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Associate Professor David Muller
Associate Professor

David Muller

Email: 

Overview

Availability

Associate Professor David Muller is:
Available for supervision

Fields of research

Qualifications

  • Bachelor (Honours), The University of Queensland
  • Doctor of Philosophy, The University of Queensland

Works

Search Professor David Muller’s works on UQ eSpace

47 works between 2005 and 2024

1 - 20 of 47 works

2024

Journal Article

Enhancement of cellular immunity following needle-free vaccination of mice with SARS-CoV-2 spike protein

McMillan, Christopher L. D., Wijesundara, Danushka K., Choo, Jovin J. Y., Amarilla, Alberto A., Modhiran, Naphak, Fernando, Germain J. P., Khromykh, Alexander A., Watterson, Daniel, Young, Paul R. and Muller, David A. (2024). Enhancement of cellular immunity following needle-free vaccination of mice with SARS-CoV-2 spike protein. Journal of General Virology, 105 (1) ARTN 001947, 1-6. doi: 10.1099/jgv.0.001947

Enhancement of cellular immunity following needle-free vaccination of mice with SARS-CoV-2 spike protein

2023

Journal Article

Superior efficacy of a skin-applied microprojection device for delivering a novel Zika DNA vaccine

Wijesundara, Danushka K., Yeow, Arthur, McMillan, Christopher L. D., Choo, Jovin J. Y., Todorovic, Aleksandra, Mekonnen, Zelalem A., Masavuli, Makutiro G., Young, Paul R., Gowans, Eric J., Grubor-Bauk, Branka and Muller, David A. (2023). Superior efficacy of a skin-applied microprojection device for delivering a novel Zika DNA vaccine. Molecular Therapy Nucleic Acids, 34 102056. doi: 10.1016/j.omtn.2023.102056

Superior efficacy of a skin-applied microprojection device for delivering a novel Zika DNA vaccine

2023

Journal Article

Elevated BMI reduces the humoral response to SARS‐CoV‐2 infection

Tong, Marcus Z. W., Sng, Julian D. J., Carney, Meagan, Cooper, Lucy, Brown, Samuel, Lineburg, Katie E., Chew, Keng Yih, Collins, Neve, Ignacio, Kirsten, Airey, Megan, Burr, Lucy, Joyce, Briony A., Jayasinghe, Dhilshan, McMillan, Christopher L. D., Muller, David A., Adhikari, Anurag, Gallo, Linda A., Dorey, Emily S., Barrett, Helen L., Gras, Stephanie, Smith, Corey, Good‐Jacobson, Kim and Short, Kirsty R. (2023). Elevated BMI reduces the humoral response to SARS‐CoV‐2 infection. Clinical and Translational Immunology, 12 (12) e1476, 1-13. doi: 10.1002/cti2.1476

Elevated BMI reduces the humoral response to SARS‐CoV‐2 infection

2023

Journal Article

Safety, tolerability, and immunogenicity of measles and rubella vaccine delivered with a high-density microarray patch: results from a randomized, partially double-blinded, placebo-controlled phase I clinical trial

Baker, Ben, Bermingham, Imogen M., Leelasena, Indika, Hickling, Julian, Young, Paul R., Muller, David A. and Forster, Angus H. (2023). Safety, tolerability, and immunogenicity of measles and rubella vaccine delivered with a high-density microarray patch: results from a randomized, partially double-blinded, placebo-controlled phase I clinical trial. Vaccines, 11 (11) 1725, 1-17. doi: 10.3390/vaccines11111725

Safety, tolerability, and immunogenicity of measles and rubella vaccine delivered with a high-density microarray patch: results from a randomized, partially double-blinded, placebo-controlled phase I clinical trial

2023

Journal Article

Microarray patches: scratching the surface of vaccine delivery

Choo, Jovin J. Y., McMillan, Christopher L. D., Young, Paul R. and Muller, David A. (2023). Microarray patches: scratching the surface of vaccine delivery. Expert Review of Vaccines, 22 (1), 937-955. doi: 10.1080/14760584.2023.2270598

Microarray patches: scratching the surface of vaccine delivery

2022

Journal Article

Monoclonal antibodies specific for SARS-CoV-2 spike protein suitable for multiple applications for current variants of concern

Morgan, Mahali S., Yan, Kexin, Le, Thuy T., Johnston, Ryan A., Amarilla, Alberto A., Muller, David A., McMillan, Christopher L. D., Modhiran, Naphak, Watterson, Daniel, Potter, James R., Sng, Julian D. J., Lor, Mary, Paramitha, Devina, Isaacs, Ariel, Khromykh, Alexander A., Hall, Roy A., Suhrbier, Andreas, Rawle, Daniel J. and Hobson-Peters, Jody (2022). Monoclonal antibodies specific for SARS-CoV-2 spike protein suitable for multiple applications for current variants of concern. Viruses, 15 (1) 139, 1-18. doi: 10.3390/v15010139

