Overview
Background
Dr Andy Kuo is a Senior Research Fellow and Assistant Director at the Centre for Integrated Preclinical Drug Development (CIPDD), a Tier 2 Infrastructure Centre located in the School of Biomedical Sciences at UQ. With expertise in preclinical translational research, in the last ten years Dr Kuo in the role of Study Director, has managed the conduct of numerous R&D contract-funded and collaborative research grant-funded studies that are/have been undertaken in accordance with the requirements of CIPDD’s electronic Quality Management System (eQMS), which is rare in Australia.
To date he has successfully conducted/managed over 60 research projects, conducted in accordance with the requirements of CIPDD’s eQMS framework. His extensive experience encompasses experimental procedures and the management of preclinical studies, particularly in the areas of animal model development/validation, pharmacodynamic readouts, pharmacokinetics, and toxicology.
Despite the demands of working in an NCRIS (National Collaborative Research Infrastructure Strategy)-funded National Centre that is a key partner in Therapeutic Innovation Australia’s (TIA) Small Molecule Therapeutics Capability focused on IP-sensitive research, he has sustained a robust publication record, with 32 publications and 2 book chapters. Additionally, he has submitted 46 commercial-in-confidence study reports to industry and academic collaborators contributing significantly to the field of novel therapeutics innovation.
Availability
- Dr Andy Kuo is:
- Available for supervision
Works
Search Professor Andy Kuo’s works on UQ eSpace
2020
Journal Article
Countering opioid-induced respiratory depression by non-opioids that are respiratory stimulants
Imam, Mohammad Zafar, Kuo, Andy and Smith, Maree T. (2020). Countering opioid-induced respiratory depression by non-opioids that are respiratory stimulants. F1000Research, 9 91, 91. doi: 10.12688/f1000research.21738.1
2019
Journal Article
Transcriptomic characterisation of the optimised rat model of Walker 256 breast cancer cell-induced bone pain
Shenoy, Priyank A., Kuo, Andy, Leparc, German, Hildebrandt, Tobias, Rust, Werner, Nicholson, Janet R., Corradini, Laura, Vetter, Irina and Smith, Maree T. (2019). Transcriptomic characterisation of the optimised rat model of Walker 256 breast cancer cell-induced bone pain. Clinical and Experimental Pharmacology and Physiology, 46 (12) 1440-1681.13165, 1201-1215. doi: 10.1111/1440-1681.13165
2019
Journal Article
J-2156, a somatostatin receptor type 4 agonist, alleviates mechanical hyperalgesia in a rat model of chronic low back pain
Park, Thomas S.W., Khan, Nemat, Kuo, Andy, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2019). J-2156, a somatostatin receptor type 4 agonist, alleviates mechanical hyperalgesia in a rat model of chronic low back pain. Biomedicine and Pharmacotherapy, 117 109056, 109056. doi: 10.1016/j.biopha.2019.109056
2019
Journal Article
Establishment and characterisation of a stavudine (d4T)-induced rat model of antiretroviral toxic neuropathy (ATN) using behavioural and pharmacological methods
Kuo, Andy, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2019). Establishment and characterisation of a stavudine (d4T)-induced rat model of antiretroviral toxic neuropathy (ATN) using behavioural and pharmacological methods. Inflammopharmacology, 27 (2), 387-396. doi: 10.1007/s10787-018-00551-8
2019
Journal Article
Cyclooctatetraene: a bioactive cubane paradigm complement
Xing, Hui, Houston, Sevan D., Chen, Xuejie, Ghassabian, Sussan, Fahrenhorst-Jones, Tyler, Kuo, Andy, Murray, Cody-Ellen P., Conn, Kyna-Anne, Jaeschke, Kara N., Jin, Da-Yun, Pasay, Cielo, Bernhardt, Paul V., Burns, Jed M., Tsanaktsidis, John, Savage, G. Paul, Boyle, Glen M., De Voss, James J., McCarthy, James, Walter, Gimme H., Burne, Thomas H. J., Smith, Maree T., Tie, Jian-Ke and Williams, Craig M. (2019). Cyclooctatetraene: a bioactive cubane paradigm complement. Chemistry: A European Journal, 25 (11), 2729-2734. doi: 10.1002/chem.201806277
2018
Journal Article
Comparative analgesic efficacy of pregabalin administered according to either a prevention protocol or an intervention protocol in rats with cisplatin-induced peripheral neuropathy
