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2023 Conference Publication The interplay of IL-23, probiotic and pathobiont bacteria in the pathogenesis of ileitis and spondyloarthritis in the SKG mouse modelBergot, Anne-Sophie, Cai, Benjamin, Giri, Rabina, Cameron, Amy, Duggan, Emily, Lim, Kai, Rehaume, Linda, Morrison, Mark, Begun, Jakob and Thomas, Ranjeny (2023). The interplay of IL-23, probiotic and pathobiont bacteria in the pathogenesis of ileitis and spondyloarthritis in the SKG mouse model. 2023 Australian Rheumatology Association (ARA) 63rd Annual Scientific Meeting, Hobart, TAS, Australia, 6–9 May 2023. Hoboken, NJ, United States: Wiley. |
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2023 Conference Publication Withdrawal versus continuation of thiopurine in vedolizumab-treated patients with Ulcerative Colitis (VIEWS): a multi-centre randomised controlled trialPudipeddi, A., Paramsothy, S., Kariyawasam, V., Paramsothy, R., Ghaly, S., Haifer, C., An, Y. K., Begun, J., Connor, S., Corte, C., Ward, M., De Cruz, P., Fung, C., Redmond, D. and Leong, R. W. (2023). Withdrawal versus continuation of thiopurine in vedolizumab-treated patients with Ulcerative Colitis (VIEWS): a multi-centre randomised controlled trial. OXFORD: OXFORD UNIV PRESS. |
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2023 Conference Publication Post-ustekinumab induction IL12, IL23, and ustekinumab levels are associated with clinical response in a multi-centre prospective cohort study of Crohn's disease patients: results from the AURORA Study including ANZIBDC CohortAn, Y. K., Lindsay, N., Allan, N., Khoo, E., Fernandes, R., Amiss, A., Pham, H., Wong, K. F., Ooi, S. Y., Thin, L., Lightowler, D., Connor, S. J., Williams, A. J., De Cruz, P., Suen, C. Li Wai, Kariyawasam, V., Mitrev, N., Ghaly, S., Andrews, J. M., Christensen, B., Sparrow, M. P., White, L. S., Bryant, R. V., Ding, N., Leong, R., Van Langenberg, D., Seltenreich, H., Subramaniam, K., Radford-Smith, G. and Begun, J. (2023). Post-ustekinumab induction IL12, IL23, and ustekinumab levels are associated with clinical response in a multi-centre prospective cohort study of Crohn's disease patients: results from the AURORA Study including ANZIBDC Cohort. 18th Congress of ECCO, Copenhagen, Denmark, 1-4 March 2023. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjac190.0793 |
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2023 Conference Publication Reduction of bowel wall thickness and doppler signals as early as 36 hours predicts corticosteroid response in a multi-centre prospective cohort of Acute Severe Ulcerative Colitis: USUC Study including the GENIUS cohortAn, Y. K., Fernandes, R., Lindsay, N., Khoo, E., Pham, H., Wong, K. F., Thin, L., Goodsall, T., Bryant, R. V., Wright, E., Smith, R., Friedman, A., Begun, J. and Gastroenterology Network of Intestinal Ultrasound (GENIUS) (2023). Reduction of bowel wall thickness and doppler signals as early as 36 hours predicts corticosteroid response in a multi-centre prospective cohort of Acute Severe Ulcerative Colitis: USUC Study including the GENIUS cohort. 18th Congress of ECCO, Copenhagen, Denmark, 1-4 March 2023. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjac190.0744 |
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2023 Conference Publication Enhancing the efficacy of cannabidiol using protein nanoparticles to treat inflammatory bowel diseaseMoniruzzaman, M., Rewatkar, P., Begun, J. and Popat, A. (2023). Enhancing the efficacy of cannabidiol using protein nanoparticles to treat inflammatory bowel disease. 18th Congress of ECCO, Copenhagen, Denmark, 1-4 March 2023. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjac190.0167 |
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2023 Conference Publication Withdrawal versus continuation of thiopurine in vedolizumab-treated patients with Ulcerative Colitis (VIEWS): a multi-centre randomised controlled trialPudipeddi, A., Paramsothy, S., Kariyawasam, V., Paramsothy, R., Ghaly, S., Haifer, C., An, Y. K., Begun, J., Connor, S., Corte, C., Ward, M., De Cruz, P., Fung, C., Redmond, D. and Leong, R. W. (2023). Withdrawal versus continuation of thiopurine in vedolizumab-treated patients with Ulcerative Colitis (VIEWS): a multi-centre randomised controlled trial. 18th Congress of ECCO, Copenhagen, Denmark, 1-4 March 2023. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjac190.0543 |
