Overview
Availability
- Dr Roger Bitencourt Varela is:
- Available for supervision
Qualifications
- Doctoral Diploma, Institution to be confirmed
Works
Search Professor Roger Bitencourt Varela’s works on UQ eSpace
2024
Journal Article
Exploring the impact of childhood maltreatment on epigenetic and brain-derived neurotrophic factor changes in bipolar disorder and healthy control
Possamai-Della, Taise, Peper-Nascimento, Jefté, Varela, Roger B., Daminelli, Thiani, Fries, Gabriel R., Ceretta, Luciane B., Juruena, Mario F., Quevedo, João and Valvassori, Samira S. (2024). Exploring the impact of childhood maltreatment on epigenetic and brain-derived neurotrophic factor changes in bipolar disorder and healthy control. European Archives of Psychiatry and Clinical Neuroscience. doi: 10.1007/s00406-024-01917-6
2024
Journal Article
Anti‐manic effect of deep brain stimulation of the ventral tegmental area in an animal model of mania induced by methamphetamine
Varela, Roger B., Boschen, Suelen L., Yates, Nathanael, Houghton, Tristan, Blaha, Charles D., Lee, Kendall H., Bennet, Kevin E., Kouzani, Abbas Z., Berk, Michael, Quevedo, João, Valvassori, Samira S. and Tye, Susannah J. (2024). Anti‐manic effect of deep brain stimulation of the ventral tegmental area in an animal model of mania induced by methamphetamine. Bipolar Disorders, 26 (4), 376-387. doi: 10.1111/bdi.13423
2024
Conference Publication
Exploring the relationship between childhood trauma and epigenetic alterations in bipolar disorder
Della, T. de Souza Possamai, Peper-Nascimento, J., Varela, R.B., Daminelli, T., Fries, G.R., Ceretta, L.B., Quevedo, J. and Valvassori, S.S. (2024). Exploring the relationship between childhood trauma and epigenetic alterations in bipolar disorder. 37th ECNP Congress 2024, Milan, Italy, 21-24 September 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.nsa.2024.104182
2023
Journal Article
Increasing dopamine synthesis in nigrostriatal circuits increases phasic dopamine release and alters dorsal striatal connectivity: implications for schizophrenia
Srivastav, Sunil, Cui, Xiaoying, Varela, Roger Bitencourt, Kesby, James P. and Eyles, Darryl (2023). Increasing dopamine synthesis in nigrostriatal circuits increases phasic dopamine release and alters dorsal striatal connectivity: implications for schizophrenia. Schizophrenia, 9 (1) 69, 69. doi: 10.1038/s41537-023-00397-2
2023
Journal Article
Haloperidol alters neurotrophic factors and epigenetic parameters in an animal model of schizophrenia induced by ketamine
Valvassori, Samira S., da Rosa, Richard T., Dal-Pont, Gustavo C., Varela, Roger B., Mastella, Gustavo A., Daminelli, Thiani, Fries, Gabriel R., Quevedo, Joao and Zugno, Alexandra I. (2023). Haloperidol alters neurotrophic factors and epigenetic parameters in an animal model of schizophrenia induced by ketamine. International Journal of Developmental Neuroscience, 83 (8), 691-702. doi: 10.1002/jdn.10296
2023
Journal Article
Antidepressant effect of sodium butyrate is accompanied by brain epigenetic modulation in rats subjected to early or late life stress
Valvassori, Samira Silva, Varela, Roger Bitencourt, Resende, Wilson Rodrigues, Della, Taise Possamai, Borba, Laura Araújo, Behenck, João Paulo, Réus, Gislaine Zilli and Quevedo, João (2023). Antidepressant effect of sodium butyrate is accompanied by brain epigenetic modulation in rats subjected to early or late life stress. Current Neurovascular Research, 20 (5), 586-598. doi: 10.2174/0115672026277345240115101852
2022
Journal Article
Enriched environment causes epigenetic changes in hippocampus and improves long-term cognitive function in sepsis
Corneo, Emily, Michels, Monique, Abatti, Mariane, Vieira, Andriele, Goncalves, Renata Casagrande, Gabriel, Filipe Fernandes, Borges, Heloisa, Goulart, Amanda, Matos, Natan da Silva, Dominguini, Diogo, Varela, Roger, Valvassori, Samira and Dal-Pizzol, Felipe (2022). Enriched environment causes epigenetic changes in hippocampus and improves long-term cognitive function in sepsis. Scientific Reports, 12 (1) 21092. doi: 10.1038/s41598-022-14660-6
