Overview
Background
Dr Mari Takashima is a nurse-statistician and clinical trialist whose research centres on medical device safety in paediatric and neonatal populations. She is a certified health informatician with expertise in clinical epidemiology, clinical trials, applied biostatistics, and health informatics.
Her research program focuses on the utilisation and safety of invasive medical devices, including vascular access devices, cardiopulmonary bypass circuits, and extracorporeal membrane oxygenation. Her current research interests include the safety of plastic chemicals in medical devices. This emerging program investigates chemical leaching of plasticisers such as DEHP and BPA from plastic circuits and tubing used in paediatric and neonatal care, and the potential health consequences of cumulative exposure in vulnerable patients.
Availability
- Dr Mari Takashima is:
- Available for supervision
Qualifications
- Bachelor of Nursing, Griffith University
- Graduate Certificate in Critical Care Nursing, Queensland University of Technology
- Masters (Research) of Clinical Epidemiology, The University of Queensland
- Doctor of Philosophy of Epidemiology and Biostatistics, Griffith University
Research interests
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Paediatric medical device safety
I investigate how to make medical devices safer for children, from vascular access devices such as cannulas and central lines to feeding devices and life support circuits. My work examines device complications including blockage, blood clots, infection, skin injury and device failure in newborn, paediatric and intensive care settings. I am an investigator on three national trials testing safer device selection and care.
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Plastic chemical exposure from medical devices
I study how chemicals such as phthalates and bisphenol A leach from plastic medical devices into vulnerable patients. My focus is newborns and children exposed during cardiac surgery on bypass, extracorporeal life support, dialysis and intravenous therapy. This work combines laboratory testing, clinical studies and evidence reviews to identify safer devices and inform hospital purchasing and clinical practice.
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Evidence synthesis and meta-analysis
I conduct systematic reviews, scoping reviews and network meta-analyses. My work includes reviews of antimicrobial catheter impregnation, central venous access device securement and chemical leaching from devices, providing evidence to guide clinical decisions and practice guidelines.
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Biostatistics and health research methods
I lead statistical design and analysis across a wide range of health research, including clinical trials, cohort studies, data linkage studies, surveys and quality improvement projects. My expertise spans trial design, causal inference, longitudinal and survival analysis, and analysis of routinely collected hospital data. I am passionate about matching the right statistical method to the right research question.
Works
Search Professor Mari Takashima’s works on UQ eSpace
2025
Journal Article
Comparable achievement of workplace performance of student and graduate nurses: A quantitative cohort evaluation
Spiller, Katharina, Ossenberg, Christine, Takashima, Mari and Henderson, Amanda (2025). Comparable achievement of workplace performance of student and graduate nurses: A quantitative cohort evaluation. Nurse Education in Practice, 82 104205, 1-9. doi: 10.1016/j.nepr.2024.104205
2025
Journal Article
Barriers and enablers of dietary reintroduction following negative oral food challenge: a scoping review
Gibson, Victoria, Ullman, Amanda, Takashima, Mari and Koplin, Jennifer (2025). Barriers and enablers of dietary reintroduction following negative oral food challenge: a scoping review. The Journal of Allergy and Clinical Immunology: In Practice, 13 (4), 851-860.e7. doi: 10.1016/j.jaip.2025.01.012
2025
Journal Article
Towards equitable reporting of Indigenous status, ethnicity, language and country of birth in Australian paediatric clinical studies: a scoping review
Cunninghame, Jacqueline, Holland, Lorelle, Takashima, Mari, Nguyen, Linda, Diaz, Abbey, Guo, Shuaijun, Dufficy, Mitchell, Munns, Craig F. and Ullman, Amanda (2025). Towards equitable reporting of Indigenous status, ethnicity, language and country of birth in Australian paediatric clinical studies: a scoping review. Journal of Paediatrics and Child Health, 61 (1), 12-19. doi: 10.1111/jpc.16708
2025
Journal Article
Effectiveness of tissue adhesive for vascular access devices in paediatrics: Systematic review and meta-analysis protocol = L’efficacité des adhésifs tissulaires pour les dispositifs d’accès vasculaire en pédiatrie: Protocole d’examen systématique et de méta-analyse
de Souza, Sabrina, Takashima, Mari, Kleidon, Tricia M., Comber, Elouise, Marsh, Nicole, August, Deanne, Ullman, Amanda and Kuerten Rocha, Patricia (2025). Effectiveness of tissue adhesive for vascular access devices in paediatrics: Systematic review and meta-analysis protocol = L’efficacité des adhésifs tissulaires pour les dispositifs d’accès vasculaire en pédiatrie: Protocole d’examen systématique et de méta-analyse. Vascular Access – Journal of the Canadian Vascular Access Association, 19 (1), 47-59. doi: 10.5737/va.v19.i1.47
2025
Journal Article
Central venous access device selection and insertion in children with blood disorders and cancer: an international cross‐sectional survey
