Dr

Andy Kuo

Email: 
Phone: 
+61 7 334 69365

Background

Dr Andy Kuo is a Senior Research Officer and Centre Manager at the Centre for Integrated Preclinical Drug Development (CIPDD), a Tier 2 Infrastructure Centre located in the School of Biomedical Sciences at UQ. With expertise in preclinical translational research, in the last ten years Dr Kuo in the role of Study Director, has managed the conduct of numerous R&D contract-funded and collaborative research grant-funded studies that are/have been undertaken in accordance with the requirements of CIPDD’s electronic Quality Management System (eQMS), which is rare in Australia.

To date he has successfully conducted/managed over 60 research projects, conducted in accordance with the requirements of CIPDD’s eQMS framework. His extensive experience encompasses experimental procedures and the management of preclinical studies, particularly in the areas of animal model development/validation, pharmacodynamic readouts, pharmacokinetics, and toxicology.

Despite the demands of working in an NCRIS (National Collaborative Research Infrastructure Strategy)-funded National Centre that is a key partner in Therapeutic Innovation Australia’s (TIA) Small Molecule Therapeutics Capability focused on IP-sensitive research, he has sustained a robust publication record, with 32 publications and 2 book chapters. Additionally, he has submitted 46 commercial-in-confidence study reports to industry and academic collaborators contributing significantly to the field of novel therapeutics innovation.

Availability

Dr Andy Kuo is:
Available for supervision

Search Professor Andy Kuo’s works on UQ eSpace

38 works between 2008 and 2024
All (38) Journal Article (34) Book Chapter (1) Conference Publication (2) Other Outputs (1)

21 - 38 of 38 works

2018

Journal Article

Comparative analgesic efficacy of pregabalin administered according to either a prevention protocol or an intervention protocol in rats with cisplatin-induced peripheral neuropathy

Han, Felicity Y., Kuo, Andy, Nicholson, Janet R., Corradinni, Laura and Smith, Maree T. (2018). Comparative analgesic efficacy of pregabalin administered according to either a prevention protocol or an intervention protocol in rats with cisplatin-induced peripheral neuropathy. Clinical and Experimental Pharmacology and Physiology, 45 (10), 1067-1075. doi: 10.1111/1440-1681.12971

Comparative analgesic efficacy of pregabalin administered according to either a prevention protocol or an intervention protocol in rats with cisplatin-induced peripheral neuropathy

2018

Journal Article

Corrigendum to: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere (Angewandte Chemie International Edition, (2016), 55, 11, (3580-3585), 10.1002/anie.201510675)

Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2018). Corrigendum to: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere (Angewandte Chemie International Edition, (2016), 55, 11, (3580-3585), 10.1002/anie.201510675). Angewandte Chemie - International Edition, 57 (28), 8359-8359. doi: 10.1002/anie.201711161

Corrigendum to: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere (Angewandte Chemie International Edition, (2016), 55, 11, (3580-3585), 10.1002/anie.201510675)

2018

Journal Article

Chronic low back pain: a mini-review on pharmacological management and pathophysiological insights from clinical and pre-clinical data

Park, Thomas S. W., Kuo, Andy and Smith, Maree T. (2018). Chronic low back pain: a mini-review on pharmacological management and pathophysiological insights from clinical and pre-clinical data. Inflammopharmacology, 26 (4), 1-18. doi: 10.1007/s10787-018-0493-x

Chronic low back pain: a mini-review on pharmacological management and pathophysiological insights from clinical and pre-clinical data

2018

Journal Article

The somatostatin receptor-4 agonist J-2156 alleviates mechanical hypersensitivity in a rat model of breast cancer induced bone pain

Shenoy, Priyank A., Kuo, Andy, Khan, Nemat, Gorham, Louise, Nicholson, Janet, Corradini, Laura, Vetter, Irina and Smith, Maree T. (2018). The somatostatin receptor-4 agonist J-2156 alleviates mechanical hypersensitivity in a rat model of breast cancer induced bone pain. Frontiers in Pharmacology, 9 (MAY) 495, 495. doi: 10.3389/fphar.2018.00495