Han, Felicity Y., Kuo, Andy, Nicholson, Janet R., Corradinni, Laura and Smith, Maree T. (2018). Comparative analgesic efficacy of pregabalin administered according to either a prevention protocol or an intervention protocol in rats with cisplatin-induced peripheral neuropathy. Clinical and Experimental Pharmacology and Physiology, 45 (10), 1067-1075. doi: 10.1111/1440-1681.12971
2018
Journal Article
In vivo profiling of four centrally administered opioids for antinociception, constipation and respiratory depression: between colony differences in Sprague Dawley rats
Kuo, Andy and Smith, Maree T. (2018). In vivo profiling of four centrally administered opioids for antinociception, constipation and respiratory depression: between colony differences in Sprague Dawley rats. Clinical and Experimental Pharmacology & Physiology, 45 (10), 1056-1066. doi: 10.1111/1440-1681.12972
2018
Journal Article
Corrigendum to: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere (Angewandte Chemie International Edition, (2016), 55, 11, (3580-3585), 10.1002/anie.201510675)
Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2018). Corrigendum to: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere (Angewandte Chemie International Edition, (2016), 55, 11, (3580-3585), 10.1002/anie.201510675). Angewandte Chemie - International Edition, 57 (28), 8359-8359. doi: 10.1002/anie.201711161
2018
Journal Article
Chronic low back pain: a mini-review on pharmacological management and pathophysiological insights from clinical and pre-clinical data
Park, Thomas S. W., Kuo, Andy and Smith, Maree T. (2018). Chronic low back pain: a mini-review on pharmacological management and pathophysiological insights from clinical and pre-clinical data. Inflammopharmacology, 26 (4), 1-18. doi: 10.1007/s10787-018-0493-x
2018
Journal Article
The somatostatin receptor-4 agonist J-2156 alleviates mechanical hypersensitivity in a rat model of breast cancer induced bone pain
Shenoy, Priyank A., Kuo, Andy, Khan, Nemat, Gorham, Louise, Nicholson, Janet, Corradini, Laura, Vetter, Irina and Smith, Maree T. (2018). The somatostatin receptor-4 agonist J-2156 alleviates mechanical hypersensitivity in a rat model of breast cancer induced bone pain. Frontiers in Pharmacology, 9 (MAY) 495, 495. doi: 10.3389/fphar.2018.00495
2018
Journal Article
Synthesis and Biological Evaluation of Fentanyl Analogues Modified at Phenyl Groups with Alkyls
Qin, Yajuan, Ni, Luofan, Shi, Jiawei, Zhu, Zhiying, Shi, Saijian, Lam, Ai-Leen, Magiera, Julia, Sekar, Sunderajhan, Kuo, Andy, Smith, Maree T. and Li, Tingyou (2018). Synthesis and Biological Evaluation of Fentanyl Analogues Modified at Phenyl Groups with Alkyls. ACS Chemical Neuroscience, 10 (1) acschemneuro.8b00363, 201-208. doi: 10.1021/acschemneuro.8b00363
2017
Journal Article
Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depression
Imam, Mohammad Zafar, Kuo, Andy, Ghassabian, Sussan and Smith, Maree T. (2017). Progress in understanding mechanisms of opioid-induced gastrointestinal adverse effects and respiratory depression. Neuropharmacology, 131, 238-255. doi: 10.1016/j.neuropharm.2017.12.032
2017
Journal Article
Pharmacological inhibition of the NLRP3 inflammasome as a potential target for multiple sclerosis induced central neuropathic pain
Khan, Nemat, Kuo, Andy, Brockman, David A, Cooper, Matthew A and Smith, Maree T (2017). Pharmacological inhibition of the NLRP3 inflammasome as a potential target for multiple sclerosis induced central neuropathic pain. Inflammopharmacology, 26 (1), 77-86. doi: 10.1007/s10787-017-0401-9
2017
Journal Article
Establishment and characterization of a novel rat model of mechanical low back pain using behavioral, pharmacologic and histologic methods
Muralidharan, Arjun, Park, Thomas S. W., Mackie, John T., Gimenez, Luiz G. S., Kuo, Andy, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2017). Establishment and characterization of a novel rat model of mechanical low back pain using behavioral, pharmacologic and histologic methods. Frontiers in Pharmacology, 8 493, 493.1-493.12. doi: 10.3389/fphar.2017.00493
2017
Journal Article
Optimization and in vivo profiling of a refined rat model of Walker 256 breast cancer cell-induced bone pain using behavioral, radiological, histological, immunohistochemical and pharmacological methods
