Overview
Background
Eoin O'Sullivan, MD, PhD is a Consultant Nephrologist (Senior Staff Specialist) at Metro North, and Lecturer at the Institute for Molecular Bioscience, University of Queensland and Associate at QIMR Berghofer. He has a diverse academic background, with degrees in medicine from University College Cork, Ireland , and a PhD from the University of Edinburgh, UK, where he specialized in the biology of senescence in kidney injury. Dr. O'Sullivan also holds multiple certifications in nephrology and a Masters in medical education.
His research focuses on kidney fibrosis and cellular senescence, with over 52 publications and 10 patent applications. His work has been cited more than 15,000 times, and he has contributed to major advancements in therapeutic strategies for chronic kidney disease. He collaborates extensively with industry partners to develop anti-fibrotic therapies, with several of his discoveries leading to potential new drug targets.
In addition to his research, Dr. O'Sullivan is actively involved in medical education and mentorship, involved with ANZSN Educational an scientific comittees, with national level educational experiences both in Australia and in UK.
Current Research focus:
Theme 1. Senescence
Using single cell RNA-Seq techniques to discover therapeutic targets for people living with Kidney Disease.
Theme 2: Translational Data analysis
Machine learning and AI approaches to clinical data interpretation, prognosis, decision support.
Availability
- Dr Eoin O'Sullivan is:
- Available for supervision
Research interests
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Senescence
Understanding cellular senescence as a biomarkers and therapeutic target for chronic disease outcomes, in particular renal fibrosis/CKD
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single cell RNA-Seq
novel translational approaches to using single cell RNA-Seq, in particular to uncover targets and biomarkers in CKD
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Machine learning and AI
analysis of large volumes of public data ( ECG, clinical parameters, text ) with international collaborations - looking for translational pathways for novel algorithms - in particular focused on Renal and cardiological outcomes,
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Renal Vasculitis
translational focus on clinical data, access to patient data, samples, network of collaborators
Research impacts
Complete list of published works: https://orcid.org/0000-0002-7709-6595
My senescence research program to date has created new knowledge in the field of kidney fibrosis and senescence, documented across multiple publications demonstrating international and cross disciplinary reach attracting over 2,500 citations from 74 countries across 6 continents including major institutions such as University of Oxford, Cambridge, Harvard, Mayo clinic, Johns Hopkins, and several Australian universities. My publications are in the top 10% cited worldwide and appear in the top 10% of journals. Research areas citing this work include cellular biology, computational biology, clinical medicine, and pharmacology (Scival 13/1/24). this program alone places me on the 86th citation percentile for researchers (WOS 6/3/23) Several of these papers are in the top 1% of citations for their ESI subject area (Scival)
Works
Search Professor Eoin O'Sullivan’s works on UQ eSpace
2021
Journal Article
Prolonged SARS-CoV-2 viral shedding in patients with chronic kidney disease
O'Sullivan, Eoin D., Lees, Jennifer S., Howie, Katie L., Pugh, Dan, Gillis, Keith A., Traynor, Jamie P., Macintyre, Iain and Mark, Patrick B. (2021). Prolonged SARS-CoV-2 viral shedding in patients with chronic kidney disease. Nephrology, 26 (4), 328-332. doi: 10.1111/nep.13844
2021
Journal Article
The future role of machine learning in clinical transplantation
Connor, Katie L., O’Sullivan, Eoin D., Marson, Lorna P., Wigmore, Stephen J. and Harrison, Ewen M. (2021). The future role of machine learning in clinical transplantation. Transplantation, 105 (4), 723-735. doi: 10.1097/TP.0000000000003424
2021
Journal Article
Interventions for atypical haemolytic uraemic syndrome
Pugh, Dan, O'Sullivan, Eoin D., Duthie, Fiona A. I., Masson, Philip and Kavanagh, David (2021). Interventions for atypical haemolytic uraemic syndrome. Cochrane Database of Systematic Reviews, 2021 (3) CD012862. doi: 10.1002/14651858.CD012862.pub2
