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2003

Journal Article

APC mutation and tumour budding in colorectal cancer

Jass, JR, Barker, M, Fraser, L, Walsh, MD, Whitehall, VLJ, Gabrielli, B, Young, J and Leggett, BA (2003). APC mutation and tumour budding in colorectal cancer. Journal of Clinical Pathology, 56 (1), 69-73. doi: 10.1136/jcp.56.1.69

APC mutation and tumour budding in colorectal cancer

2003

Journal Article

Tumor cell-specific cytotoxicity by targeting cell cycle checkpoints

Warrener, R, Beamish, H, Burgess, A, Waterhouse, NJ, Giles, N, Fairlie, DP and Gabrielli, B (2003). Tumor cell-specific cytotoxicity by targeting cell cycle checkpoints. Faseb Journal, 17 (9), 1550-1570. doi: 10.1096/fj.02-1003fje

Tumor cell-specific cytotoxicity by targeting cell cycle checkpoints

2003

Journal Article

Mechanism of mitosis-specific activation of MEK1

Harding, A., Giles, N., Burgess, A., Hancock, J. F. and Gabrielli, B. G. (2003). Mechanism of mitosis-specific activation of MEK1. Journal of Biological Chemistry, 278 (19), 16747-16754. doi: 10.1074/jbc.M301015200

Mechanism of mitosis-specific activation of MEK1

2003

Journal Article

14-3-3 acts as an intramolecular bridge to regulate cdc25B localization and activity

Giles, N., Forrest, A. and Gabrielli, B. (2003). 14-3-3 acts as an intramolecular bridge to regulate cdc25B localization and activity. Journal of Biological Chemistry, 278 (31), 28580-28587. doi: 10.1074/jbc.M304027200

14-3-3 acts as an intramolecular bridge to regulate cdc25B localization and activity

2002

Journal Article

Identifying molecular targets mediating the anticancer activity of histone deacetylase inhibitors: A work in progress

Gabrielli, B. G., Johnstone, R. W. and Saunders, N. A. (2002). Identifying molecular targets mediating the anticancer activity of histone deacetylase inhibitors: A work in progress. Current Cancer Drug Targets, 2 (4), 337-353. doi: 10.2174/1568009023333818

Identifying molecular targets mediating the anticancer activity of histone deacetylase inhibitors: A work in progress

2002

Journal Article

Introduction: Molecular and biomechanical basis of osteoarthritis

Pavey, Sandra, Russell, Terry and Gabrielli, Brian (2002). Introduction: Molecular and biomechanical basis of osteoarthritis. Cellular and Molecular Life Sciences, 59 (1), 3-4. doi: 10.1007/s00018-002-8399-5

Introduction: Molecular and biomechanical basis of osteoarthritis

2002

Journal Article

A histone deacetylase inhibitor, azelaic bishydroxamic acid, shows cytotoxicity on Epstein-Barr virus-transformed B-cell lines - A potential therapy for posttransplant lymphoproliferative disease

Sculley, T. B., Buck, M., Gabrielli, B., Parsons, P. G. and Krauer, K. G. (2002). A histone deacetylase inhibitor, azelaic bishydroxamic acid, shows cytotoxicity on Epstein-Barr virus-transformed B-cell lines - A potential therapy for posttransplant lymphoproliferative disease. Transplantation, 73 (2), 271-279. doi: 10.1097/00007890-200201270-00021

A histone deacetylase inhibitor, azelaic bishydroxamic acid, shows cytotoxicity on Epstein-Barr virus-transformed B-cell lines - A potential therapy for posttransplant lymphoproliferative disease

2002

Journal Article

Tumor-selective toxicity of histone deacetylase inhibitors is due to their targeting cell cycle checkpoint points

Gabrielli, B, Warrener, R, Beamish, H, Burgess, A and Waterhouse, N (2002). Tumor-selective toxicity of histone deacetylase inhibitors is due to their targeting cell cycle checkpoint points. European Journal of Cancer, 38, S95-S95.

Tumor-selective toxicity of histone deacetylase inhibitors is due to their targeting cell cycle checkpoint points

2002

Journal Article

Loss of p16 expression is associated with histological features of melanoma invasion

Pavey, S. J., Cummings, M. C., Whiteman, D. C., Castellano, M., Walsh, M. D., Gabrielli, B. G., Green, A. and Hayward, N. K. (2002). Loss of p16 expression is associated with histological features of melanoma invasion. Melanoma Research, 12 (6), 539-547. doi: 10.1097/01.cmr.0000043154.28051.9f

Loss of p16 expression is associated with histological features of melanoma invasion

2002

Journal Article

alpha-melanocyte stimulating hormone potentiates p16/CDKN2A expression in human skin after ultraviolet irradiation