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2022 Conference Publication Efficacy and Safety of Upadacitinib Maintenance Therapy in Patients With Moderately to Severely Active Crohn’s Disease: U-ENDURE Phase 3 ResultsPanes, Julian, Loftus, Edward, Lacerda, Ana, Peyrin-Biroulet, Laurent, D’Haens, Geert, Panaccione, Remo, Reinisch, Walter, Louis, Edouard, Chen, Minhu, Nakase, Hiroshi, Begun, Jakob, Boland, Brigid, Liu, Jianzhong, Dubcenco, Elena, Mohamed, Mohamed-Eslam, Feng, Tian and Colombel, Jean-Frederic (2022). Efficacy and Safety of Upadacitinib Maintenance Therapy in Patients With Moderately to Severely Active Crohn’s Disease: U-ENDURE Phase 3 Results. 2022 Advances in Inflammatory Bowel Diseases Annual Meeting, Orlando, FL United States, 5-7 December 2022. Philadelphia, PA United States: Wolters Kluwer. doi: 10.14309/01.ajg.0000897656.25080.34 |
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2022 Conference Publication Post-induction IL-12/23 levels correlate with clinical response and remission after ustekinumab in a multicenter prospective cohort study of patients with Crohn’s disease: Preliminary induction results of the AURORA study, including the Australia New Zealand IBD Consortium CohortAn,Yoon-Kyo, Lindsay, Niamh, Allan, Natalie, Khoo, Emi, Amiss, Anna, Moniruzzaman, Md, Fernandes, Richard, Ooi, Soong-Yuan J., Thin, Lena W.Y., Mstj, Daniel Lightowler, Connor, Susan, Williams, Astrid-Jane, De Cruz, Peter, Suen, Christopher Li Wai, Kariyawasam, Viraj C., Mitrev, Nicola, Ghaly, Simon, Andrews, Jane M., Christensen, Britt, Sparrow, Miles, White, Lauren, Bryant, Robert, Ding, Nik S., Leong, Rupert W., Van Langenberg, Daniel R., Seltenreich, Hans, Subramaniam, Kavitha, Radford-Smith, Graham and Begun, Jakob (2022). Post-induction IL-12/23 levels correlate with clinical response and remission after ustekinumab in a multicenter prospective cohort study of patients with Crohn’s disease: Preliminary induction results of the AURORA study, including the Australia New Zealand IBD Consortium Cohort. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2022, Sydney, NSW Australia, 9–11 September 2022. Richmond, VIC Australia: John Wiley & Sons. doi: 10.1111/jgh.15953 |
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2022 Conference Publication Histological Remission Using A Nancy Index Of 0 Is Associated With Longer Relapse-free Survival Than Histological Activity In Patients With Ulcerative Colitis In Clinical And Endoscopic RemissionPudipeddi, Aviv, Fung, Caroline, Kariyawasam, Viraj, Paramsothy, Ramesh, Ghaly, Simon, Haifer, Craig, An, Yoon, Begun, Jakob, Connor, Susan, Chetwood, John, Paramsothy, Sudarshan and Leong, Rupert (2022). Histological Remission Using A Nancy Index Of 0 Is Associated With Longer Relapse-free Survival Than Histological Activity In Patients With Ulcerative Colitis In Clinical And Endoscopic Remission. International Digestive Disease Forum (IDDF), Hong Kong, China, 2-4 September 2022. London, United Kingdom: BMJ Group. doi: 10.1136/gutjnl-2022-IDDF.207 |
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2022 Conference Publication Ocrelizumab-induced medically refractory fulminant colitis requiring colectomyMalloy, R., Fernandes, R., Begun, J. and An, Y-K (2022). Ocrelizumab-induced medically refractory fulminant colitis requiring colectomy. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) 2022, International Convention Centre Sydney (ICC Sydney), Sydney, NSW, Australia, 9 - 11 September 2022. Richmond, VIC, Australia: John Wiley & Sons. doi: 10.1111/jgh.15953 |
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2021 Conference Publication Higher anti-tumour necrosis factor-alpha drug levels are associated with improved radiological outcomes in patients with perianal fistulising Crohn’s disease: A retrospective multi-centre studyDe Gregorio, M., Lee, T., Krishnaprasad, K., Amos, G., An, Y. K., Bastian-Jordan, M., Begun, J., Borok, N., Brown, D. J. M., Cheung, W., Connor, S., Gerstenmaier, J., Gilbert, L. E., Gilmore, R., Gu, B., Kutaiba, N., Lee, A., Mahy, G., Srinivasan, A., Thin, L., Thompson, A., Welman, C. J., Yong, E. X., De Cruz, P., van Langenberg, D., Sparrow, M. and Ding, N. S. (2021). Higher anti-tumour necrosis factor-alpha drug levels are associated with improved radiological outcomes in patients with perianal fistulising Crohn’s disease: A retrospective multi-centre study. 16th Congress of ECCO, Online, 2-3 & 8-10 July 2021. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjab076.523 |
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2021 Conference Publication So many therapies—So little data: How to choose? Session two summaryBegun, Jakob (2021). So many therapies—So little data: How to choose? Session two summary. Takeda IBD Symposium IBD 2020: Right Therapy, Right Patient, Right Time#Choosing Wisely, Online, 5 September 2020. Richmond, VIC Australia: Wiley-Blackwell. doi: 10.1111/jgh.15450 |
