Dr Rink-Jan Lohman
Dr

Rink-Jan Lohman

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Availability

Dr Rink-Jan Lohman is:
Available for supervision
Media expert

Qualifications

  • Bachelor (Honours) of Science (Advanced), University of Melbourne
  • Doctor of Philosophy, University of Melbourne

Research interests

  • Pharmacology

  • pharmacokinetics

  • inflammatory disease

  • peptides as disease modifying drugs

  • oral bioavailablity and transporters

Search Professor Rink-Jan Lohman’s works on UQ eSpace

55 works between 2002 and 2024
All (55) Journal Article (36) Book Chapter (2) Conference Publication (16) Other Outputs (1)

41 - 55 of 55 works

2012

Journal Article

Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110)

Suen, J. Y., Barry, G. D., Lohman, R. J., Halili, M. A., Cotterell, A. J., Le, G. T. and Fairlie, D. P. (2012). Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110). British Journal of Pharmacology, 165 (5), 1413-1423. doi: 10.1111/j.1476-5381.2011.01610.x

Modulating human proteinase activated receptor 2 with a novel antagonist (GB88) and agonist (GB110)

2012

Journal Article

Antagonism of protease-activated receptor 2 protects against experimental colitis.

Lohman, Rink-Jan, Cotterell, Adam J., Suen, Jacky, Liu, Ligong, Do, Anh T., Vesey, David A. and Fairlie, David P. (2012). Antagonism of protease-activated receptor 2 protects against experimental colitis.. Journal of Pharmacology and Experimental Therapeutics, 340 (2), 256-265. doi: 10.1124/jpet.111.187062

Antagonism of protease-activated receptor 2 protects against experimental colitis.

2011

Conference Publication

Novel agonists and antagonists for protease activated receptor 2

Yau, Annika M., Liu, Ligong, Reid, Robert C., Barry, Grant D., Suen, Jacky Y., Lohman, Rink-Jan, Le, Giang T., Cotterell, Adam and Fairlie, David P. (2011). Novel agonists and antagonists for protease activated receptor 2. National Meeting of the American Chemical Society (242nd, ACS, 2011), Denver, CO, U.S.A., 28 August-1 September 2011. WASHINGTON: AMER CHEMICAL SOC.

Novel agonists and antagonists for protease activated receptor 2

2011

Conference Publication

Towards orally bioavailable peptides and peptidomimetics

Fairlie, David P., Stoermer, Martin, Lucke, Andrew, Lohman, Rink-Jan, Liu, Ligong and Ruiz-Gomez, Gloria (2011). Towards orally bioavailable peptides and peptidomimetics. 241st National Meeting and Exposition of the American-Chemical-Society (ACS), Anaheim, CA, United States, 27-31 March 2011. Washington, DC, United States: American Chemical Society.

Towards orally bioavailable peptides and peptidomimetics

2010

Journal Article

Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in mice

Harrison, Rosemary S., Ruiz-Gomez, Gloria, Hill, Timothy A., Chow, Shiao Y., Shepherd, Nicholas E., Lohman, Rink-Jan, Abbenante, Giovanni, Hoang, Huy N. and Fairlie, David P. (2010). Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in mice. Journal of Medicinal Chemistry, 53 (23), 8400-8408. doi: 10.1021/jm101139f

Novel helix-constrained nociceptin derivatives are potent agonists and antagonists of ERK phosphorylation and thermal analgesia in mice

2009

Journal Article

A regulatory role for protease-activated receptor-2 in motivational learning in rats

Lohman, Rink-Jan, Jones, Nigel C., O’Brien, Terence J. and Cocks, Thomas M. (2009). A regulatory role for protease-activated receptor-2 in motivational learning in rats. Neurobiology of Learning and Memory, 92 (3), 301-309. doi: 10.1016/j.nlm.2009.03.010

A regulatory role for protease-activated receptor-2 in motivational learning in rats

2009

Conference Publication

Regulating protein and peptide activated GPCRs

Fairlie, David P., Madala, Praveen K., Stoermer, Martin J., Suen, Jacky, Barry, Grant and Lohman, Rink-Jan (2009). Regulating protein and peptide activated GPCRs. 229th National Meeting of the American Chemical Society, San Diego, California, 13-17 March 2005. Washington DC, United States: American Chemical Society.

Regulating protein and peptide activated GPCRs

2008

Journal Article

Protease-activated receptor-2 regulates trypsin expression in the brain and protects against seizures and epileptogenesis

Lohman, Rink-Jan, Cocks, Thomas M. and O'Brien, Terence J. (2008). Protease-activated receptor-2 regulates trypsin expression in the brain and protects against seizures and epileptogenesis. Neurobiology of Disease, 30 (1), 84-93. doi: 10.1016/j.nbd.2007.12.010

Protease-activated receptor-2 regulates trypsin expression in the brain and protects against seizures and epileptogenesis

2005

Journal Article

Validation of a method for localised microinjection of drugs into thalamic subregions in rats for epilepsy pharmacological studies

