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Dr Dominic Guanzon
Dr

Dominic Guanzon

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Overview

Background

Dominic Guanzon is a research fellow at the University of Queensland within the Salomon Lab, and supported by the Lions Medical Research Foundation. His expertise lies in the fascinating realm of extracellular vesicles where he is the genomics leader. Dominic’s research involves developing nucleic acid blood tests to diagnose disease. His primary research focus is on predicting chemotherapy response in women diagnosed with ovarian cancer, specifically distinguishing between individuals who respond positively to chemotherapy and those resistant to it (chemoresistance).

Availability

Dr Dominic Guanzon is:
Available for supervision

Works

Search Professor Dominic Guanzon’s works on UQ eSpace

50 works between 2016 and 2025

1 - 20 of 50 works

2025

Journal Article

Extracellular vesicle miRNAs from three-dimensional ovarian cancer in vitro models and their implication in overall cancer survival

Godbole, Nihar, Lai, Andrew, Carrion, Flavio, Scholz-Romero, Katherin, Ravichandran, Akhilandeshwari, Kalita-de Croft, Priyakshi, McCart Reed, Amy E., Joshi, Vaibhavi, Lakhani, Sunil R., Masud, Mostafa Kamal, Yamauchi, Yusuke, Perrin, Lewis, Hooper, John, Bray, Laura, Guanzon, Dominic and Salomon, Carlos (2025). Extracellular vesicle miRNAs from three-dimensional ovarian cancer in vitro models and their implication in overall cancer survival. Heliyon, 11 (4) e42188, 1-19. doi: 10.1016/j.heliyon.2025.e42188

Extracellular vesicle miRNAs from three-dimensional ovarian cancer in vitro models and their implication in overall cancer survival

2025

Journal Article

Rapid and high-sensitivity screening of pregnancy complications by profiling circulating placental extracellular vesicles

Palma, Carlos, Masud, Mostafa Kamal, Guanzon, Dominic, Lai, Andrew, Razo, Melissa, Nakahara, Angela, Nair, Soumyalekshmi, Salas-Burgos, Alexis, Hossain, Md Shahriar A., Carrion, Flavio, Duncombe, Gregory, McIntyre, H. David, Handberg, Aase, Longo, Sherri, Yamauchi, Yusuke and Salomon, Carlos (2025). Rapid and high-sensitivity screening of pregnancy complications by profiling circulating placental extracellular vesicles. Science Advances, 11 (9) eadr4074, eadr4074. doi: 10.1126/sciadv.adr4074

Rapid and high-sensitivity screening of pregnancy complications by profiling circulating placental extracellular vesicles

2024

Journal Article

Comparing methylation levels assayed in GC-rich regions with current and emerging methods

Guanzon, Dominic, Ross, Jason P, Ma, Chenkai, Berry, Oliver and Liew, Yi Jin (2024). Comparing methylation levels assayed in GC-rich regions with current and emerging methods. BMC Genomics, 25 (1) 741. doi: 10.1186/s12864-024-10605-7

Comparing methylation levels assayed in GC-rich regions with current and emerging methods

2024

Journal Article

Enhancing precision targeting of ovarian cancer tumor cells in vivo through extracellular vesicle engineering

Alharbi, Mona, Lai, Andrew, Godbole, Nihar, Guanzon, Dominic, Nair, Soumyalekshmi, Zuñiga, Felipe, Quinn, Alexander, Yang, Mengliu, Wu, Sherry Y. and Salomon, Carlos (2024). Enhancing precision targeting of ovarian cancer tumor cells in vivo through extracellular vesicle engineering. International Journal of Cancer, 155 (8), 1510-1523. doi: 10.1002/ijc.35055

Enhancing precision targeting of ovarian cancer tumor cells in vivo through extracellular vesicle engineering

2024

Other Outputs

Extracellular vesicle miRNAs from three-dimensional ovarian cancer in vitro models and their implication in overall cancer survival.

Guanzon, Dominic (2024). Extracellular vesicle miRNAs from three-dimensional ovarian cancer in vitro models and their implication in overall cancer survival.. The University of Queensland. (Dataset) doi: 10.48610/712cbf3

Extracellular vesicle miRNAs from three-dimensional ovarian cancer in vitro models and their implication in overall cancer survival.

