Overview
Availability
- Professor Steven Lane is:
- Available for supervision
Works
Search Professor Steven Lane’s works on UQ eSpace
2011
Journal Article
AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias
Sykes, Stephen M., Lane, Steven W., Bullinger, Lars, Kalaitzidis, Demetrios, Yusuf, Rushdia, Saez, Borja, Ferraro, Francesca, Mercier, Francois, Singh, Harshabad, Brumme, Kristina M., Acharya, Sanket S., Schoell, Claudia, Tothova, Zuzana, Attar, Eyal C., Froehling, Stefan, DePinho, Ronald A., Armstrong, Scott A., Gilliland, D. Gary and Scadden, David T. (2011). AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias. Cell, 146 (5), 697-708. doi: 10.1016/j.cell.2011.07.032
2011
Conference Publication
Myeloid leukemogenesis driven by aberrant CDX2 expression involves transcriptional repression of KLF4 and deregulated PPAR gamma signaling
Faber, Katrin, Bullinger, Lars, Garding, Angela, Mertens, Daniel, Martin, Daniela, Walcher, Daniel, Doehner, Konstanze, Doehner, Hartmut, Sykes, Stephen M., Claus, Rainer, Plass, Christoph, Lane, Steven W., Scholl, Claudia and Froehling, Stefan (2011). Myeloid leukemogenesis driven by aberrant CDX2 expression involves transcriptional repression of KLF4 and deregulated PPAR gamma signaling. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, 10-13 Dec 2011. Washington, DC, United States: American Society of Hematology.
2011
Conference Publication
Mtor complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis
Kalaitzidis, Demetrios, Sykes, Stephen M., Punt, Natalie, Tang, Yuefeng, Lane, Steven W., Clish, Clary, Gilliland, D. Gary, Scadden, David T., Guertin, David and Armstrong, Scott A. (2011). Mtor complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, 10-13 Dec 2011. Washington, DC, United States: American Society of Hematology.
2011
Conference Publication
Evaluating clonal dominance in a murine knock-in model of Jak2V617F MPN
Mullally, Ann, Poveromo, Luke, Brumme, Kristina, Al-Shahrour, Fatima, Lane, Steven W., Shih, Alan H., Aifantis, Iannis, Levine, Ross L. and Ebert, Benjamin L. (2011). Evaluating clonal dominance in a murine knock-in model of Jak2V617F MPN. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, 10-13 Dec 2011. Washington, DC, United States: American Society of Hematology.
2011
Conference Publication
Pak A proteins are essential for hematopoietic stem/progenitor cell (HSC/P) engraftment through regulation of signaling pathways controlling HSC/P proliferation, survival, migration, and the actin cytoskeleton
Dorrance, Adrienne M., Kosoff', Rachelle, McGuinness, Meaghan, Harris, Chad, De Vita, Serena, Mathieu, Ronald, Lane, Steven W., Milsom, Michael D., Chernoff, Jonathan and Williams, David A. (2011). Pak A proteins are essential for hematopoietic stem/progenitor cell (HSC/P) engraftment through regulation of signaling pathways controlling HSC/P proliferation, survival, migration, and the actin cytoskeleton. 53rd Annual Meeting and Exposition of the American Society of Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis, San Diego, CA, United States, 10-13 Dec 2011. Washington, DC, United States: American Society of Hematology.
2011
Conference Publication
Akt/foxo signaling pathway enforces the differentiation blockade in myeloid leukemias
Sykes, S. M., Lane, S. W., Bullinger, L., Demetrios, K., Yusuf, R., Saez, B., Ferraro, F., Mercier, F., Singh, H., Brumme, K. M., Acharya, S., Scholl, C., Tothova, Z., Attar, E., Froehling, S., DePinho, R. A., Gilliland, D. G., Armstrong, S. A. and Sca, D. T. (2011). Akt/foxo signaling pathway enforces the differentiation blockade in myeloid leukemias. ISEH 40th Annual Scientific Meeting, -, 25 - 28 August 2011. Philadelphia, PA, United States: Elsevier.
