Overview
Availability
- Dr Kelly Walton is:
- Available for supervision
Works
Search Professor Kelly Walton’s works on UQ eSpace
2025
Journal Article
Gene therapy with feline anti-Müllerian hormone analogs disrupts folliculogenesis and induces pregnancy loss in female domestic cats
Stocker, William A., Olenick, Lauren, Maskey, Shreya, Skrombolas, Denise, Luan, Haitong, Harrison, Sophie G., Wilson, Matt, Traas, Anne, Heffernan, Mark, Busfield, Samantha, Walton, Kelly L. and Harrison, Craig A. (2025). Gene therapy with feline anti-Müllerian hormone analogs disrupts folliculogenesis and induces pregnancy loss in female domestic cats. Nature Communications, 16 (1) 1668. doi: 10.1038/s41467-025-56924-5
2025
Journal Article
Muscle-derived myostatin is a major endocrine driver of follicle-stimulating hormone synthesis
Ongaro, Luisina, Zhou, Xiang, Wang, Ying, Schultz, Hailey, Zhou, Ziyue, Buddle, Evan R. S., Brûlé, Emilie, Lin, Yeu-Farn, Schang, Gauthier, Hagg, Adam, Castonguay, Roselyne, Liu, Yewei, Su, Gloria H., Seidah, Nabil G., Ray, Kevin C., Karp, Seth J., Boehm, Ulrich, Ruf-Zamojski, Frederique, Sealfon, Stuart C., Walton, Kelly L., Lee, Se-Jin and Bernard, Daniel J. (2025). Muscle-derived myostatin is a major endocrine driver of follicle-stimulating hormone synthesis. Science, 387 (6731), 329-336. doi: 10.1126/science.adi4736
2024
Journal Article
Characterization of the molecular mechanisms that govern anti‐Müllerian hormone synthesis and activity
Stocker, William A., Howard, James A., Maskey, Shreya, Luan, Haitong, Harrison, Sophie G., Hart, Kaitlin N., Hok, Lucija, Thompson, Thomas B., Walton, Kelly L. and Harrison, Craig A. (2024). Characterization of the molecular mechanisms that govern anti‐Müllerian hormone synthesis and activity. The FASEB Journal, 38 (1) e23377, 1-18. doi: 10.1096/fj.202301335rr
2023
Journal Article
Activin A level is associated with physical function in critically ill patients
Wang, Yi Tian, Harrison, Craig A., Skinner, Elizabeth H., Haines, Kimberley J., Holdsworth, Clare, Lang, Jenna K., Hibbert, Elizabeth, Scott, David, Eynon, Nir, Tiruvoipati, Ravindranath, French, Craig J., Stepto, Nigel K., Bates, Samantha, Walton, Kelly L., Crozier, Tim M. and Haines, Terry P. (2023). Activin A level is associated with physical function in critically ill patients. Australian Critical Care, 36 (5), 702-707. doi: 10.1016/j.aucc.2022.10.019
2023
Journal Article
Targeting activins and inhibins to treat reproductive disorders and cancer cachexia
Hagg, Adam, O'Shea, Eliza, Harrison, Craig A. and Walton, Kelly Louise (2023). Targeting activins and inhibins to treat reproductive disorders and cancer cachexia. Journal of Endocrinology, 258 (1) e220290, 1-15. doi: 10.1530/joe-22-0290
2023
Journal Article
Follistatin forms a stable complex with Inhibin A that does not interfere with Activin A antagonism
Kappes, Emily C, Kattamuri, Chandramohan, Czepnik, Magdalena, Yarawsky, Alexander E, Brûlé, Emilie, Wang, Ying, Ongaro, Luisina, Herr, Andrew B, Walton, Kelly L, Bernard, Daniel J and Thompson, Thomas B (2023). Follistatin forms a stable complex with Inhibin A that does not interfere with Activin A antagonism. Endocrinology, 164 (3) bqad017. doi: 10.1210/endocr/bqad017
2022
Journal Article
Inhibin inactivation in female mice leads to elevated FSH levels, ovarian over-stimulation, and pregnancy loss
Walton, Kelly L., Goney, Monica P., Peppas, Zoe, Stringer, Jessica M., Winship, Amy, Hutt, Karla, Goodchild, Georgia, Maskey, Shreya, Chan, Karen L., Brûlé, Emilie, Bernard, Daniel J., Stocker, William A. and Harrison, Craig A. (2022). Inhibin inactivation in female mice leads to elevated FSH levels, ovarian over-stimulation, and pregnancy loss. Endocrinology, 163 (4) bqac025. doi: 10.1210/endocr/bqac025
