Overview
Background
Dr Caroline Cooper, BMedSci, MB,BS (Hons), FRCPA, GCertHE, MPhil, graduated with a Bachelor of Medicine and Surgery from the University of Tasmania and was awarded Fellowship of the Royal Australasian College of Pathologists in Anatomical Pathology in 2007. She completed a Masters of Philosophy in Biomarkers in Breast Cancer, Adenoid Cystic Carcinoma and Perineural spread of squamous cell carcinoma in 2024 at the Simpson Lab at the Frazer Institute. Her areas of research include translational pathology, biomarker implementation and diagnostic precision in cancer. Caroline is a Senior Anatomical Pathologist and co-director of Anatomical Pathology, Pathology Queensland at the Princess Alexandra Hospital, Brisbane.
Availability
- Dr Caroline Cooper is:
- Available for supervision
Research impacts
Morphological, spatial and biomarker profiling in gastrointestinal, lung and cutaneous cancers to eludidate improved approaches to diagnosis and patient care.
Works
Search Professor Caroline Cooper’s works on UQ eSpace
2024
Conference Publication
Spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma revealed immune cell type infiltration into the TME as a predictor of immunotherapy response
Sadeghirad, Habib, Tan, Chin Wee, Liu, Ning, Monkman, James, Cooper, Caroline, O’Byrne, Ken, Davis, Melissa, Hughes, Brett and Kulasinghe, Arutha (2024). Spatial profiling of the tumor microenvironment in head and neck squamous cell carcinoma revealed immune cell type infiltration into the TME as a predictor of immunotherapy response. American Association for Cancer Research Annual Meeting 2024, San Diego, CA United States, 5-10 April 2024. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2024-1154
2024
Journal Article
In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection
Tan, Chin Wee, Chen, Jinjin, Liu, Ning, Bhuva, Dharmesh D., Blick, Tony, Monkman, James, Cooper, Caroline, Kharbanda, Malvika, Feher, Kristen, Phipson, Belinda, Killingbeck, Emily E., Pan, Liuliu, Kim, Youngmi, Liang, Yan, Nam, Andy, Leon, Michael, Souza-Fonseca-Guimaraes, Paulo, Nagashima, Seigo, Camargo Martins, Ana Paula, Machado-Souza, Cleber, de Noronha, Lucia, Tang, Benjamin, Short, Kirsty, Fraser, John, Belz, Gabrielle T., Souza-Fonseca-Guimaraes, Fernando, Kulasinghe, Arutha and Davis, Melissa J. (2024). In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection. eBioMedicine, 101 105016, 1-4. doi: 10.1016/j.ebiom.2024.105016
2024
Journal Article
Disseminated thymoma in pleural fluid: an unusual case
Berry, Kate and Cooper, Caroline (2024). Disseminated thymoma in pleural fluid: an unusual case. Diagnostic Cytopathology, 52 (2), 131-135. doi: 10.1002/dc.25266
2024
Journal Article
Detailed DNA methylation characterisation of phyllodes tumours identifies a signature of malignancy and distinguishes phyllodes from metaplastic breast carcinoma
Meyer, Braydon, Stirzaker, Clare, Ramkomuth, Sonny, Harvey, Kate, Chan, Belinda, Lee, Cheok Soon, Karim, Rooshdiya, Deng, Niantao, Avery-Kiejda, Kelly A., Scott, Rodney J., Lakhani, Sunil, Fox, Stephen, Robbins, Elizabeth, Shin, Joo-Shik, Beith, Jane, Gill, Anthony, Sioson, Loretta, Chan, Charles, Krishnaswamy, Mrudula, Cooper, Caroline, Warrier, Sanjay, Mak, Cindy, Rasko, John E.J., Bailey, Charles G., Swarbrick, Alexander, Clark, Susan J., O'Toole, Sandra and Pidsley, Ruth (2024). Detailed DNA methylation characterisation of phyllodes tumours identifies a signature of malignancy and distinguishes phyllodes from metaplastic breast carcinoma. Journal of Pathology, 262 (4), 480-494. doi: 10.1002/path.6250
