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2011 Journal Article Noninvasive tools to assess liver diseaseClark, Paul J. and Patel, Keyur (2011). Noninvasive tools to assess liver disease. Current Opinion in Gastroenterology, 27 (3), 210-216. doi: 10.1097/MOG.0b013e328343e9a3 |
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2011 Conference Publication Il28B C/c Genotype Is Predictive of >= 1 Log10 Iu/ml Reduction in Plasma Hcv Rna After 4 Weeks of Peginterferon (Pegifn) and Ribavirin (Rbv) Therapy: Implications for the Use of the Lead-In Strategy for Direct-Acting Antiviral-Based Treatment RegimensThompson, Alexander J., Clark, Paul J., Tillmann, Hans L., Patel, Keyur, Naggie, Susanna, Poordad, F. Fred, Lawitz, Eric, Bacon, Bruce R., Vierling, John M., Noviello, Stephanie, Brass, Clifford A., Albrecht, Janice K., Goldstein, David B., McHutchison, John G., Sulkowski, Mark S. and Muir, Andrew J. (2011). Il28B C/c Genotype Is Predictive of >= 1 Log10 Iu/ml Reduction in Plasma Hcv Rna After 4 Weeks of Peginterferon (Pegifn) and Ribavirin (Rbv) Therapy: Implications for the Use of the Lead-In Strategy for Direct-Acting Antiviral-Based Treatment Regimens. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL. |
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2011 Conference Publication The Relationship Between Hepatic Steatosis and Il28B Response in Patients with Chronic Hepatitis CTillmann, H. L., Patel, K., Muir, A., Guy, C., Li, J. H., Lao, X. Q., Thompson, A. J., Clark, P. J., Gardner, S. D., McHutchison, J. G. and McCarthy, J. J. (2011). The Relationship Between Hepatic Steatosis and Il28B Response in Patients with Chronic Hepatitis C. 46th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Berlin Germany, 2011. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(11)61348-2 |
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2011 Journal Article IL28B polymorphisms and treatment of hepatitis CClark, Paul J., Thompson, Alexander J. V. and Muir, Andrew J. (2011). IL28B polymorphisms and treatment of hepatitis C. Current Hepatitis Reports, 10 (1), 70-78. doi: 10.1007/s11901-010-0061-3 |
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2011 Journal Article IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: The future of personalized HCV therapiesClark, Paul J., Thompson, Alex J. and McHutchison, John G. (2011). IL28B genomic-based treatment paradigms for patients with chronic hepatitis C infection: The future of personalized HCV therapies. American Journal of Gastroenterology, 106 (1), 38-45. doi: 10.1038/ajg.2010.370 |
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2011 Conference Publication PREDICTING PEGINTERFERON-alpha AND RIBAVIRIN TREATMENT RESPONSE IN GENOTYPE 1 HCV PATIENTS - SIMPLE NOMOGRAMS TO SUPPORT CLINICIANSThompson, Alexander J., Clark, Paul J., Vock, David M., Pfeiffer, Ruth, Tillmann, Hans L., Patel, Keyur, Naggie, Susanna, Poordad, F. Fred, Nyberg, Lisa M., Noviello, Stephanie, Pedicone, Lisa, Brass, Clifford A., Albrecht, Janice K., Goldstein, David B., McHutchison, John G., O'Brien, Thomas R., Sulkowski, Mark S. and Muir, Andrew J. (2011). PREDICTING PEGINTERFERON-alpha AND RIBAVIRIN TREATMENT RESPONSE IN GENOTYPE 1 HCV PATIENTS - SIMPLE NOMOGRAMS TO SUPPORT CLINICIANS. 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco Ca, Nov 04-08, 2011. MALDEN: WILEY-BLACKWELL. |
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2011 Conference Publication Thyroid Stimulating Hormone (TSH) and Peginterferon Treatment Induced Hypothyroidism May Be Associated With Phosphodiesterase Polymorphisms in Patients With Chronic Hepatitis CClark, Paul, Thompson, Alexander J., Zhu, Mingfu, Ge, Dongliang, Shianna, Kevin, Tillmann, Hans L., Patel, Keyur, Urban, Thomas, Singh, Abanish, Sulkowski, Mark, Afdhal, Nezam, Jacobson, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric J., McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg, Lee, William M., Reindollar, Robert W., King, John W., Kwo, Paul Y., Ghalib, Reem H., Freilich, Bradley, Nyberg, Lisa M., Noviello, Stephanie, Boparai, Navdeep, Koury, Kenneth, Pedicone, Lisa D. and Brass, Clifford A. (2011). Thyroid Stimulating Hormone (TSH) and Peginterferon Treatment Induced Hypothyroidism May Be Associated With Phosphodiesterase Polymorphisms in Patients With Chronic Hepatitis C. Conference on Digestive Disease Week 2011, Chicago Il, May 07-10, 2011. PHILADELPHIA: W B SAUNDERS CO-ELSEVIER INC. |
