Overview
Availability
- Dr Hanno Nel is:
- Available for supervision
Qualifications
- Bachelor of Science, North West University
- Bachelor (Honours) of Biochemistry, North West University
- Masters (Research) of Biochemistry, North West University
- Doctor of Philosophy, Stellenbosch University
Works
Search Professor Hanno Nel’s works on UQ eSpace
2018
Journal Article
Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development
Jansen, Diahann T. S. L., Ramnoruth, Nishta, Loh, Khai L., Rossjohn, Jamie, Reid, Hugh H., Nel, Hendrik J. and Thomas, Ranjeny (2018). Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development. Frontiers in Immunology, 9 (JAN) 8, 1-10. doi: 10.3389/fimmu.2018.00008
2018
Conference Publication
Pre-clinical clonally-expanded aggrecan89-103-specific CD4+T cells are a target for autoimmune arthritis prevention
Wehr, Pascale, Nel, Hendrik, Law, Soi Cheng, Jansen, Diahann, La Gruta, Nicole, Reid, Hugh, Rossjohn, Jamie and Thomas, Ranjeny (2018). Pre-clinical clonally-expanded aggrecan89-103-specific CD4+T cells are a target for autoimmune arthritis prevention. 2018 ACR/ARHP Annual Meeting, Chicago, Il United States, 19-24 October 2018. Hoboken, NJ United States: John Wiley & Sons.
2017
Journal Article
Dexamethasone and monophosphoryl lipid a induce a distinctive profile on monocyte-derived dendritic cells through transcriptional modulation of genes associated with essential processes of the immune response
Garcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Mehdi, Ahmed M., Nel, Hendrik J., Pesce, Barbara, Larrondo, Milton L., Aravena, Octavio, Molina, Mar-A C., Catalan, Diego, Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2017). Dexamethasone and monophosphoryl lipid a induce a distinctive profile on monocyte-derived dendritic cells through transcriptional modulation of genes associated with essential processes of the immune response. Frontiers in Immunology, 8 (OCT) 1350, 1350. doi: 10.3389/fimmu.2017.01350
2017
Journal Article
CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin
Overgaard, Nana H., Cruz, Jazmina L., Bridge, Jennifer A., Nel, Hendrik J., Frazer, Ian H., La Gruta, Nicole K., Blumenthal, Antje, Steptoe, Raymond J. and Wells, James W. (2017). CD4+CD8β+ double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin. Journal of Leukocyte Biology, 102 (3), 837-844. doi: 10.1189/jlb.1AB0217-065R
2017
Conference Publication
Antigen specific immunotherapy for autoimmune disease targeting dendritic cells
Bergot, Anne-Sophie, Talekar, Meghna, Nel, Hanno, Galea, Ryan, Harris, Mark, Hamilton-Williams, Emma and Thomas, Ranjeny (2017). Antigen specific immunotherapy for autoimmune disease targeting dendritic cells. 5th Annual Meeting of the International Cytokine and Interferon Society (ICIS), Kanazawa Japan, 29 October - 2 November 2017. London United Kingdom: Elsevier.
2017
Conference Publication
Mucosal-associated invariant T cells are an important source of TNF in rheumatoid arthritis
Jansen, Diahann, Klinken, Elizabeth, Nel, Hendrik, Law, Soi Cheng, Koppejan, Hester, Hameetman, Marjolijn, Liu, Ligong, Corbett, Alexandra, Eckle, Sidonia, Fairlie, David, Toes, Rene E. M., van Gaalen, Floris, Rossjohn, Jamie, McCluskey, James and Thomas, Ranjeny (2017). Mucosal-associated invariant T cells are an important source of TNF in rheumatoid arthritis. 2017 ACR/ARHP Annual Meeting, San Diego, California, 3-8 November 2017. Hoboken, NJ, United States: John Wiley & Sons.
2017
Conference Publication
Skin Migratory Dendritic Cells Targeted and Tolerized By Calcitriol-Peptide Liposomes Supress Antigen-Specific Autoreactive T Cell Expansion and Memory Differentiation to Regulate Autoimmune Arthritis
Galea, Ryan, Nel, Hendrik, Talekar, Meghna, Cole, Suzanne, Cochlin, Karyn, Hitchcock, Shannon, Zeng, Bijun, Yekollu, Suman, Rossjohn, Jamie, Reid, Hugh, Malaviya, Ravi, Shealy, Dave, O'Sullivan, Brendan and Thomas, Ranjeny (2017). Skin Migratory Dendritic Cells Targeted and Tolerized By Calcitriol-Peptide Liposomes Supress Antigen-Specific Autoreactive T Cell Expansion and Memory Differentiation to Regulate Autoimmune Arthritis. 2017 ACR/ARHP Pediatric Rheumatology Symposium, San Diego, California, 3-8 November 2017. Hoboken, NJ, United States: John Wiley & Sons.