2023
Journal Article
Real-world prevalence of PD-L1 expression in non-small cell lung cancer: an Australia-wide multi-centre retrospective observational study
Russell, Prudence A., Farrall, Alexandra L., Prabhakaran, Sarita, Asadi, Khashayar, Barrett, Wade, Cooper, Caroline, Cooper, Wendy, Cotton, Samuel, Duhig, Edwina, Egan, Matthew, Fox, Stephen, Godbolt, David, Gupta, Shilpa, Hassan, Aniza, Leslie, Connull, Leong, Trishe, Moffat, David, Qiu, Min Ru, Sivasubramaniam, Vanathi, Skerman, Joanna, Snell, Cameron, Walsh, Michael, Whale, Karen and Klebe, Sonja (2023). Real-world prevalence of PD-L1 expression in non-small cell lung cancer: an Australia-wide multi-centre retrospective observational study. Pathology, 55 (7), 922-928. doi: 10.1016/j.pathol.2023.08.008
2023
Conference Publication
EP06.02-01 Prevalence of PD-L1 Expression in Non-Small Cell Lung Cancer: a Real-World Australian Perspective
Prabhakaran, S., Russell, P.A., Farrall, A.L., Asadi, K., Barrett, W., Cooper, C., Cooper, W., Duhig, E.E., Egan, M., Fox, S., Godbolt, D., Gupta, S., Cotton, S., Leslie, C., Leong, T., Moffat, D., Qiu, M., Sivasubramaniam, V., Snell, C., Skerman, J., Walsh, M., Whale, K. and Klebe, S. (2023). EP06.02-01 Prevalence of PD-L1 Expression in Non-Small Cell Lung Cancer: a Real-World Australian Perspective. 2023 World Conference on Lung Cancer, Singapore, 9-12 September 2023. New York, NY United States: Elsevier. doi: 10.1016/j.jtho.2023.09.886
2023
Journal Article
Pathological features associated with metastasis in patients with early invasive (pT1) colorectal carcinoma in colorectal polyps
Brown, Ian, Zammit, Andrew P., Bettington, Mark, Cooper, Caroline, Gill, Anthony J., Agoston, Agoston and Odze, Robert (2023). Pathological features associated with metastasis in patients with early invasive (pT1) colorectal carcinoma in colorectal polyps. Histopathology, 83 (4), 591-606. doi: 10.1111/his.14970
2023
Journal Article
Looking beyond workforce parity: addressing gender inequity in pathology
McKenzie, Catriona A., Gupta, Ruta, Jackett, Louise, Anderson, Lyndal, Chen, Vivien, Dahlstrom, Jane E., Dray, Michael, Farshid, Gelareh, Hemmings, Chris, Karim, Rooshdiya, Kench, James G., Klebe, Sonja, Kramer, Nicole, Kumarasinghe, Priyanthi, Maclean, Fiona, Morey, Adrienne, Nguyen, Minh Anh, O’Toole, Sandra, Rowbotham, Beverley, Salisbury, Elizabeth, Scolyer, Richard A., Stewart, Katie, Waring, Lynette, Cooper, Caroline L. and Cooper, Wendy A. (2023). Looking beyond workforce parity: addressing gender inequity in pathology. Pathology, 55 (6), 760-771. doi: 10.1016/j.pathol.2023.07.002
2023
Journal Article
Mapping the spatial proteome of head and neck tumors: key immune mediators and metabolic determinants in the tumor microenvironment
Jhaveri, Niyati, Ben Cheikh, Bassem, Nikulina, Nadezhda, Ma, Ning, Klymyshyn, Dmytro, DeRosa, James, Mihani, Ritu, Pratapa, Aditya, Kassim, Yasmin, Bommakanti, Sidharth, Shang, Olive, Berry, Shannon, Ihley, Nicholas, McLane, Michael, He, Yan, Zheng, Yi, Monkman, James, Cooper, Caroline, O'Byrne, Ken, Anand, Bhaskar, Prater, Michael, Basu, Subham, Hughes, Brett G. M., Kulasinghe, Arutha and Braubach, Oliver (2023). Mapping the spatial proteome of head and neck tumors: key immune mediators and metabolic determinants in the tumor microenvironment. GEN Biotechnology, 2 (5), 418-434. doi: 10.1089/genbio.2023.0029
