Overview
Background
I am a physician at RBWH where I did my undergraduate training. I subspecialised in THoracic Medicine with a focus on bronchoscopy. I helped to create a large interventional service here. Part of that inlcuded instituting endobronchial ultrasound ( EBUS), an Australian first, in 2003. This has become standard of care for diagnosing lung cancer.
My research has been centred on how specimens from EBUS can be optimised. I have had strong collaboration with UQCCR, Pathology Queensland and QIMR Berghofer. Our work has expanded on 2 fronts- 1. use of simple cytology smears as the source for panel molecular testing and 2. The expanded role of WES and WGS on these samples.
We have instituted a large Australia wide collaborative network who are collecting samples along with us( The Debutant studies).We have Cancer Council Australia / CCQ/ and NHMRC grants fr these studies
Availability
- Associate Professor David Fielding is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Medicine and Surgery and Medical Science, The University of Queensland
Research interests
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Lung Cancer Genomics
The Debutant study is an Australia wide study ( based at RBWH and UQCCR and QIMR Berghofer) of maximising the utility of specimens for lung cancer genomics when they are collected at biopsy using Endobronchial ultrasound.
Research impacts
Our work has proposed workflow solutions including use of diff quik smears as alternative samples to formalin base samples for genomic study
Our work has built upon the idea of smears being " what yiou see is what you get" as far as samples for genomics, and the way smear microscopy can predict DNA content of the samples, thereby alllowing decision making for genomic testing
We will also continue to build workflow solutions starting from small increasing to large panel, then WES, then WGS, hopefully putting these concepts into the clinic
Works
Search Professor David Fielding’s works on UQ eSpace
2017
Conference Publication
Diffquik Stained Cytology Smears Provide Improved Malignant Cell Dna Yields From Lymph Nodes At Endobronchial Ultrasound Transbronchial Needle Aspiration (Ebus-Tbna)
Fielding, D., Dalley, A., Bashirzadeh, F., Singh, M., Nandakumar, L., Reed, McCart A., Black, D., Waddell, N., Kazakoff, Stephen, Nones, Katia, Pearson, John, Lakhani, S. and Simpson, P. (2017). Diffquik Stained Cytology Smears Provide Improved Malignant Cell Dna Yields From Lymph Nodes At Endobronchial Ultrasound Transbronchial Needle Aspiration (Ebus-Tbna). ANZSRS/TSANZ Annual Scientific Meeting, Canberra, Australia, 24-28 March 2017. Richmond, VIC, Australia: Wiley-Blackwell.
2016
Journal Article
Development of a novel image-based program to teach narrow-band imaging
Dumas, Cedric, Fielding, David, Coles, Timothy and Good, Norm (2016). Development of a novel image-based program to teach narrow-band imaging. Therapeutic Advances in Respiratory Disease, 10 (4), 300-309. doi: 10.1177/1753465816644166
2016
Journal Article
Exercise-induced endobronchial hemorrhage: a rare clinical presentation
Kruavit, Anuk, Jain, Mukesh, Fielding, David and Heraganahally, Subash (2016). Exercise-induced endobronchial hemorrhage: a rare clinical presentation. Respirology Case Reports, 4 (4) e00163, e00163. doi: 10.1002/rcr2.163
2016
Conference Publication
PLEUROSCOPY IS EFFECTIVE IN THE DIAGNOSIS OF BENIGN PLEURAL CONDITIONS
Thirunavukarasu, C., Bashirzadeh, F. and Fielding, D. (2016). PLEUROSCOPY IS EFFECTIVE IN THE DIAGNOSIS OF BENIGN PLEURAL CONDITIONS. HOBOKEN: WILEY-BLACKWELL.
2016
Conference Publication
A NEW BRONCHOSCOPY TEACHING TOOL (A HIGH DEFINITION LAP TOP BASED SIMULATOR-THE CIRCULAR CHECKLIST) SHOWS TRAINING BENEFIT IN A CROSS OVER EVALUATION
Fielding, D., Bashirzadeh, F., Coles, T., Dumas, C. and Salvado, O. (2016). A NEW BRONCHOSCOPY TEACHING TOOL (A HIGH DEFINITION LAP TOP BASED SIMULATOR-THE CIRCULAR CHECKLIST) SHOWS TRAINING BENEFIT IN A CROSS OVER EVALUATION. HOBOKEN: WILEY-BLACKWELL.
