Overview
Background
Dr Li Li is a Honorary Associate Professor at Australian Institute for Bioengineering and Nanotechnology. She received her PhD in Chemical Engineering from China University of Petroleum.
In 2007, she joined the University of Queensland (UQ) as a postdoctoral research fellow in the ARC Centre of Excellence for Functional Nanomaterials, working on nanoparticles and nanomaterials for renewable energy production and storage, environment technology and catalysis including hydrogen production and storage, environmental protection, and gas adsorption. In 2011, she was awarded UQ Postdoctoral Fellowship under the supervision of Prof. Zhi Ping (Gordon) Xu, working on engineered nanomaterials in healthcare and environment control. After Postdoctoral Fellowship, she was awarded Advance Queensland Research Fellow in 2016. Her research focuses on design and engineering functional nanomaterials for drug/gene delivery, sustainable release and oral vaccine delivery for human health and animal health management. Since 2011, she has attracted 22+ research funding including Advance Queensland Fellowship (Mid), Queensland smart future fund, UQ Postdoctoral Research Fellowship, 3 UQ grants and 2 international collaboration projects. Moreover, she has a strong linkage with industry partners on the development of functional targeted nano-delivery systems to enhance the health of farm animals.
Availability
- Dr Li Li is:
- Not available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy of Chemical Engineering and Technology, China University of Petroleum
Research interests
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Design and development of functional nanoparticles for targeted drug delivery and vaccine delivery
Functional nanoparticles including bio-clay materials and nanoemulsion are employed to efficiently deliver drug or vaccine for effective therapeutic treatment
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Engineering novel nanoplatform for oral vaccine delivery
Development of cost-effective nanoplatforms such as solid lipid nanoparticles and hierarchical nanoparticles to efficiently deliver antigens to enhance immune response.
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Development of nano-formulations in feed for disease control in poultry
Develop a cost-effective oral delivery platform for anti-bacterial plant extracts and antigens combined with animal feeds to control the bacterial infections in poultry.
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Porous materials such as ordered mesoporous silicas and carbon materials for energy production and storage.
Works
Search Professor Li Li’s works on UQ eSpace
2022
Journal Article
Nanoclay-based sensor composites for the facile detection of molecular antioxidants
Szerlauth, Adél, Szalma, Lilla, Muráth, Szabolcs, Sáringer, Szilárd, Varga, Gábor, Li, Li and Szilágyi, István (2022). Nanoclay-based sensor composites for the facile detection of molecular antioxidants. The Analyst, 147 (7), 1367-1374. doi: 10.1039/d1an02352g
2022
Journal Article
Dynamic nano-assemblies based on two-dimensional inorganic nanoparticles: construction and preclinical demonstration
Sun, Luyao, Wang, Jingjing, Li, Li and Xu, Zhi Ping (2022). Dynamic nano-assemblies based on two-dimensional inorganic nanoparticles: construction and preclinical demonstration. Advanced Drug Delivery Reviews, 180 114031, 1-20. doi: 10.1016/j.addr.2021.114031
2021
Journal Article
Biomimetic 2D layered double hydroxide nanocomposites for hyperthermia-facilitated homologous targeting cancer photo-chemotherapy
Wang, Jingjing, Sun, Luyao, Liu, Jie, Sun, Bing, Li, Li and Xu, Zhi Ping (2021). Biomimetic 2D layered double hydroxide nanocomposites for hyperthermia-facilitated homologous targeting cancer photo-chemotherapy. Journal of Nanobiotechnology, 19 (1) 351, 351. doi: 10.1186/s12951-021-01096-9
2021
Book Chapter
Recent advances in cell‐mediated drug delivery systems for nanomedicine and imaging
Li, Li and Qi, Zhi (2021). Recent advances in cell‐mediated drug delivery systems for nanomedicine and imaging. Fundamentals of drug delivery. (pp. 263-284) Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/9781119769644.ch10
2021
Journal Article
Enhanced Mucosal Transport of Polysaccharide–Calcium Phosphate Nanocomposites for Oral Vaccination
Cao, Pei, Wang, Jingjing, Sun, Bing, Rewatkar, Prarthana, Popat, Amirali, Fu, Changkui, Peng, Hui, Xu, Zhi Ping and Li, Li (2021). Enhanced Mucosal Transport of Polysaccharide–Calcium Phosphate Nanocomposites for Oral Vaccination. ACS Applied Bio Materials, 4 (11) acsabm.1c00798, 7865-7878. doi: 10.1021/acsabm.1c00798
2021
Journal Article
