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2020

Conference Publication

Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection

Hasnain, S., Wang, R., Taylor, S., Wong, K. Y., Moniruzzaman, M., Upham, J., Spann, K., Mcguckin, M. A., Burr, L. and Phipps, S. (2020). Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection. TSANZSRS 2020 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, VIC, Australia, 27–31 March 2020. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/resp.13777

Harnessing the therapeutic potential of interleukin-22 in neonatal respiratory viral infection

2020

Journal Article

The impact of new universal child influenza programs in Australia: Vaccine coverage, effectiveness and disease epidemiology in hospitalised children in 2018

Blyth, Christopher C., Cheng, Allen C., Crawford, Nigel W., Clark, Julia E., Buttery, Jim P., Marshall, Helen S., Francis, Joshua R., McRae, Jocelynne, Kotsimbos, Tom, Kelly, Paul M., Macartney, Kristine K., on behalf of the Paediatric Active Enhanced Disease Surveillance (PAEDS), Influenza Complications Alert Network (FluCAN) Collaboration and Upham, John (2020). The impact of new universal child influenza programs in Australia: Vaccine coverage, effectiveness and disease epidemiology in hospitalised children in 2018. Vaccine, 38 (13), 2779-2787. doi: 10.1016/j.vaccine.2020.02.031

The impact of new universal child influenza programs in Australia: Vaccine coverage, effectiveness and disease epidemiology in hospitalised children in 2018

2020

Conference Publication

FC Gamma receptor (FCGR) I expression is increased in severe asthma particularly in participants with non-eosinophilic airway inflammation

Gupta, S., Fricker, M., Xi, Y., Grainge, C., Upham, J. and Simpson, J. (2020). FC Gamma receptor (FCGR) I expression is increased in severe asthma particularly in participants with non-eosinophilic airway inflammation. TSANZSRS 2020 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, QLD Australia, 27-31 March 2020. Hoboken, NJ USA: Wiley.

FC Gamma receptor (FCGR) I expression is increased in severe asthma particularly in participants with non-eosinophilic airway inflammation

2020

Conference Publication

Factors associated with respiratory infection frequency in healthy and asthmatic adults differ between women and men

Upham, J., Murray, L. and Xi, Y. (2020). Factors associated with respiratory infection frequency in healthy and asthmatic adults differ between women and men. TSANZSRS 2020 The Australia & New Zealand Society of Respiratory Science and The Thoracic Society of Australia and New Zealand (ANZSRS/TSANZ) Annual Scientific Meeting for Leaders in Lung Health & Respiratory Science, Melbourne, QLD Australia, 27-31 March 2020. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia.

Factors associated with respiratory infection frequency in healthy and asthmatic adults differ between women and men

2019

Journal Article

Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2018: the Influenza Complications Alert Network (FluCAN)

Cheng, Allen C., Holmes, Mark, Dwyer, Dominic E., Senanayake, Sanjaya, Cooley, Louise, Irving, Louis B., Simpson, Graham, Korman, Tony, Macartney, Kristine, Friedman, N. Deborah, Wark, Peter, Howell, Anna, Blyth, Christopher C., Crawford, Nigel, Buttery, Jim, Bowler, Simon, Upham, John W., Waterer, Grant W., Kotsimbos, Tom and Kelly, Paul M. (2019). Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2018: the Influenza Complications Alert Network (FluCAN). Communicable Diseases Intelligence Quarterly Report, 43. doi: 10.33321/cdi.2019.43.48

Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2018: the Influenza Complications Alert Network (FluCAN)

2019

Journal Article

Rational oral corticosteroid use in adult severe asthma: a narrative review

Chung, Li Ping, Upham, John W., Bardin, Philip G. and Hew, Mark (2019). Rational oral corticosteroid use in adult severe asthma: a narrative review. Respirology, 25 (2) resp.13730, 161-172. doi: 10.1111/resp.13730

Rational oral corticosteroid use in adult severe asthma: a narrative review

2019

Journal Article

The effect of glucocorticoids on Thrombospondin-1, Osteocalcin and the Thrombospondin-1:Osteocalcin ratio in humans

Cesana-Nigro, Nicole, Keshvari, Sahar, Barclay, Johanna L., Sorbello, Jane, Upham, John W., Benham, Helen, Anderson, Stephen T., Steiger, Natasha, Prins, Johannes B. and Inder, Warrick J. (2019). The effect of glucocorticoids on Thrombospondin-1, Osteocalcin and the Thrombospondin-1:Osteocalcin ratio in humans. Clinical Endocrinology, 91 (6) cen.14108, 728-736. doi: 10.1111/cen.14108