2016
Journal Article
Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic features
Garcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Hoyos, Lorena, Morales, Rodrigo A., Mehdi, Ahmed M., Nel, Hendrik J., Soto, Lilian, Pesce, Barbara, Carmen Molina, Maria, Cuchacovich, Miguel, Larrondo, Milton L., Neira, Oscar, Francisco Catalan, Diego, Hilkens, Catharien M., Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2016). Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic features. Frontiers in Immunology, 7 (OCT) 458, 458. doi: 10.3389/fimmu.2016.00458
2016
Conference Publication
Heightened MAIT Cell Sensitivity to MR1 Ligands Could Impact Control of Dysbiosis in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis
Jansen, Diahann, Klinken, Elizabeth, Nel, Hendrik, Law, Soi Cheng, Benham, Helen, Cummins, Lisa, Brown, Matthew, Kenna, Tony, Liu, Ligong, Fairlie, David, Rossjohn, Jamie, Morrison, Mark, Thomas, Ranjeny, Cuiv, Paraic O., McCluskey, James and Corbett, Alexandra (2016). Heightened MAIT Cell Sensitivity to MR1 Ligands Could Impact Control of Dysbiosis in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis. 2016 ACR/ARHP Annual Meeting, Washington, DC, United States, 11-16 November 2016. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.39977
2016
Conference Publication
Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers the ability to modulate CD4+T cell responses
Garcia-Gonzalez, Paulina, Neira, Oscar, Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggy, Jaxaira, Hoyos, Lorena, Morales, Rodrigo, Ubilla-Olguin, Gabriela, Mehdi, Ahmed, Nel, Hendrik, Soto, Lilian, Pesce, Barbara, Carmen Molina, Maria, Cuchacovich, Miguel, Larrondo, Milton, Catalan, Diego, Hilkens, Catharien M., Thomas, Ranjeny, Verdugo, Ricardo and Aguillon, Juan C. (2016). Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers the ability to modulate CD4+T cell responses. Annual Meeting of the American-College-of-Rheumatology/Association-of-Rheumatology-Health-Professionals (ACR/ARHP), Washington, DC, United States, 11-16 November 2016. Hoboken, NJ, United States: John Wiley & Sons.
2016
Conference Publication
Alveolar macrophage in protracted bacterial bronchitis
Chen, Alice, Pena, Olga, Nel, Hanno, Pizzuto, Susan, Petsky, Helen, Gardiner, Samantha, Yerkovich, Stephanie, Baines, Katie, Gibson, Peter, Hodge, Greg, Hodge, Sandra, Buntain, Helen, Chang, Anne and Upham, John (2016). Alveolar macrophage in protracted bacterial bronchitis. ERS International Congress 2016, London, United Kingdom, 2016. Lausanne, Switzerland: European Respiratory Society. doi: 10.1183/13993003.congress-2016.PA3977
2016
Conference Publication
Dexamethasone and MPLA treatment of monocyte-derived dendritic cells from rheumatoid arthritis patients induce transcriptional modulation of genes related to cell recruitment, signaling and metabolism
Garcia-Gonzalez, P. A., Schinnerling, K., Sepulveda, A., Ubilla-Olguin, G., Soto, L., Neira, O., Medhi, A. M., Nel, H. J., Catalan, D., Thomas, R., Verdugo, R. A. and Aguillon, J. C. (2016). Dexamethasone and MPLA treatment of monocyte-derived dendritic cells from rheumatoid arthritis patients induce transcriptional modulation of genes related to cell recruitment, signaling and metabolism. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley.