Immunostimulatory photochemotherapeutic nanocapsule for enhanced colon cancer treatment
Liu, Jie, Movahedi, Fatemeh, Sun, Bing, Sun, Luyao, Zhang, Bing, Wang, Jingjing, Li, Li and Xu, Zhi Ping (2021). Immunostimulatory photochemotherapeutic nanocapsule for enhanced colon cancer treatment. Nanophotonics, 10 (12), 1-17. doi: 10.1515/nanoph-2021-0202
2021
Journal Article
Albumin-stabilized layered double hydroxide nanoparticles synergized combination chemotherapy for colorectal cancer treatment
Li, Li, Qian, Yujin, Sun, Luyao, Han, Felicity Y., Zhang, Run, Wang, Peng-Yuan and Xu, Zhi Ping (2021). Albumin-stabilized layered double hydroxide nanoparticles synergized combination chemotherapy for colorectal cancer treatment. Nanomedicine: Nanotechnology, Biology, and Medicine, 34 102369, 102369. doi: 10.1016/j.nano.2021.102369
2021
Journal Article
Chitosan nanomedicine in cancer therapy: targeted delivery and cellular uptake
Mushtaq, Asim, Li, Li, A., Anitha and Grøndahl, Lisbeth (2021). Chitosan nanomedicine in cancer therapy: targeted delivery and cellular uptake. Macromolecular Bioscience, 21 (5) 2100005, e2100005. doi: 10.1002/mabi.202100005
2021
Journal Article
Calcium-bisphosphonate nanoparticle platform as a prolonged nanodrug and bone-targeted delivery system for bone diseases and cancers
Lin, Yanling, Villacanas, Maria G., Zou, Hong, Liu, Hangrui, Carcedo, Ines G., Wu, Yilun, Sun, Bing, Wu, Xiaoxin, Prasadam, Indira, Monteiro, Michael J., Li, Li, Xu, Zhi Ping and Gu, Wenyi (2021). Calcium-bisphosphonate nanoparticle platform as a prolonged nanodrug and bone-targeted delivery system for bone diseases and cancers. ACS Applied Bio Materials, 4 (3) acsabm.0c01455, 2490-2501. doi: 10.1021/acsabm.0c01455
2021
Journal Article
Development of CaP nanocomposites as photothermal actuators for doxorubicin delivery to enhance breast cancer treatment
Liu, Jie, Li, Li, Zhang, Run and Xu, Zhi Ping (2021). Development of CaP nanocomposites as photothermal actuators for doxorubicin delivery to enhance breast cancer treatment. Journal of Materials Science and Technology, 63, 73-80. doi: 10.1016/j.jmst.2020.02.029
2021
Journal Article
Synergistic cancer photochemotherapy via layered double hydroxide-based trimodal nanomedicine at very low therapeutic doses
Liu, Jianping, Sun, Luyao, Li, Li, Zhang, Run and Xu, Zhi Ping (2021). Synergistic cancer photochemotherapy via layered double hydroxide-based trimodal nanomedicine at very low therapeutic doses. ACS Applied Materials and Interfaces, 13 (6) acsami.0c23143, 7115-7126. doi: 10.1021/acsami.0c23143
2021
Journal Article
Creating structural defects of drug‐free copper‐containing layered double hydroxide nanoparticles to synergize photothermal/photodynamic/chemodynamic cancer therapy
Sun, Luyao, Wang, Jingjing, Liu, Jianping, Li, Li and Xu, Zhi Ping (2021). Creating structural defects of drug‐free copper‐containing layered double hydroxide nanoparticles to synergize photothermal/photodynamic/chemodynamic cancer therapy. Small Structures, 2 (2) 2000112, 2000112. doi: 10.1002/sstr.202000112
2021
Journal Article
Synergistic inhibition of drug-resistant colon cancer growth with PI3K/mTOR dual inhibitor BEZ235 and nano-emulsioned paclitaxel via reducing multidrug resistance and promoting apoptosis
Hu, Yali, Zhang, Kunpeng, Zhu, Xingyao, Zheng, Xiuyan, Wang, Chao, Niu, Xiao, Jiang, Teng, Ji, Xinhua, Zhao, Weilin, Pang, Lijuan, Qi, Yan, Li, Feng, Li, Li, Xu, Zhiping, Gu, Wenyi and Zou, Hong (2021). Synergistic inhibition of drug-resistant colon cancer growth with PI3K/mTOR dual inhibitor BEZ235 and nano-emulsioned paclitaxel via reducing multidrug resistance and promoting apoptosis. International Journal of Nanomedicine, 16, 2173-2186. doi: 10.2147/IJN.S290731
2020
Journal Article
Enhanced oral vaccine efficacy of polysaccharide-coated calcium phosphate nanoparticles
Cao, Pei, Han, Felicity Y., Grøndahl, Lisbeth, Xu, Zhi Ping and Li, Li (2020). Enhanced oral vaccine efficacy of polysaccharide-coated calcium phosphate nanoparticles. ACS Omega, 5 (29), 18185-18197. doi: 10.1021/acsomega.0c01792
2020
Journal Article
Charge reversion simultaneously enhances tumor accumulation and cell uptake of layered double hydroxide nanohybrids for effective imaging and therapy
Liu, Jianping, Wu, Yilun, Fu, Changkui, Li, Bei, Li, Li, Zhang, Run, Xu, Tiefeng and Xu, Zhi Ping (2020). Charge reversion simultaneously enhances tumor accumulation and cell uptake of layered double hydroxide nanohybrids for effective imaging and therapy. Small, 16 (31) 2002115, e2002115. doi: 10.1002/smll.202002115
2020
Journal Article
Human platelet lysate supports mouse skeletal myoblast growth but suppresses cell fusion on nanogrooves