Shenoy, Priyank, Kuo, Andy, Vetter, Irina and Smith, Maree T. (2017). Optimization and in vivo profiling of a refined rat model of Walker 256 breast cancer cell-induced bone pain using behavioral, radiological, histological, immunohistochemical and pharmacological methods. Frontiers in Pharmacology, 8 (JUL) 442, 442. doi: 10.3389/fphar.2017.00442
2016
Journal Article
The Walker 256 breast cancer cell-induced bone pain model in rats
Shenoy, Priyank A., Kuo, Andy, Vetter, Irina and Smith, Maree T. (2016). The Walker 256 breast cancer cell-induced bone pain model in rats. Frontiers in Pharmacology, 7 (AUG) 286, 286. doi: 10.3389/fphar.2016.00286
2016
Journal Article
Comparison of burrowing and stimuli-evoked pain behaviors as end-points in rat models of inflammatory pain and peripheral neuropathic pain
Muralidharan, Arjun, Kuo, Andy, Jacob, Meera, Lourdesamy, Jacintha S., Melo Sores Pinho De Carvalho, Lara, Nicholson, Janet R., Corradini, Laura and Smith, Maree T. (2016). Comparison of burrowing and stimuli-evoked pain behaviors as end-points in rat models of inflammatory pain and peripheral neuropathic pain. Frontiers in Behavioral Neuroscience, 10 (88) 88, 88. doi: 10.3389/fnbeh.2016.00088
2016
Journal Article
Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere
Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2016). Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere. Angewandte Chemie International Edition, 55 (11), 8359-8359. doi: 10.1002/anie.201681161
2016
Journal Article
Validating Eaton's hypothesis: cubane as a benzene bioisostere
Chalmers, Benjamin A., Xing, Hui, Houston, Sevan, Clark, Charlotte, Ghassabian, Sussan, Kuo, Andy, Cao, Benjamin, Reitsma, Andrea, Murray, Cody-Ellen P., Stok, Jeanette E., Boyle, Glen M., Pierce, Carly J., Littler, Stuart W., Winkler, David A., Bernhardt, Paul V., Pasay, Cielo, De Voss, James J., McCarthy, James, Parsons, Peter G., Walter, Gimme H., Smith, Maree T., Cooper, Helen M., Nilsson, Susan K., Tsanaktsidis, John, Savage, G. Paul and Williams, Craig M. (2016). Validating Eaton's hypothesis: cubane as a benzene bioisostere. Angewandte Chemie (International Edition), 55 (11), 3580-3585. doi: 10.1002/anie.201510675
2014
Journal Article
Theoretical and practical applications of the intracerebroventricular route for CSF sampling and drug administration in CNS drug discovery research: a mini review
Kuo, Andy and Smith, Maree T. (2014). Theoretical and practical applications of the intracerebroventricular route for CSF sampling and drug administration in CNS drug discovery research: a mini review. Journal of Neuroscience Methods, 233, 166-171. doi: 10.1016/j.jneumeth.2014.06.006
Funding
Past funding
Supervision
Availability
- Dr Andy Kuo is:
- Available for supervision
Looking for a supervisor? Read our advice on how to choose a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Discovery and Pharmacological Evaluation of Novel Analgesics for the Relief of Ross River Virus Induced Chronic Pain
Associate Advisor
Other advisors: Professor Kate Schroder, Dr Mohammad Zafar Imam, Emeritus Professor Maree Smith
-
Doctor Philosophy
The therapeutic potential of targeting the C5a-C5aR1 axis in neuropathic pain: linking neuroinflammation and sensitisation
Associate Advisor
Other advisors: Emeritus Professor Maree Smith, Professor Trent Woodruff, Dr Amanda Kijas, Dr Felicity Han
-
Doctor Philosophy
Discovery and development of an Antibiotic Modulator to Break Antibiotic Resistance in a Mouse Infection Model
Associate Advisor
Other advisors: Professor Mark Walker, Emeritus Professor Maree Smith
-
Doctor Philosophy
Novel long-acting and orally delivered conotoxin-based peptides with both analgesic efficacy and disease modifying potential
Associate Advisor
Other advisors: Associate Professor Richard Clark, Emeritus Professor Maree Smith
Completed supervision
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2019
Doctor Philosophy
Chronic low back pain: pathobiological investigations towards improved treatments
Associate Advisor
Other advisors: Emeritus Professor Maree Smith
-
2019
Doctor Philosophy
Analgesic efficacy of novel opioid compounds relative to adverse effects in rats
Associate Advisor
Other advisors: Emeritus Professor Maree Smith
-
2018
Doctor Philosophy
Establishment, optimization and characterization of a rat model of breast cancer induced bone pain
Associate Advisor
Other advisors: Emeritus Professor Maree Smith, Professor Irina Vetter
Media
Enquiries
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