Pavey, S. and Gabrielli, B. (2002). alpha-melanocyte stimulating hormone potentiates p16/CDKN2A expression in human skin after ultraviolet irradiation. Cancer Research, 62 (3), 875-880.

alpha-melanocyte stimulating hormone potentiates p16/CDKN2A expression in human skin after ultraviolet irradiation

2001

Journal Article

G2 phase cell cycle arrest in human skin following UV irradiation

Pavey, Sandra, Russell, Terry and Gabrielli, Brian (2001). G2 phase cell cycle arrest in human skin following UV irradiation. Oncogene, 20 (43), 6103-6110. doi: 10.1038/sj.onc.1204707

G2 phase cell cycle arrest in human skin following UV irradiation

2001

Journal Article

Cdc25B activity is regulated by 14-3-3

Forrest, A. and Gabrielli, B. (2001). Cdc25B activity is regulated by 14-3-3. Oncogene, 20 (32), 4393-4401. doi: 10.1038/sj.onc.1204574

Cdc25B activity is regulated by 14-3-3

2001

Journal Article

Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATR

Goldstone, S., Pavey, S., Forrest, A., Sinnamon, J. and Gabrielli, B. (2001). Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATR. Oncogene, 20 (8), 921-932. doi: 10.1038/sj.onc.1204177

Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATR

2001

Journal Article

Up-regulation of p21(WAF1)/(CIP1) by histone deacetylase inhibitors reduces their cytotoxicity

Burgess, A. J., Pavey, S., Warrener, R., Hunter, L. J. K., Piva, T. J., Musgrove, E. A., Saunders, N., Parsons, P. G. and Gabrielli, B. G. (2001). Up-regulation of p21(WAF1)/(CIP1) by histone deacetylase inhibitors reduces their cytotoxicity. Molecular Pharmacology, 60 (4), 828-837.

Up-regulation of p21(WAF1)/(CIP1) by histone deacetylase inhibitors reduces their cytotoxicity

2001

Journal Article

Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblasts

Brinkmann, Hannah, Dahler, Alison L., Popa, Claudia, Serewko, Magdalena M., Parsons, Peter G., Gabrielli, Brian G., Burgess, Andrew J. and Saunders, Nicholas A. (2001). Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblasts. Journal of Biological Chemistry, 276 (25), 22491-22499. doi: 10.1074/jbc.M100206200

Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblasts

2000

Journal Article

Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells

Qiu, Ling, Burgess, Andrew, Fairlie, David P., Leonard, Helen, Parsons, Peter G. and Gabrielli, Brian G. (2000). Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells. Molecular Biology of the Cell, 11 (6), 2069-2083. doi: 10.1091/mbc.11.6.2069

Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells

2000

Journal Article

Regulation of CDC25B phosphatases subcellular localization

Davezac, N, Baldin, V, Gabrielli, B, Forrest, A, Theis-Febvre, N, Yashida, M and Ducommun, B (2000). Regulation of CDC25B phosphatases subcellular localization. Oncogene, 19 (18), 2179-2185. doi: 10.1038/sj.onc.1203545

Regulation of CDC25B phosphatases subcellular localization

2000

Journal Article

Centrosomal and cytoplasmic Cdc2/Cyclin B1 activation precedes nuclear mitotic events

De Souza, C. P. C., Ellem, K. A. O. and Gabrielli, B. G. (2000). Centrosomal and cytoplasmic Cdc2/Cyclin B1 activation precedes nuclear mitotic events. Experimental Cell Research, 257 (1), 11-21. doi: 10.1006/excr.2000.4872

Centrosomal and cytoplasmic Cdc2/Cyclin B1 activation precedes nuclear mitotic events

1999

Journal Article

Multiple splicing variants of cdc25B regulate G2/M progression

Forrest, A. R. R., McCormack, A. K., DeSouza, C. P. C., Sinnamon, J. M., Tonks, I. D., Hayward, N. K., Ellem, K. A. O. and Gabrielli, B. G. (1999). Multiple splicing variants of cdc25B regulate G2/M progression. Biochemical and Biophysical Research Communications, 260 (2), 510-515. doi: 10.1006/bbrc.1999.0870

Multiple splicing variants of cdc25B regulate G2/M progression

1999

Journal Article

Functional reassessment of p16 variants using a transfection-based assay

Walker, GJ, Gabrielli, BG, Castellano, M and Hayward, NK (1999). Functional reassessment of p16 variants using a transfection-based assay. International Journal of Cancer, 82 (2), 305-312. doi: 10.1002/(SICI)1097-0215(19990719)82:23.0.CO;2-Z

Functional reassessment of p16 variants using a transfection-based assay