The somatostatin receptor-4 agonist J-2156 alleviates mechanical hypersensitivity in a rat model of breast cancer induced bone pain

2018

Journal Article

Synthesis and Biological Evaluation of Fentanyl Analogues Modified at Phenyl Groups with Alkyls

Qin, Yajuan, Ni, Luofan, Shi, Jiawei, Zhu, Zhiying, Shi, Saijian, Lam, Ai-Leen, Magiera, Julia, Sekar, Sunderajhan, Kuo, Andy, Smith, Maree T. and Li, Tingyou (2018). Synthesis and Biological Evaluation of Fentanyl Analogues Modified at Phenyl Groups with Alkyls. ACS Chemical Neuroscience, 10 (1) acschemneuro.8b00363, 201-208. doi: 10.1021/acschemneuro.8b00363

Synthesis and Biological Evaluation of Fentanyl Analogues Modified at Phenyl Groups with Alkyls

2017

Journal Article

Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depression

Imam, Mohammad Zafar, Kuo, Andy, Ghassabian, Sussan and Smith, Maree T. (2017). Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depression. Neuropharmacology, 131, 238-255. doi: 10.1016/j.neuropharm.2017.12.032

Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depression

2017

Journal Article

Pharmacological inhibition of the NLRP3 inflammasome as a potential target for multiple sclerosis induced central neuropathic pain

Khan, Nemat, Kuo, Andy, Brockman, David A, Cooper, Matthew A and Smith, Maree T (2017). Pharmacological inhibition of the NLRP3 inflammasome as a potential target for multiple sclerosis induced central neuropathic pain. Inflammopharmacology, 26 (1), 77-86. doi: 10.1007/s10787-017-0401-9

Pharmacological inhibition of the NLRP3 inflammasome as a potential target for multiple sclerosis induced central neuropathic pain

2017

Journal Article

Establishment and characterization of a novel rat model of mechanical low back pain using behavioral, pharmacologic and histologic methods

Muralidharan, Arjun, Park, Thomas S. W., Mackie, John T., Gimenez, Luiz G. S., Kuo, Andy, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2017). Establishment and characterization of a novel rat model of mechanical low back pain using behavioral, pharmacologic and histologic methods. Frontiers in Pharmacology, 8 493, 493.1-493.12. doi: 10.3389/fphar.2017.00493

Establishment and characterization of a novel rat model of mechanical low back pain using behavioral, pharmacologic and histologic methods

2017

Journal Article

Optimization and in vivo profiling of a refined rat model of Walker 256 breast cancer cell-induced bone pain using behavioral, radiological, histological, immunohistochemical and pharmacological methods

Shenoy, Priyank, Kuo, Andy, Vetter, Irina and Smith, Maree T. (2017). Optimization and in vivo profiling of a refined rat model of Walker 256 breast cancer cell-induced bone pain using behavioral, radiological, histological, immunohistochemical and pharmacological methods. Frontiers in Pharmacology, 8 (JUL) 442, 442. doi: 10.3389/fphar.2017.00442

Optimization and in vivo profiling of a refined rat model of Walker 256 breast cancer cell-induced bone pain using behavioral, radiological, histological, immunohistochemical and pharmacological methods

2016

Journal Article

The Walker 256 breast cancer cell-induced bone pain model in rats

Shenoy, Priyank A., Kuo, Andy, Vetter, Irina and Smith, Maree T. (2016). The Walker 256 breast cancer cell-induced bone pain model in rats. Frontiers in Pharmacology, 7 (AUG) 286, 286. doi: 10.3389/fphar.2016.00286

The Walker 256 breast cancer cell-induced bone pain model in rats

2016

Journal Article

Comparison of burrowing and stimuli-evoked pain behaviors as end-points in rat models of inflammatory pain and peripheral neuropathic pain

Muralidharan, Arjun, Kuo, Andy, Jacob, Meera, Lourdesamy, Jacintha S., Melo Sores Pinho De Carvalho, Lara, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2016). Comparison of burrowing and stimuli-evoked pain behaviors as end-points in rat models of inflammatory pain and peripheral neuropathic pain. Frontiers in Behavioral Neuroscience, 10 (88) 88, 88. doi: 10.3389/fnbeh.2016.00088

