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2021

Journal Article

CSF1R-dependent macrophages control postnatal somatic growth and organ maturation

Keshvari, Sahar, Caruso, Melanie, Teakle, Ngari, Batoon, Lena, Sehgal, Anuj, Patkar, Omkar L., Ferrari-Cestari, Michelle, Snell, Cameron E., Chen, Chen, Stevenson, Alex, Davis, Felicity M., Bush, Stephen J., Pridans, Clare, Summers, Kim M., Pettit, Allison R., Irvine, Katharine M. and Hume, David A. (2021). CSF1R-dependent macrophages control postnatal somatic growth and organ maturation. PLoS Genetics, 17 (6) e1009605, e1009605. doi: 10.1371/journal.pgen.1009605

CSF1R-dependent macrophages control postnatal somatic growth and organ maturation

2021

Journal Article

Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1

Liu, T-Y, Bartnikowski, M., Wu, A. C., Veitch, M., Sokolowski, K. A., Millard, S. M., Pettit, A. R., Glatt, V., Evans, C. H. and Wells, J. W. (2021). Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1. European Cells and Materials, 41, 345-354. doi: 10.22203/eCM.v041a22

Healing of sub-critical femoral osteotomies in mice is unaffected by tacrolimus and deletion of recombination activating gene 1

2021

Journal Article

Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release

Starobova, Hana, Monteleone, Mercedes, Adolphe, Christelle, Batoon, Lena, Sandrock, Cheyenne J., Tay, Bryan, Deuis, Jennifer R., Smith, Alexandra V., Mueller, Alexander, Nadar, Evelyn Israel, Lawrence, Grace Pamo, Mayor, Amanda, Tolson, Elissa, Levesque, Jean-Pierre, Pettit, Allison R., Wainwright, Brandon J., Schroder, Kate and Vetter, Irina (2021). Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release. Journal of Experimental Medicine, 218 (5) e20201452. doi: 10.1084/jem.20201452

Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release

2021

Journal Article

Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice

Kaur, Simranpreet, Sehgal, Anuj, Wu, Andy C., Millard, Susan M., Batoon, Lena, Sandrock, Cheyenne J., Ferrari-Cestari, Michelle, Levesque, Jean-Pierre, Hume, David A., Raggatt, Liza J. and Pettit, Allison R. (2021). Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice. Journal of Hematology and Oncology, 14 (1) 3, 1-19. doi: 10.1186/s13045-020-00997-w

Stable colony-stimulating factor 1 fusion protein treatment increases hematopoietic stem cell pool and enhances their mobilisation in mice

2020

Journal Article

A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte system

Grabert, Kathleen, Sehgal, Anuj, Irvine, Katharine M., Wollscheid-Lengeling, Evi, Ozdemir, Derya D., Stables, Jennifer, Luke, Garry A., Ryan, Martin D., Adamson, Antony, Humphreys, Neil E., Sandrock, Cheyenne J., Rojo, Rocio, Verkasalo, Veera A., Mueller, Werner, Hohenstein, Peter, Pettit, Allison R., Pridans, Clare and Hume, David A. (2020). A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte system. Journal of Immunology, 205 (11), 3154-3166. doi: 10.4049/jimmunol.2000835

A transgenic line that reports CSF1R protein expression provides a definitive marker for the mouse mononuclear phagocyte system

2020

Conference Publication

3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice

Kaur, Simranpreet, Sehgal, Anuj, Wu, Andy, Millard, Susan, Batoon, Lena, Sandrock, Cheyenne, Levesque, Jean-Pierre, Hume, David, Raggatt, Liza and Pettit, Allison (2020). 3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice. 49th Annual Scientific Meeting of the ISEH - International Society for Experimental Hematology, New York, NY USA, 20-23 August 2020. Philadelphia, PA USA: Elsevier. doi: 10.1016/j.exphem.2020.09.105

3092 – Stable colony stimulating factor 1 fusion protein treatment increases the hematopoietic stem cell pool and enhances their mobilization in mice

2020

Journal Article

Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow

Tay, Joshua, Bisht, Kavita, McGirr, Crystal, Millard, Susan M., Pettit, Allison R., Winkler, Ingrid G. and Levesque, Jean-Pierre (2020). Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow. Experimental Hematology, 82, 33-42. doi: 10.1016/j.exphem.2020.02.003

Imaging flow cytometry reveals that granulocyte colony-stimulating factor treatment causes loss of erythroblastic islands in the mouse bone marrow