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2020 Conference Publication Curdlan-induced villous permeability, luminal pathobiont translocation to the ileal crypts, ileitis and arthritis are mitigated by clostridia in colonised germ-free SKG miceBergot, Anne-Sophie, Giri, Rabina, Cameron, Amy, Duggan, Emily, Loayza, Jeimy Jimenez, Morrison, Mark, Rehaume, Linda, Begun, Jakob and Thomas, Ranjeny (2020). Curdlan-induced villous permeability, luminal pathobiont translocation to the ileal crypts, ileitis and arthritis are mitigated by clostridia in colonised germ-free SKG mice. Annual Meeting of the American-College-of-Rheumatology (ACR), Virtual, 5-9 November 2020. Hoboken, NJ USA: John Wiley & Sons. |
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2020 Conference Publication Investigating the role of bioactives produced by gut bacteria to modulate immune response in inflammatory bowel diseaseGiri, R., Shamsunnahar, K., Salim, A., Capon, R., Morrison, M., Cuiv, P. O. and Begun, J. (2020). Investigating the role of bioactives produced by gut bacteria to modulate immune response in inflammatory bowel disease. 15th Congress of ECCO, Vienna, Austria, 12-15 February 2020. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjz203.035 |
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2019 Conference Publication Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathologyKoyama, Motoko, Mukhopadhyay, Pamela, Schuster, Iona S., Henden, Andrea S., Hülsdünker, Jan, Varelias, Antiopi, Vetizou, Marie, Kuns, Rachel D., Robb, Renee J., Zhang, Ping, Blazar, Bruce R., Thomas, Ranjeny, Begun, Jakob, Waddell, Nicola, Trinchieri, Giorgio, Zeiser, Robert, Clouston, Andrew D., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2019). Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.69.38 |
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2019 Conference Publication Endoscopic balloon dilatation is safe and has a high success rate in patients with stricturing Crohn's diseaseLim, E., Thai, M., Hendy, P., Alchlaihawi, M., Leong, R., Connor, S., Ng, W., Gu, B., van Langenberg, D., Thin, L., Schulberg, J., Kamm, M., Gilmore, R., Taylor, K., Sallis, O., Andrews, J., Daker, C., Barclay, M., Wark, G., Ghaly, S., Begun, M., Krishnaprasad, K. and Begun, J. (2019). Endoscopic balloon dilatation is safe and has a high success rate in patients with stricturing Crohn's disease. 14th Congress of ECCO, Copenhagen, Denmark, 6-9 March 2019. Oxford, United Kingdom: Oxford University Press. doi: 10.1093/ecco-jcc/jjy222.647 |
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2019 Conference Publication Switching Australian patients with moderate to severe inflammatory bowel disease from originator infliximab to biosimilar Inflectra: Interim results from a multicenter parallel cohort studyHaifer, C., Srinivasan, A., Menon, S., An, Y., Picardo, S., Van Langenberg, D., Begun, J., Ghaly, S. and Thin, L. (2019). Switching Australian patients with moderate to severe inflammatory bowel disease from originator infliximab to biosimilar Inflectra: Interim results from a multicenter parallel cohort study. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide, SA, Australia, 8–10 September 2019. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.14801 |
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2019 Conference Publication Investigating the role of bioactives produced by gut bacteria to modulate immune response in inflammatory bowel diseaseGiri, R., Cuiv, P. O. and Begun, J. (2019). Investigating the role of bioactives produced by gut bacteria to modulate immune response in inflammatory bowel disease. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide, Australia, 8-10 September 2019. Hoboken, NJ, United States: Wiley-Blackwell. doi: 10.1111/jgh.14800 |
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2019 Conference Publication Effectiveness of fecal calprotectin testing to identify patients with organic gastrointestinal diseases: a systematic review and diagnostic meta-analysisAn, Y., Prince, D., Gardiner, F., Linedale, E., Andrews, J., Connor, S. and Begun, J. (2019). Effectiveness of fecal calprotectin testing to identify patients with organic gastrointestinal diseases: a systematic review and diagnostic meta-analysis. Gastroenterological Society of Australia (GESA) Australian Gastroenterology Week (AGW) “The Universe Within”, Adelaide, South Australia, 8-10 September 2019. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/jgh.14803 |
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2019 Conference Publication On the role of inflammation in acute paracetamol injuryAlabbas, Saleh, Movva, Ramya, Begun, Jakob, Florin, Timothy and Oancea, Iulia (2019). On the role of inflammation in acute paracetamol injury. International Liver Congress, Vienna Austria, 10-14 April 2019. Amsterdam, Netherlands: Elsevier. doi: 10.1016/S0618-8278(19)30823-0 |