Monoclonal antibodies specific for SARS-CoV-2 spike protein suitable for multiple applications for current variants of concern

2022

Journal Article

Skin-patch delivered subunit vaccine induces broadly neutralising antibodies against SARS-CoV-2 variants of concern

McMillan, Christopher L.D., Amarilla, Alberto A., Modhiran, Naphak, Choo, Jovin J.Y., Azuar, Armira, Honeyman, Kate E., Khromykh, Alexander A., Young, Paul R., Watterson, Daniel and Muller, David A. (2022). Skin-patch delivered subunit vaccine induces broadly neutralising antibodies against SARS-CoV-2 variants of concern. Vaccine, 40 (34), 4929-4932. doi: 10.1016/j.vaccine.2022.07.013

Skin-patch delivered subunit vaccine induces broadly neutralising antibodies against SARS-CoV-2 variants of concern

2022

Journal Article

Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variants

Isaacs, Ariel, Amarilla, Alberto A., Aguado, Julio, Modhiran, Naphak, Albornoz, Eduardo A., Baradar, Alireza A., McMillan, Christopher L. D., Choo, Jovin J. Y., Idris, Adi, Supramaniam, Aroon, McMillan, Nigel A. J., Muller, David A., Young, Paul R., Woodruff, Trent M., Wolvetang, Ernst J., Chappell, Keith J. and Watterson, Daniel (2022). Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variants. Frontiers in Immunology, 13 926262, 926262. doi: 10.3389/fimmu.2022.926262

Nucleocapsid specific diagnostics for the detection of divergent SARS-CoV-2 variants

2022

Journal Article

Absence of anti-RBD antibodies in SARS-CoV-2 infected or naive individuals prior to vaccination with CoronaVac leads to short protection of only four months duration

Oliveira, Camille F. de, Neto, Walter F. F., Silva, Carla P. da, Ribeiro, Ana Claudia S., Martins, Lívia C., Sousa, Alana W. de, Freitas, Maria N. O., Chiang, Jannifer O., Silva, Franko A., Santos, Eder B. dos, Medeiros, Daniele B. A., Pinheiro, Gleiciane S., Brandão, Gleiciane F., Carvalho, Valéria L., Azevedo, Raimunda S. S., Vasconcelos, Pedro F. C., Costa, Igor B., Costa, Iran B., Santos, Mirleide C. dos, Soares, Luana S., Bedran, Rayssa L. S., Ferreira, James L., Amarilla, Alberto A., Modhiran, Naphak, McMillan, Christopher L. D., Freney, Morgan E., Muller, David A., Watterson, Daniel, Casseb, Lívia M. N. and Henriques, Daniele F. (2022). Absence of anti-RBD antibodies in SARS-CoV-2 infected or naive individuals prior to vaccination with CoronaVac leads to short protection of only four months duration. Vaccines, 10 (5) 690, 690. doi: 10.3390/vaccines10050690

Absence of anti-RBD antibodies in SARS-CoV-2 infected or naive individuals prior to vaccination with CoronaVac leads to short protection of only four months duration

2022

Journal Article

Local response and barrier recovery in elderly skin following the application of high-density microarray patches

Iredahl, Fredrik, Muller, David A., Togö, Totte, Jonasson, Hanna, Baker, Ben, Anderson, Chris D. and Henricson, Joakim (2022). Local response and barrier recovery in elderly skin following the application of high-density microarray patches. Vaccines, 10 (4) 583, 583. doi: 10.3390/vaccines10040583

Local response and barrier recovery in elderly skin following the application of high-density microarray patches

2022

Journal Article

Dermal delivery of a SARS-CoV-2 subunit vaccine induces immunogenicity against variants of concern

McMillan, Christopher L. D., Azuar, Armira, Choo, Jovin J. Y., Modhiran, Naphak, Amarilla, Alberto A., Isaacs, Ariel, Honeyman, Kate E., Cheung, Stacey T. M., Liang, Benjamin, Wurm, Maria J., Pino, Paco, Kint, Joeri, Fernando, Germain J. P., Landsberg, Michael J., Khromykh, Alexander A., Hobson-Peters, Jody, Watterson, Daniel, Young, Paul R. and Muller, David A. (2022). Dermal delivery of a SARS-CoV-2 subunit vaccine induces immunogenicity against variants of concern. Vaccines, 10 (4) 578, 578. doi: 10.3390/vaccines10040578