The effect of glucocorticoids on Thrombospondin-1, Osteocalcin and the Thrombospondin-1:Osteocalcin ratio in humans

2019

Journal Article

Airway pharmacology: treatment options and algorithms to treat patients with chronic obstructive pulmonary disease

Kerstjens, Huib A. M., Upham, John W. and Yang, Ian A. (2019). Airway pharmacology: treatment options and algorithms to treat patients with chronic obstructive pulmonary disease. Journal of Thoracic Disease, 11 (S17), S2200-S2209. doi: 10.21037/jtd.2019.10.57

Airway pharmacology: treatment options and algorithms to treat patients with chronic obstructive pulmonary disease

2019

Journal Article

Efficacy of azithromycin in severe asthma from the AMAZES randomised trial

Gibson, Peter G., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa, Powell, Heather and Simpson, Jodie L. (2019). Efficacy of azithromycin in severe asthma from the AMAZES randomised trial. ERJ Open Research, 5 (4) 00056-2019, 00056-2019. doi: 10.1183/23120541.00056-2019

Efficacy of azithromycin in severe asthma from the AMAZES randomised trial

2019

Conference Publication

Azithromycin add-on therapy reduces airway inflammation and extracellular DNA: An AMAZES sub-study

Simpson, Jodie, Barker, Daniel, Yang, Ian, Upham, John, Reynolds, Paul, Hodge, Sandra, James, Alan, Jenkins, Christine, Peters, Matthew, Marks, Guy, Baraket, Melissa and Gibson, Peter (2019). Azithromycin add-on therapy reduces airway inflammation and extracellular DNA: An AMAZES sub-study. European-Respiratory-Society (ERS) International Congress, Madrid, Spain, 28 September-2 October 2019. Sheffield, United Kingdom: European Respiratory Society. doi: 10.1183/13993003.congress-2019.OA5338

Azithromycin add-on therapy reduces airway inflammation and extracellular DNA: An AMAZES sub-study

2019

Conference Publication

Baseline predictors of being exacerbation-free during 2 years of benralizumab treatment

Upham, John W., Jackson, David J., Barker, Peter, Newbold, Paul and Cook, William (2019). Baseline predictors of being exacerbation-free during 2 years of benralizumab treatment. European-Respiratory-Society (ERS) International Congress, Madrid, Spain, 28 September - 2 October 2019. Sheffield, United Kingdom: European Respiratory Society. doi: 10.1183/13993003.congress-2019.OA5337

Baseline predictors of being exacerbation-free during 2 years of benralizumab treatment

2019

Journal Article

Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2017: the Influenza Complications Alert Network (FluCAN)

Cheng, Allen C., Holmes, Mark, Dwyer, Dominic E., Senanayake, Sanjaya, Cooley, Louise, Irving, Louis B., Simpson, Graham, Korman, Tony, Macartney, Kristine, Friedman, N Deborah, Wark, Peter, Howell, Anna, Blyth, Christopher C., Bowler, Simon, Upham, John, Waterer, Grant W., Kotsimbos, Tom and Kelly, Paul M. (2019). Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2017: the Influenza Complications Alert Network (FluCAN). Communicable Diseases Intelligence, 43. doi: 10.33321/cdi.2019.43.39

Influenza epidemiology in patients admitted to sentinel Australian hospitals in 2017: the Influenza Complications Alert Network (FluCAN)

2019

Journal Article

Long-term azithromycin reduces Haemophilus influenzae and increases antibiotic resistance in severe asthma

Taylor, Steven L., Leong, Lex E. X., Mobegi, Fredrick M., Choo, Jocelyn M., Wesselingh, Steve, Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Baraket, Melissa, Marks, Guy B., Gibson, Peter G., Rogers, Geraint B. and Simpson, Jodie L. (2019). Long-term azithromycin reduces Haemophilus influenzae and increases antibiotic resistance in severe asthma. American Journal of Respiratory and Critical Care Medicine, 200 (3), 309-317. doi: 10.1164/rccm.201809-1739OC

Long-term azithromycin reduces Haemophilus influenzae and increases antibiotic resistance in severe asthma

2019

Journal Article

Effects of interleukin‐6 receptor blockade on allergen‐induced airway responses in mild asthmatics

Revez, Joana A., Bain, Lisa M., Watson, Rick M., Towers, Michelle, Collins, Tina, Killian, Kieran J., O'Byrne, Paul M., Gauvreau, Gail M., Upham, John W. and Ferreira, Manuel A. R. (2019). Effects of interleukin‐6 receptor blockade on allergen‐induced airway responses in mild asthmatics. Clinical & Translational Immunology, 8 (6) e1044, e1044. doi: 10.1002/cti2.1044

