
Overview
Background
Dr Li Li is a Senior Research Fellow at Australian Institute for Bioengineering and Nanotechnology. She received her PhD in Chemical Engineering from China University of Petroleum.
In 2007, she joined the University of Queensland (UQ) as a postdoctoral research fellow in the ARC Centre of Excellence for Functional Nanomaterials, working on nanoparticles and nanomaterials for renewable energy production and storage, environment technology and catalysis including hydrogen production and storage, environmental protection, and gas adsorption. In 2011, she was awarded UQ Postdoctoral Fellowship under the supervision of Prof. Zhi Ping (Gordon) Xu, working on engineered nanomaterials in healthcare and environment control. After Postdoctoral Fellowship, she was awarded Advance Queensland Research Fellow in 2016. Her research focuses on design and engineering functional nanomaterials for drug/gene delivery, sustainable release and oral vaccine delivery for human health and animal health management. Since 2011, she has attracted 22+ research funding including Advance Queensland Fellowship (Mid), Queensland smart future fund, UQ Postdoctoral Research Fellowship, 3 UQ grants and 2 international collaboration projects. Moreover, she has a strong linkage with industry partners on the development of functional targeted nano-delivery systems to enhance the health of farm animals.
Availability
- Dr Li Li is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy of Chemical Engineering and Technology, China University of Petroleum
Research interests
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Design and development of functional nanoparticles for targeted drug delivery and vaccine delivery
Functional nanoparticles including bio-clay materials and nanoemulsion are employed to efficiently deliver drug or vaccine for effective therapeutic treatment
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Engineering novel nanoplatform for oral vaccine delivery
Development of cost-effective nanoplatforms such as solid lipid nanoparticles and hierarchical nanoparticles to efficiently deliver antigens to enhance immune response.
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Development of nano-formulations in feed for disease control in poultry
Develop a cost-effective oral delivery platform for anti-bacterial plant extracts and antigens combined with animal feeds to control the bacterial infections in poultry.
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Porous materials such as ordered mesoporous silicas and carbon materials for energy production and storage.
Works
Search Professor Li Li’s works on UQ eSpace
2016
Journal Article
Efficient drug delivery using SiO2-layered double hydroxide nanocomposites
Li, Li, Gu, Zi, Gu, Wenyi, Liu, Jian and Xu, Zhi Ping (2016). Efficient drug delivery using SiO2-layered double hydroxide nanocomposites. Journal of Colloid and Interface Science, 470, 47-55. doi: 10.1016/j.jcis.2016.02.042
2016
Journal Article
Synergistic inhibition of colon cancer cell growth with nanoemulsion-loaded paclitaxel and PI3K/ mTOR dual inhibitor BEZ235 through apoptosis
Zou, Hong, Li, Li, Garcia Carcedo, Ines, Xu, Zhi Ping, Monteiro, Michael and Gu, Wenyi (2016). Synergistic inhibition of colon cancer cell growth with nanoemulsion-loaded paclitaxel and PI3K/ mTOR dual inhibitor BEZ235 through apoptosis. International Journal of Nanomedicine, 11, 1947-1958. doi: 10.2147/IJN.S100744
2016
Journal Article
Uptake and degradation of Orange II by zinc aluminum layered double oxides
Zhang, Luhong, Xiong, Zhigang, Li, Li, Burt, Ryan and Zhao, X. S. (2016). Uptake and degradation of Orange II by zinc aluminum layered double oxides. Journal of Colloid and Interface Science, 469, 224-230. doi: 10.1016/j.jcis.2016.02.005
2016
Journal Article
Physiologically based pharmacokinetic model for long-circulating inorganic nanoparticles
Liang, Xiaowen, Wang, Haolu, Grice, Jeffrey E., Li, Li, Liu, Xin, Xu, Zhi Ping and Roberts, Michael S. (2016). Physiologically based pharmacokinetic model for long-circulating inorganic nanoparticles. Nano Letters, 16 (2), 939-945. doi: 10.1021/acs.nanolett.5b03854
2016
Journal Article
Direct synthesis of layered double hydroxide nanosheets for efficient siRNA delivery
Li, L., Gu, Z., Gu, W. Y. and Xu, Z. P. (2016). Direct synthesis of layered double hydroxide nanosheets for efficient siRNA delivery. RSC Advances, 6 (98), 95518-95526. doi: 10.1039/c6ra19225d