Dermal delivery of a SARS-CoV-2 subunit vaccine induces immunogenicity against variants of concern

2022

Journal Article

Micropuncture closure following high density microarray patch application in healthy subjects

Henricson, Joakim, Muller, David A., Baker, S. Ben, Iredahl, Fredrik, Togö, Totte and Anderson, Chris D. (2022). Micropuncture closure following high density microarray patch application in healthy subjects. Skin Research and Technology, 28 (2), 305-310. doi: 10.1111/srt.13131

Micropuncture closure following high density microarray patch application in healthy subjects

2021

Journal Article

Developing a stabilizing formulation of a live chimeric dengue virus vaccine dry coated on a high-density microarray patch

Choo, Jovin J. Y., McMillan, Christopher L. D., Fernando, Germain J. P., Hall, Roy A., Young, Paul R., Hobson-Peters, Jody and Muller, David A. (2021). Developing a stabilizing formulation of a live chimeric dengue virus vaccine dry coated on a high-density microarray patch. Vaccines, 9 (11) 1301, 1301. doi: 10.3390/vaccines9111301

Developing a stabilizing formulation of a live chimeric dengue virus vaccine dry coated on a high-density microarray patch

2021

Journal Article

Complete protection by a single-dose skin patch–delivered SARS-CoV-2 spike vaccine

McMillan, Christopher L. D., Choo, Jovin J. Y., Idris, Adi, Supramaniam, Aroon, Modhiran, Naphak, Amarilla, Alberto A., Isaacs, Ariel, Cheung, Stacey T. M., Liang, Benjamin, Bielefeldt-Ohmann, Helle, Azuar, Armira, Acharya, Dhruba, Kelly, Gabrielle, Fernando, Germain J. P., Landsberg, Michael J., Khromykh, Alexander A., Watterson, Daniel, Young, Paul R., McMillan, Nigel A. J. and Muller, David A. (2021). Complete protection by a single-dose skin patch–delivered SARS-CoV-2 spike vaccine. Science Advances, 7 (44) eabj8065, eabj8065. doi: 10.1126/sciadv.abj8065

Complete protection by a single-dose skin patch–delivered SARS-CoV-2 spike vaccine

2021

Journal Article

Implications of dengue virus maturation on vaccine induced humoral immunity in mice

Scott, Connor A. P., Amarilla, Alberto A., Bibby, Summa, Newton, Natalee D., Hall, Roy A., Hobson-Peters, Jody, Muller, David A., Chappell, Keith J., Young, Paul R., Modhiran, Naphak and Watterson, Daniel (2021). Implications of dengue virus maturation on vaccine induced humoral immunity in mice. Viruses, 13 (9) 1843, 1843. doi: 10.3390/v13091843

Implications of dengue virus maturation on vaccine induced humoral immunity in mice

2021

Journal Article

A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses

Amarilla, Alberto A., Sng, Julian D. J., Parry, Rhys, Deerain, Joshua M., Potter, James R., Setoh, Yin Xiang, Rawle, Daniel J., Le, Thuy T., Modhiran, Naphak, Wang, Xiaohui, Peng, Nias Y. G., Torres, Francisco J., Pyke, Alyssa, Harrison, Jessica J., Freney, Morgan E., Liang, Benjamin, McMillan, Christopher L. D., Cheung, Stacey T. M., Guevara, Darwin J Da Costa, Hardy, Joshua M., Bettington, Mark, Muller, David A., Coulibaly, Fasséli, Moore, Frederick, Hall, Roy A., Young, Paul R., Mackenzie, Jason M., Hobson-Peters, Jody, Suhrbier, Andreas ... Khromykh, Alexander A. (2021). A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses. Nature Communications, 12 (1) 3431, 3431. doi: 10.1038/s41467-021-23779-5

A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses

2021

Journal Article

A chimeric dengue virus vaccine candidate delivered by high density microarray patches protects against infection in mice

Choo, Jovin J. Y., Vet, Laura J., McMillan, Christopher L. D., Harrison, Jessica J., Scott, Connor A. P., Depelsenaire, Alexandra C. I., Fernando, Germain J. P., Watterson, Daniel, Hall, Roy A., Young, Paul R., Hobson-Peters, Jody and Muller, David A. (2021). A chimeric dengue virus vaccine candidate delivered by high density microarray patches protects against infection in mice. npj Vaccines, 6 (1) 66, 66. doi: 10.1038/s41541-021-00328-1

A chimeric dengue virus vaccine candidate delivered by high density microarray patches protects against infection in mice

