Overview
Background
Dr Natalee Newton is a molecular and structural virologist passionate about understanding the structure of flaviviruses and using these findings for the design and development of vaccines and therapeutics. Dr Newton completed her PhD at SCMB, UQ, developing a chimeric system to safely study the structure, using cryo-EM, of highly pathogenic tick- and mosquito-borne flaviviruses such as West Nile virus, dengue virus and tick-borne encephalitis virus. She also investigated the maturation and virion structure of an insect-specific flavivirus, which changed the way we view flavivirus architecture. Following this, Dr Newton began her post doc at SCMB UQ where she is now assessing the structure and immune profile of ancestral and sylvatic flaviviruses.
Availability
- Dr Natalee Newton is:
- Available for supervision
Qualifications
- Bachelor of Science, The University of Queensland
- Bachelor (Honours) of Science (Advanced), The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research interests
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Structure of pathogenic flaviviruses
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Vaccine design for dengue, Japanese encephalitis virus and other pathogenic flaviviruses
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Tick-borne flaviviruses
Works
Search Professor Natalee Newton’s works on UQ eSpace
2020
Journal Article
Novel monoclonal antibodies against Australian strains of negeviruses and insights into virus structure, replication and host -restriction
Colmant, Agathe M. G., O'Brien, Caitlin A., Newton, Natalee D., Watterson, Daniel, Hardy, Joshua, Coulibaly, Fasséli, Bielefeldt-Ohmann, Helle, Warrilow, David, Huang, Bixing, Paramitha, Devina, Harrison, Jessica J., Hall, Roy A. and Hobson-Peters, Jody (2020). Novel monoclonal antibodies against Australian strains of negeviruses and insights into virus structure, replication and host -restriction. Journal of General Virology, 101 (4), 440-452. doi: 10.1099/jgv.0.001388
2019
Journal Article
A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus
Hobson-Peters, Jody, Harrison, Jessica J., Watterson, Daniel, Hazlewood, Jessamine E., Vet, Laura J., Newton, Natalee D., Warrilow, David, Colmant, Agathe M. G., Taylor, Carmel, Huang, Bixing, Piyasena, Thisun B. H., Chow, Weng Kong, Setoh, Yin Xiang, Tang, Bing, Nakayama, Eri, Yan, Kexin, Amarilla, Alberto A., Wheatley, Sarah, Moore, Peter R., Finger, Mitchell, Kurucz, Nina, Modhiran, Naphak, Young, Paul R., Khromykh, Alexander A., Bielefeldt-Ohmann, Helle, Suhrbier, Andreas and Hall, Roy A. (2019). A recombinant platform for flavivirus vaccines and diagnostics using chimeras of a new insect-specific virus. Science Translational Medicine, 11 (522) eaax7888, 1-15. doi: 10.1126/scitranslmed.aax7888
2019
Journal Article
Chimeric viruses of the insect-specific flavivirus Palm Creek with structural proteins of vertebrate-infecting flaviviruses identify barriers to replication of insect-specific flaviviruses in vertebrate cells
Piyasena, Thisun B H, Newton, Natalee D, Hobson-Peters, Jody, Vet, Laura J, Setoh, Yin X, Bielefeldt-Ohmann, Helle, Khromykh, Alexander A and Hall, Roy A (2019). Chimeric viruses of the insect-specific flavivirus Palm Creek with structural proteins of vertebrate-infecting flaviviruses identify barriers to replication of insect-specific flaviviruses in vertebrate cells. The Journal of general virology, 100 (11), 1580-1586. doi: 10.1099/jgv.0.001326
2019
Journal Article
Author Correction: Infectious DNAs derived from insect-specific flavivirus genomes enable identification of pre- and post-entry host restrictions in vertebrate cells