2024

Journal Article

High throughput surface epitope immunoaffinity isolation of extracellular vesicles and downstream analysis

Khanabdali, Ramin, Mandrekar, Michelle, Grygiel, Rick, Vo, Phuoc-an, Palma, Carlos, Nikseresht, Sara, Barton, Siena, Shojaee, Mozhgan, Bhuiyan, Sadman, Asari, Kartini, Belzer, Susan, Ansari, Khairul, Coward, Jermaine I., Perrin, Lewis, Hooper, John, Guanzon, Dominic, Lai, Andrew, Salomon, Carlos, Kershner, Kevin, Newton, Christine, Horejsh, Douglas and Rice, Gregory (2024). High throughput surface epitope immunoaffinity isolation of extracellular vesicles and downstream analysis. Biology Methods and Protocols, 9 (1) bpae032. doi: 10.1093/biomethods/bpae032

High throughput surface epitope immunoaffinity isolation of extracellular vesicles and downstream analysis

2024

Conference Publication

Changes in extracellular vesicle miRNAs from three-dimensional ovarian cancer cell models reflect physiological changes and cancer survival

Godbole, Nihar, Ravichandran, Akhilandeshwari, Guanzon, Dominic, Lai, Andrew, Carrion, Flavio, de Croft, Priyakshi Kalita, Perrin, Lewis, Hooper, John, Bray, Laura and Salomon, Carlos (2024). Changes in extracellular vesicle miRNAs from three-dimensional ovarian cancer cell models reflect physiological changes and cancer survival. American Association for Cancer Research Annual Meeting 2024, San Diego, CA United States, 5-10 April 2024. Philadelphia, PA United States: American Association for Cancer Research. doi: 10.1158/1538-7445.am2024-3386

Changes in extracellular vesicle miRNAs from three-dimensional ovarian cancer cell models reflect physiological changes and cancer survival

2024

Journal Article

Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches: Position paper

Welsh, Joshua A., Goberdhan, Deborah C. I., O'Driscoll, Lorraine, Buzas, Edit I., Blenkiron, Cherie, Bussolati, Benedetta, Cai, Houjian, Di Vizio, Dolores, Driedonks, Tom A. P., Erdbrugger, Uta, Falcon-Perez, Juan M., Fu, Qing-Ling, Hill, Andrew F., Lenassi, Metka, Lim, Sai Kiang, Mahoney, My G., Mohanty, Sujata, Moller, Andreas, Nieuwland, Rienk, Ochiya, Takahiro, Sahoo, Susmita, Torrecilhas, Ana C., Zheng, Lei, Zijlstra, Andries, Abuelreich, Sarah, Bagabas, Reem, Bergese, Paolo, Bridges, Esther M., Brucale, Marco ... Guanzon, Dominic (2024). Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches: Position paper. Journal of Extracellular Vesicles, 13 (2) e12404, 1-84. doi: 10.1002/jev2.12404

Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches: Position paper

2023

Other Outputs

INOVIQ manuscript

Guanzon, Dominic (2023). INOVIQ manuscript. The University of Queensland. (Dataset) doi: 10.48610/c517a74

INOVIQ manuscript

2023

Conference Publication

Effect of aspirin on the circulating extracellular vesicle proteomic profile in women at risk for preeclampsia

D'Crus, Angel Nilesh, Jellins, Jessica, Lai, Andrew, Guanzon, Dominic, Carrion, Flavio, Nair, Soumyalekshmi, Hyett, Jon and Salomon, Carlos (2023). Effect of aspirin on the circulating extracellular vesicle proteomic profile in women at risk for preeclampsia. 70th Annual Meeting of the Society for Reproductive Investigation (SRI), Brisbane, QLD, Australia, 21-25 March 2023. Heidelberg, Germany: Springer.