2022
Journal Article
Contributions of epigenetic inheritance to the predisposition of major psychiatric disorders: Theoretical framework, evidence, and implications
Varela, Roger B., Cararo, José Henrique, Tye, Susannah J., Carvalho, Andre F., Valvassori, Samira S., Fries, Gabriel R. and Quevedo, João (2022). Contributions of epigenetic inheritance to the predisposition of major psychiatric disorders: Theoretical framework, evidence, and implications. Neuroscience and Biobehavioral Reviews, 135 104579, 104579. doi: 10.1016/j.neubiorev.2022.104579
2022
Book Chapter
Behavioral models of bipolar disorder
Varela, Roger B., Dal-Pont, Gustavo C., Quevedo, João and Valvassori, Samira S. (2022). Behavioral models of bipolar disorder. Biomarkers in Bipolar Disorders. (pp. 63-80) London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-821398-8.00015-1
2021
Journal Article
Effects of maternal folic acid supplementation on nuclear methyltransferase activity of adult rats subjected to an animal model of schizophrenia
Canever, Lara, Varela, Roger, Mastella, Gustavo A., Damazio, Louyse S., Valvassori, Samira S., Quevedo, Joao L. and Zugno, Alexandra (2021). Effects of maternal folic acid supplementation on nuclear methyltransferase activity of adult rats subjected to an animal model of schizophrenia. International Journal of Developmental Neuroscience, 81 (5), 461-467. doi: 10.1002/jdn.10109
2021
Journal Article
Ouabain induces memory impairment and alter the BDNF signaling pathway in an animal model of bipolar disorder: Cognitive and neurochemical alterations in BD model
Valvassori, Samira S., Dal-Pont, Gustavo C., Varela, Roger B., Resende, Wilson R., Gava, Fernanda F., Mina, Franciele G., Budni, Josiane and Quevedo, João (2021). Ouabain induces memory impairment and alter the BDNF signaling pathway in an animal model of bipolar disorder: Cognitive and neurochemical alterations in BD model. Journal of Affective Disorders, 282, 1195-1202. doi: 10.1016/j.jad.2020.12.190
2020
Journal Article
Role of epigenetic regulatory enzymes in animal models of mania induced by amphetamine and paradoxical sleep deprivation
Varela, Roger B., Resende, Wilson R., Dal-Pont, Gustavo C., Gava, Fernanda F., Nadas, Gabriella B., Tye, Susannah J., Andersen, Monica L., Quevedo, João and Valvassori, Samira S (2020). Role of epigenetic regulatory enzymes in animal models of mania induced by amphetamine and paradoxical sleep deprivation. European Journal of Neuroscience, 53 (2) ejn.14922, 649-662. doi: 10.1111/ejn.14922
2020
Journal Article
Increased inflammatory biomarkers and changes in biological rhythms in bipolar disorder: a case-control study
Bavaresco, Daniela, da Rosa, Maria Ines, Rodrigues Uggioni, Maria Laura, Ferraz, Sarah D., Pacheco, Tamires R., Zuehl Dal Toe, Helena C., da Silveira, Andressa P., Quadros, Luiz F. A., de Souza, Thiani Daminelli, Varela, Roger B., Vieira, Andriele A. S., Dal Pizzol, Felipe, Valvassori, Samira S. and Quevedo, Joao (2020). Increased inflammatory biomarkers and changes in biological rhythms in bipolar disorder: a case-control study. Journal of Affective Disorders, 271, 115-122. doi: 10.1016/j.jad.2020.03.073
2020
Journal Article
HDAC inhibitors reverse mania-like behavior and modulate epigenetic regulatory enzymes in an animal model of mania induced by Ouabain
Varela, Roger B., Resende, Wilson R., Dal-Pont, Gustavo C., Gava, Fernanda F., Tye, Susannah J., Quevedo, João and Valvassori, Samira S. (2020). HDAC inhibitors reverse mania-like behavior and modulate epigenetic regulatory enzymes in an animal model of mania induced by Ouabain. Pharmacology Biochemistry and Behavior, 193 172917, 172917. doi: 10.1016/j.pbb.2020.172917
2019
Journal Article
Efficacy of folic acid as an adjunct to lithium therapy on manic-like behaviors, oxidative stress and inflammatory parameters in an animal model of mania
