpsons, J. L. (2016). The Lung Microbiota In Stable Adult Asthma Differs According To Inflammatory Phenotype, Sex, And Atopy. International Conference of the American-Thoracic-Society (ATS), San Francisco, Ca, United States, May 13-18, 2016. NEW YORK: AMER THORACIC SOC.

The Lung Microbiota In Stable Adult Asthma Differs According To Inflammatory Phenotype, Sex, And Atopy

2016

Journal Article

Blood cytotoxic/inflammatory mediators in non-eosinophilic asthma

Hodge, S., Hodge, G., Simpson, J. L., Yang, I. A., Upham, J., James, A., Gibson, P. G. and Reynolds, P. N. (2016). Blood cytotoxic/inflammatory mediators in non-eosinophilic asthma. Clinical and Experimental Allergy, 46 (1), 60-70. doi: 10.1111/cea.12634

Blood cytotoxic/inflammatory mediators in non-eosinophilic asthma

2016

Conference Publication

Plasmacytoid Dendritic Cells Play a Critical Role in Regulating Rhinovirus Induced Gene Expression Pathways

Upham, J., Xi, Y., Pena, O. and Bosco, A. (2016). Plasmacytoid Dendritic Cells Play a Critical Role in Regulating Rhinovirus Induced Gene Expression Pathways. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA Australia, 1-6 April 2016. HOBOKEN: European Respiratory Society. doi: 10.1183/13993003.congress-2016.pp236

Plasmacytoid Dendritic Cells Play a Critical Role in Regulating Rhinovirus Induced Gene Expression Pathways

2016

Conference Publication

Plasmacytoid Dendritic Cells Play A Critical Role In Regulating Gene Expression Patterns Induced By Human Rhinoviruses

Upham, J., Xi, C., Pena, O. and Bosco, A. (2016). Plasmacytoid Dendritic Cells Play A Critical Role In Regulating Gene Expression Patterns Induced By Human Rhinoviruses. International Conference of the American-Thoracic-Society (ATS), San Francisco Ca United States, 13-18 May 2016. New York, NY United States: American Thoracic Society.

Plasmacytoid Dendritic Cells Play A Critical Role In Regulating Gene Expression Patterns Induced By Human Rhinoviruses

2016

Conference Publication

Clinical Effectiveness Of Omalizumab In Severe Allergic Asthma Above The Recommended Dosing Range: The Australian Xolair Registry

Hew, M., Gillman, A., Sutherland, M., Wark, P., Bowden, J., McDonald, V., Guo, M., Reddel, H., Jenkins, C., Marks, G., Upham, J., Thien, F., Rimmer, J., Katsoulotos, G. P., Cook, M., Yang, I., Katelaris, C., Bowler, S., Langton, D., Gibson, P. G., Robinson, P. D., Wright, C., Bint, M., Yozghatlian, V., Burgess, S., Sivakumaran, P., Jaffe, A., Yan, K., Peters, M. ... Aminazad, A. (2016). Clinical Effectiveness Of Omalizumab In Severe Allergic Asthma Above The Recommended Dosing Range: The Australian Xolair Registry. International Conference of the American-Thoracic-Society (ATS), San Francisco Ca, May 13-18, 2016. NEW YORK: AMER THORACIC SOC.

Clinical Effectiveness Of Omalizumab In Severe Allergic Asthma Above The Recommended Dosing Range: The Australian Xolair Registry

2016

Conference Publication

Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening type I and III interferon production

Werder, R., Lynch, J., Simpson, J., Loh, Z., Zhang, V., Spann, K., Sly, P., Mazzone, S., Upham, J. and Phipps, S. (2016). Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening type I and III interferon production. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200

Aeroallergen-induced IL-33 predisposes to respiratory virus-induced asthma by dampening type I and III interferon production

2015

Journal Article

Rhinovirus stimulated IFN-α production: how important are plasmacytoid DCs, monocytes and endosomal pH?

Xi, Yang, Finlayson, Arvid, White, Oliva J., Carroll, Melanie L. and Upham, John W. (2015). Rhinovirus stimulated IFN-α production: how important are plasmacytoid DCs, monocytes and endosomal pH?. Clinical and Translational Immunology, 4 (10) e46, e46. doi: 10.1038/cti.2015.27

Rhinovirus stimulated IFN-α production: how important are plasmacytoid DCs, monocytes and endosomal pH?