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2022 Journal Article CSF1R as a therapeutic target in bone diseases: obvious but not so simpleHume, David A., Batoon, Lena, Sehgal, Anuj, Keshvari, Sahar and Irvine, Katharine M. (2022). CSF1R as a therapeutic target in bone diseases: obvious but not so simple. Current Osteoporosis Reports, 20 (6), 516-531. doi: 10.1007/s11914-022-00757-4 |
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2022 Journal Article Validation of the new 2021 EASL algorithm for the noninvasive diagnosis of advanced fibrosis in NAFLDCanivet, Clémence M., Costentin, Charlotte, Irvine, Katharina M., Delamarre, Adèle, Lannes, Adrien, Sturm, Nathalie, Oberti, Frederic, Patel, Preya J., Decaens, Thomas, Irles-Depé, Marie, Fouchard, Isabelle, Hermabessière, Paul, Roux, Marine, Barthelon, Justine, Calès, Paul, Powell, Elizabeth E., de Ledinghen, Victor and Boursier, Jérôme (2022). Validation of the new 2021 EASL algorithm for the noninvasive diagnosis of advanced fibrosis in NAFLD. Hepatology, 77 (3), n/a-n/a. doi: 10.1002/hep.32665 |
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2022 Journal Article Low accuracy of FIB-4 test to identify people with diabetes at low risk of advanced fibrosisGracen, Lucy, Hayward, Kelly L., Irvine, Katharine M., Valery, Patricia C. and Powell, Elizabeth E. (2022). Low accuracy of FIB-4 test to identify people with diabetes at low risk of advanced fibrosis. Journal of Hepatology, 77 (4), 1219-1221. doi: 10.1016/j.jhep.2022.06.016 |
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2022 Journal Article Epidemiology of ascites fluid infections in patients with cirrhosis in Queensland, Australia from 2008 to 2017: a population-based studyRatnasekera, Isanka U., Johnson, Amy, Powell, Elizabeth E., Henderson, Andrew, Irvine, Katharine M. and Valery, Patricia C. (2022). Epidemiology of ascites fluid infections in patients with cirrhosis in Queensland, Australia from 2008 to 2017: a population-based study. Medicine, 101 (20) 00010, e29217. doi: 10.1097/MD.0000000000029217 |
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2022 Journal Article Patient‐oriented medication education intervention has long‐term benefits for people with decompensated cirrhosisHayward, Kelly L., Bansal, Vikas, Valery, Patricia C., Irvine, Katharine M., Wright, Penny L., Tallis, Caroline J., Stuart, Katherine A., Cottrell, W. Neil, Martin, Jennifer H. and Powell, Elizabeth E. (2022). Patient‐oriented medication education intervention has long‐term benefits for people with decompensated cirrhosis. Hepatology Communications, 6 (11), 3281-3282. doi: 10.1002/hep4.1999 |
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2022 Journal Article A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signallingStables, Jennifer, Green, Emma K., Sehgal, Anuj, Patkar, Omkar L., Keshvari, Sahar, Taylor, Isis, Ashcroft, Maisie E., Grabert, Kathleen, Wollscheid-Lengeling, Evi, Szymkowiak, Stefan, McColl, Barry W., Adamson, Antony, Humphreys, Neil E., Mueller, Werner, Starobova, Hana, Vetter, Irina, Shabestari, Sepideh Kiani, Blurton-Jones, Matthew M., Summers, Kim M., Irvine, Katharine M., Pridans, Clare and Hume, David A. (2022). A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling. Development, 149 (8) dev200237. doi: 10.1242/dev.200237 |
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2022 Journal Article Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophagesTran, Thao Thanh, Mathmann, Carmen D., Gatica-Andrades, Marcela, Rollo, Rachel F., Oelker, Melanie, Ljungberg, Johanna K., Nguyen, Tam T. K., Zamoshnikova, Alina, Kummari, Lalith K., Wyer, Orry J. K., Irvine, Katharine M., Melo-Bolívar, Javier, Gross, Annette, Brown, Darren, Mak, Jeffrey Y. W., Fairlie, David P., Hansford, Karl A., Cooper, Matthew A., Giri, Rabina, Schreiber, Veronika, Joseph, Shannon R., Simpson, Fiona, Barnett, Timothy C., Johansson, Jörgen, Dankers, Wendy, Harris, James, Wells, Timothy J., Kapetanovic, Ronan, Sweet, Matthew J. ... Blumenthal, Antje (2022). Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages. PLoS Pathogens, 18 (1) e1010166, e1010166. doi: 10.1371/journal.ppat.1010166 |