Menegas, Samira, Dal-Pont, Gustavo C., Cararo, José H., Varela, Roger B., Aguiar-Geraldo, Jorge M., Possamai-Della, Taise, Andersen, Monica L., Quevedo, João and Valvassori, Samira S. (2019). Efficacy of folic acid as an adjunct to lithium therapy on manic-like behaviors, oxidative stress and inflammatory parameters in an animal model of mania. Metabolic Brain Disease, 35 (2), 413-425. doi: 10.1007/s11011-019-00503-3
2019
Journal Article
Coadministration of lithium and celecoxib reverses manic-like behavior and decreases oxidative stress in a dopaminergic model of mania induced in rats
Valvassori, Samira S., Tonin, Paula T., Dal-Pont, Gustavo C., Varela, Roger B., Cararo, José Henrique, Garcia, Abel Freitas, Gava, Fernanda F., Menegas, Samira, Soares, Jair C. and Quevedo, João (2019). Coadministration of lithium and celecoxib reverses manic-like behavior and decreases oxidative stress in a dopaminergic model of mania induced in rats. Translational Psychiatry, 9 (1) 297, 1-11. doi: 10.1038/s41398-019-0637-9
2019
Journal Article
Coadministration of lithium and celecoxib attenuates the behavioral alterations and inflammatory processes induced by amphetamine in an animal model of mania
Valvassori, Samira S., Dal-Pont, Gustavo C., Tonin, Paula T., Varela, Roger B., Ferreira, Camila L., Gava, Fernanda F., Andersen, Monica L., Soares, Jair C. and Quevedo, Joao (2019). Coadministration of lithium and celecoxib attenuates the behavioral alterations and inflammatory processes induced by amphetamine in an animal model of mania. Pharmacology, Biochemistry and Behavior, 183, 56-63. doi: 10.1016/j.pbb.2019.05.009
2019
Journal Article
Validation of the animal model of bipolar disorder induced by Ouabain: face, construct and predictive perspectives
Valvassori, Samira S., Dal-Pont, Gustavo C., Resende, Wilson R., Varela, Roger B., Lopes-Borges, Jessica, Cararo, Jose Henrique and Quevedo, Joao (2019). Validation of the animal model of bipolar disorder induced by Ouabain: face, construct and predictive perspectives. Translational Psychiatry, 9 (1) 158. doi: 10.1038/s41398-019-0494-6
2019
Journal Article
Tamoxifen has an anti-manic effect but not protect the brain against oxidative stress in an animal model of mania induced by ouabain
Dal-Pont, Gustavo C., Resende, Wilson R., Bianchini, Guilherme, Gava, Fernanda F., Peterle, Bruna R., Trajano, Kerolen S., Varela, Roger B., Quevedo, Joao and Valvassori, Samira S. (2019). Tamoxifen has an anti-manic effect but not protect the brain against oxidative stress in an animal model of mania induced by ouabain. Journal of Psychiatric Research, 113, 181-189. doi: 10.1016/j.jpsychires.2019.03.020
2019
Journal Article
Inhibition of GSK-3β on behavioral changes and oxidative stress in an animal model of mania
Dal-Pont, Gustavo C., Resende, Wilson R., Varela, Roger B., Menegas, Samira, Trajano, Kerolen S., Peterle, Bruna R., Quevedo, Joao and Valvassori, Samira S. (2019). Inhibition of GSK-3β on behavioral changes and oxidative stress in an animal model of mania. Molecular Neurobiology, 56 (4), 2379-2393. doi: 10.1007/s12035-018-1226-2
Funding
Past funding
Supervision
Availability
- Dr Roger Bitencourt Varela is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Prefrontal Mechanisms Regulating Striatal Dopamine During Persistent Effort
Associate Advisor
Other advisors: Associate Professor Susannah Tye
-
Doctor Philosophy
Prefrontal Mechanisms Regulating Striatal Dopamine During Persistent Effort
Associate Advisor
Other advisors: Associate Professor Susannah Tye
-
Doctor Philosophy
Prefrontal Mechanisms Regulating Striatal Dopamine During Persistent Effort
Associate Advisor
Other advisors: Associate Professor Susannah Tye
-
Doctor Philosophy
Immunometabolic Mechanisms of Mood Regulation
Associate Advisor
Other advisors: Associate Professor Susannah Tye
Media
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