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2016 Journal Article CRIg-expressing peritoneal macrophages are associated with disease severity in patients with cirrhosis and ascitesIrvine, Katharine M., Xuan Banh, Gadd, Victoria L., Wojcik, Kyle K., Ariffin, Juliana K., Jose, Sara, Lukowski, Samuel, Baillie, Gregory J., Sweet, Matthew J. and Powell, Elizabeth E. (2016). CRIg-expressing peritoneal macrophages are associated with disease severity in patients with cirrhosis and ascites. JCI Insight, 1 (8) e86914, e86914. doi: 10.1172/jci.insight.86914 |
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2016 Journal Article Patterns of service utilisation within Australian hepatology clinics: high prevalence of advanced liver diseaseEl-Atem, N. A., Wojcik, K., Horsfall, L., Irvine, K. M., Johnson, T., McPhail, S. M. and Powell, E. E. (2016). Patterns of service utilisation within Australian hepatology clinics: high prevalence of advanced liver disease. Internal Medicine Journal, 46 (4), 420-426. doi: 10.1111/imj.13008 |
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2016 Journal Article Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury modelMelino, Michelle, Gadd, Victoria L., Alexander, Kylie A., Beattie, Lynette, Lineburg, Katie E., Martinez, Michelle, Teal, Bianca, Le Texier, Laetitia, Irvine, Katharine M., Miller, Gregory C., Boyle, Glen M., Hill, Geoffrey R., Clouston, Andrew D., Powel, Elizabeth E. and MacDonald, Kelli P. A. (2016). Spatiotemporal characterization of the cellular and molecular contributors to liver fibrosis in a murine hepatotoxic-injury model. American Journal of Pathology, 186 (3), 524-538. doi: 10.1016/j.ajpath.2015.10.029 |
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2016 Journal Article Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophagesKapetanovic, Ronan, Bokil, Nilesh J., Achard, Maud E. S., Ong, Cheryl-lynn Y, Peters, Kate M., Stocks, Claudia J., Phan, Minh-Duy, Monteleone, Mercedes, Schroder, Kate, Irvine, Katharine M., Saunders, Bernadette M., Walker, Mark J., Stacey, Katryn J., McEwan, Alastair G., Schembri, Mark A. and Sweet, Matthew J. (2016). Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages. The FASEB Journal, 30 (5), 1901-1912. doi: 10.1096/fj.201500061 |
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2015 Journal Article Can paracetamol (acetaminophen) be administered to patients with liver impairment?Hayward, Kelly L., Powell, Elizabeth E., Irvine, Katharine M. and Martin, Jennifer H. (2015). Can paracetamol (acetaminophen) be administered to patients with liver impairment?. British Journal of Clinical Pharmacology, 81 (2), 210-222. doi: 10.1111/bcp.12802 |
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2015 Journal Article Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injuryIrvine, Katharine M., Clouston, Andrew D., Gadd, Victoria L., Miller, Gregory C., Wong, Weng-Yew, Melino, Michelle, Maradana, Muralidhara Rao, MacDonald, Kelli, Lang, Richard A., Sweet, Matthew J., Blumenthal, Antje and Powell, Elizabeth E. (2015). Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury. Fibrogenesis and Tissue Repair, 8 (19) 19, 19. doi: 10.1186/s13069-015-0036-7 |
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2015 Journal Article The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver diseaseIrvine, Katharine M., Wockner, Leesa F., Shanker, Mihir, Fagan, Kevin J., Horsfall, Leigh U., Fletcher, Linda M., Ungerer, Jacobus P. J., Pretorius, Carel J., Miller, Gregory C., Clouston, Andrew D., Lampe, Guy and Powell, Elizabeth E. (2015). The Enhanced liver fibrosis score is associated with clinical outcomes and disease progression in patients with chronic liver disease. Liver International, 36 (3), 370-377. doi: 10.1111/liv.12896 |
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2015 Journal Article Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetesPang, Dimeng, Irvine, Katharine M., Mehdi, Ahmed M., Thomas, Helen E., Harris, Mark, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2015). Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes. Clinical and Translational Immunology, 4 (8) e41, e41.1-e41.9. doi: 10.1038/cti.2015.17 |
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2015 Journal Article Response to ELF cut-off points: aetiology is also a relevant factorPowell, Elizabeth E., Irvine, Katharine M., Fagan, Kevin J., Ballard, Emma and O'Rourke, Peter (2015). Response to ELF cut-off points: aetiology is also a relevant factor. Liver International, 35 (7), 1921-1921. doi: 10.1111/liv.12822 |
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2015 Journal Article ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activityFagan, Kevin J., Pretorius, Carel J., Horsfall, Leigh U., Irvine, Katharine M., Wilgen, Urs, Choi, Kihoon, Fletcher, Linda M., Tate, Jill, Melino, Michelle, Nusrat, Sharmin, Miller, Gregory C., Clouston, Andrew D., Ballard, Emma, O'Rourke, Peter, Lampe, Guy, Ungerer, Jacobus P. J. and Powell, Elizabeth E. (2015). ELF score ≥9.8 indicates advanced hepatic fibrosis and is influenced by age, steatosis and histological activity. Liver International, 35 (6), 1673-1681. doi: 10.1111/liv.12760 |