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2010 Journal Article Hepatitis C trials that combine investigational agents with pegylated interferon should be stratified by interleukin-28B genotypeThomison, Allxander J., Muir, Andrew J., Sulkowski, Mark. S., Path, Keyur, Jilimann, Hans L., Clark, Paul J., Naccie, Susanna, Fellay, Jacques, Ge, Dongliang, McCarthy, Jlanlite J., Goldslin, David B. and McHutchison, John G. (2010). Hepatitis C trials that combine investigational agents with pegylated interferon should be stratified by interleukin-28B genotype. Hepatology, 52 (6), 2243-2244. doi: 10.1002/hep.23826 |
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2010 Conference Publication Variants in the Itpa Gene Protect Against Early Ribavirin-Induced Hemolytic Anemia in Hiv/hcv Co-Infected PatientsNaggie, Susanna, Rallon, Norma I., Benito, Jose M., Morello, Judith, Rodriguez-Novoa, Sonia, Clark, Paul J., Thompson, Alexander J., Shianna, Kevin, Vispo, Eugenia, McHutchison, John G., Goldstein, David B. and Soriano, Vincent (2010). Variants in the Itpa Gene Protect Against Early Ribavirin-Induced Hemolytic Anemia in Hiv/hcv Co-Infected Patients. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL. |
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2010 Journal Article Hepatitis C virus nonstructural protein 5A inhibitors: Novel target - Now for new trials and new treatment strategiesThompson, Alex J., Clark, Paul J. and McHutchison, John G. (2010). Hepatitis C virus nonstructural protein 5A inhibitors: Novel target - Now for new trials and new treatment strategies. Hepatology, 52 (3), 1162-1164. doi: 10.1002/hep.23853 |
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2010 Journal Article The diagnosis and management of hereditary haemochromatosisClark, Paul, Britton, Laurence J. and Powell, Lawrie W. (2010). The diagnosis and management of hereditary haemochromatosis. Clinical Biochemist Reviews, 31 (1), 3-8. |
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2010 Journal Article Genetic variation in IL28B: Impact on drug development for chronic hepatitis C infectionClark, P. J., Thompson, A. J. V. and McHutchison, J. G. (2010). Genetic variation in IL28B: Impact on drug development for chronic hepatitis C infection. Clinical Pharmacology and Therapeutics, 88 (5), 708-711. doi: 10.1038/clpt.2010.185 |
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2010 Conference Publication Common Genetic Variants Do Not Associate with Ifn-Induced Neutropenia in a Genome-Wide Association Study of Chronic Hepatitis C Patients in the Ideal StudyThompson, Alexander J., Clark, Paul J., Singh, Abanish, Ge, Dongliang, Fellay, Jacques, Sulkowski, Mark S., Muir, Andrew J., Tillman, Hans L., Patel, Keyur, Naggie, Susanna, Shianna, Kevin, Afdhal, Nezam H., Jacobson, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric, McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg Wayne, King, John W., Kwo, Paul Y., Nyberg, Lisa, Noviello, Stephanie, Boparai, Navdeep, Koury, Kenneth J., Pedicone, Lisa, Brass, Clifford A., Albrecht, Janice K., Goldstein, David B. and McHutchison, John G. (2010). Common Genetic Variants Do Not Associate with Ifn-Induced Neutropenia in a Genome-Wide Association Study of Chronic Hepatitis C Patients in the Ideal Study. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL. |
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2010 Conference Publication Il28B Genetic Polymorphism Has Genome Wide Significant Associations with Serum Low Density Lipoprotein Levels and Hepatic Steatosis in Patients with Genotype 1 Chronic Hepatitis C (Chc)Clark, Paul J., Thompson, Alexander J., Zhu, Mingfu, Zhu, Qianqian, Ge, Dongliang, Sulkowski, Mark S., Tillmann, Hans L., Patel, Keyur, Naggie, Susanna, Muir, Andrew J., Afdhal, Nezam H., Jacobson, Ira M., Esteban, Rafael, Lawitz, Eric, Poordad, Fred, Shiffman, Mitchell L., Galler, Greg Wayne, Harrison, Stephen, King, John W., Kwo, Paul Y., Nyberg, Lisa M., McCone, Jonathan, Lee, William M., Reindollar, Robert, Ghalib, Reem H., Freilich, Bradley, Goodman, Zachary, Boparai, Navdeep, Koury, Kenneth J. ... McHutchison, John G. (2010). Il28B Genetic Polymorphism Has Genome Wide Significant Associations with Serum Low Density Lipoprotein Levels and Hepatic Steatosis in Patients with Genotype 1 Chronic Hepatitis C (Chc). 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL. |