Takashima, Mari D., Hyun, Areum, de Souza, Sabrina, Gibson, Victoria, Silva, Thiago Lopes, Rocha, Patricia Kuerten, Vetcho, Siriporn, Nunn, Jenna and Ullman, Amanda J. (2025). Central venous access device selection and insertion in children with blood disorders and cancer: an international cross‐sectional survey. European Journal of Cancer Care, 2025 (1) 6671160, 1-12. doi: 10.1155/ecc/6671160
2025
Journal Article
Ending rheumatic heart disease in Aboriginal and Torres Strait Islander communities: A systematic review of prevention programs in Australia
Cai, Yumeng, Delaney, Lori J., Lynch, Debby, Cunninghame, Jacqueline, Takashima, Mari, Ullman, Amanda, Toombs, Maree, Martin, Antonella, Thompson, Kate, Maxwell, Karina, Moore, Jane, Kilgour, Catherine and Holland, Lorelle (2025). Ending rheumatic heart disease in Aboriginal and Torres Strait Islander communities: A systematic review of prevention programs in Australia. First Nations Health and Wellbeing - The Lowitja Journal, 3 100040, 1-24. doi: 10.1016/j.fnhli.2024.100040
2025
Journal Article
Reporting Indigenous status, ethnicity, language and country of birth to build equity in international paediatric clinical trials with Australian sites: a scoping review
Cunninghame, Jacqueline, Takashima, Mari, Holland, Lorelle, Nguyen, Linda, Diaz, Abbey, Guo, Shuaijun, Dufficy, Mitchell, Munns, Craig F. and Ullman, Amanda (2025). Reporting Indigenous status, ethnicity, language and country of birth to build equity in international paediatric clinical trials with Australian sites: a scoping review. Australian Health Review, 49 (1) AH24184, 1-8. doi: 10.1071/ah24184
2025
Journal Article
Wearable biosensors for pediatric hospitals: a scoping review
Hyun, Areum, Takashima, Mari, Hall, Stephanie, Lee, Leonard, Dufficy, Mitchell, Ruppel, Halley and Ullman, Amanda (2025). Wearable biosensors for pediatric hospitals: a scoping review. Pediatric Research, 98 (1), 90-99. doi: 10.1038/s41390-024-03693-4
2024
Journal Article
Extravasation identification and management in neonates and pediatrics: a cross sectional survey
Nguyen, Linda N., Takashima, Mari, Cunninghame, Jacqueline, August, Deanne and Ullman, Amanda (2024). Extravasation identification and management in neonates and pediatrics: a cross sectional survey. Hospital Pediatrics, 14 (12), 1026-1034. doi: 10.1542/hpeds.2023-007698
2024
Conference Publication
Infection prevention practices for non-tunnelled haemodialysis catheters in the intensive care unit: preliminary results from an Australia-wide cross-sectional survey
Corley, Amanda, Bloomer, Melissa, Takashima, Mari, Ullman, Amanda, Keogh, Samantha, Coyer, Fiona and Marsh, Nicole (2024). Infection prevention practices for non-tunnelled haemodialysis catheters in the intensive care unit: preliminary results from an Australia-wide cross-sectional survey. 2024 ACIPC International Conference, Melbourne, VIC Australia, 17-20 November 2024. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.idh.2024.09.029
2024
Journal Article
Use of tissue adhesive for neonatal intravenous access devices: a scoping review
de Souza, Sabrina, Takashima, Mari, Silva, Thiago Lopes, Nugyen, Linda, Kleidon, Tricia M., Jardine, Luke, Dargaville, Tim R., Ullman, Amanda, August, Deanne and Rocha, Patricia Kuerten (2024). Use of tissue adhesive for neonatal intravenous access devices: a scoping review. European Journal of Pediatrics, 183 (12), 5103-5112. doi: 10.1007/s00431-024-05800-3
2024
Journal Article
Invasive device‐associated skin complications and mechanical dysfunctions in paediatric healthcare: A systematic review and meta‐analysis
Takashima, Mari, Hyun, Areum, Gibson, Victoria, Borello, Eloise and Ullman, Amanda (2024). Invasive device‐associated skin complications and mechanical dysfunctions in paediatric healthcare: A systematic review and meta‐analysis. Journal of Advanced Nursing, 80 (10), 4034-4049. doi: 10.1111/jan.16073
2024
Journal Article
Central venous access device adverse events in pediatric patients with cancer: a systematic review and meta-analysis
Nunn, Jenna L., Takashima, Mari D., Wray-Jones, Erin M., Soosay Raj, Trisha A., Hanna, Diane M. T. and Ullman, Amanda J. (2024). Central venous access device adverse events in pediatric patients with cancer: a systematic review and meta-analysis. Supportive Care in Cancer, 32 (10) 662, 1-15. doi: 10.1007/s00520-024-08853-0
2024
Journal Article
PiccPed® app impact on nurses' knowledge to prevent adverse events for peripherally inserted central catheters (PICC) in pediatric and neonatal healthcare: A quasi-experimental study
de Souza, Sabrina, Takashima, Mari, August, Deanne, Biazus-Dalcin, Camila, Silva, Thiago Lopes, Bitencourt, Aline de Souza, Ullman, Amanda and Rocha, Patricia Kuerten (2024). PiccPed® app impact on nurses' knowledge to prevent adverse events for peripherally inserted central catheters (PICC) in pediatric and neonatal healthcare: A quasi-experimental study. Journal of Pediatric Nursing, 78, 112-117. doi: 10.1016/j.pedn.2024.06.017
2024
Conference Publication
Ending rheumatic heart disease in Aboriginal and Torres Strait Islander communities: A systematic review of prevention programs in Australia
Cai, Yumeng (Emma), Delaney, Lori, Lynch, Debby, Kilgour, Catherine, Cunninghame, Jacqueline, Toombs, Maree, Ullman, Amanda, Takashima, Mari, Maxwell, Karina, Thompson, Kate, Moore, Jane and Holland, Lorelle (2024). Ending rheumatic heart disease in Aboriginal and Torres Strait Islander communities: A systematic review of prevention programs in Australia. The National Nursing Forum, Cairns, QLD Australia, 14-16 August 2024. Canberra: Australian College of Nursing.
