Overview
Availability
- Dr Esteban Cruz Gonzalez is:
- Available for supervision
Qualifications
- Doctor of Philosophy, University of Sydney
Works
Search Professor Esteban Cruz Gonzalez’s works on UQ eSpace
2024
Journal Article
Proteostasis as a fundamental principle of Tau immunotherapy
Cruz, Esteban, Nisbet, Rebecca M, Padmanabhan, Pranesh, van Waardenberg, Ashley J, Graham, Mark E, Nkajja, Godfrey, Tapaswi, Swara, Connor, Bradley J, Robinson, Phil and Götz, Jürgen (2024). Proteostasis as a fundamental principle of Tau immunotherapy. Brain, 148 (1), 168-184. doi: 10.1093/brain/awae254
2024
Journal Article
Single-molecule imaging of Tau reveals how phosphorylation affects its movement and confinement in living cells
Padmanabhan, Pranesh, Kneynsberg, Andrew, Cruz, Esteban, Briner, Adam and Götz, Jürgen (2024). Single-molecule imaging of Tau reveals how phosphorylation affects its movement and confinement in living cells. Molecular Brain, 17 (1) 7, 7. doi: 10.1186/s13041-024-01078-6
2023
Journal Article
Break and accelerator—The mechanics of Tau (and amyloid) toxicity
Cruz, Esteban, Nisbet, Rebecca M. and Götz, Jürgen (2023). Break and accelerator—The mechanics of Tau (and amyloid) toxicity. Cytoskeleton, 81 (1), 24-29. doi: 10.1002/cm.21781
2022
Journal Article
Opportunities and challenges in delivering biologics for Alzheimer's disease by low-intensity ultrasound
Chen, Liyu, Cruz, Esteban, Oikari, Lotta E., Padmanabhan, Pranesh, Song, Jae and Götz, Jürgen (2022). Opportunities and challenges in delivering biologics for Alzheimer's disease by low-intensity ultrasound. Advanced Drug Delivery Reviews, 189 114517, 1-18. doi: 10.1016/j.addr.2022.114517
2022
Journal Article
Ultrasound-mediated delivery of novel tau-specific monoclonal antibody enhances brain uptake but not therapeutic efficacy
Bajracharya, Rinie, Cruz, Esteban, Götz, Jürgen and Nisbet, Rebecca M. (2022). Ultrasound-mediated delivery of novel tau-specific monoclonal antibody enhances brain uptake but not therapeutic efficacy. Journal of Controlled Release, 349, 634-648. doi: 10.1016/j.jconrel.2022.07.026
2022
Journal Article
Single‐molecule imaging reveals Tau trapping at nanometer‐sized dynamic hot spots near the plasma membrane that persists after microtubule perturbation and cholesterol depletion
Padmanabhan, Pranesh, Kneynsberg, Andrew, Cruz, Esteban, Amor, Rumelo, Sibarita, Jean‐Baptiste and Götz, Jürgen (2022). Single‐molecule imaging reveals Tau trapping at nanometer‐sized dynamic hot spots near the plasma membrane that persists after microtubule perturbation and cholesterol depletion. The EMBO Journal, 41 (19) e111265, 1-16. doi: 10.15252/embj.2022111265
2022
Journal Article
Claudin-5 binder enhances focused ultrasound-mediated opening in an in vitro blood-brain barrier model
Chen, Liyu, Sutharsan, Ratneswary, Lee, Jonathan LF, Cruz, Esteban, Asnicar, Blaise, Palliyaguru, Tishila, Wasielewska, Joanna M, Gaudin, Arnaud, Song, Jae, Leinenga, Gerhard and Götz, Jürgen (2022). Claudin-5 binder enhances focused ultrasound-mediated opening in an in vitro blood-brain barrier model. Theranostics, 12 (5), 1952-1970. doi: 10.7150/thno.65539
2021
Journal Article
Glycan profile analysis of engineered trastuzumab with rationally added glycosylation sequons presents significantly increased glycan complexity
Cruz, Esteban, Sifniotis, Vicki, Sumer-Bayraktar, Zeynep, Reslan, Mouhamad, Wilkinson-White, Lorna, Cordwell, Stuart and Kayser, Veysel (2021). Glycan profile analysis of engineered trastuzumab with rationally added glycosylation sequons presents significantly increased glycan complexity. Pharmaceutics, 13 (11) 1747, 1747. doi: 10.3390/pharmaceutics13111747
2021
Journal Article
Therapeutic ultrasound as a treatment modality for physiological and pathological ageing including Alzheimer’s disease
Götz, Jürgen, Richter-Stretton, Gina and Cruz, Esteban (2021). Therapeutic ultrasound as a treatment modality for physiological and pathological ageing including Alzheimer’s disease. Pharmaceutics, 13 (7) 1002, 1002. doi: 10.3390/pharmaceutics13071002
2021
Book Chapter
Drug targets for biologics
Lai, Felcia, Hawkins, Bryson A., Cruz, Esteban, Hanrahan, Jane R., Groundwater, Paul W. and Hibbs, David E. (2021). Drug targets for biologics. Biologics, biosimilars, and biobetters: an introduction for pharmacists, physicians, and other health practitioners. (pp. 195-212) edited by Iqbal Ramzan. Hoboken, NJ United States: Wiley. doi: 10.1002/9781119564690.ch5