Effects of interleukin‐6 receptor blockade on allergen‐induced airway responses in mild asthmatics

2019

Journal Article

HOspitalised Pneumonia Extended (HOPE) Study to reduce the long-term effects of childhood pneumonia: protocol for a multicentre, double-blind, parallel, superiority randomised controlled trial

Chang, Anne B., Fong, Siew Moy, Yeo, Tsin Wen, Ware, Robert S., McCallum, Gabrielle B., Nathan, Anna M., Ooi, Mong H., de Bruyne, Jessie, Byrnes, Catherine A., Lee, Bilawara, Nachiappan, Nachal, Saari, Noorazlina, Torzillo, Paul, Smith-Vaughan, Heidi, Morris, Peter S., Upham, John W. and Grimwood, Keith (2019). HOspitalised Pneumonia Extended (HOPE) Study to reduce the long-term effects of childhood pneumonia: protocol for a multicentre, double-blind, parallel, superiority randomised controlled trial. BMJ Open, 9 (4) e026411, e026411. doi: 10.1136/bmjopen-2018-026411

HOspitalised Pneumonia Extended (HOPE) Study to reduce the long-term effects of childhood pneumonia: protocol for a multicentre, double-blind, parallel, superiority randomised controlled trial

2019

Journal Article

Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report

McDonald, Vanessa M., Fingleton, James, Agusti, Alvar, Hiles, Sarah A., Clark, Vanessa L., Holland, Anne E., Marks, Guy B., Bardin, Philip P., Beasley, Richard, Pavord, Ian D., Wark, Peter A.B., Gibson, Peter G., Treatable Traits Down Under International Workshop, Agusti, Alvar, Anderson, Gary, Bardin, Philip P., Beasley, Richard, Cheng, Allen, Chung, Li Ping, Clark, Vanessa L., Dabscheck, Eli, Dharmage, Shyamali, Fingleton, James, Gibson, Peter, Hardy, Jo, Hew, Mark, Hiles, Sarah A., Holland, Anne E., James, Alan ... Wark, Peter A.B. (2019). Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report. European Respiratory Journal, 53 (5) 1802058, 1802058. doi: 10.1183/13993003.02058-2018

Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report

2019

Journal Article

Contemporary Concise Review 2018: asthma and chronic obstructive pulmonary disease: asthma and COPD

Upham, John W. (2019). Contemporary Concise Review 2018: asthma and chronic obstructive pulmonary disease: asthma and COPD. Respirology, 24 (7) resp.13553, 693-699. doi: 10.1111/resp.13553

Contemporary Concise Review 2018: asthma and chronic obstructive pulmonary disease: asthma and COPD

2019

Journal Article

Multiple respiratory microbiota profiles are associated with lower airway inflammation in children with protracted bacterial bronchitis

Marsh, Robyn L., Smith-Vaughan, Heidi C., Chen, Alice C.H., Marchant, Julie M., Yerkovich, Stephanie T., Gibson, Peter G., Pizzutto, Susan J., Hodge, Sandra, Upham, John W. and Chang, Anne B. (2019). Multiple respiratory microbiota profiles are associated with lower airway inflammation in children with protracted bacterial bronchitis. Chest, 155 (4), 778-786. doi: 10.1016/j.chest.2019.01.002

Multiple respiratory microbiota profiles are associated with lower airway inflammation in children with protracted bacterial bronchitis

2019

Journal Article

A sputum 6-gene signature predicts future exacerbations of poorly controlled asthma

Fricker, Michael, Gibson, Peter G., Powell, Heather, Simpson, Jodie L., Yang, Ian A., Upham, John W., Reynolds, Paul N., Hodge, Sandra, James, Alan L., Jenkins, Christine, Peters, Matthew J., Marks, Guy B., Baraket, Melissa and Baines, Katherine J. (2019). A sputum 6-gene signature predicts future exacerbations of poorly controlled asthma. Journal of Allergy and Clinical Immunology, 144 (1), 51-60.e11. doi: 10.1016/j.jaci.2018.12.1020

A sputum 6-gene signature predicts future exacerbations of poorly controlled asthma

2019

Conference Publication

Innate immune interactions of human rhinovirus-16 and grass pollen in grass pollen allergic adults

Kailaivasan, T. H., Nouri, H., Upham, J. and Davies, J. M. (2019). Innate immune interactions of human rhinovirus-16 and grass pollen in grass pollen allergic adults. Congress of the European Academy of Allergy and Clinical Immunology (EAACI), Lisbon Portugal, 1-5 June, 2019. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/all.13962

Innate immune interactions of human rhinovirus-16 and grass pollen in grass pollen allergic adults