2003 Journal Article APC mutation and tumour budding in colorectal cancerJass, JR, Barker, M, Fraser, L, Walsh, MD, Whitehall, VLJ, Gabrielli, B, Young, J and Leggett, BA (2003). APC mutation and tumour budding in colorectal cancer. Journal of Clinical Pathology, 56 (1), 69-73. doi: 10.1136/jcp.56.1.69 |
2003 Journal Article Tumor cell-specific cytotoxicity by targeting cell cycle checkpointsWarrener, R, Beamish, H, Burgess, A, Waterhouse, NJ, Giles, N, Fairlie, DP and Gabrielli, B (2003). Tumor cell-specific cytotoxicity by targeting cell cycle checkpoints. Faseb Journal, 17 (9), 1550-1570. doi: 10.1096/fj.02-1003fje |
2003 Journal Article Mechanism of mitosis-specific activation of MEK1Harding, A., Giles, N., Burgess, A., Hancock, J. F. and Gabrielli, B. G. (2003). Mechanism of mitosis-specific activation of MEK1. Journal of Biological Chemistry, 278 (19), 16747-16754. doi: 10.1074/jbc.M301015200 |
2003 Journal Article 14-3-3 acts as an intramolecular bridge to regulate cdc25B localization and activityGiles, N., Forrest, A. and Gabrielli, B. (2003). 14-3-3 acts as an intramolecular bridge to regulate cdc25B localization and activity. Journal of Biological Chemistry, 278 (31), 28580-28587. doi: 10.1074/jbc.M304027200 |
2002 Journal Article Identifying molecular targets mediating the anticancer activity of histone deacetylase inhibitors: A work in progressGabrielli, B. G., Johnstone, R. W. and Saunders, N. A. (2002). Identifying molecular targets mediating the anticancer activity of histone deacetylase inhibitors: A work in progress. Current Cancer Drug Targets, 2 (4), 337-353. doi: 10.2174/1568009023333818 |
2002 Journal Article Introduction: Molecular and biomechanical basis of osteoarthritisPavey, Sandra, Russell, Terry and Gabrielli, Brian (2002). Introduction: Molecular and biomechanical basis of osteoarthritis. Cellular and Molecular Life Sciences, 59 (1), 3-4. doi: 10.1007/s00018-002-8399-5 |
2002 Journal Article A histone deacetylase inhibitor, azelaic bishydroxamic acid, shows cytotoxicity on Epstein-Barr virus-transformed B-cell lines - A potential therapy for posttransplant lymphoproliferative diseaseSculley, T. B., Buck, M., Gabrielli, B., Parsons, P. G. and Krauer, K. G. (2002). A histone deacetylase inhibitor, azelaic bishydroxamic acid, shows cytotoxicity on Epstein-Barr virus-transformed B-cell lines - A potential therapy for posttransplant lymphoproliferative disease. Transplantation, 73 (2), 271-279. doi: 10.1097/00007890-200201270-00021 |
2002 Journal Article Tumor-selective toxicity of histone deacetylase inhibitors is due to their targeting cell cycle checkpoint pointsGabrielli, B, Warrener, R, Beamish, H, Burgess, A and Waterhouse, N (2002). Tumor-selective toxicity of histone deacetylase inhibitors is due to their targeting cell cycle checkpoint points. European Journal of Cancer, 38, S95-S95. |
2002 Journal Article Loss of p16 expression is associated with histological features of melanoma invasionPavey, S. J., Cummings, M. C., Whiteman, D. C., Castellano, M., Walsh, M. D., Gabrielli, B. G., Green, A. and Hayward, N. K. (2002). Loss of p16 expression is associated with histological features of melanoma invasion. Melanoma Research, 12 (6), 539-547. doi: 10.1097/01.cmr.0000043154.28051.9f |