2024
Journal Article
Preventing adverse events during paediatric cancer treatment: protocol for a multi-site hybrid randomised controlled trial of catheter lock solutions (the CLOCK trial)
Ullman, Amanda, Takashima, Mari, Gibson, Victoria, Comber, Elouise, Borello, Eloise, Bradford, Natalie, Byrnes, Joshua, Cole, Roni, Eisenstat, David, Henson, Nicole, Howard, Philippa, Irwin, Adam, Keogh, Samantha, Kleidon, Tricia, Martin, Michelle, McCleary, Karen, McLean, Jordana, Moloney, Susan, Monagle, Paul, Moore, Andrew, Newall, Fiona, Noyes, Michelle, Rowan, Gemma, St John, Amanda, Wood, Andrew, Wolf, Joshua and Ware, Robert (2024). Preventing adverse events during paediatric cancer treatment: protocol for a multi-site hybrid randomised controlled trial of catheter lock solutions (the CLOCK trial). BMJ Open, 14 (7) e085637, 1-9. doi: 10.1136/bmjopen-2024-085637
2024
Journal Article
An mHealth application for chronic vascular access: consumer led co-creation
Ullman, Amanda J., Gibson, Victoria, Kleidon, Tricia M., Binnewies, Sebastian, Ohira, Ryoma, Marsh, Nicole, McBride, Craig, Winterbourn, Karen, Boyte, Francesca, Cunninghame, Jacqueline, Roberts, Natasha, XU, Grace (Hui), Takashima, Mari, Cooke, Marie, Rickard, Claire M., Byrnes, Joshua and Larsen, Emily (2024). An mHealth application for chronic vascular access: Consumer led co-creation. Journal of Pediatric Nursing, 76, 68-75. doi: 10.1016/j.pedn.2024.02.006
2024
Journal Article
An mHealth application for chronic vascular access: A multi‐method evaluation
Ullman, Amanda J., Larsen, Emily, Gibson, Victoria, Binnewies, Sebastian, Ohira, Ryoma, Marsh, Nicole, Mcbride, Craig, Winterbourn, Karen, Boyte, Francesca, Cunninghame, Jacqueline, Dufficy, Mitchell, Plummer, Karin, Roberts, Natasha, Takashima, Mari, Cooke, Marie, Byrnes, Joshua, Rickard, Claire M. and Kleidon, Tricia M. (2024). An mHealth application for chronic vascular access: A multi‐method evaluation. Journal of Clinical Nursing, 33 (5), 1762-1776. doi: 10.1111/jocn.17034
2024
Journal Article
Learning in the workplace: Development of a simple language statement assessment tool that supports second-level nurse practice
Ohlin, Simone, King, Sue, Takashima, Mari, Ossenberg, Christine and Henderson, Amanda (2024). Learning in the workplace: Development of a simple language statement assessment tool that supports second-level nurse practice. Nurse Education in Practice, 77 103983, 1-7. doi: 10.1016/j.nepr.2024.103983
2024
Journal Article
Methodological progress note: choosing analytic methods for randomized trials
Takashima, Mari D., Ezure, Yukiko, Ullman, Amanda J. and Ware, Robert S. (2024). Methodological progress note: choosing analytic methods for randomized trials. Journal of Hospital Medicine, 19 (4), 312-315. doi: 10.1002/jhm.13315
Supervision
Availability
- Dr Mari Takashima is:
- Available for supervision
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Supervision history
Current supervision
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Master Philosophy
Is there an association between chylothoracies and thromboses in neonates and infants post cardiac surgery?
Associate Advisor
Other advisors: Professor Amanda Ullman
Completed supervision
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2025
Master Philosophy
The Performance of Tunnelled, Non-Cuffed Central Venous Catheters and Peripherally Inserted Central Catheters in Infants
Associate Advisor
Other advisors: Professor Amanda Ullman
Media
Enquiries
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