2021

Journal Article

A broadly protective antibody that targets the flavivirus NS1 protein

Modhiran, Naphak, Song, Hao, Liu, Lidong, Bletchly, Cheryl, Brillault, Lou, Amarilla, Alberto A., Xu, Xiaoying, Qi, Jianxun, Chai, Yan, Cheung, Stacey T. M., Traves, Renee, Setoh, Yin Xiang, Bibby, Summa, Scott, Connor A. P., Freney, Morgan E., Newton, Natalee D., Khromykh, Alexander A., Chappell, Keith J., Muller, David A., Stacey, Katryn J., Landsberg, Michael J., Shi, Yi, Gao, George F., Young, Paul R. and Watterson, Daniel (2021). A broadly protective antibody that targets the flavivirus NS1 protein. Science, 371 (6525), 190-194. doi: 10.1126/science.abb9425

A broadly protective antibody that targets the flavivirus NS1 protein

2020

Journal Article

Innate local response and tissue recovery following application of high density microarray patches to human skin

Muller, David A., Henricson, Joakim, Baker, S. Ben, Togö, Totte, Jayashi Flores, Cesar M., Lemaire, Pierre A., Forster, Angus and Anderson, Chris D. (2020). Innate local response and tissue recovery following application of high density microarray patches to human skin. Scientific Reports, 10 (1) 18468, 18468. doi: 10.1038/s41598-020-75169-4

Innate local response and tissue recovery following application of high density microarray patches to human skin

2019

Journal Article

Efficient delivery of dengue virus subunit vaccines to the skin by microprojection arrays

Muller, David A., Depelsenaire, Alexandra C. I., Shannon, Ashleigh E., Watterson, Daniel, Corrie, Simon R., Owens, Nick S., Agyei-Yeboah, Christiana, Cheung, Stacey T. M., Zhang, Jin, Fernando, Germain J. P., Kendall, Mark A. F. and Young, Paul R. (2019). Efficient delivery of dengue virus subunit vaccines to the skin by microprojection arrays. Vaccines, 7 (4) 189, 189. doi: 10.3390/vaccines7040189

Efficient delivery of dengue virus subunit vaccines to the skin by microprojection arrays

Funding

Current funding

  • 2024 - 2027
    Disassembled/reassembled extracellular vesicles (DR-EVs) - a new class of nanoparticles for disease treatment (NHMRC Ideas Grant administered by Griffith University)
    Griffith University
    Open grant
  • 2023 - 2025
    Development of monovalent type 1 and trivalent poliovirus VLP patches
    Global Polio Eradication Initiative
    Open grant
  • 2023 - 2028
    Building the next mRNA vaccines and therapies
    MRFF - National Critical Infrastructure Initiative
    Open grant
  • 2023 - 2025
    Phase 2 clinical study for a next-generation, needle free COVID-19 vaccine CRC-P administered by Vaxxas Pty Ltd)
    Vaxxas Pty Ltd
    Open grant
  • 2023 - 2025
    CRACing the role of the Flavivirus NS1 protein
    NHMRC IDEAS Grants
    Open grant
  • 2022 - 2024
    Evaluation of a breast cancer DNA vaccine
    UniQuest Pty Ltd
    Open grant

Past funding

  • 2020 - 2023
    Enhancing COVID-19 vaccination and pandemic preparedness via Nanopatch skin delivery
    Advance Queensland Industry Research Fellowships
    Open grant
  • 2020 - 2022
    Preclinical evaluation of Nanopatch-delivered poliovirus virus-like particles, and to explore co-formulation with dmLT
    Global Polio Eradication Initiative
    Open grant
  • 2020 - 2023
    Chimeric insect-specific viruses as novel vaccines for mosquito-borne diseases
    NHMRC Development Grant
    Open grant
  • 2018 - 2021
    Needle free delivery of dengue and Zika vaccines to the skin
    NHMRC Development Grant
    Open grant
  • 2016 - 2019
    Dengue virus NS1 protein as a mediator of pathology
    NHMRC Project Grant
    Open grant
  • 2014 - 2018
    Novel tetravalent dengue virus subunit vaccines delivered by Nanopatch
    Queensland Government Accelerate Fellowships
    Open grant
  • 2014 - 2016
    Nanopatch and delivery device for Polio vaccine
    UniQuest Pty Ltd
    Open grant

Supervision

Availability

Associate Professor David Muller is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Supervision history

Current supervision

  • Doctor Philosophy

    Development and optimisation of bioprocesses for scale-up manufacture of chimeric antigens for flavivirus vaccines and diagnostics

    Associate Advisor

    Other advisors: Associate Professor Jody Peters

Completed supervision

Media

Enquiries

For media enquiries about Associate Professor David Muller's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au