Piyasena, Thisun B. H., Setoh, Yin X., Hobson-Peters, Jody, Newton, Natalee D., Bielefeldt-Ohmann, Helle, McLean, Breeanna J., Vet, Laura J., Khromykh, Alexander A. and Hall, Roy A. (2019). Author Correction: Infectious DNAs derived from insect-specific flavivirus genomes enable identification of pre- and post-entry host restrictions in vertebrate cells. Scientific Reports, 9 (1) 8431, 8431. doi: 10.1038/s41598-019-44657-7
2018
Journal Article
The taxonomy of an Australian nodavirus isolated from mosquitoes
Warrilow, David, Huang, Bixing, Newton, Natalee D., Harrison, Jessica J., Johnson, Karyn N., Chow, Weng Kong, Hall, Roy A. and Hobson-Peters, Jody (2018). The taxonomy of an Australian nodavirus isolated from mosquitoes. PLoS One, 13 (12) e0210029, 1-9. doi: 10.1371/journal.pone.0210029
2018
Journal Article
The recently identified flavivirus Bamaga virus is transmitted horizontally by Culex mosquitoes and interferes with West Nile virus replication in vitro and transmission in vivo
Colmant, Agathe M. G., Hall-Mendelin, Sonja, Ritchie, Scott A., Bielefeldt-Ohmann, Helle, Harrison, Jessica J., Newton, Natalee D., O’Brien, Caitlin A., Cazier, Chris, Johansen, Cheryl A., Hobson-Peters, Jody, Hall, Roy A. and van den Hurk, Andrew F. (2018). The recently identified flavivirus Bamaga virus is transmitted horizontally by Culex mosquitoes and interferes with West Nile virus replication in vitro and transmission in vivo. PLoS Neglected Tropical Diseases, 12 (10) e0006886, e0006886. doi: 10.1371/journal.pntd.0006886
2017
Journal Article
Infectious DNAs derived from insect-specific flavivirus genomes enable identification of pre- and post-entry host restrictions in vertebrate cells
Piyasena, Thisun B. H. , Setoh, Yin X., Hobson-Peters, Jody, Newton, Natalee D. , Bielefeldt-Ohmann, Helle, McLean, Breeanna J. , Vet, Laura J. , Khromykh, Alexander A. and Hall, Roy A. (2017). Infectious DNAs derived from insect-specific flavivirus genomes enable identification of pre- and post-entry host restrictions in vertebrate cells. Scientific Reports, 7 (1) 2940, 2940.1-2940.11. doi: 10.1038/s41598-017-03120-1
2017
Journal Article
Discovery and characterisation of castlerea virus, a new species of Negevirus isolated in Australia
O'Brien, Caitlin A., McLean, Breeanna J., Colmant, Agathe M. G., Harrison, Jessica J., Hall-Mendelin, Sonja, van den Hurk, Andrew F., Johansen, Cheryl A., Watterson, Daniel, Bielefeldt-Ohmann, Helle, Newton, Natalee D., Schulz, Benjamin L., Hall, Roy A. and Hobson-Peters, Jody (2017). Discovery and characterisation of castlerea virus, a new species of Negevirus isolated in Australia. Evolutionary Bioinformatics, 13, 1176934317691269. doi: 10.1177/1176934317691269
2017
Journal Article
Commensal viruses of mosquitoes: Host restriction, transmission, and interaction with arboviral pathogens
Hall, Roy A., Bielefeldt-Ohmann, Helle, McLean, Breeanna J., O'Brien, Caitlin A., Colmant, Agathe M.G., Piyasena, Thisun B.H., Harrison, Jessica J., Newton, Natalee D., Barnard, Ross T., Prow, Natalie A., Deerain, Joshua M., Mah, Marcus G.K.Y. and Hobson-Peters, Jody (2017). Commensal viruses of mosquitoes: Host restriction, transmission, and interaction with arboviral pathogens. Evolutionary Bioinformatics, 12 (Suppl 2), 35-44. doi: 10.4137/EBO.S40740
Funding
Current funding
Supervision
Availability
- Dr Natalee Newton is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Mechanisms of host restriction underpinning the safety and efficacy of novel chimeric flaviviral vaccines
Associate Advisor
Other advisors: Professor Alexander Khromykh, Associate Professor Jody Peters
Media
Enquiries
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