2016
Journal Article
Aggregation of layered double hydroxide nanoparticles in the presence of heparin: towards highly stable delivery systems
Pavlovic, Marko, Li, Li, Dits, Francois, Gu, Zi, Adok-Sipiczki, Monkia and Szilagyi, Istvan (2016). Aggregation of layered double hydroxide nanoparticles in the presence of heparin: towards highly stable delivery systems. RSC Advances, 6 (20), 16159-16167. doi: 10.1039/c5ra26072h
2015
Journal Article
Preparation of optimized lipid-coated calcium phosphate nanoparticles for enhanced in vitro gene delivery to breast cancer cells
Tang, Jie, Li, Li, Howard, Christopher B., Mahler, Stephen M., Huang, Leaf and Xu, Zhi Ping (2015). Preparation of optimized lipid-coated calcium phosphate nanoparticles for enhanced in vitro gene delivery to breast cancer cells. Journal of Materials Chemistry B, 3 (33), 6805-6812. doi: 10.1039/c5tb00912j
2015
Journal Article
Pre-coating layered double hydroxide nanoparticles with albumin to improve colloidal stability and cellular uptake
Gu, Zi, Zuo, Hualia, Li, Li, Wu, Aihua and Xu, Zhi Ping (2015). Pre-coating layered double hydroxide nanoparticles with albumin to improve colloidal stability and cellular uptake. Journal of Materials Chemistry B, 3 (16), 3331-3339. doi: 10.1039/c5tb00248f
2015
Journal Article
Amine-functionalized SiO2 nanodot-coated layered double hydroxide nanocomposites for enhanced gene delivery
Li, Li, Gu, Wenyi, Liu, Jian, Yan, Shiyu and Xu, Zhi Ping (2015). Amine-functionalized SiO2 nanodot-coated layered double hydroxide nanocomposites for enhanced gene delivery. Nano Research, 8 (2), 682-694. doi: 10.1007/s12274-014-0552-6
2015
Conference Publication
Efficient drug delivery for cancer treatment using Si02-LDH nanocomposites
Li, L., Gu, Z., Gu, W. Y., Liu, J. and Xu, Z. P. (2015). Efficient drug delivery for cancer treatment using Si02-LDH nanocomposites. 10th Annual TechConnect World Innovation Conference and Expo, Held Jointly with the 18th Annual Nanotech Conference and Expo, and the 2015 National SBIR/STTR Conference, Washington, DC, United States, 14-17 June 2015. Taylor and Francis.
2014
Journal Article
Potential foliar fertilizers with copper and zinc dual micronutrients in nanocrystal suspension
Li, Peng, Li, Li, Du, Yumei, Hampton, Marc A., Nguyen, Anh V., Huang, Longbin, Rudolph, Victor and Xu, Zhi Ping (2014). Potential foliar fertilizers with copper and zinc dual micronutrients in nanocrystal suspension. Journal of Nanoparticle Research, 16 (11) 2669. doi: 10.1007/s11051-014-2669-7
2014
Journal Article
Efficient selective catalytic reduction of NO by novel carbon-doped metal catalysts made from electroplating sludge
Zhang, Jia, Zhang, Jingyi, Xu, Yunfeng, Su, Huimin, Li, Xiaoman, Zhou, Ji Zhi, Qian, Guangren, Li, Li and Xu, Zhi Ping (2014). Efficient selective catalytic reduction of NO by novel carbon-doped metal catalysts made from electroplating sludge. Environmental Science and Technology, 48 (19), 11497-11503. doi: 10.1021/es502391y
2014
Journal Article
Quick and efficient co-treatment of Zn2+/Ni2+ and CN- via the formation of Ni(CN)4 2- intercalated larger ZnAl-LDH crystals
Zhou, Ji Zhi, Liang, Ying, Zhang, Jia, Li, Li, Xu, Yunfeng, Ruan, Xiuxiu, Qian, Guangren and Xu, Zhi Ping (2014). Quick and efficient co-treatment of Zn2+/Ni2+ and CN- via the formation of Ni(CN)4 2- intercalated larger ZnAl-LDH crystals. Journal of Hazardous Materials, 279, 141-147. doi: 10.1016/j.jhazmat.2014.07.001
2014
Journal Article
Effective inhibition of colon cancer cell growth with MgAl-layered double hydroxide (LDH) loaded 5-FU and PI3K/mTOR dual inhibitor BEZ-235 through apoptotic pathways
Chen, Jiezhong, Shao, Renfu, Li, Li, Xu, Zhi Ping and Gu, Wenyi (2014). Effective inhibition of colon cancer cell growth with MgAl-layered double hydroxide (LDH) loaded 5-FU and PI3K/mTOR dual inhibitor BEZ-235 through apoptotic pathways. International Journal of Nanomedicine, 9 (1), 3403-3411. doi: 10.2147/IJN.S61633
2014
Journal Article
Preparation and characterisation of manganese and iron compounds as potential control-release foliar fertilisers
Li, Peng, Du, Yumei, Li, Li, Huang, Longbin, Rudolph, Victor, Nguyen, Anh V. and Xu, Zhi Ping (2014). Preparation and characterisation of manganese and iron compounds as potential control-release foliar fertilisers. Biointerface Research in Applied Chemistry, 4 (3), 746-753.