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2022 Journal Article Depressive symptoms in non-alcoholic fatty liver disease are identified by perturbed lipid and lipoprotein metabolismRadford-Smith, Daniel E., Patel, Preya J., Irvine, Katharine M., Russell, Anthony, Siskind, Dan, Anthony, Daniel C., Powell, Elizabeth E. and Probert, Fay (2022). Depressive symptoms in non-alcoholic fatty liver disease are identified by perturbed lipid and lipoprotein metabolism. PLoS ONE, 17 (1) e0261555, e0261555. doi: 10.1371/journal.pone.0261555 |
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2022 Journal Article ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosisNalkurthi, Christina, Schroder, Wayne A., Melino, Michelle, Irvine, Katharine M., Nyuydzefe, Melanie, Chen, Wei, Liu, Jing, Teng, Michele WL., Hill, Geoffrey R., Bertolino, Patrick, Blazar, Bruce R., Miller, Gregory C., Clouston, Andrew D., Zanin-Zhorov, Alexandra and MacDonald, Kelli PA. (2022). ROCK2 inhibition attenuates profibrogenic immune cell function to reverse thioacetamide-induced liver fibrosis. JHEP Reports, 4 (1) 100386, 1-14. doi: 10.1016/j.jhepr.2021.100386 |
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2022 Journal Article Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver diseaseKeshvari, Sahar, Genz, Berit, Teakle, Ngari, Caruso, Melanie, Cestari, Michelle F., Patkar, Omkar L., Tse, Brian W. C., Sokolowski, Kamil A., Ebersbach, Hilmar, Jascur, Julia, MacDonald, Kelli P. A., Miller, Gregory, Ramm, Grant A., Pettit, Allison R., Clouston, Andrew D., Powell, Elizabeth E., Hume, David A. and Irvine, Katharine M. (2022). Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease. Disease Models and Mechanisms, 15 (4) dmm049387, 1-15. doi: 10.1242/dmm.049387 |
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2021 Journal Article Bacteraemia, sepsis and antibiotic resistance in Australian patients with cirrhosis: a population-based studyJohnson, Amy L., Ratnasekera, Isanka U., Irvine, Katharine M., Henderson, Andrew, Powell, Elizabeth E. and Valery, Patricia C. (2021). Bacteraemia, sepsis and antibiotic resistance in Australian patients with cirrhosis: a population-based study. BMJ Open Gastroenterology, 8 (1) e000695, e000695. doi: 10.1136/bmjgast-2021-000695 |
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2021 Journal Article A binge high sucrose diet provokes systemic and cerebral inflammation in rats without inducing obesityPatkar, Omkar L., Mohamed, Abdalla Z., Narayanan, Ashwin, Mardon, Karine, Cowin, Gary, Bhalla, Rajiv, Stimson, Damion H. R., Kassiou, Michael, Beecher, Kate, Belmer, Arnauld, Alvarez Cooper, Ignatius, Morgan, Michael, Hume, David A., Irvine, Katharine M., Bartlett, Selena E., Nasrallah, Fatima and Cumming, Paul (2021). A binge high sucrose diet provokes systemic and cerebral inflammation in rats without inducing obesity. Scientific Reports, 11 (1) 11252, 11252. doi: 10.1038/s41598-021-90817-z |
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2021 Journal Article Serum matrix metalloproteinase 7 (MMP7) is a biomarker of fibrosis in patients with non-alcoholic fatty liver diseaseIrvine, Katharine M., Okano, Satomi, Patel, Preya J., Horsfall, Leigh U., Williams, Suzanne, Russell, Anthony and Powell, Elizabeth E. (2021). Serum matrix metalloproteinase 7 (MMP7) is a biomarker of fibrosis in patients with non-alcoholic fatty liver disease. Scientific Reports, 11 (1) 2858, 1-8. doi: 10.1038/s41598-021-82315-z |