2023
Conference Publication
High-plex spatial profiling of cutaneous squamous cell carcinoma to identify biomarkers associated with clinical outcomes: The cMIC study
Ladwa, R., Monkman, J., Sadeghirad, H., Cooper, C., Belz, G., Bowman, J., Schaider, H., Liu, H., Kulasinghe, A. and Porceddu, S. (2023). High-plex spatial profiling of cutaneous squamous cell carcinoma to identify biomarkers associated with clinical outcomes: The cMIC study. ESMO Congress 2023, Madrid, Spain, 20-24 October 2023. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.annonc.2023.09.2278
2023
Journal Article
A robust platform for integrative spatial multi‐omics analysis to map immune responses to SARS‐CoV‐2 infection in lung tissues
Tan, Xiao, Grice, Laura F., Tran, Minh, Mulay, Onkar, Monkman, James, Blick, Tony, Vo, Tuan, Almeida, Ana Clara, da Silva Motta, Jarbas, Fernandes de Moura, Karen, Machado‐Souza, Cleber, Souza‐Fonseca‐Guimaraes, Paulo, Baena, Cristina Pellegrino, de Noronha, Lucia, Guimaraes, Fernanda Simoes Fortes, Luu, Hung N., Drennon, Tingsheng, Williams, Stephen, Stern, Jacob, Uytingco, Cedric, Pan, Liuliu, Nam, Andy, Cooper, Caroline, Short, Kirsty, Belz, Gabrielle T., Souza‐Fonseca‐Guimaraes, Fernando, Kulasinghe, Arutha and Nguyen, Quan (2023). A robust platform for integrative spatial multi‐omics analysis to map immune responses to SARS‐CoV‐2 infection in lung tissues. Immunology, 170 (3), 401-418. doi: 10.1111/imm.13679
2022
Conference Publication
High-plex spatial proteomic profiling of immunotherapy response groups in head and neck cancer identifies tissue signatures associated with therapy response
Kulasinghe, Arutha, Sadeghirad, Habib, Liu, Ning, Monkman, James, Tan, Chin Wee, Cooper, Caroline, Church, Sarah, Schneider, Fabian, Thaagard, Jeppe, Mansfield, James, O’byrne, Kenneth, Davis, Melissa and Hughes, Brett (2022). High-plex spatial proteomic profiling of immunotherapy response groups in head and neck cancer identifies tissue signatures associated with therapy response. SITC 37th Annual Meeting (SITC 2022), Boston, MA United States, 8–12 November 2022. London, United Kingdom: BMJ Group. doi: 10.1136/jitc-2022-sitc2022.0117
2022
Journal Article
Occult small bowel adenocarcinoma in a Crohn disease stricture
Kaazan, Patricia, Slack, Timothy, Cooper, Caroline, Saad, Nivene and Martin, Neal (2022). Occult small bowel adenocarcinoma in a Crohn disease stricture. Internal Medicine Journal, 52 (6), 1093-1094. doi: 10.1111/imj.15811
2022
Journal Article
A multidisciplinary approach to rectal metastasis to the ovary: Krukenburg tumours
Le, Zhuang Hui Mark, Ng, Jessica Yan-Seen, Cooper, Caroline and Bloomfield, Ian (2022). A multidisciplinary approach to rectal metastasis to the ovary: Krukenburg tumours. ANZ Journal of Surgery, 92 (3) ans.17092, 583-585. doi: 10.1111/ans.17092
2022
Journal Article
Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures
Kulasinghe, Arutha, Tan, Chin Wee, dos Santos Miggiolaro, Anna Flavia Ribeiro, Monkman, James, SadeghiRad, Habib, Bhuva, Dharmesh D., da Silva Motta Junior, Jarbas, Vaz de Paula, Caroline Busatta, Nagashima, Seigo, Baena, Cristina Pellegrino, Souza-Fonseca-Guimaraes, Paulo, de Noronha, Lucia, McCulloch, Timothy, Rodrigues Rossi, Gustavo, Cooper, Caroline, Tang, Benjamin, Short, Kirsty R., Davis, Melissa J., Souza-Fonseca-Guimaraes, Fernando, Belz, Gabrielle T. and O'Byrne, Ken (2022). Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures. European Respiratory Journal, 59 (6) 2101881, 1-19. doi: 10.1183/13993003.01881-2021