Tao, Xuelian, Tao, Xuelian, Du, Ping, Du, Ping, Li, Li, Lin, Jiao, Lin, Jiao, Shi, Yue, Shi, Yue, Wang, Peng-Yuan, Wang, Peng-Yuan and Wang, Peng-Yuan (2020). Human platelet lysate supports mouse skeletal myoblast growth but suppresses cell fusion on nanogrooves. ACS Applied Bio Materials, 3 (6), 3594-3604. doi: 10.1021/acsabm.0c00230
2020
Journal Article
TAT-based therapies as an adjuvant for an HIV-1 functional cure
Jin, Hongping, Li, Dongsheng, Lin, Min-Hsuan, Li, Li and Harrich, David (2020). TAT-based therapies as an adjuvant for an HIV-1 functional cure. Viruses, 12 (4) 415, 415. doi: 10.3390/v12040415
2020
Journal Article
Nanoclay-induced bacterial flocculation for infection confinement
Malekkhaiat Häffner, Sara, Nyström, Lina, Strömstedt, Adam A., Li, Li, van der Plas, Mariena J.A. and Malmsten, Martin (2020). Nanoclay-induced bacterial flocculation for infection confinement. Journal of Colloid and Interface Science, 562, 71-80. doi: 10.1016/j.jcis.2019.11.110
2020
Journal Article
Recent advances in heparinization of polymeric membranes for enhanced continuous blood purification
Shan, Liang, Sun, Yunbo, Shan, Feng, Li, Li and Xu, Zhi Ping (2020). Recent advances in heparinization of polymeric membranes for enhanced continuous blood purification. Journal of Materials Chemistry B, 8 (5), 878-894. doi: 10.1039/c9tb02515d
2020
Journal Article
2D layered double hydroxide nanoparticles: recent progress toward preclinical/clinical nanomedicine
Cao, Zhenbang, Li, Bei, Sun, Luyao, Li, Li, Xu, Zhi Ping and Gu, Zi (2020). 2D layered double hydroxide nanoparticles: recent progress toward preclinical/clinical nanomedicine. Small Methods, 4 (2) 1900343, 1900343. doi: 10.1002/smtd.201900343
Funding
Current funding
Supervision
Availability
- Dr Li Li is:
- Not available for supervision
Supervision history
Current supervision
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Doctor Philosophy
New Strategies in Targeted Proteolysis with Nanoparticle-Mediated mRNA Delivery
Associate Advisor
Other advisors: Dr Run Zhang
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Doctor Philosophy
Functional piezoelectric scaffolds for bone tissue regeneration
Associate Advisor
Other advisors: Dr Run Zhang
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Doctor Philosophy
Development of Layered Double Hydroxide Nanoparticles Based Platform for Delivery
Associate Advisor
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Doctor Philosophy
The impact of nanoplastics and microplastics on health and the environment
Associate Advisor
Other advisors: Dr Nick Fletcher, Dr Muxina Konarova
Completed supervision
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2023
Doctor Philosophy
Advancements in Cancer Chemo-Immunotherapy: Pioneering Strategies for Combating Immunosuppressive Barriers
Principal Advisor
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2025
Doctor Philosophy
Understanding Interactions of Nano-cellulose Suspensions with Plant Leaves for Enhancing Topical Delivery of Soluble Bioactive and Particulates
Associate Advisor
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2022
Doctor Philosophy
Development and in vitro evaluation of a targeted nanotherapeutic system for bone metastasised breast cancer
Associate Advisor
Other advisors: Professor Lisbeth Grondahl
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2022
Doctor Philosophy
Layered double hydroxide nanoparticles tailored to target tumor microenvironment as multifunctional nanoplatforms for synergistic cancer therapy
Associate Advisor
Other advisors: Dr Run Zhang
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2022
Doctor Philosophy
Nanomaterial-enhanced cancer combination therapy by co-delivering chemo-immunotherapeutic agents
Associate Advisor
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2021
Doctor Philosophy
Novel Cu-LDH-based nanomedicine for combination cancer therapy
Associate Advisor
Other advisors: Dr Run Zhang
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2021
Master Philosophy
Controlled synthesis of defect-rich transition metal containing layered double hydroxide nanosheets for applications in biomedicine and electrochemical catalysis
Associate Advisor
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2017
Doctor Philosophy
Photocatalysts with adsorption property for dye-contaminated water purification
Associate Advisor
Media
Enquiries
Contact Dr Li Li directly for media enquiries about:
- Cancer immuontherapy
- functional nanomateirals in biomedical application
- gene delivery
- mRNA targeted delivery
- Nanomedicine
- oral vaccine
- sustainable release
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