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2015 Journal Article Ascites bacterial burden and immune cell profile are associated with poor clinical outcomes in the absence of overt infectionFagan, Kevin J., Rogers, Geraint B., Melino, Michelle, Arthur, Dionne M., Costello, Mary-Ellen, Morrison, Mark, Powell, Elizabeth E. and Irvine, Katharine M. (2015). Ascites bacterial burden and immune cell profile are associated with poor clinical outcomes in the absence of overt infection. PLoS One, 10 (3) e0120642, e0120642. doi: 10.1371/journal.pone.0120642 |
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2014 Journal Article Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migrationIrvine, Katharine M., Skoien, Richard, Bokil, Nilesh J., Melino, Michelle, Thomas, Gethin P., Loo, Dorothy, Gabrielli, Brian, Hill, Michelle M., Sweet, Matthew J., Clouston, Andrew D. and Powell, Elizabeth E. (2014). Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration. World Journal of Gastroenterology, 20 (47), 17851-17862. doi: 10.3748/wjg.v20.i47.17851 |
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2014 Journal Article Burden of decompensated cirrhosis and ascites on hospital services in a tertiary care facility: time for change?Fagan, K. J., Zhao, Eileen Y., Horsfall, L. U., Ruffin, Brittany J., Kruger, Mark S., McPhail, S. M., O'Rourke, Peter, Ballard, Emma, Irvine, K. M. and Powell, E. E. (2014). Burden of decompensated cirrhosis and ascites on hospital services in a tertiary care facility: time for change?. Internal Medicine Journal, 44 (9), 865-872. doi: 10.1111/imj.12491 |
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2014 Journal Article Diagnostic sensitivity of carbohydrate deficient transferrin in heavy drinkersFagan K.J., Irvine K.M., McWhinney B.C., Fletcher L.M., Horsfall L.U., Johnson L., O'Rourke P., Martin J., Scott I., Pretorius C.J., Ungerer J.P.J. and Powell E.E. (2014). Diagnostic sensitivity of carbohydrate deficient transferrin in heavy drinkers. BMC Gastroenterology, 14 (1) 97, 1-6. doi: 10.1186/1471-230X-14-97 |
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2014 Journal Article The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver diseaseGadd, Victoria L., Skoien, Richard, Powell, Elizabeth E., Fagan, Kevin J., Winterford, Clay, Horsfall, Leigh, Irvine, Katharine and Clouston, Andrew D. (2014). The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease. Hepatology, 59 (4), 1393-1405. doi: 10.1002/hep.26937 |
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2014 Journal Article Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4Yu, C.-H., Nguyen, T.T.K., Irvine, K.M., Sweet, M.J., Frazer, I.H. and Blumenthal, A. (2014). Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4. European Journal of Immunology, 44 (5), 1480-1490. doi: 10.1002/eji.201343959 |
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2014 Journal Article New paradigms in the histopathology of NAFLDClouston, Andrew D., Gadd, Victoria L., Irvine, Katharine M. and Powell, Elizabeth E. (2014). New paradigms in the histopathology of NAFLD. Current Hepatitis Reports, 13 (2), 81-87. doi: 10.1007/s11901-014-0214-x |
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2013 Journal Article Assessment of alcohol histories obtained from patients with liver disease: opportunities to improve early interventionFagan, K. J., Irvine, K. M., Kumar, S., Bates, A., Horsfall, L. U., Feeney, G. F. and Powell, E. E. (2013). Assessment of alcohol histories obtained from patients with liver disease: opportunities to improve early intervention. Internal Medicine Journal, 43 (10), 1096-1102. doi: 10.1111/imj.12229 |
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2013 Journal Article BMI But Not Stage or Etiology of Nonalcoholic Liver Disease Affects the Diagnostic Utility of Carbohydrate-Deficient TransferrinFagan, Kevin J., Irvine, Katharine M., McWhinney, Brett C., Fletcher, Linda M., Horsfall, Leigh U., Johnson, Lambro A., Clouston, Andrew D., Jonsson, Julie R., O'Rourke, Peter, Martin, Jennifer, Pretorius, Carel J., Ungerer, Jacobus P. J. and Powell, Elizabeth E. (2013). BMI But Not Stage or Etiology of Nonalcoholic Liver Disease Affects the Diagnostic Utility of Carbohydrate-Deficient Transferrin. Alcoholism Clinical and Experimental Research, 37 (10), 1771-1778. doi: 10.1111/acer.12143 |
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2013 Journal Article Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophagesShakespear, Melanie R., Hohenhaus, Daniel M., Kelly, Greg M., Kamal, Nabilah A., Gupta, Praveer, Labzin, Larisa I., Schroder, Kate, Garceau, Valerie, Barbero, Sheila, Iyer, Abishek, Hume, David A., Reid, Robert C., Irvine, Katharine M., Fairlie, David P. and Sweet, Matthew J. (2013). Histone deacetylase 7 promotes Toll-like Receptor 4-dependent pro-inflammatory gene expression in macrophages. Journal of Biological Chemistry, 288 (35), 25362-25374. doi: 10.1074/jbc.M113.496281 |