2002 Journal Article alpha-melanocyte stimulating hormone potentiates p16/CDKN2A expression in human skin after ultraviolet irradiationPavey, S. and Gabrielli, B. (2002). alpha-melanocyte stimulating hormone potentiates p16/CDKN2A expression in human skin after ultraviolet irradiation. Cancer Research, 62 (3), 875-880. |
2001 Journal Article G2 phase cell cycle arrest in human skin following UV irradiationPavey, Sandra, Russell, Terry and Gabrielli, Brian (2001). G2 phase cell cycle arrest in human skin following UV irradiation. Oncogene, 20 (43), 6103-6110. doi: 10.1038/sj.onc.1204707 |
2001 Journal Article Cdc25B activity is regulated by 14-3-3Forrest, A. and Gabrielli, B. (2001). Cdc25B activity is regulated by 14-3-3. Oncogene, 20 (32), 4393-4401. doi: 10.1038/sj.onc.1204574 |
2001 Journal Article Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATRGoldstone, S., Pavey, S., Forrest, A., Sinnamon, J. and Gabrielli, B. (2001). Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATR. Oncogene, 20 (8), 921-932. doi: 10.1038/sj.onc.1204177 |
2001 Journal Article Up-regulation of p21(WAF1)/(CIP1) by histone deacetylase inhibitors reduces their cytotoxicityBurgess, A. J., Pavey, S., Warrener, R., Hunter, L. J. K., Piva, T. J., Musgrove, E. A., Saunders, N., Parsons, P. G. and Gabrielli, B. G. (2001). Up-regulation of p21(WAF1)/(CIP1) by histone deacetylase inhibitors reduces their cytotoxicity. Molecular Pharmacology, 60 (4), 828-837. |
2001 Journal Article Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblastsBrinkmann, Hannah, Dahler, Alison L., Popa, Claudia, Serewko, Magdalena M., Parsons, Peter G., Gabrielli, Brian G., Burgess, Andrew J. and Saunders, Nicholas A. (2001). Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblasts. Journal of Biological Chemistry, 276 (25), 22491-22499. doi: 10.1074/jbc.M100206200 |
2000 Journal Article Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cellsQiu, Ling, Burgess, Andrew, Fairlie, David P., Leonard, Helen, Parsons, Peter G. and Gabrielli, Brian G. (2000). Histone deacetylase inhibitors trigger a G2 checkpoint in normal cells that is defective in tumor cells. Molecular Biology of the Cell, 11 (6), 2069-2083. doi: 10.1091/mbc.11.6.2069 |
2000 Journal Article Regulation of CDC25B phosphatases subcellular localizationDavezac, N, Baldin, V, Gabrielli, B, Forrest, A, Theis-Febvre, N, Yashida, M and Ducommun, B (2000). Regulation of CDC25B phosphatases subcellular localization. Oncogene, 19 (18), 2179-2185. doi: 10.1038/sj.onc.1203545 |
2000 Journal Article Centrosomal and cytoplasmic Cdc2/Cyclin B1 activation precedes nuclear mitotic eventsDe Souza, C. P. C., Ellem, K. A. O. and Gabrielli, B. G. (2000). Centrosomal and cytoplasmic Cdc2/Cyclin B1 activation precedes nuclear mitotic events. Experimental Cell Research, 257 (1), 11-21. doi: 10.1006/excr.2000.4872 |
1999 Journal Article Multiple splicing variants of cdc25B regulate G2/M progressionForrest, A. R. R., McCormack, A. K., DeSouza, C. P. C., Sinnamon, J. M., Tonks, I. D., Hayward, N. K., Ellem, K. A. O. and Gabrielli, B. G. (1999). Multiple splicing variants of cdc25B regulate G2/M progression. Biochemical and Biophysical Research Communications, 260 (2), 510-515. doi: 10.1006/bbrc.1999.0870 |
1999 Journal Article Functional reassessment of p16 variants using a transfection-based assayWalker, GJ, Gabrielli, BG, Castellano, M and Hayward, NK (1999). Functional reassessment of p16 variants using a transfection-based assay. International Journal of Cancer, 82 (2), 305-312. doi: 10.1002/(SICI)1097-0215(19990719)82:23.0.CO;2-Z |