Effect of aspirin on the circulating extracellular vesicle proteomic profile in women at risk for preeclampsia

2023

Conference Publication

Unique tissue specific miRNA motifs in placenta and adipose tissue regulate changes in insulin sensitivity in healthy pregnancy and gestational diabetes

Nair, Soumyalekshmi S., Guanzon, Dominic, Jayabalan, Nanthini, Lai, Andrew, Scholz-Romero, Katherin, Carrion, Flavio, Lappas, Martha and Salomon, Carlos (2023). Unique tissue specific miRNA motifs in placenta and adipose tissue regulate changes in insulin sensitivity in healthy pregnancy and gestational diabetes. 70th Annual Meeting of the Society for Reproductive Investigation (SRI), Brisbane, QLD, Australia, 21-25 March 2023. Heidelberg, Germany: Springer.

Unique tissue specific miRNA motifs in placenta and adipose tissue regulate changes in insulin sensitivity in healthy pregnancy and gestational diabetes

2021

Journal Article

Extracellular vesicle-associated miRNAs are an adaptive response to gestational diabetes mellitus

Nair, Soumyalekshmi, Guanzon, Dominic, Jayabalan, Nanthini, Lai, Andrew, Scholz-Romero, Katherin, Kalita de Croft, Priyakshi, Ormazabal, Valeska, Palma, Carlos, Diaz, Emilio, McCarthy, Elizabeth A., Shub, Alexis, Miranda, Jezid, Gratacós, Eduard, Crispi, Fátima, Duncombe, Gregory, Lappas, Martha, McIntyre, H. David, Rice, Gregory and Salomon, Carlos (2021). Extracellular vesicle-associated miRNAs are an adaptive response to gestational diabetes mellitus. Journal of Translational Medicine, 19 (1) 360, 1-17. doi: 10.1186/s12967-021-02999-9

Extracellular vesicle-associated miRNAs are an adaptive response to gestational diabetes mellitus

2021

Journal Article

Partial Epithelial‐Mesenchymal Transition: Reduced miR‐4792 and miR‐146b‐5p Inversely Correlated with SIAH2 in Migrating Keratinocytes <i>in Vitro</i>

Wager, Lucas J., Guanzon, Dominic, Leavesley, David I., Thompson, Erik W. and Murray, Rachael Z. (2021). Partial Epithelial‐Mesenchymal Transition: Reduced miR‐4792 and miR‐146b‐5p Inversely Correlated with SIAH2 in Migrating Keratinocytes in Vitro. Experimental Dermatology, 30 (12), 1838-1839. doi: 10.1111/exd.14426

Partial Epithelial‐Mesenchymal Transition: Reduced miR‐4792 and miR‐146b‐5p Inversely Correlated with SIAH2 in Migrating Keratinocytes <i>in Vitro</i>

2021

Journal Article

Extracellular vesicle transmission of chemoresistance to ovarian cancer cells is associated with hypoxia-induced expression of glycolytic pathway proteins, and prediction of epithelial ovarian cancer disease recurrence

Alharbi, Mona, Lai, Andrew, Sharma, Shayna, Kalita-De Croft, Priyakshi, Godbole, Nihar, Campos, America, Guanzon, Dominic, Salas-Burgos, Alexis, Carrion, Flavio, Zuñiga, Felipe A., Perrin, Lewis, He, Yaowu, Pejovic, Tanja, Winters, Carmen, Morgan, Terry, Hooper, John D., Rice, Gregory E. and Salomon, Carlos (2021). Extracellular vesicle transmission of chemoresistance to ovarian cancer cells is associated with hypoxia-induced expression of glycolytic pathway proteins, and prediction of epithelial ovarian cancer disease recurrence. Cancers, 13 (14) 3388, 1-26. doi: 10.3390/cancers13143388

Extracellular vesicle transmission of chemoresistance to ovarian cancer cells is associated with hypoxia-induced expression of glycolytic pathway proteins, and prediction of epithelial ovarian cancer disease recurrence

2020

Journal Article

miRNa signature in small extracellular vesicles and their association with platinum resistance and cancer recurrence in ovarian cancer