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2021 Journal Article Medication discrepancies and regimen complexity in decompensated cirrhosis: implications for medication safetyHayward, Kelly L., Valery, Patricia C., Patel, Preya J., Li, Catherine, Horsfall, Leigh U., Wright, Penny L., Tallis, Caroline J., Stuart, Katherine A., David, Michael, Irvine, Katharine M., Cottrell, Neil, Martin, Jennifer H. and Powell, Elizabeth E. (2021). Medication discrepancies and regimen complexity in decompensated cirrhosis: implications for medication safety. Pharmaceuticals, 14 (12) 1207, 1207. doi: 10.3390/ph14121207 |
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2021 Journal Article Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissuesMillard, Susan M., Heng, Ostyn, Opperman, Khatora S., Sehgal, Anuj, Irvine, Katharine M., Kaur, Simranpreet, Sandrock, Cheyenne J., Wu, Andy C., Magor, Graham W., Batoon, Lena, Perkins, Andrew C., Noll, Jacqueline E., Zannettino, Andrew C.W., Sester, David P., Levesque, Jean-Pierre, Hume, David A., Raggatt, Liza J., Summers, Kim M. and Pettit, Allison R. (2021). Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues. Cell Reports, 37 (8) 110058, 110058. doi: 10.1016/j.celrep.2021.110058 |
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2021 Journal Article Predicting liver‐related outcomes in people with nonalcoholic fatty liver disease: the prognostic value of noninvasive fibrosis testsJohnson, Amy L., Hayward, Kelly L., Patel, Preya, Horsfall, Leigh U., Cheah, Alvin Ee Zhiun, Irvine, Katharine M., Russell, Anthony W., Stuart, Katherine A., Williams, Sue, Hartel, Gunter, Valery, Patricia C. and Powell, Elizabeth E. (2021). Predicting liver‐related outcomes in people with nonalcoholic fatty liver disease: the prognostic value of noninvasive fibrosis tests. Hepatology Communications, 6 (4), 728-739. doi: 10.1002/hep4.1852 |
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2021 Journal Article Osteal macrophages support osteoclast‐mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse modelBatoon, Lena, Millard, Susan M., Raggatt, Liza J., Wu, Andy C., Kaur, Simranpreet, Sun, Lucas W.H., Williams, Kyle, Sandrock, Cheyenne, Ng, Pei Ying, Irvine, Katharine M., Bartnikowski, Michal, Glatt, Vaida, Pavlos, Nathan J. and Pettit, Allison R. (2021). Osteal macrophages support osteoclast‐mediated resorption and contribute to bone pathology in a postmenopausal osteoporosis mouse model. Journal of Bone and Mineral Research, 36 (11), 2214-2228. doi: 10.1002/jbmr.4413 |
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2021 Journal Article Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repairSehgal, Anuj, Irvine, Katharine M. and Hume, David A. (2021). Functions of macrophage colony-stimulating factor (CSF1) in development, homeostasis, and tissue repair. Seminars in Immunology, 54 101509, 101509. doi: 10.1016/j.smim.2021.101509 |
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2021 Journal Article Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bonesBatoon, Lena, Millard, Susan M., Raggatt, Liza J., Sandrock, Cheyenne, Pickering, Edmund, Williams, Kyle, Sun, Lucas W.H., Wu, Andy C., Irvine, Katharine M., Pivonka, Peter, Glatt, Vaida, Wullschleger, Martin E., Hume, David A. and Pettit, Allison R. (2021). Treatment with a long-acting chimeric CSF1 molecule enhances fracture healing of healthy and osteoporotic bones. Biomaterials, 275 120936, 120936. doi: 10.1016/j.biomaterials.2021.120936 |
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2021 Journal Article Towards collaborative management of nonalcoholic fatty liver disease ( TCM‐NAFLD ): a ‘real‐world’ pathway for fibrosis risk assessment in primary careHayward, Kelly L., McKillen, Benjamin J., Horsfall, Leigh U., McIvor, Carolyn, Liew, Katerina, Sexton, Jo, Johnson, Amy L., Irvine, Katharine M., Valery, Patricia C., McPhail, Steven M., Britton, Laurence J., Rosenberg, William, Weate, Ingrid, Williams, Sue and Powell, Elizabeth E. (2021). Towards collaborative management of nonalcoholic fatty liver disease ( TCM‐NAFLD ): a ‘real‐world’ pathway for fibrosis risk assessment in primary care. Internal Medicine Journal, 52 (10) imj.15422, 1749-1758. doi: 10.1111/imj.15422 |
