Overview
Availability
- Dr Kelly Walton is:
- Available for supervision
Works
Search Professor Kelly Walton’s works on UQ eSpace
2017
Journal Article
Targeting TGF-β mediated SMAD signaling for the prevention of fibrosis
Walton, Kelly L., Johnson, Katharine E. and Harrison, Craig A. (2017). Targeting TGF-β mediated SMAD signaling for the prevention of fibrosis. Frontiers in Pharmacology, 8 (JUL) 461. doi: 10.3389/fphar.2017.00461
2017
Journal Article
Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease
Chen, Justin L., Walton, Kelly L., Hagg, Adam, Colgan, Timothy D., Johnson, Katharine, Qian, Hongwei, Gregorevic, Paul and Harrison, Craig A. (2017). Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease. Proceedings of the National Academy of Sciences of the United States of America, 114 (26), E5266-E5275. doi: 10.1073/pnas.1620013114
2017
Journal Article
Multiple Soluble TGF-β Receptors in Addition to Soluble Endoglin Are Elevated in Preeclamptic Serum and They Synergistically Inhibit TGF-β Signaling
Wang, Yao, Chen, Qi, Zhao, Min, Walton, Kelly, Harrison, Craig and Nie, Guiying (2017). Multiple Soluble TGF-β Receptors in Addition to Soluble Endoglin Are Elevated in Preeclamptic Serum and They Synergistically Inhibit TGF-β Signaling. The Journal of Clinical Endocrinology & Metabolism, 102 (8), 3065-3074. doi: 10.1210/jc.2017-01150
2017
Journal Article
Structural basis for potency differences between GDF8 and GDF11
Walker, Ryan G., Czepnik, Magdalena, Goebel, Erich J., McCoy, Jason C., Vujic, Ana, Cho, Miook, Oh, Juhyun, Aykul, Senem, Walton, Kelly L., Schang, Gauthier, Bernard, Daniel J., Hinck, Andrew P., Harrison, Craig A., Martinez-Hackert, Erik, Wagers, Amy J., Lee, Richard T. and Thompson, Thomas B. (2017). Structural basis for potency differences between GDF8 and GDF11. BMC Biology, 15 (1) 19. doi: 10.1186/s12915-017-0350-1
2017
Journal Article
BMP15 mutations associated with primary ovarian insufficiency reduce expression, activity, or synergy with GDF9
Patino, Liliana C., Walton, Kelly L., Mueller, Thomas D., Johnson, Katharine E., Stocker, William, Richani, Dulama, Agapiou, David, Gilchrist, Robert B., Laissue, Paul and Harrison, Craig A. (2017). BMP15 mutations associated with primary ovarian insufficiency reduce expression, activity, or synergy with GDF9. Journal of Clinical Endocrinology and Metabolism, 102 (3), 1009-1019. doi: 10.1210/jc.2016-3503
2017
Journal Article
The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma
Coulson, Rhiannon, Liew, Seng H., Connelly, Angela A., Yee, Nicholas S., Deb, Siddhartha, Kumar, Beena, Vargas, Ana C., O'Toole, Sandra A., Parslow, Adam C., Poh, Ashleigh, Putoczki, Tracy, Morrow, Riley J., Alorro, Mariah, Lazarus, Kyren A., Yeap, Evie F.W., Walton, Kelly L., Harrison, Craig A., Hannan, Natalie J., George, Amee J., Clyne, Colin D., Ernst, Matthias, Allen, Andrew M. and Chand, Ashwini L. (2017). The angiotensin receptor blocker, Losartan, inhibits mammary tumor development and progression to invasive carcinoma. Oncotarget, 8 (12), 18640-18656. doi: 10.18632/oncotarget.15553
2016
Journal Article
Differential effects of IL6 and activin A in the development of cancer-associated cachexia
Chen, Justin L., Walton, Kelly L., Qian, Hongwei, Colgan, Timothy D., Hagg, Adam, Watt, Matthew J., Harrison, Craig A. and Gregorevic, Paul (2016). Differential effects of IL6 and activin A in the development of cancer-associated cachexia. Cancer Research, 76 (18), 5372-5382. doi: 10.1158/0008-5472.CAN-15-3152
2016
Journal Article
Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice
Winbanks, Catherine E., Murphy, Kate T., Bernardo, Bianca C., Qian, Hongwei, Liu, Yingying, Sepulveda, Patricio V., Beyer, Claudia, Hagg, Adam, Thomson, Rachel E., Chen, Justin L., Walton, Kelly L., Loveland, Kate L., McMullen, Julie R., Rodgers, Buel D., Harrison, Craig A., Lynch, Gordon S. and Gregorevic, Paul (2016). Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice. Science Translational Medicine, 8 (348) 348ra98. doi: 10.1126/scitranslmed.aac4976
2016
Journal Article
A novel, more efficient approach to generate bioactive inhibins
Walton, Kelly L., Kelly, Emily K., Johnson, Katharine E., Robertson, David M., Stanton, Peter G. and Harrison, Craig A. (2016). A novel, more efficient approach to generate bioactive inhibins. Endocrinology, 157 (7), 2799-2809. doi: 10.1210/en.2015-1963
2016
Book Chapter
The TGF-β signalling network in muscle development, adaptation and disease
Chen, Justin L., Colgan, Timothy D., Walton, Kelly L., Gregorevic, Paul and Harrison, Craig A. (2016). The TGF-β signalling network in muscle development, adaptation and disease. Advances in Experimental Medicine and Biology. (pp. 97-131) Springer New York LLC. doi: 10.1007/978-3-319-27511-6_5