2022
Journal Article
Human INHBB gene variant (c.1079T>C:p.Met360Thr) alters testisgerm cell content, but does not impact fertility in mice
Houston, Brendan J, O’Connor, Anne E, Wang, Degang, Goodchild, Georgia, Merriner, D Jo, Luan, Haitong, Conrad, Don F, Nagirnaja, Liina, Aston, Kenneth I, Kliesch, Sabine, Wyrwoll, Margot J, Friedrich, Corinna, Tüttelmann, Frank, Harrison, Craig, O’Bryan, Moira K and Walton, Kelly (2022). Human INHBB gene variant (c.1079T>C:p.Met360Thr) alters testisgerm cell content, but does not impact fertility in mice. Endocrinology, 163 (3) bqab269. doi: 10.1210/endocr/bqab269
2021
Journal Article
TGFBR3L is an inhibin B co-receptor that regulates female fertility
Brûlé, Emilie, Wang, Ying, Li, Yining, Lin, Yeu-Farn, Zhou, Xiang, Ongaro, Luisina, Alonso, Carlos A. I., Buddle, Evan R. S., Schneyer, Alan L., Byeon, Chang-Hyeock, Hinck, Cynthia S., Mendelev, Natalia, Russell, John P., Cowan, Mitra, Boehm, Ulrich, Ruf-Zamojski, Frederique, Zamojski, Michel, Andoniadou, Cynthia L., Sealfon, Stuart C., Harrison, Craig A., Walton, Kelly L., Hinck, Andrew P. and Bernard, Daniel J. (2021). TGFBR3L is an inhibin B co-receptor that regulates female fertility. Science Advances, 7 (51) eabl4391, eabl4391. doi: 10.1126/sciadv.abl4391
2021
Journal Article
Structure of AMH bound to AMHR2 provides insight into a unique signaling pair in the TGF-β family
Hart, Kaitlin N., Stocker, William A., Nagykery, Nicholas G., Walton, Kelly L., Harrison, Craig A., Donahoe, Patricia K., Pépin, David and Thompson, Thomas B. (2021). Structure of AMH bound to AMHR2 provides insight into a unique signaling pair in the TGF-β family. Proceedings of the National Academy of Sciences of the United States of America, 118 (26) e2104809118. doi: 10.1073/pnas.2104809118
2020
Journal Article
TMEPAI/PMEPA1 is a positive regulator of skeletal muscle mass
Hagg, Adam, Kharoud, Swati, Goodchild, Georgia, Goodman, Craig A., Chen, Justin L., Thomson, Rachel E., Qian, Hongwei, Gregorevic, Paul, Harrison, Craig A. and Walton, Kelly L. (2020). TMEPAI/PMEPA1 is a positive regulator of skeletal muscle mass. Frontiers in Physiology, 11 560225, 560225. doi: 10.3389/fphys.2020.560225
2020
Journal Article
New insights into the genetic basis of premature ovarian insufficiency: novel causative variants and candidate genes revealed by genomic sequencing
Jaillard, Sylvie, Bell, Katrina, Akloul, Linda, Walton, Kelly, McElreavy, Kenneth, Stocker, William A., Beaumont, Marion, Harrisson, Craig, Jääskeläinen, Tiina, Palvimo, Jorma J., Robevska, Gorjana, Launay, Erika, Satié, Anne-Pascale, Listyasari, Nurin, Bendavid, Claude, Sreenivasan, Rajini, Duros, Solène, van den Bergen, Jocelyn, Henry, Catherine, Domin-Bernhard, Mathilde, Cornevin, Laurence, Dejucq-Rainsford, Nathalie, Belaud-Rotureau, Marc-Antoine, Odent, Sylvie, Ayers, Katie L., Ravel, Célia, Tucker, Elena J. and Sinclair, Andrew H. (2020). New insights into the genetic basis of premature ovarian insufficiency: novel causative variants and candidate genes revealed by genomic sequencing. Maturitas, 141, 9-19. doi: 10.1016/j.maturitas.2020.06.004
2020
Journal Article
Engineering the ovarian hormones inhibin A and inhibin B to enhance synthesis and activity
Goney, Monica P., Wilce, Matthew C. J., Wilce, Jacqueline A., Stocker, William A., Goodchild, Georgia M., Chan, Karen L., Harrison, Craig A. and Walton, Kelly L. (2020). Engineering the ovarian hormones inhibin A and inhibin B to enhance synthesis and activity. Endocrinology, 161 (8) bqaa099, 1-12. doi: 10.1210/endocr/bqaa099
2020
Journal Article
A variant of human growth differentiation factor-9 that improves oocyte developmental competence