2010
Journal Article
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia
Kharas, Michael G., Lengner, Christopher J., Al-Shahrour, Fatima, Bullinger, Lars, Ball, Brian, Zaidi, Samir, Morgan, Kelly, Tam, Winnie, Paktinat, Mahnaz, Okabe, Rachel, Gozo, Maricel, Einhorn, William, Lane, Steven W., Scholl, Claudia, Froehling, Stefan, Fleming, Mark, Ebert, Benjamin L., Gilliland, D. Gary, Jaenisch, Rudolf and Daley, George Q. (2010). Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. Nature Medicine, 16 (8), 903-908. doi: 10.1038/nm.2187
2010
Journal Article
CNS Relapse in Acute Promyeloctyic Leukemia
Housman, Elizabeth, Chang, Priscilla, Lane, Steven W., Blinder, Russell, Galinsky, Ilene, Kesari, Santosh, Ho, Vincent T., Stone, Richard M. and Mullally, Ann (2010). CNS Relapse in Acute Promyeloctyic Leukemia. Journal of Clinical Oncology, 28 (24), E409-E411. doi: 10.1200/JCO.2009.27.1577
2010
Journal Article
Physiological Jak2V617F expression causes a lethal myeloproliferative neoplasm with differential effects on hematopoietis stem and progenitor cells
Mullally, Ann, Lane, Steven W., Ball, Brian, Megerdichian, Christine, Okabe, Rachel, Al-Shahrour, Fatima, Paktinat, Mahnaz, Haydu, J. Erika, Housman, Elizabeth, Lord, Allegra M., Wernig, Gerlinde, Kharas, Michael G., Mercher, Thomas, Kutok, Jeffery L., Gilliland, D. Gary and Ebert, Benjamin L. (2010). Physiological Jak2V617F expression causes a lethal myeloproliferative neoplasm with differential effects on hematopoietis stem and progenitor cells. Cancer Cell, 17 (6), 584-596. doi: 10.1016/j.ccr.2010.05.015
2010
Journal Article
The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS
Lane, Steven W., Sykes, Stephen M., Al-Shahrour, Fatima, Shterental, Sebastian, Paktinat, Mahnaz, Lo Celso, Cristina, Jesneck, Jonathan L., Ebert, Benjamin L., Williams, David A. and Gilliland, D. Gary (2010). The Apcmin mouse has altered hematopoietic stem cell function and provides a model for MPD/MDS. Blood, 115 (17), 3489-3497. doi: 10.1182/blood-2009-11-251728
2010
Journal Article
Leukemia stem cells
Lane, Steven W. and Gilliland, D. Gary (2010). Leukemia stem cells. Seminars in Cancer Biology, 20 (2), 71-76. doi: 10.1016/j.semcancer.2009.12.001
2010
Conference Publication
Characterizing the disease-initiating cell population in a murine model of Jak2V617F+ myeloproliferative neoplasm
Mullally, Ann, Lane, Steven W., Poveromo, Luke, Al-Shahrour, Fatima, Kutok, Jeffery and Ebert, Benjamin L. (2010). Characterizing the disease-initiating cell population in a murine model of Jak2V617F+ myeloproliferative neoplasm. 52nd Annual Meeting of the American Society of Hematology (ASH), Orlando, FL, United States, 4-7 Dec 2010. Washington, DC, United States: American Society of Hematology.
2010
Conference Publication
Leukemia stem cells occupy niches that are physically distinct and independent of the normal constraints that apply to hematopoietic stem cells
Lane, S. W., Sykes, S. M., Ferraro, F., Lin, C. P., Gilliland, D. G., Williams, D. A., Scadden, D. T. and Lo Celso, C. (2010). Leukemia stem cells occupy niches that are physically distinct and independent of the normal constraints that apply to hematopoietic stem cells. 39th Annual Scientific Meeting of the ISEH Society for Hematology and Stem Cells, Melbourne Australia, 15-18 September 2010. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.exphem.2010.07.008
2009
Journal Article
Characterization of the bone marrow immunofluorescence test in childhood autoimmune neutropenia
Lane, S. W., Hassell, P., Kennedy, G. A., Fung, Y. L. and Williams, B. A. (2009). Characterization of the bone marrow immunofluorescence test in childhood autoimmune neutropenia. International Journal of Laboratory Hematology, 31 (5), 567-571. doi: 10.1111/j.1751-553X.2008.01084.x
2009
Journal Article
The leukemic stem cell niche: Current concepts and therapeutic opportunities
Lane, Steven W., Scadden, David T. and Gilliland, D. Gary (2009). The leukemic stem cell niche: Current concepts and therapeutic opportunities. Blood, 114 (6), 1150-1157. doi: 10.1182/blood-2009-01-202606
2009
Conference Publication
WT1 Expression Levels at Diagnosis and as a Marker of Minimal Residual Disease (MRD) in Patients with Acute Myeloid Leukaernia (AML)
Gray, J. X., McMillen, L., Saal, R., Lane, S., Mollee, P., Bird, R., Gill, D. and Marlton, P. (2009). WT1 Expression Levels at Diagnosis and as a Marker of Minimal Residual Disease (MRD) in Patients with Acute Myeloid Leukaernia (AML). 51st Annual Meeting of the American Society of Hematology, New Orleans, LA, United States, 5-8 December 2009. Washington, DC, United States: American Society of Hematology.