Comparison of burrowing and stimuli-evoked pain behaviors as end-points in rat models of inflammatory pain and peripheral neuropathic pain

2016

Journal Article

Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere

Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2016). Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere. Angewandte Chemie International Edition, 55 (11), 8359-8359. doi: 10.1002/anie.201681161

Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere

2016

Journal Article

Validating Eaton's hypothesis: cubane as a benzene bioisostere

Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2016). Validating Eaton's hypothesis: cubane as a benzene bioisostere. Angewandte Chemie (International Edition), 55 (11), 3580-3585. doi: 10.1002/anie.201510675

Validating Eaton's hypothesis: cubane as a benzene bioisostere

2014

Journal Article

Theoretical and practical applications of the intracerebroventricular route for CSF sampling and drug administration in CNS drug discovery research: a mini review

Kuo, Andy and Smith, Maree T. (2014). Theoretical and practical applications of the intracerebroventricular route for CSF sampling and drug administration in CNS drug discovery research: a mini review. Journal of Neuroscience Methods, 233, 166-171. doi: 10.1016/j.jneumeth.2014.06.006

Theoretical and practical applications of the intracerebroventricular route for CSF sampling and drug administration in CNS drug discovery research: a mini review

2014

Journal Article

In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile

Kuo, A., Wyse, B. D., Meutermans, W. and Smith, M. T. (2014). In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile. British Journal of Pharmacology, Accepted Article (2), 1-48. doi: 10.1111/bph.12696

In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile

2012

Other Outputs

Systematic evaluation of in vitro and in vivo opioid profiling

Kuo, Andy (2012). Systematic evaluation of in vitro and in vivo opioid profiling. PhD Thesis, School of Pharmacy, The University of Queensland.

Systematic evaluation of in vitro and in vivo opioid profiling

2008

Conference Publication

Comparative profiles of the antinociceptive and constipating effects of single intracerebroventricular (i.c.v.) bolus doses of morphine, morphine-6-glucuronide and fentanyl in rats Kuo A, Hemstapat K, Wyse BD, Smith MT

Hemstapat, K., Kuo, A., Smith, M.T. and Wyse, B.D. (2008). Comparative profiles of the antinociceptive and constipating effects of single intracerebroventricular (i.c.v.) bolus doses of morphine, morphine-6-glucuronide and fentanyl in rats Kuo A, Hemstapat K, Wyse BD, Smith MT. 4th Scientific Meeting of the Australian Health and Medical Research Congress, Brisbane, Australia, 16 - 21 November, 2008.

Comparative profiles of the antinociceptive and constipating effects of single intracerebroventricular (i.c.v.) bolus doses of morphine, morphine-6-glucuronide and fentanyl in rats Kuo A, Hemstapat K, Wyse BD, Smith MT

2008

Conference Publication

Comparative profiles of the antinociceptive and constipating effects of single intracerebroventricular (i.c.v.) bolus doses of morphine and oxycodone in rats

Kuo, A., Hemstapat, K., Wyse, B. D., South, S. M. and Smith, M. T. (2008). Comparative profiles of the antinociceptive and constipating effects of single intracerebroventricular (i.c.v.) bolus doses of morphine and oxycodone in rats. 12th World Congress on Pain, Glasgow, UK, 17-22 August 2008.

Comparative profiles of the antinociceptive and constipating effects of single intracerebroventricular (i.c.v.) bolus doses of morphine and oxycodone in rats

Current funding

  • 2022 - 2024
    Assess the clinical disease-modifying effects of one peptide test item given twice-weekly for 3 weeks relative to sham control and vehicle in the relapsing-remitting experimental autoimmune encephalom
    Argenica Therapeutics Limited
    Open grant

Past funding

  • 2016
    Novel Pain therapeutics discovery: Probing molecular mechanisms
    NHMRC Equipment Grant
    Open grant

Availability

Dr Andy Kuo is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

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