2021
Journal Article
Dexamethasone in Hospitalized Patients with Covid-19
RECOVERY Collaborative Group, Horby, Peter, Lim, Wei Shen, Emberson, Jonathan R., Mafham, Marion, Bell, Jennifer L., Linsell, Louise, Staplin, Natalie, Brightling, Christopher, Ustianowski, Andrew, Elmahi, Einas, Prudon, Benjamin, Green, Christopher, Felton, Timothy, Chadwick, David, Rege, Kanchan, Fegan, Christopher, Chappell, Lucy C., Faust, Saul N., Jaki, Thomas, Jeffery, Katie, Montgomery, Alan, Rowan, Kathryn, Juszczak, Edmund, Baillie, J Kenneth, Haynes, Richard, Landray, Martin J. and O'Sullivan, Eoin (2021). Dexamethasone in Hospitalized Patients with Covid-19. The New England Journal of Medicine, 384 (8), 693-704. doi: 10.1056/NEJMoa2021436
2021
Journal Article
Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
Abaleke, Eugenia, Abbas, Mustafa, Abbasi, Sadia, Abbott, Alfie, Abdelaziz, Ashraf, Abdelbadiee, Sherif, Abdelfattah, Mohamed, Abdul, Basir, Abdul Rasheed, Althaf, Abdul-Kadir, Rezan, Abdulmumeen, Abdulfatahi, Abdulshukkoor, Niyaz, Abdusamad, Kula, Abed El Khaleq, Yazeed, Abedalla, Mai, Abeer Ul Amna, Abeer UA, Aboaba, Adebanke, Abo-Leyah, Hani, Abou-Haggar, Ahmed, Abouibrahim, Mahmoud, Abraham, Miriam, Abraham, Tizzy, Abraheem, Abraheem, Abrams, Judith, Abu, Hyacinth-John, Abu-Arafeh, Ahmad, Abubacker, Syed M, Abung, Akata, Aceampong, Yaa ... RECOVERY Collaborative Group (2021). Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. The Lancet, 397 (10274), 605-612. doi: 10.1016/S0140-6736(21)00149-5
2020
Journal Article
Kidney single-cell atlas reveals myeloid heterogeneity in progression and regression of kidney disease
Conway, Bryan R., O’Sullivan, Eoin D., Cairns, Carolynn, O’Sullivan, James, Simpson, Daniel J., Salzano, Angela, Connor, Katie, Ding, Peng, Humphries, Duncan, Stewart, Kevin, Teenan, Oliver, Pius, Riinu, Henderson, Neil C., Bénézech, Cécile, Ramachandran, Prakash, Ferenbach, David, Hughes, Jeremy, Chandra, Tamir and Denby, Laura (2020). Kidney single-cell atlas reveals myeloid heterogeneity in progression and regression of kidney disease. Journal of the American Society of Nephrology, 31 (12), 2833-2854. doi: 10.1681/ASN.2020060806
2020
Journal Article
Individual patient risk assessment and cost–benefit analysis of patiromer in AMBER
O'Sullivan, Eoin D. and MacIntyre, Iain M. (2020). Individual patient risk assessment and cost–benefit analysis of patiromer in AMBER. The Lancet, 396 (10247), 311-311. doi: 10.1016/S0140-6736(20)30545-6
2020
Journal Article
PPE guidance for covid-19: be honest about resource shortages
O'Sullivan, Eoin D. (2020). PPE guidance for covid-19: be honest about resource shortages. The BMJ, 369 m1507. doi: 10.1136/bmj.m1507
2019
Journal Article
Motivators and barriers to engagement with evidence-based practice among medical and dental trainees from the UK and Republic of Ireland: a national survey
Hong, Bosun, O'Sullivan, Eoin Daniel, Henein, Christin and Jones, Christopher Mark (2019). Motivators and barriers to engagement with evidence-based practice among medical and dental trainees from the UK and Republic of Ireland: a national survey. BMJ Open, 9 (10) 031809, e031809. doi: 10.1136/bmjopen-2019-031809
2019
Journal Article
Cellular senescence in the kidney
Docherty, Marie-Helena, O’Sullivan, Eoin D., Bonventre, Joseph V. and Ferenbach, David A. (2019). Cellular senescence in the kidney. Journal of the American Society of Nephrology, 30 (5), 726-736. doi: 10.1681/ASN.2018121251
2019
Journal Article
Complementary roles for single-nucleus and single-cell RNA sequencing in kidney disease research
O’Sullivan, Eoin D., Mylonas, Katie J., Hughes, Jeremy and Ferenbach, David A. (2019). Complementary roles for single-nucleus and single-cell RNA sequencing in kidney disease research. Journal of the American Society of Nephrology, 30 (4), 712-713. doi: 10.1681/ASN.2019020112
2019
Journal Article
A cognitive forcing tool to mitigate cognitive bias - a randomised control trial
O'Sullivan, Eoin D. and Schofield, Susie J. (2019). A cognitive forcing tool to mitigate cognitive bias - a randomised control trial. BMC Medical Education, 19 (1) 12, 12. doi: 10.1186/s12909-018-1444-3
2018
Journal Article
Conversion of renal abstracts to papers: Published or perished?