2016
Conference Publication
Collagen specific CD4+T-cells restricted by HLA-DRB1*0101 are selected into the repertoire and expand in disease in mice and patients with inflammatory arthritis
Jansen, D. T. S. L., Nel, H. J., Ramnoruth, N., Tesiram, J., Nagl, L., Benham, H., Scally, S., Reed, H. H., Rossjohn, J. and Thomas, R. (2016). Collagen specific CD4+T-cells restricted by HLA-DRB1*0101 are selected into the repertoire and expand in disease in mice and patients with inflammatory arthritis. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200
2016
Conference Publication
CD4(+)CD8(+) double-positive T-cells regulate CD8(+) single-positive T cell function in the skin
Cruz, Gonzalez J. L., Overgaard, N. H., Bridge, J. A., Jung, J. -W, He, J., Nel, H. J., Watson, K., Frazer, I. H., La Gruta, N. L., Steptoe, R. J. and Wells, J. W. (2016). CD4(+)CD8(+) double-positive T-cells regulate CD8(+) single-positive T cell function in the skin. International Congress of Immunology (ICI), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200
2016
Conference Publication
Oligoclonally expanded CD4+T cells recognising citrulinated vimentin in peripheral blood of rheumatoid arthritis patients
Law, S. C., Nel, H. J., Scally, S. W., Mehdi, A., Le Cao, K. -A, Rossjohn, J., Reid, H. H., La Gruta, N. L. and Thomas, R. (2016). Oligoclonally expanded CD4+T cells recognising citrulinated vimentin in peripheral blood of rheumatoid arthritis patients. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200
2015
Conference Publication
Profiling at the Single-Cell Level Reveals Evidence for Antigen-Driven Oligoclonal Expansion of Citrullinated Vimentin-Specific CD4+T Cells in Peripheral Blood of Rheumatoid Arthritis (RA) Patients
Law, Soi Cheng, Nel, Hendrik, Rossjohn, Jamie, Reid, Hugh H., La Gruta, Nicole L. and Thomas, Ranjeny (2015). Profiling at the Single-Cell Level Reveals Evidence for Antigen-Driven Oligoclonal Expansion of Citrullinated Vimentin-Specific CD4+T Cells in Peripheral Blood of Rheumatoid Arthritis (RA) Patients. Annual Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), San Francisco Ca, Nov 06-11, 2015. HOBOKEN: WILEY-BLACKWELL.
2015
Journal Article
Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients
Benham, Helen, Nel, Hendrik J., Law, Soi Cheng, Mehdi, Ahmed M., Street, Shayna, Ramnoruth, Nishta, Pahau, Helen, Lee, Bernett T., Ng, Jennifer, Brunck, Marion E. G., Hyde, Claire, Trouw, Leendert A., Dudek, Nadine L., Purcell, Anthony W., O'Sullivan, Brendan J., Connolly, John E., Paul, Sanjoy K., Le Cao, Kim-Anh and Thomas, Ranjeny (2015). Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients. Science Translational Medicine, 7 (290) 290ra87, 290ra87.1-290ra87.11. doi: 10.1126/scitranslmed.aaa9301
2015
Conference Publication
Profiling the TCR repertoire in the Rheumatoid Arthritis (RA) Autoantigen-Specific Cd4+T-Cells At the Single-Cell Level
Law, S., Rossjohn, J., Nel, H., La Gruta, N., Reid, H. and Thomas, R. (2015). Profiling the TCR repertoire in the Rheumatoid Arthritis (RA) Autoantigen-Specific Cd4+T-Cells At the Single-Cell Level. Australian Rheumatology Associationin conjunction with Rheumatology Health Professionals Association, 56th Annual Scientific Meeting, Adelaide, South Australia, 23–26 May 2015. Richmond, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/imj.12752
2014
Journal Article
Mycobacterium bovis BCG infection severely delays Trichuris muris expulsion and co-infection suppresses immune responsiveness to both pathogens
Nel, Hendrik J., du Plessis, Nelita, Kleynhans, Leanie, Loxton, Andre G., van Helden, Paul D. and Walzl, Gerhard (2014). Mycobacterium bovis BCG infection severely delays Trichuris muris expulsion and co-infection suppresses immune responsiveness to both pathogens. BMC Microbiology, 14 (1) 9, 1-13. doi: 10.1186/1471-2180-14-9
2014
Conference Publication
Multiple Mechanisms of Tolerance Characterize the Immune Response to Autologous Modified Dendritic Cells Exposed to Citrullinated Peptides in Patients with Rheumatoid Arthritis.
Law, Soi-Cheng, Nel, Hendrik, Mehdi, Ahmed, Le Cao, Kim-Anh and Thomas, Ranjeny (2014). Multiple Mechanisms of Tolerance Characterize the Immune Response to Autologous Modified Dendritic Cells Exposed to Citrullinated Peptides in Patients with Rheumatoid Arthritis.. 2014 ACR/ARHP Annual Meeting, Boston, MA United States, 14-19 November 2014. Hoboken, NJ United States: John Wiley and Sons. doi: 10.1002/art.38914
Supervision
Availability
- Dr Hanno Nel is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Islet-specific T cell responses in type 1 diabetes
Associate Advisor
Other advisors: Dr Ahmed Mehdi, Professor Emma Hamilton-Williams, Professor Ranjeny Thomas
-
Doctor Philosophy
Immunogenic epitopes of the TSH receptor in Graves' disease
Associate Advisor
Other advisors: Professor Ranjeny Thomas
-
Doctor Philosophy
Identifying immune specific epitopes of TSH receptor in Graves¿ disease
Associate Advisor
Other advisors: Professor Ranjeny Thomas
Completed supervision
-
2023
Doctor Philosophy
Defining the role of T cells in Rheumatoid Arthritis
Associate Advisor
Other advisors: Professor Ranjeny Thomas
Media
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