2009
Conference Publication
Leukemia stem cells are resistant to in vivo, cell non-autonomous Wnt inhibition.
Lane, Steven W., Lo Celso, Cristina, Sykes, Stephen M., Shterental, Sebastian, Paktinat, Mahnaz, Lin, Charles P., Williams, David A., Scadden, David T. and Gilliland, D. Gary (2009). Leukemia stem cells are resistant to in vivo, cell non-autonomous Wnt inhibition.. 51st Annual Meeting of the American Society of Hematology, New Orleans, LA, United States, 5-8 Dec 2009. Washington, DC, United States: American Society of Hematology.
2008
Journal Article
Prolonged haematological toxicity from the hyper-CVAD regimen: Manifestations, frequency, and natural history in a cohort of 125 consecutive patients
Gill, Saar, Lane, Steven, Crawford, Julie, Cull, Gavin, Joske, David, Joske, David, Marlton, Paula, Mollee, Peter, Prince, Miles and Seymour, John (2008). Prolonged haematological toxicity from the hyper-CVAD regimen: Manifestations, frequency, and natural history in a cohort of 125 consecutive patients. Annals of Hematology, 87 (9), 727-734. doi: 10.1007/s00277-008-0488-6
2008
Journal Article
A 1 log rise in RQ-PCR transcript levels defines molecular relapse in core binding factor accute myeloid leukemia and predicts subsequent morphologic relapse
Lane, Steven, Saal, Russell, Mollee, Peter, Jones, Mark, Grigg, Andrew, Taylor, Kerry, Seymour, John, Kennedy, Glen, Williams, Bronwyn, Grimmett, Karen, Griffiths, Vanessa, Gill, Devinder, Hourigan, Matthew and Marlton, Paula (2008). A 1 log rise in RQ-PCR transcript levels defines molecular relapse in core binding factor accute myeloid leukemia and predicts subsequent morphologic relapse. Leukemia & Lymphoma, 49 (3), 517-523. doi: 10.1080/10428190701817266
2007
Journal Article
Palifermin-induced Acanthosis Nigricans
Lane, S. W., Manoharan, S. and Mollee, P. N. (2007). Palifermin-induced Acanthosis Nigricans. Internal Medicine Journal, 37 (6), 417-418. doi: 10.1111/j.1445-5994.2007.01340.x
Supervision
Availability
- Professor Steven Lane is:
- Available for supervision
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Supervision history
Completed supervision
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2025
Doctor Philosophy
Leukemic transformation STEMming from myeloproliferative neoplasm: Resolving the loss of stem cell heterogeneity
Principal Advisor
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2024
Doctor Philosophy
CRISPR-Cas9 approaches to model Myeloproliferative Neoplasms in vivo.
Principal Advisor
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2019
Doctor Philosophy
Factors that regulate response to chemotherapy in myelodysplastic syndromes and acute myeloid leukaemia
Principal Advisor
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2017
Doctor Philosophy
Maintenance of blood stem cells and the development of haematological malignancies
Principal Advisor
Other advisors: Honorary Professor Geoffrey Hill
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2024
Doctor Philosophy
Targeting the cancer-immune cross talk in Acute Myeloid Leukaemia
Associate Advisor
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2022
Doctor Philosophy
Extracellular vesicle-associated miRNAs and proteins as biomarkers of Non-Small Cell Lung Cancer
Associate Advisor
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2019
Doctor Philosophy
Anti-leukaemia effect of Interferons
Associate Advisor
Other advisors: Honorary Professor Geoffrey Hill
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2017
Doctor Philosophy
Combating Human Immunodeficiency Virus Replication by Gene Therapy
Associate Advisor
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Media
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