Stocker, William A., Walton, Kelly L., Richani, Dulama, Chan, Karen L., Beilby, Kiri H., Finger, Bethany J., Green, Mark P., Gilchrist, Robert B. and Harrison, Craig A. (2020). A variant of human growth differentiation factor-9 that improves oocyte developmental competence. Journal of Biological Chemistry, 295 (23), 7981-7991. doi: 10.1074/jbc.ra120.013050
2019
Journal Article
Activin A–induced cachectic wasting is attenuated by systemic delivery of its cognate propeptide in male mice
Walton, Kelly L., Chen, Justin L., Arnold, Quinn, Kelly, Emily, La, Mylinh, Lu, Louis, Lovrecz, George, Hagg, Adam, Colgan, Timothy D., Qian, Hongwei, Gregorevic, Paul and Harrison, Craig A. (2019). Activin A–induced cachectic wasting is attenuated by systemic delivery of its cognate propeptide in male mice. Endocrinology, 160 (10), 2417-2426. doi: 10.1210/en.2019-00257
2019
Journal Article
Serum concentrations of oocyte-secreted factors BMP15 and GDF9 during IVF and in women with reproductive pathologies
Riepsamen, Angelique H., Chan, Karen, Lien, Shelly, Sweeten, Prudence, Donoghoe, Mark W., Walker, Glenda, Fraison, Eloïse H. J., Stocker, William A., Walton, Kelly L., Harrison, Craig A., Ledger, William L., Robertson, David M. and Gilchrist, Robert B. (2019). Serum concentrations of oocyte-secreted factors BMP15 and GDF9 during IVF and in women with reproductive pathologies. Endocrinology, 160 (10), 2298-2313. doi: 10.1210/en.2019-00264
2019
Journal Article
Functional characterization of two new variants in the bone morphogenetic protein 7 prodomain in two pairs of monozygotic twins with hypospadias
Bouty, Aurore, Walton, Kelly, Listyasari, Nurin Aisyiyah, Robevska, Gorjana, Van den Bergen, Jocelyn, Santosa, Ardy, Faradz, Sultana M H, Harrison, Craig, Ayers, Katie L and Sinclair, Andrew H (2019). Functional characterization of two new variants in the bone morphogenetic protein 7 prodomain in two pairs of monozygotic twins with hypospadias. Journal of the Endocrine Society, 3 (4), 814-824. doi: 10.1210/js.2018-00333
2019
Journal Article
Cumulin and FSH Cooperate to Regulate Inhibin B and Activin B Production by Human Granulosa-Lutein Cells In Vitro
Richani, Dulama, Constance, Katherine, Lien, Shelly, Agapiou, David, Stocker, William A., Hedger, Mark P., Ledger, William L., Thompson, Jeremy G., Robertson, David M., Mottershead, David G., Walton, Kelly L., Harrison, Craig A. and Gilchrist, Robert B. (2019). Cumulin and FSH Cooperate to Regulate Inhibin B and Activin B Production by Human Granulosa-Lutein Cells In Vitro. Endocrinology, 160 (4), 853-862. doi: 10.1210/en.2018-01026
2018
Journal Article
Inhibin: To Betaglycan, or Not to Betaglycan
Walton, Kelly L. and Harrison, Craig A. (2018). Inhibin: To Betaglycan, or Not to Betaglycan. Endocrinology, 160 (2), 341-342. doi: 10.1210/en.2018-01049
2018
Journal Article
Molecular characterization of latent GDF8 reveals mechanisms of activation
Walker, Ryan G., McCoy, Jason C., Czepnik, Magdalena, Mills, Melanie J., Hagg, Adam, Walton, Kelly L., Cotton, Thomas R., Hyvönen, Marko, Lee, Richard T., Gregorevic, Paul, Harrison, Craig A. and Thompson, Thomas B. (2018). Molecular characterization of latent GDF8 reveals mechanisms of activation. Proceedings of the National Academy of Sciences of the United States of America, 115 (5), E866-E875. doi: 10.1073/pnas.1714622115
Funding
Current funding
Supervision
Availability
- Dr Kelly Walton is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Transforming growth factors to alter metabolic and functional physiology in health and disease.
Principal Advisor
Other advisors: Associate Professor Frederik Steyn, Dr Adam Hagg
Media
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