2016
Conference Publication
TALC POUDRAGE IS AN EFFECTIVE TREATMENT OPTION FOR PLEURAL EFFUSIONS INCLUDING IN PATIENTS FROM REGIONAL CENTRES WHO ALSO REQUIRE A TISSUE DIAGNOSIS
Thirunavukarasu, C., Bashirzadeh, F. and Fielding, D. (2016). TALC POUDRAGE IS AN EFFECTIVE TREATMENT OPTION FOR PLEURAL EFFUSIONS INCLUDING IN PATIENTS FROM REGIONAL CENTRES WHO ALSO REQUIRE A TISSUE DIAGNOSIS. HOBOKEN: WILEY-BLACKWELL.
2016
Conference Publication
INTER-OBSERVER VARIABILITY IN THE RECOGNITION OF BRONCHIAL SEGMENTAL ANATOMICAL VARIATIONS BETWEEN EXPERIENCED AND TRAINING BRONCHOSCOPISTS
Galt, L., Pahoff, C., Ritchie, A., Duffy, D. and Fielding, D. (2016). INTER-OBSERVER VARIABILITY IN THE RECOGNITION OF BRONCHIAL SEGMENTAL ANATOMICAL VARIATIONS BETWEEN EXPERIENCED AND TRAINING BRONCHOSCOPISTS. HOBOKEN: WILEY-BLACKWELL.
2016
Conference Publication
HIGH INCIDENCE OF THE SEGMENTAL BRONCHIAL ANATOMY VARIATIONS OBSERVED DURING BRONCHOSCOPY IN AN AUSTRALIAN POPULATION
Galt, L., Pahoff, C., Ritchie, A., Duffy, D. and Fielding, D. (2016). HIGH INCIDENCE OF THE SEGMENTAL BRONCHIAL ANATOMY VARIATIONS OBSERVED DURING BRONCHOSCOPY IN AN AUSTRALIAN POPULATION. HOBOKEN: WILEY-BLACKWELL.
2016
Conference Publication
CYTOLOGICAL FINDINGS DUE TO OCCUPATIONAL DUST EXPOSURE IN PATIENTS WITH BENIGN MEDIASTINAL AND HILAR LYMPHADENOPATHY INVESTIGATED WITH ENDOBRONCHIAL ULTRASOUND TRANSBRONCHIAL NEEDLE ASPIRATION (EBUS TBNA)
Pattison, A., Fielding, D., Cook, A., Singh, M. and Nandakumar, L. (2016). CYTOLOGICAL FINDINGS DUE TO OCCUPATIONAL DUST EXPOSURE IN PATIENTS WITH BENIGN MEDIASTINAL AND HILAR LYMPHADENOPATHY INVESTIGATED WITH ENDOBRONCHIAL ULTRASOUND TRANSBRONCHIAL NEEDLE ASPIRATION (EBUS TBNA). HOBOKEN: WILEY-BLACKWELL.
2016
Conference Publication
FIRST CLINICAL APPLICATION OF BRONCHIAL THERMOPLASTY IN AUSTRALIA
Sha, J., Langton, D., Ing, A. and Fielding, D. (2016). FIRST CLINICAL APPLICATION OF BRONCHIAL THERMOPLASTY IN AUSTRALIA. HOBOKEN: WILEY-BLACKWELL.
2016
Conference Publication
CT DETECTION OF VISIBLE ENDOBRONCHIAL ANATOMICAL VARIANTS WITH THE KURIMOTO CT BRONCHIAL BRANCH READING METHOD SHOWS HIGH SPECIFICITY
Fielding, D., Galt, L., Pahoff, C., Ritchie, A., Hundloe, J., Bashirzadeh, F. and Kurimoto, N. (2016). CT DETECTION OF VISIBLE ENDOBRONCHIAL ANATOMICAL VARIANTS WITH THE KURIMOTO CT BRONCHIAL BRANCH READING METHOD SHOWS HIGH SPECIFICITY. HOBOKEN: WILEY-BLACKWELL.