2016
Journal Article
Biological activity and <i>in vivo</i> half-life of pro-activin A in male rats
Johnson, Katharine E., Makanji, Yogeshwar, Temple-Smith, Peter, Kelly, Emily K., Barton, Peter A., Al-Musawi, Sara L., Mueller, Thomas D., Walton, Kelly L. and Harrison, Craig A. (2016). Biological activity and in vivo half-life of pro-activin A in male rats. Molecular and Cellular Endocrinology, 422 (C), 84-92. doi: 10.1016/j.mce.2015.12.007
2015
Journal Article
Inhibin Biosynthesis and Activity Are Limited by a Prodomain-Derived Peptide
Walton, Kelly L., Kelly, Emily K., Chan, Karen L., Harrison, Craig A. and Robertson, David M. (2015). Inhibin Biosynthesis and Activity Are Limited by a Prodomain-Derived Peptide. Endocrinology, 156 (8), 3047-3057. doi: 10.1210/en.2014-2005
2015
Journal Article
Development of a high-throughput assay for human proprotein convertase 5/6 for detecting uterine receptivity
Heng, Sophea, Dynon, Kemperly, Li, Ying, Edgell, Tracey, Walton, Kelly, Rombauts, Luk J., Vollenhoven, Beverley and Nie, Guiying (2015). Development of a high-throughput assay for human proprotein convertase 5/6 for detecting uterine receptivity. Analytical Biochemistry, 475, 14-21. doi: 10.1016/j.ab.2014.12.012
2015
Journal Article
Development of novel activin-targeted therapeutics
Chen, Justin L., Walton, Kelly L., Al-Musawi, Sara L., Kelly, Emily K., Qian, Hongwei, La, Mylinh, Lu, Louis, Lovrecz, George, Ziemann, Mark, Lazarus, Ross, El-Osta, Assam, Gregorevic, Paul and Harrison, Craig A. (2015). Development of novel activin-targeted therapeutics. Molecular Therapy, 23 (3), 434-444. doi: 10.1038/mt.2014.221
2014
Journal Article
Elevated expression of activins promotes muscle wasting and cachexia
Chen, Justin L., Walton, Kelly L., Winbanks, Catherine E., Murphy, Kate T., Thomson, Rachel E., Makanji, Yogeshwar, Qian, Hongwei, Lynch, Gordon S., Harrison, Craig A. and Gregorevic, Paul (2014). Elevated expression of activins promotes muscle wasting and cachexia. Faseb Journal, 28 (4), 1711-1723. doi: 10.1096/fj.13-245894
2014
Journal Article
Germline mutations of inhibins in early-onset ovarian epithelial tumors
Tournier, Isabelle, Marlin, Régine, Walton, Kelly, Charbonnier, Françoise, Coutant, Sophie, Théry, Jean-Christophe, Charbonnier, Camille, Spurrell, Cailyn, Vezain, Myriam, Ippolito, Lorena, Bougeard, Gaëlle, Roman, Horace, Tinat, Julie, Sabourin, Jean-Christophe, Stoppa-Lyonnet, Dominique, Caron, Olivier, Bressac-de Paillerets, Brigitte, Vaur, Dominique, King, Mary-Claire, Harrison, Craig and Frebourg, Thierry (2014). Germline mutations of inhibins in early-onset ovarian epithelial tumors. Human Mutation, 35 (3), 294-297. doi: 10.1002/humu.22489
2013
Journal Article
Identification of protein binding partners of ALK-5 kinase inhibitors
Ciayadi, Rudy, Kelso, Geoffrey F., Potdar, Mahesh K., Harris, Simon J., Walton, Kelly L., Harrison, Craig A. and Hearn, Milton T. W. (2013). Identification of protein binding partners of ALK-5 kinase inhibitors. Bioorganic & Medicinal Chemistry, 21 (21), 6496-6500. doi: 10.1016/j.bmc.2013.08.038
2013
Journal Article
Species Differences in the Expression and Activity of Bone Morphogenetic Protein 15
Al-Musawi, Sara L., Walton, Kelly L., Heath, Derek, Simpson, Courtney M. and Harrison, Craig A. (2013). Species Differences in the Expression and Activity of Bone Morphogenetic Protein 15. Endocrinology, 154 (2), 888-899. doi: 10.1210/en.2012-2015
2012
Journal Article
Activin signaling regulates sertoli cell differentiation and function
Nicholls, Peter K., Stanton, Peter G., Chen, Justin L., Olcorn, Justine S., Haverfield, Jenna T., Qian, Hongwei, Walton, Kelly L., Gregorevic, Paul and Harrison, Craig A. (2012). Activin signaling regulates sertoli cell differentiation and function. Endocrinology, 153 (12), 6065-6077. doi: 10.1210/en.2012-1821
2012
Journal Article
HtrA3 as an Early Marker for Preeclampsia: Specific Monoclonal Antibodies and Sensitive High-Throughput Assays for Serum Screening
Dynon, Kemperly, Heng, Sophea, Puryer, Michelle, Li, Ying, Walton, Kelly, Endo, Yaeta and Nie, Guiying (2012). HtrA3 as an Early Marker for Preeclampsia: Specific Monoclonal Antibodies and Sensitive High-Throughput Assays for Serum Screening. Plos One, 7 (9) e45956. doi: 10.1371/journal.pone.0045956
Funding
Current funding
Supervision
Availability
- Dr Kelly Walton is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Transforming growth factors to alter metabolic and functional physiology in health and disease.
Principal Advisor
Other advisors: Associate Professor Frederik Steyn, Dr Adam Hagg
Media
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