2019

Journal Article

Deformation behavior of porous PHBV scaffold in compression: A finite element analysis study

Patel, Rushabh, Lu, Mingyuan, Diermann, Sven Heinrich, Wu, Andy, Pettit, Allison and Huang, Han (2019). Deformation behavior of porous PHBV scaffold in compression: A finite element analysis study. Journal of the Mechanical Behavior of Biomedical Materials, 96, 1-8. doi: 10.1016/j.jmbbm.2019.04.030

Deformation behavior of porous PHBV scaffold in compression: A finite element analysis study

2019

Journal Article

Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury

Alexander, Kylie A., Tseng, Hsu-Wen, Fleming, Whitney, Jose, Beulah, Salga, Marjorie, Kulina, Irina, Millard, Susan M., Pettit, Allison R., Genet, Francois and Levesque, Jean-Pierre (2019). Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury. Frontiers in Immunology, 10 (MAR) 377. doi: 10.3389/fimmu.2019.00377

Inhibition of JAK1/2 Tyrosine Kinases Reduces Neurogenic Heterotopic Ossification After Spinal Cord Injury

2019

Conference Publication

Osteal macrophage contributions to adult bone homeostasis and postmenopausal osteoporosis bone pathology

Pettit, Allison, Batoon, Lena, Millard, Susan, Wu, Andy and Raggatt, Liza (2019). Osteal macrophage contributions to adult bone homeostasis and postmenopausal osteoporosis bone pathology. Annual Meeting of the American Society for Bone and Mineral Research, Orlando, FL, United States, 20-23 September, 2019. Hoboken, NJ, United States: Wiley-Blackwell Publishing Asia.

Osteal macrophage contributions to adult bone homeostasis and postmenopausal osteoporosis bone pathology

2019

Conference Publication

Non-genotoxic conditioning facilitates tolerance induction through stable mixed hematopoietic chimerism of gene modified bone marrow

Hasan, M. A., Pettit, A. R. and Steptoe, R. J. (2019). Non-genotoxic conditioning facilitates tolerance induction through stable mixed hematopoietic chimerism of gene modified bone marrow. 17th International Congress of Immunology (IUIS), Beijing, China, 19-23 October, 2019. Weinheim, Germany: Wiley. doi: 10.1002/eji.201970400

Non-genotoxic conditioning facilitates tolerance induction through stable mixed hematopoietic chimerism of gene modified bone marrow

2018

Journal Article

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

Kaur, Simranpreet, Raggatt, Liza J., Millard, Susan M., Wu, Andy C., Batoon, Lena, Jacobsen, Rebecca N., Winkler, Ingrid G., MacDonald, Kelli P., Perkins, Andrew C., Hume, David A., Levesque, Jean-Pierre and Pettit, Allison R. (2018). Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment. Blood, 132 (7), 735-749. doi: 10.1182/blood-2018-01-829663

Self-repopulating recipient bone marrow resident macrophages promote long-term hematopoietic stem cell engraftment

2018

Conference Publication

Oncostatin M is a key effector of heterotopic ossification following spinal cord injuries

Tseng, Hsu-Wen, Alexander, Kylie, Kulina, Irina, Salga, Marjorie, Jose, Beulah, Genet, Francois, Torossian, Frederic, Guerton, Bernadette, Anginot, Adrienne, Fleming, Whitney, Millard, Susan, Pettit, Allison, Sims, Natalie, Lataillade, Jean-Jacques, Le Bousse-Kerdiles, Marie-Caroline and Levesque, Jean Pierre (2018). Oncostatin M is a key effector of heterotopic ossification following spinal cord injuries. Annual Meeting of the American Society for Bone and Mineral Research, Montreal Canada, September 28 - October 1 2018. Hoboken, NJ United States: Wiley.