Alharbi, Mona, Sharma, Shayna, Guanzon, Dominic, Lai, Andrew, Zuñiga, Felipe, Shiddiky, Muhammad J.A., Yamauchi, Yusuke, Salas-Burgos, Alexis, He, Yaowu, Pejovic, Tanja, Winters, Carmen, Morgan, Terry, Perrin, Lewis, Hooper, John D. and Salomon, Carlos (2020). miRNa signature in small extracellular vesicles and their association with platinum resistance and cancer recurrence in ovarian cancer. Nanomedicine: Nanotechnology, Biology, and Medicine, 28 102207, 102207. doi: 10.1016/j.nano.2020.102207

miRNa signature in small extracellular vesicles and their association with platinum resistance and cancer recurrence in ovarian cancer

2020

Journal Article

Protein profile changes in circulating placental extracellular vesicles in term and preterm births: a longitudinal study

Menon, Ramkumar, Debnath, Chirantan, Lai, Andrew, Guanzon, Dominic, Bhatnagar, Shinjini, Kshetrapal, Pallavi, Sheller-Miller, Samantha, Salomon, Carlos and The Garbh-Ini Study team (2020). Protein profile changes in circulating placental extracellular vesicles in term and preterm births: a longitudinal study. Endocrinology, 161 (4) bqaa009. doi: 10.1210/endocr/bqaa009

Protein profile changes in circulating placental extracellular vesicles in term and preterm births: a longitudinal study

2020

Journal Article

Regulation of glucose homeostasis by small extracellular vesicles in normal pregnancy and in gestational diabetes

James-Allan, Laura B., Rosario, Frederick J., Barner, Kelsey, Lai, Andrew, Guanzon, Dominic, McIntyre, H. David, Lappas, Martha, Powell, Theresa L., Salomon, Carlos and Jansson, Thomas (2020). Regulation of glucose homeostasis by small extracellular vesicles in normal pregnancy and in gestational diabetes. FASEB Journal, 34 (4) fj.201902522RR, 5724-5739. doi: 10.1096/fj.201902522RR

Regulation of glucose homeostasis by small extracellular vesicles in normal pregnancy and in gestational diabetes

2019

Journal Article

Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess

Tapia-Castillo, Alejandra, Guanzon, Dominic, Palma, Carlos, Lai, Andrew, Barros, Eric, Allende, Fidel, Vecchiola, Andrea, Fardella, Carlos E., Salomón, Carlos and Carvajal, Cristian A. (2019). Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess. Journal of Translational Medicine, 17 (1) 392, 392. doi: 10.1186/s12967-019-02143-8

Downregulation of exosomal miR-192-5p and miR-204-5p in subjects with nonclassic apparent mineralocorticoid excess

2019

Journal Article

DNA Methylation Cancer Biomarkers: Translation to the Clinic

Locke, Warwick J., Guanzon, Dominic, Ma, Chenkai, Liew, Yi Jin, Duesing, Konsta R., Fung, Kim Y.C. and Ross, Jason P. (2019). DNA Methylation Cancer Biomarkers: Translation to the Clinic. Frontiers in Genetics, 10, 1-22. doi: 10.3389/fgene.2019.01150

DNA Methylation Cancer Biomarkers: Translation to the Clinic

2019

Journal Article

Ovarian cancer-derived exosomes promote tumor metastasis in vivo an effect modulated by the invasiveness capacity of their originating cells

Alharbi, Mona, Lai, Andrew, Guanzon, Dominic, Palma, Carlos, Zuñiga, Felipe, Perrin, Lewis, He, Yaowu, Hooper, John D and Salomon, Carlos (2019). Ovarian cancer-derived exosomes promote tumor metastasis in vivo an effect modulated by the invasiveness capacity of their originating cells. Clinical Science, 133 (13), CS20190082-1419. doi: 10.1042/cs20190082

Ovarian cancer-derived exosomes promote tumor metastasis in vivo an effect modulated by the invasiveness capacity of their originating cells

Funding

Current funding

  • 2016 - 2026
    Tumour-derived exosome, a possible biomarker for the early detection of ovarian cancer
    Lions Medical Research Foundation
    Open grant

Supervision

Availability

Dr Dominic Guanzon is:
Available for supervision

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Supervision history

Current supervision

Media

Enquiries

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communications@uq.edu.au