2021
Journal Article
Germline ERBB3 mutation in familial non-small cell lung carcinoma: expanding ErbB’s role in oncogenesis
McInerney-Leo, Aideen M., Chew, Hui Yi, Inglis, Po-Ling, Leo, Paul J., Joseph, Shannon R., Cooper, Caroline L., Okano, Satomi, Hassall, Tim, Anderson, Lisa, Bowman, Rayleen V., Gattas, Michael, Harris, Jessica E., Marshall, Mhairi S., Shaw, Janet G., Wheeler, Lawrie, Yang, Ian A., Brown, Matthew A., Fong, Kwun M., Simpson, Fiona and Duncan, Emma L. (2021). Germline ERBB3 mutation in familial non-small cell lung carcinoma: expanding ErbB’s role in oncogenesis. Human Molecular Genetics, 30 (24), 2393-2401. doi: 10.1093/hmg/ddab172
2021
Journal Article
Endothelial cells are not productively infected by SARS‐CoV‐2
Schimmel, Lilian, Chew, Keng Yih, Stocks, Claudia J., Yordanov, Teodor E., Essebier, Patricia, Kulasinghe, Arutha, Monkman, James, Santos Miggiolaro, Anna Flavia Ribeiro, Cooper, Caroline, Noronha, Lucia, Schroder, Kate, Lagendijk, Anne Karine, Labzin, Larisa I., Short, Kirsty R. and Gordon, Emma J. (2021). Endothelial cells are not productively infected by SARS‐CoV‐2. Clinical and Translational Immunology, 10 (10) e1350, e1350. doi: 10.1002/cti2.1350
2021
Journal Article
A single-cell and spatially resolved atlas of human breast cancers
Wu, Sunny Z., Al-Eryani, Ghamdan, Roden, Daniel Lee, Junankar, Simon, Harvey, Kate, Andersson, Alma, Thennavan, Aatish, Wang, Chenfei, Torpy, James R., Bartonicek, Nenad, Wang, Taopeng, Larsson, Ludvig, Kaczorowski, Dominik, Weisenfeld, Neil I., Uytingco, Cedric R., Chew, Jennifer G., Bent, Zachary W., Chan, Chia-Ling, Gnanasambandapillai, Vikkitharan, Dutertre, Charles-Antoine, Gluch, Laurence, Hui, Mun N., Beith, Jane, Parker, Andrew, Robbins, Elizabeth, Segara, Davendra, Cooper, Caroline, Mak, Cindy, Chan, Belinda ... Swarbrick, Alexander (2021). A single-cell and spatially resolved atlas of human breast cancers. Nature Genetics, 53 (9), 1334-1347. doi: 10.1038/s41588-021-00911-1
2021
Journal Article
Targeting DNA damage response and replication stress in pancreatic cancer
Dreyer, Stephan B., Upstill-Goddard, Rosie, Paulus-Hock, Viola, Paris, Clara, Lampraki, Eirini-Maria, Dray, Eloise, Serrels, Bryan, Caligiuri, Giuseppina, Rebus, Selma, Plenker, Dennis, Galluzzo, Zachary, Brunton, Holly, Cunningham, Richard, Tesson, Mathias, Nourse, Craig, Bailey, Ulla-Maja, Jones, Marc D., Moran-Jones, Kim, Wright, Derek W., Duthie, Fraser, Oien, Karin, Evers, Lisa, McKay, Colin J., McGregor, Grant A., Gulati, Aditi, Brough, Rachel, Bajrami, Ilirjana, Pettitt, Stephan, Dziubinski, Michele L. ... Sansom, Owen J. (2021). Targeting DNA damage response and replication stress in pancreatic cancer. Gastroenterology, 160 (1), 362-377.e13. doi: 10.1053/j.gastro.2020.09.043
2020
Journal Article
Therapeutic implications of immune-profiling and EGFR expression in salivary gland carcinoma
Guazzo, Emily, Cooper, Caroline, Wilkinson, Lisa, Feng, Sophie, King, Brigid, Simpson, Fiona, Porceddu, Sandro, Panizza, Benedict and Coward, Jermaine I G (2020). Therapeutic implications of immune-profiling and EGFR expression in salivary gland carcinoma. Head and neck, 43 (3) hed.26529, 768-777. doi: 10.1002/hed.26529
Supervision
Availability
- Dr Caroline Cooper is:
- Available for supervision
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Media
Enquiries
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