Dr M. Zeeshan Chaudhry
Dr

M. Zeeshan Chaudhry

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Background

Zeeshan Chaudhry is an emerging expert in virus immunology. His research focuses on the transcriptional regulation of immune cells, particularly CD8⁺ T cells and innate lymphoid cells, including NK cells and ILCs. He aims to uncover the molecular mechanisms that guide the development of long-lived memory T cells, which are critical for durable protective immunity. A key interest of his work is how stem-like progenitors of these cells can be manipulated to combat chronic diseases.

Dr. Chaudhry received his doctoral training at the Helmholtz Centre for Infection Research in Germany, where he investigated viral immune evasion strategies. His research has been published in leading journals such as Nature Immunology, Immunity, PNAS, and PLOS Pathogens.

Availability

Dr M. Zeeshan Chaudhry is:
Available for supervision

Search Professor M. Zeeshan Chaudhry’s works on UQ eSpace

17 works between 2016 and 2025
All (17) Journal Article (16) Book Chapter (1)

1 - 17 of 17 works

Featured

2024

Journal Article

NFAT signaling is indispensable for persistent memory responses of MCMV-specific CD8+ T cells

Chaudhry, M. Zeeshan, Borkner, Lisa, Kulkarni, Upasana, Berberich-Siebelt, Friederike and Cicin-Sain, Luka (2024). NFAT signaling is indispensable for persistent memory responses of MCMV-specific CD8+ T cells. PLoS Pathogens, 20 (2 February) e1012025. doi: 10.1371/journal.ppat.1012025

NFAT signaling is indispensable for persistent memory responses of MCMV-specific CD8+ T cells

Featured

2022

Journal Article

Rapid SARS-CoV-2 adaptation to available cellular proteases

Chaudhry, M. Zeeshan, Eschke, Kathrin, Hoffmann, Markus, Grashoff, Martina, Abassi, Leila, Kim, Yeonsu, Brunotte, Linda, Ludwig, Stephan, Kröger, Andrea, Klawonn, Frank, Pöhlmann, Stefan H. and Cicin-Sain, Luka (2022). Rapid SARS-CoV-2 adaptation to available cellular proteases. Journal of Virology, 96 (5) e0218621, 1-17. doi: 10.1128/jvi.02186-21

Rapid SARS-CoV-2 adaptation to available cellular proteases

Featured

2020

Journal Article

Cytomegalovirus inhibition of extrinsic apoptosis determines fitness and resistance to cytotoxic CD8 T cells

Zeeshan Chaudhry, M., Casalegno-Garduno, Rosaely, Sitnik, Katarzyna M., Kasmapour, Bahram, Pulm, Ann-Kathrin, Brizic, Ilija, Eiz-Vesper, Britta, Moosmann, Andreas, Jonjic, Stipan, Mocarski, Edward S. and Cicin-Sain, Luka (2020). Cytomegalovirus inhibition of extrinsic apoptosis determines fitness and resistance to cytotoxic CD8 T cells. Proceedings of the National Academy of Sciences of the United States of America, 117 (23), 12961-12968. doi: 10.1073/pnas.1914667117

Cytomegalovirus inhibition of extrinsic apoptosis determines fitness and resistance to cytotoxic CD8 T cells

2025

Journal Article

Distinctive CD8+ T cell activation by antigen-presenting plasmacytoid dendritic cells compared to conventional dendritic cells

van der Sluis, Renée M., García-Rodríguez, Juan L., Nielsen, Ian Helstrup, Gris-Oliver, Albert, Becker, Jennifer, Costa, Bibiana, Chaudhry, M. Zeeshan, Werner, Marvin, Laustsen, Anders, Pedersen, Jesper G., Gammelgaard, Kristine R., Mogensen, Trine H., Kalinke, Ulrich, Cicin-Sain, Luka, Bak, Rasmus O., Kristensen, Lasse S. and Jakobsen, Martin R. (2025). Distinctive CD8+ T cell activation by antigen-presenting plasmacytoid dendritic cells compared to conventional dendritic cells. Cell Reports, 44 (3) 115413, 115413-3. doi: 10.1016/j.celrep.2025.115413

Distinctive CD8+ T cell activation by antigen-presenting plasmacytoid dendritic cells compared to conventional dendritic cells

2024

Journal Article

Chameleon impersonation of NK cells and ILC1s

Chaudhry, M. Zeeshan and Belz, Gabrielle T. (2024). Chameleon impersonation of NK cells and ILC1s. Nature Immunology, 25 (8), 1313-1315. doi: 10.1038/s41590-024-01886-x