2014
Journal Article
Influence of hydrothermal treatment on physicochemical properties and drug release of anti-inflammatory drugs of intercalated layered double hydroxide nanoparticles
Gu, Zi, Wu, Aihua, Li, Li and Xu, Zhi Ping (2014). Influence of hydrothermal treatment on physicochemical properties and drug release of anti-inflammatory drugs of intercalated layered double hydroxide nanoparticles. Pharmaceutics, 6 (2), 235-248. doi: 10.3390/pharmaceutics6020235
2014
Journal Article
Co-delivery of siRNAs and anti-cancer drugs using layered double hydroxide nanoparticles
Li, Li, Gu, Wenyi, Chen, Jiezhong, Chen, Weiyu and Xu, Zhi P. (2014). Co-delivery of siRNAs and anti-cancer drugs using layered double hydroxide nanoparticles. Biomaterials, 35 (10), 3331-3339. doi: 10.1016/j.biomaterials.2013.12.095
2013
Journal Article
Catalytic ammonia decomposition for CO-free hydrogen generation over Ru/Cr2O3 catalysts
Li, Li, Wang, Yinghua, Xu, Zhi Ping and Zhu, Zhonghua (2013). Catalytic ammonia decomposition for CO-free hydrogen generation over Ru/Cr2O3 catalysts. Applied Catalysis A: General, 467, 246-252. doi: 10.1016/j.apcata.2013.07.003
2013
Journal Article
Selective catalytic oxidation of H2S over iron oxide supported on alumina-intercalated Laponite clay catalysts
Zhang, Xin, Dou, Guangyu, Wang, Zhuo, Li, Li, Wang, Yufei, Wang, Hailin and Hao, Zhengping (2013). Selective catalytic oxidation of H2S over iron oxide supported on alumina-intercalated Laponite clay catalysts. Journal of Hazardous Materials, 260, 104-111. doi: 10.1016/j.jhazmat.2013.05.008
2013
Journal Article
High capacitance electrode materials based on layered double hydroxides prepared by non-aqueous precipitation
Xu, Zhi Ping, Li, Li, Cheng, Ching-Yuan, Ding, Ronggang and Zhou, Chunhui (2013). High capacitance electrode materials based on layered double hydroxides prepared by non-aqueous precipitation. Applied Clay Science, 74, 102-108. doi: 10.1016/j.clay.2012.06.015
Funding
Current funding
Supervision
Availability
- Dr Li Li is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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Development of nano-formulations in feed for disease control in poultry
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Engineering novel nanoplatform for oral vaccine delivery
Supervision history
Current supervision
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Doctor Philosophy
Development of Layered Double Hydroxide Nanoparticles Based Platform for Delivery
Associate Advisor
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Doctor Philosophy
New Strategies in Targeted Proteolysis with Nanoparticle-Mediated mRNA Delivery
Associate Advisor
Other advisors: Dr Run Zhang
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Doctor Philosophy
Understanding Interactions of Nano-cellulose Suspensions with Plant Leaves for Enhancing Topical Delivery of Soluble Bioactive and Particulates
Associate Advisor
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Doctor Philosophy
Functional piezoelectric scaffolds for bone tissue regeneration
Associate Advisor
Other advisors: Dr Run Zhang
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Doctor Philosophy
The impact of nanoplastics and microplastics on health and the environment
Associate Advisor
Other advisors: Dr Nick Fletcher, Dr Muxina Konarova
Completed supervision
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2023
Doctor Philosophy
Advancements in Cancer Chemo-Immunotherapy: Pioneering Strategies for Combating Immunosuppressive Barriers
Principal Advisor
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2022
Doctor Philosophy
Layered double hydroxide nanoparticles tailored to target tumor microenvironment as multifunctional nanoplatforms for synergistic cancer therapy
Associate Advisor
Other advisors: Dr Run Zhang
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2022
Doctor Philosophy
Nanomaterial-enhanced cancer combination therapy by co-delivering chemo-immunotherapeutic agents
Associate Advisor
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2022
Doctor Philosophy
Development and in vitro evaluation of a targeted nanotherapeutic system for bone metastasised breast cancer
Associate Advisor
Other advisors: Professor Lisbeth Grondahl
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2021
Doctor Philosophy
Novel Cu-LDH-based nanomedicine for combination cancer therapy
Associate Advisor
Other advisors: Dr Run Zhang
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2021
Master Philosophy
Controlled synthesis of defect-rich transition metal containing layered double hydroxide nanosheets for applications in biomedicine and electrochemical catalysis
Associate Advisor
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2017
Doctor Philosophy
Photocatalysts with adsorption property for dye-contaminated water purification
Associate Advisor
Media
Enquiries
Contact Dr Li Li directly for media enquiries about:
- Cancer immuontherapy
- functional nanomateirals in biomedical application
- gene delivery
- mRNA targeted delivery
- Nanomedicine
- oral vaccine
- sustainable release
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