2020
Journal Article
Enhancing the stability of adalimumab by engineering additional glycosylation motifs
Reslan, Mouhamad, Sifniotis, Vicki, Cruz, Esteban, Sumer-Bayraktar, Zeynep, Cordwell, Stuart and Kayser, Veysel (2020). Enhancing the stability of adalimumab by engineering additional glycosylation motifs. International Journal of Biological Macromolecules, 158, 189-196. doi: 10.1016/j.ijbiomac.2020.04.147
2019
Journal Article
Structural biology workflow for the expression and characterization of functional human sodium glucose transporter type 1 in Pichia pastoris
Suades, Albert, Alcaraz, Antonio, Cruz, Esteban, Álvarez-Marimon, Elena, Whitelegge, Julian P., Manyosa, Joan, Cladera, Josep and Perálvarez-Marín, Alex (2019). Structural biology workflow for the expression and characterization of functional human sodium glucose transporter type 1 in Pichia pastoris. Scientific Reports, 9 (1) 1203. doi: 10.1038/s41598-018-37445-2
2019
Journal Article
Current advancements in addressing key challenges of therapeutic antibody design, manufacture, and formulation
Sifniotis, Vicki, Cruz, Esteban, Eroglu, Barbaros and Kayser, Veysel (2019). Current advancements in addressing key challenges of therapeutic antibody design, manufacture, and formulation. Antibodies, 8 (2) 36, 36. doi: 10.3390/antib8020036
2019
Journal Article
Synthesis and enhanced cellular uptake in vitro of anti-HER2 multifunctional gold nanoparticles
Cruz, Esteban and Kayser, Veysel (2019). Synthesis and enhanced cellular uptake in vitro of anti-HER2 multifunctional gold nanoparticles. Cancers, 11 (6) 870, 870. doi: 10.3390/cancers11060870
2019
Journal Article
Monoclonal antibody therapy of solid tumors: clinical limitations and novel strategies to enhance treatment efficacy
Cruz, Esteban and Kayser, Veysel (2019). Monoclonal antibody therapy of solid tumors: clinical limitations and novel strategies to enhance treatment efficacy. Biologics: Targets and Therapy, 13, 33-51. doi: 10.2147/BTT.S166310
2018
Journal Article
Demonstration of in vitro host-guest complex formation and safety of para-sulfonatocalix[8]arene as a delivery vehicle for two antibiotic drugs
Moussa, Yvonne E., Ong, Yu Qing Elysia, Perry, John D., Cheng, Zhengqi, Kayser, Veysel, Cruz, Esteban, Kim, Ryung Rae, Sciortino, Natasha and Wheate, Nial J. (2018). Demonstration of in vitro host-guest complex formation and safety of para-sulfonatocalix[8]arene as a delivery vehicle for two antibiotic drugs. Journal of Pharmaceutical Sciences, 107 (12), 3105-3111. doi: 10.1016/j.xphs.2018.08.016
2018
Journal Article
Site-specific glycosylation profile of influenza A (H1N1) hemagglutinin through tandem mass spectrometry
Cruz, Esteban, Cain, Joel, Crossett, Ben and Kayser, Veysel (2018). Site-specific glycosylation profile of influenza A (H1N1) hemagglutinin through tandem mass spectrometry. Human Vaccines and Immunotherapeutics, 14 (3), 508-517. doi: 10.1080/21645515.2017.1377871
2017
Journal Article
The state-of-play and future of antibody therapeutics
Elgundi, Zehra, Reslan, Mouhamad, Cruz, Esteban, Sifniotis, Vicki and Kayser, Veysel (2017). The state-of-play and future of antibody therapeutics. Advanced Drug Delivery Reviews, 122, 2-19. doi: 10.1016/j.addr.2016.11.004
2017
Journal Article
Laboratory scale production and purification of a therapeutic antibody
Elgundi, Zehra, Sifniotis, Vicki, Reslan, Mouhamad, Cruz, Esteban and Kayser, Veysel (2017). Laboratory scale production and purification of a therapeutic antibody. Journal of Visualized Experiments, 2017 (119) e55153. doi: 10.3791/55153
Funding
Current funding
Supervision
Availability
- Dr Esteban Cruz Gonzalez is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Dissecting the molecular mechanisms of autophagy induction in neurons following application of focused ultrasound.
Associate Advisor
Other advisors: Professor Jurgen Götz
-
Doctor Philosophy
Feasibility study of using low-intensity focused ultrasound as a novel modality for the delivery of genetic material such as expression vectors and gene editing reagents to the mouse brain
Associate Advisor
Other advisors: Professor Jurgen Götz
-
Doctor Philosophy
Pathomechanistic and therapeutic studies in Alzheimer disease with a focus on the role of the blood-brain barrier
Associate Advisor
Other advisors: Professor Jurgen Götz
Media
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