Chameleon impersonation of NK cells and ILC1s

2024

Journal Article

A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants

Metzdorf, Kristin, Jacobsen, Henning, Kim, Yeonsu, Teixeira Alves, Luiz Gustavo, Kulkarni, Upasana, Brdovčak, Maja Cokarić, Materljan, Jelena, Eschke, Kathrin, Chaudhry, M. Zeeshan, Hoffmann, Markus, Bertoglio, Federico, Ruschig, Maximilian, Hust, Michael, Šustić, Marko, Krmpotić, Astrid, Jonjić, Stipan, Widera, Marek, Ciesek, Sandra, Pöhlmann, Stefan, Landthaler, Markus and Čičin-Šain, Luka (2024). A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants. Frontiers in Immunology, 15 1383086, 1-18. doi: 10.3389/fimmu.2024.1383086

A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants

2024

Journal Article

GFI1B specifies developmental potential of innate lymphoid cell progenitors in the lungs

Huang, Qiutong, Cao, Wang H.J., Curio, Sophie, Yu, Huiyang, Denman, Renae, Chen, Evelyn, Schreuder, Jaring, Dight, James, Chaudhry, M., Jacquelot, Nicolas, Wimmer, Verena C., Seillet, Cyril, Möröy, Tarik and Belz, Gabrielle T. (2024). GFI1B specifies developmental potential of innate lymphoid cell progenitors in the lungs. Science Immunology, 9 (95) eadj2654, eadj2654. doi: 10.1126/sciimmunol.adj2654

GFI1B specifies developmental potential of innate lymphoid cell progenitors in the lungs

2024

Journal Article

Decidual-tissue-resident memory T cells protect against nonprimary human cytomegalovirus infection at the maternal-fetal interface

Alfi, Or, Cohen, Mevaseret, Bar-On, Shikma, Hashimshony, Tamar, Levitt, Lorinne, Raz, Yael, Blecher, Yair, Chaudhry, M. Zeeshan, Cicin-Sain, Luka, Ben-El, Rina, Oiknine-Djian, Esther, Lahav, Tamar, Vorontsov, Olesya, Cohen, Adiel, Zakay-Rones, Zichria, Daniel, Leonor, Berger, Michael, Mandel-Gutfreund, Yael, Panet, Amos and Wolf, Dana G. (2024). Decidual-tissue-resident memory T cells protect against nonprimary human cytomegalovirus infection at the maternal-fetal interface. Cell Reports, 43 (2) 113698. doi: 10.1016/j.celrep.2024.113698

Decidual-tissue-resident memory T cells protect against nonprimary human cytomegalovirus infection at the maternal-fetal interface

2022

Journal Article

ORFeome phage display reveals a major immunogenic epitope on the S2 subdomain of SARS-CoV-2 spike protein

Ballmann, Rico, Hotop, Sven-Kevin, Bertoglio, Federico, Steinke, Stephan, Heine, Philip Alexander, Chaudhry, M. Zeeshan, Jahn, Dieter, Pucker, Boas, Baldanti, Fausto, Piralla, Antonio, Schubert, Maren, Čičin-Šain, Luka, Brönstrup, Mark, Hust, Michael and Dübel, Stefan (2022). ORFeome phage display reveals a major immunogenic epitope on the S2 subdomain of SARS-CoV-2 spike protein. Viruses, 14 (6) 1326, 1-13. doi: 10.3390/v14061326

ORFeome phage display reveals a major immunogenic epitope on the S2 subdomain of SARS-CoV-2 spike protein

2022

Journal Article

MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination

Kim, Yeonsu, Zheng, Xiaoyan, Eschke, Kathrin, Chaudhry, M. Zeeshan, Bertoglio, Federico, Tomić, Adriana, Krmpotić, Astrid, Hoffmann, Markus, Bar-On, Yotam, Boehme, Julia, Bruder, Dunja, Ebensen, Thomas, Brunotte, Linda, Ludwig, Stephan, Messerle, Martin, Guzman, Carlos, Mandelboim, Ofer, Hust, Michael, Pöhlmann, Stefan, Jonjić, Stipan and Čičin-Šain, Luka (2022). MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination. Cellular and Molecular Immunology, 19 (2), 234-244. doi: 10.1038/s41423-021-00814-5

MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination

2021

Journal Article

Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection

Flommersfeld, Sophie, Böttcher, Jan P., Ersching, Jonatan, Flossdorf, Michael, Meiser, Philippa, Pachmayr, Ludwig O., Leube, Justin, Hensel, Inge, Jarosch, Sebastian, Zhang, Qin, Chaudhry, M. Zeeshan, Andrae, Immanuel, Schiemann, Matthias, Busch, Dirk.H., Cicin-Sain, Luka, Sun, Joseph C., Gasteiger, Georg, Victora, Gabriel D., Höfer, Thomas, Buchholz, Veit R. and Grassmann, Simon (2021). Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection. Immunity, 54 (10), 2288-2304.e7. doi: 10.1016/j.immuni.2021.08.002

Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection

2021

Journal Article

Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy

Müller, Thomas R., Jarosch, Sebastian, Hammel, Monika, Leube, Justin, Grassmann, Simon, Bernard, Bettina, Effenberger, Manuel, Andrä, Immanuel, Chaudhry, M. Zeeshan, Käuferle, Theresa, Malo, Antje, Cicin-Sain, Luka, Steinberger, Peter, Feuchtinger, Tobias, Protzer, Ulrike, Schumann, Kathrin, Neuenhahn, Michael, Schober, Kilian and Busch, Dirk H. (2021). Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy. Cell Reports Medicine, 2 (8) 100374, 100374. doi: 10.1016/j.xcrm.2021.100374

Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy

2021

Journal Article

A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations

Bertoglio, Federico, Fühner, Viola, Ruschig, Maximilian, Heine, Philip Alexander, Abassi, Leila, Klünemann, Thomas, Rand, Ulfert, Meier, Doris, Langreder, Nora, Steinke, Stephan, Ballmann, Rico, Schneider, Kai-Thomas, Roth, Kristian Daniel Ralph, Kuhn, Philipp, Riese, Peggy, Schäckermann, Dorina, Korn, Janin, Koch, Allan, Chaudhry, M Zeeshan, Eschke, Kathrin, Kim, Yeonsu, Zock-Emmenthal, Susanne, Becker, Marlies, Scholz, Margitta, Moreira, Gustavo Marçal Schmidt Garcia, Wenzel, Esther Veronika, Russo, Giulio, Garritsen, Hendrikus S P, Casu, Sebastian ... Hust, Michael (2021). A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations. Cell Reports, 36 (4) 109433, 1-23. doi: 10.1016/j.celrep.2021.109433

A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients binds to the ACE2-RBD interface and is tolerant to most known RBD mutations

2021

Book Chapter

Construction of human cytomegalovirus mutants with markerless BAC mutagenesis

Chaudhry, M. Zeeshan, Messerle, Martin and Čičin-Šain, Luka (2021). Construction of human cytomegalovirus mutants with markerless BAC mutagenesis. Human cytomegaloviruses: methods and protocols. (pp. 133-158) edited by Andrew D. Yurochko. New York, NY, United States: Springer/Humana Press. doi: 10.1007/978-1-0716-1111-1_8

Construction of human cytomegalovirus mutants with markerless BAC mutagenesis

2020

Journal Article

Early emergence of T central memory precursors programs clonal dominance during chronic viral infection

Grassmann, Simon, Mihatsch, Lorenz, Mir, Jonas, Kazeroonian, Atefeh, Rahimi, Roza, Flommersfeld, Sophie, Schober, Kilian, Hensel, Inge, Leube, Justin, Pachmayr, Ludwig O., Kretschmer, Lorenz, Zhang, Qin, Jolly, Adrien, Chaudhry, M. Zeeshan, Schiemann, Matthias, Cicin-Sain, Luka, Höfer, Thomas, Busch, Dirk H., Flossdorf, Michael and Buchholz, Veit R. (2020). Early emergence of T central memory precursors programs clonal dominance during chronic viral infection. Nature Immunology, 21 (12), 1563-1573. doi: 10.1038/s41590-020-00807-y

Early emergence of T central memory precursors programs clonal dominance during chronic viral infection

2017

Journal Article

UL36 rescues apoptosis inhibition and in vivo replication of a chimeric MCMV lacking the M36 gene

Chaudhry, M. Zeeshan, Kasmapour, Bahram, Plaza-Sirvent, Carlos, Bajagic, Milica, Garduño, Rosaely Casalegno, Borkner, Lisa, Roviš, Tihana Lenac, Scrima, Andrea, Jonjic, Stipan, Schmitz, Ingo and Cicin-Sain, Luka (2017). UL36 rescues apoptosis inhibition and in vivo replication of a chimeric MCMV lacking the M36 gene. Frontiers in Cellular and Infection Microbiology, 7 (JUL) 312, 1-12. doi: 10.3389/fcimb.2017.00312

UL36 rescues apoptosis inhibition and in vivo replication of a chimeric MCMV lacking the M36 gene

2016

Journal Article

Colonization of plant growth promoting rhizobacteria (PGPR) on two different root systems

Chaudhry, Muhammad Zeeshan, Naz, Asad Ullah, Nawaz, Ahmed, Nawaz, Ali, Mukhtar, Hamid and Irfan-Ul-Haq, Muhammad (2016). Colonization of plant growth promoting rhizobacteria (PGPR) on two different root systems. Pakistan Journal of Botany, 48 (4), 1691-1696.

Colonization of plant growth promoting rhizobacteria (PGPR) on two different root systems

Availability

Dr M. Zeeshan Chaudhry is:
Available for supervision

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Supervision history

Current supervision

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