Lohman, Rink-Jan, Liu, Lige, Morris, Margaret and O’Brien, Terence J (2005). Validation of a method for localised microinjection of drugs into thalamic subregions in rats for epilepsy pharmacological studies. Journal of Neuroscience Methods, 146 (2), 191-197. doi: 10.1016/j.jneumeth.2005.02.008

Validation of a method for localised microinjection of drugs into thalamic subregions in rats for epilepsy pharmacological studies

2005

Conference Publication

Carbamazepine aggravates absence seizures in GAERS rats by acting on the ventrobasalthalamus via a GABA-A mediated mechanism

O'Brien, TJ, Liu, LG, Wallengren, L, Lohman, RJ and Morris, MJ (2005). Carbamazepine aggravates absence seizures in GAERS rats by acting on the ventrobasalthalamus via a GABA-A mediated mechanism. Joint Annual Meeting of the American-Epilepsy-Society/American-Clinical-Neurophsiology-Society, Washington Dc, Dec 02-06, 2005. OXFORD: BLACKWELL PUBLISHING.

Carbamazepine aggravates absence seizures in GAERS rats by acting on the ventrobasalthalamus via a GABA-A mediated mechanism

2004

Conference Publication

Specific fast oscillatory thalamocortical activity in brain slices in the gaers absence epilepsy model

Myers, DE, O'Brien, TJ, Reid, CA, Adams, BE, Lohman, RJ, Berkovic, S and Williams, DA (2004). Specific fast oscillatory thalamocortical activity in brain slices in the gaers absence epilepsy model. Annual Meeting of the American-Epilepsy-Society, New Orlands La, Dec 03-07, 2004. MALDEN: BLACKWELL PUBLISHING INC.

Specific fast oscillatory thalamocortical activity in brain slices in the gaers absence epilepsy model

2004

Conference Publication

Neuronal activation in the thalamic reticular nucleus correlates with seizure burden but not carbamazepine treatment in a rat model of absence epilepsy

Wallengren, CM, Morris, MJ, Li, S, Lohman, R, Jupp, B and OBrien, TJ (2004). Neuronal activation in the thalamic reticular nucleus correlates with seizure burden but not carbamazepine treatment in a rat model of absence epilepsy. Annual Meeting of the American-Epilepsy-Society, New Orlands La, Dec 03-07, 2004. MALDEN: BLACKWELL PUBLISHING INC.

Neuronal activation in the thalamic reticular nucleus correlates with seizure burden but not carbamazepine treatment in a rat model of absence epilepsy

2004

Conference Publication

Chronic low-dose corticosterone supplementation enhances acquired epileptogenesis in the rat amygdala kindling model of TLE

Taher, T, Salzberg, M, Morris, M, Lohman, RJ, Jupp, B and O'Brien, TJ (2004). Chronic low-dose corticosterone supplementation enhances acquired epileptogenesis in the rat amygdala kindling model of TLE. Annual Meeting of the American-Epilepsy-Society, New Orlands La, Dec 03-07, 2004. MALDEN: BLACKWELL PUBLISHING INC.

Chronic low-dose corticosterone supplementation enhances acquired epileptogenesis in the rat amygdala kindling model of TLE

2004

Conference Publication

GABA receptor subunit and neuropeptide-Y expression do not differ in brains of rats with genetic absence-like epilepsy compared with nonepileptic control rats

Li, S, Wallengren, CM, Lohman, R, Morris, MJ and OBrien, TJ (2004). GABA receptor subunit and neuropeptide-Y expression do not differ in brains of rats with genetic absence-like epilepsy compared with nonepileptic control rats. Annual Meeting of the American-Epilepsy-Society, New Orlands La, Dec 03-07, 2004. MALDEN: BLACKWELL PUBLISHING INC.

GABA receptor subunit and neuropeptide-Y expression do not differ in brains of rats with genetic absence-like epilepsy compared with nonepileptic control rats

2002

Journal Article

Action potential afterdepolarization mediated by a Ca2+-activated cation conductance in myenteric AH neurons

Vogal, F., Harvey, J. R., Lohman, R. -J. and Furness, J. B. (2002). Action potential afterdepolarization mediated by a Ca2+-activated cation conductance in myenteric AH neurons. Neuroscience, 115 (2), 375-393. doi: 10.1016/S0306-4522(02)00410-4

Action potential afterdepolarization mediated by a Ca2+-activated cation conductance in myenteric AH neurons

Past funding

  • 2015 - 2017
    Modulating Inflammatory and fibrogenic pathways in kidney disease using a novel antagonist of protease-activated receptor-2 (NHMRC Project Grant administered by MSHHS via the PA Hospital)
    Metro South Hospital and Health Service
    Open grant
  • 2015
    Targeting the progress of inflammatory bowel disease to cancer in mice
    UQ Early Career Researcher
    Open grant

Availability

Dr Rink-Jan Lohman is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Enquiries

Contact Dr Rink-Jan Lohman directly for media enquiries about:

  • animal ethics
  • animal research
  • anti-inflammatory
  • arthritis
  • colitis
  • drugs
  • inflammatory bowel disease
  • inflammatory disease
  • laboratory
  • mice
  • peptide
  • peptides
  • pharmacokinetics
  • pharmacology
  • ranting
  • rats
  • Science and technology

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