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2010 Conference Publication Itpa Genetic Variants Are Protective Against Anemia During Antiviral Therapy for G2/3 Hcv, But Do Not Decrease the Need for Rbv Dose Reduction or Increase SvrThompson, Alexander J., Santoro, Rosanna, Piazzolla, Valeria, Tillman, Hans L., Patel, Keyur, Clark, Paul J., Naggie, Susanna, Shianna, Kevin, Mottola, Leonardo, Petruzzellis, Daniela, Romano, Mario, Sogari, Fernando, Facciorusso, Domenico, Goldstein, David B., McHutchison, John G. and Mangia, Alessandra (2010). Itpa Genetic Variants Are Protective Against Anemia During Antiviral Therapy for G2/3 Hcv, But Do Not Decrease the Need for Rbv Dose Reduction or Increase Svr. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL. |
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2010 Conference Publication Genome Wide-Association Study Identifies Il28B Polymorphism to Be Associated with Baseline Alt and Hepatic Necro-Inflammatory Activity in Chronic Hepatitis C Patients Enrolled in the Ideal StudyThompson, Alexander J., Clark, Paul J., Zhu, Mingfu, Zhu, Qianqian, Ge, Dongliang, Sulkowski, Mark S., Muir, Andrew J., Tillmann, Hans L., Patel, Keyur, Naggie, Susanna, Afdhal, Nezam H., Jacobsons, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric, McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg Wayne, King, John W., Kwo, Paul Y., Nyberg, Lisa Marie, Goodman, Zachary, Noviello, Stephanie, Boparai, Navdeep, Koury, Kenneth J., Pedicone, Lisa, Brass, Clifford, Albrecht, Janice K., Goldstein, David B. and McHutchison, John G. (2010). Genome Wide-Association Study Identifies Il28B Polymorphism to Be Associated with Baseline Alt and Hepatic Necro-Inflammatory Activity in Chronic Hepatitis C Patients Enrolled in the Ideal Study. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL. |
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2010 Conference Publication Il28B Genotype Is Not Associated with Advanced Hepatic Fibrosis in Chronic Hepatitis C Patients Enrolled in the Ideal StudyThompson, Alexander J., Clark, Paul J., Fellay, Jacques, Muir, Andrew J., Tillmann, Hans L., Patel, Keyur, Naggie, Susanna, Afdhal, Nezam H., Jacobson, Ira M., Esteban, Rafael, Poordad, Fred, Lawitz, Eric, McCone, Jonathan, Shiffman, Mitchell L., Galler, Greg Wayne, King, John W., Kwo, Paul Y., Nyberg, Lisa M., Goodman, Zachary, Noviello, Stephanie, Boparai, Navdeep, Koury, Kenneth J., Pedicone, Lisa, Brass, Clifford A., Albrecht, Janice K., Goldstein, David B., McHutchison, John G. and Sulkowski, Mark S. (2010). Il28B Genotype Is Not Associated with Advanced Hepatic Fibrosis in Chronic Hepatitis C Patients Enrolled in the Ideal Study. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL. |
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2010 Conference Publication Clinical and Histological Predictors of Discordance Between the Fibrotest and Fibroscan: Analysis of the Achieve CohortsClark, Paul J., Thompson, Alexander J., Tillmann, Hans L., Torbenson, Michael, Pulkstenis, Erik, Subramanian, Mani, McHutchison, John G. and Patel, Keyur (2010). Clinical and Histological Predictors of Discordance Between the Fibrotest and Fibroscan: Analysis of the Achieve Cohorts. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL. |
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2010 Conference Publication HEPATITIS C TRIALS THAT COMBINE INVESTIGATIONAL AGENTS WITH PEGYLATED-INTERFERON-alpha SHOULD BE STRATIFIED BY IL28B GENOTYPEThompson, Alexander J., Muir, Andrew J., Sulkowski, Mark S., Patel, Keyur, Tillmann, Hans L., Clark, Paul J., Naggie, Susanna, Fellay, Jacques, Ge, Dongliang, McCarthy, Jeanette, Goldstein, David B. and McHutchison, John G. (2010). HEPATITIS C TRIALS THAT COMBINE INVESTIGATIONAL AGENTS WITH PEGYLATED-INTERFERON-alpha SHOULD BE STRATIFIED BY IL28B GENOTYPE. 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston Ma, Oct 29-Nov 02, 2010. MALDEN: WILEY-BLACKWELL. |
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2010 Conference Publication Independent Validation of the Safe Biopsy Algorithm: Analysis of the Achieve CohortsThompson, A., Clark, P., Tillmann, H., Torbenson, M., Pulkstenis, E., Subramanian, G. M., McHutchison, J. and Patel, K. (2010). Independent Validation of the Safe Biopsy Algorithm: Analysis of the Achieve Cohorts. 45th Annual Meeting of the European-Association-for-the-Study-of-the-Liver, Vienna Austria, Apr 14-18, 2010. AMSTERDAM: ELSEVIER SCIENCE BV. doi: 10.1016/S0168-8278(10)61085-9 |