Theze, S. A., O'Sullivan, D. M. and O'Sullivan, E. D. (2018). Conversion of renal abstracts to papers: Published or perished?. Nephrology, 23 (2), 193-194. doi: 10.1111/nep.13084
2017
Journal Article
Interventions for atypical haemolytic uraemic syndrome
Pugh, Dan, O'Sullivan, Eoin D., Duthie, Fiona A. I., Masson, Philip and Kavanagh, David (2017). Interventions for atypical haemolytic uraemic syndrome. Cochrane Database of Systematic Reviews, 2017 (11) CD012862. doi: 10.1002/14651858.CD012862
2017
Journal Article
Allosensitization Following Bone Graft
O'Sullivan, E. D., Battle, R. K., Zahra, S., Keating, J. F., Marson, L. P. and Turner, D. M. (2017). Allosensitization Following Bone Graft. American Journal of Transplantation, 17 (8), 2207-2211. doi: 10.1111/ajt.14231
2017
Journal Article
The clinical utility of kinetic glomerular filtration rate
O'Sullivan, Eoin D. and Doyle, Arthur (2017). The clinical utility of kinetic glomerular filtration rate. Clinical Kidney Journal, 10 (2), 202-208. doi: 10.1093/ckj/sfw108
2017
Journal Article
Renal aging: causes and consequences
O'Sullivan, Eoin D., Hughes, Jeremy and Ferenbach, David A. (2017). Renal aging: causes and consequences. Journal of the American Society of Nephrology, 28 (2), 407-420. doi: 10.1681/ASN.2015121308
2016
Journal Article
ISN Forefronts Symposium 2015: the diverse function of macrophages in renal disease
Duthie, Fiona, O'Sullivan, Eoin D. and Hughes, Jeremy (2016). ISN Forefronts Symposium 2015: the diverse function of macrophages in renal disease. Kidney International Reports, 1 (3), 204-209. doi: 10.1016/j.ekir.2016.08.004
2016
Journal Article
Quiz Page August 2016: Skin Lesions in a Dialysis Patient
O Sullivan, Eoin D. and Wardrope, Katrina (2016). Quiz Page August 2016: Skin Lesions in a Dialysis Patient. American Journal of Kidney Diseases, 68 (2), A18-A21. doi: 10.1053/j.ajkd.2016.03.432
2016
Journal Article
Acute respiratory distress syndrome and posterior reversible encephalopathy syndrome following rituximab therapy
Wardrope, Katrina E., Manson, Lynn, Metcalfe, Wendy and O'Sullivan, Eoin D. (2016). Acute respiratory distress syndrome and posterior reversible encephalopathy syndrome following rituximab therapy. Case Reports in Nephrology and Dialysis, 6 (1), 32-39. doi: 10.1159/000444250
Supervision
Availability
- Dr Eoin O'Sullivan is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
The IVCare adaptive platform trial: Towards zero bloodstream infections in IV catheters
Associate Advisor
Other advisors: Dr Jessica Schults, Professor Claire Rickard
Media
Enquiries
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