Oncostatin M is a key effector of heterotopic ossification following spinal cord injuries

2018

Conference Publication

Granulocyte Colony Stimulating Factor impacts on osteomacs and bone marrow macrophages - implications for prostate cancer osteoblastic lesion formation

Millard, Susan, Wu, Andy, Kaur, Simran, He, Yaowu, Batoon, Lena, Hooper, John and Pettit, Allison (2018). Granulocyte Colony Stimulating Factor impacts on osteomacs and bone marrow macrophages - implications for prostate cancer osteoblastic lesion formation. Annual Meeting of the American Society for Bone and Mineral Research, Montréal, Quebéc, Canada, Sep 28-Oct 01, 2018. Hoboken, NJ, United States: Wiley-Blackwell Publishing. doi: 10.1002/jbmr.3621

Granulocyte Colony Stimulating Factor impacts on osteomacs and bone marrow macrophages - implications for prostate cancer osteoblastic lesion formation

2018

Conference Publication

Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation

Pettit, Allison, Kaur, Simranpreet, Raggatt, Liza, Millard, Susan, Wu, Andy, Batoon, Lena, Jacobsen, Rebecca, Winkler, Ingrid, MacDonald, Kelli, Perkins, Andrew, Hume, David and Levesque, Jean-Pierre (2018). Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation. 47th Annual Scientific Meeting of the International Society for Experimental Hematology, Los Angeles, CA, United States, 23-26 August 2018. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2018.06.117

Self-repopulating recipient bone marrow recipient macrophages promote hematopoietic stem cell engraftment post autologous transplantation

2017

Journal Article

Macrophages Driving Heterotopic Ossification: Convergence of Genetically-Driven and Trauma-Driven Mechanisms

Levesque, Jean-Pierre, Sims, Natalie A., Pettit, Allison R., Alexander, Kylie A., Tseng, Hsu-Wen, Torossian, Frédéric, Genêt, François, Lataillade, Jean-Jacques and Le Bousse-Kerdilès, Marie-Caroline (2017). Macrophages Driving Heterotopic Ossification: Convergence of Genetically-Driven and Trauma-Driven Mechanisms. Journal of Bone and Mineral Research, 33 (2), 365-366. doi: 10.1002/jbmr.3346

Macrophages Driving Heterotopic Ossification: Convergence of Genetically-Driven and Trauma-Driven Mechanisms

2017

Journal Article

Macrophage-derived oncostatin M contributes to human and mouse neurogenic heterotopic ossifications

Torossian, Frédéric, Guerton, Bernadette, Anginot, Adrienne, Alexander, Kylie A., Desterke, Christophe , Soave, Sabrina, Tseng, Hsu-Wen, Arouche, Nassim, Boutin, Laetitia, Kulina, Irina, Salga, Marjorie, Jose, Beulah, Pettit, Allison R., Clay, Denis, Rochet, Nathalie, Vlachos, Erica, Genet, Guillaume, Debaud, Charlotte, Denormandie, Philippe, Genet, François, Sims, Natalie A., Banzet, Sébastien, Levesque, Jean-Pierre, Lataillade, Jean-Jacques and Le Bousse-Kerdilès, Marie-Caroline (2017). Macrophage-derived oncostatin M contributes to human and mouse neurogenic heterotopic ossifications. JCI Insight, 2 (21) e96034. doi: 10.1172/jci.insight.96034

Macrophage-derived oncostatin M contributes to human and mouse neurogenic heterotopic ossifications

2017

Journal Article

CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair

Batoon, Lena, Millard, Susan Marie, Wullschleger, Martin Eduar, Preda, Corina, Wu, Andy Chiu-Ku, Kaur, Simranpreet, Tseng, Hsu-Wen, Hume, David Arthur, Levesque, Jean-Pierre, Raggatt, Liza Jane and Pettit, Allison Robyn (2017). CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair. Biomaterials, 196, 51-66. doi: 10.1016/j.biomaterials.2017.10.033

CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair

2017

Journal Article

Characterization of normal murine carpal bone development prompts re-evaluation of pathological osteolysis as the cause of human carpal-tarsal osteolysis disorders

Lazarus, Syndia, Tseng, Hsu-Wen, Lawrence, Felicity, Woodruff, Maria Ann, Duncan, Emma Letitia and Pettit, Allison Robyn (2017). Characterization of normal murine carpal bone development prompts re-evaluation of pathological osteolysis as the cause of human carpal-tarsal osteolysis disorders. American Journal of Pathology, 187 (9), 1923-1934. doi: 10.1016/j.ajpath.2017.05.007

Characterization of normal murine carpal bone development prompts re-evaluation of pathological osteolysis as the cause of human carpal-tarsal osteolysis disorders

2017

Journal Article

Osteomacs and bone regeneration

Batoon, Lena, Millard, Susan Marie, Raggatt, Liza Jane and Pettit, Allison Robyn (2017). Osteomacs and bone regeneration. Current Osteoporosis Reports, 15 (4), 385-395. doi: 10.1007/s11914-017-0384-x

Osteomacs and bone regeneration