2016
Conference Publication
In the Investigation of Solitary Pulmonary Nodules a Positive Bronchus Sign and Detection of Regional Nodes Greatly Adds to Biopsy Yield and Procedural Efficiency When Comparing Endobronchial Ultrasound and Ct Guided Percutaneous Biopsy
Gibson, G., Fielding, D., Steinke, K., Ravikumar, A., Bashirzadeh, F., Roach, R., Windsor, M. and Ware, R. (2016). In the Investigation of Solitary Pulmonary Nodules a Positive Bronchus Sign and Detection of Regional Nodes Greatly Adds to Biopsy Yield and Procedural Efficiency When Comparing Endobronchial Ultrasound and Ct Guided Percutaneous Biopsy. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA Australia, 1–6 April 2016. Hoboken, NJ United States: Wiley-Blackwell.
2016
Conference Publication
Fdg-Pet/ct Is Sensitive But Not Specific and Outperforms Clinical Risk Predictors in the Investigation of Solitary Pulmonary Nodules in a Thoracic Medicine Referral Centre
Gibson, G., Fielding, D., Steinke, K., Ravikumar, A., Bashirzadeh, F., Roach, R., Windsor, M. and Ware, R. (2016). Fdg-Pet/ct Is Sensitive But Not Specific and Outperforms Clinical Risk Predictors in the Investigation of Solitary Pulmonary Nodules in a Thoracic Medicine Referral Centre. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA Australia, 1–6 April 2016. Hoboken, NJ United States: Wiley-Blackwell.
2016
Conference Publication
Next Generation Sequencing On Endobronchial Ultrasound Transbronchial Needle Aspirate Lymph Node Specimens in Lung Cancer Shows a High Incidence of Mutations and Consistency with Single Gene Testing
Fielding, D., Bashirzadeh, F., Singh, M., Nandakumar, L., Reed, Mccart A., Black, D., Dalley, A., Pearson, J., Nones, K., Waddell, N., Simpson, P. and Lakhani, S. (2016). Next Generation Sequencing On Endobronchial Ultrasound Transbronchial Needle Aspirate Lymph Node Specimens in Lung Cancer Shows a High Incidence of Mutations and Consistency with Single Gene Testing. Thoracic Society of Australia & New Zealand and the Australian & New Zealand Society of Respiratory Science, Annual Scientific Meeting, Perth, WA, Australia, 1-6 April 2016. Wiley. doi: 10.1111/resp.12754_12
2015
Conference Publication
VOC Breath Testing in Squamous Cell Carcinoma (SCC) of Lung and Larynx Shows Distinct Profiles Each of Which Relate to Tumour Burden
Fielding, David, Davis, Mark, Brown, Michael, Dent, Annette, Dickie, Graham, Agnew, Julienne and Hodge, Robert (2015). VOC Breath Testing in Squamous Cell Carcinoma (SCC) of Lung and Larynx Shows Distinct Profiles Each of Which Relate to Tumour Burden. NEW YORK: ELSEVIER SCIENCE INC.
2015
Journal Article
Grey scale texture analysis of endobronchial ultrasound mini probe images for prediction of benign or malignant aetiology
Nguyen, Phan, Bashirzadeh, Farzad, Hundloe, Justin, Salvado, Olivier, Dowson, Nicholas, Ware, Robert, Masters, Ian Brent, Ravi Kumar, Aravind and Fielding, David (2015). Grey scale texture analysis of endobronchial ultrasound mini probe images for prediction of benign or malignant aetiology. Respirology, 20 (6), 960-966. doi: 10.1111/resp.12577
2015
Journal Article
Optical differentiation between malignant and benign lymphadenopathy by EBUS using grey scale texture analysis
Nguyen, Phan and Fielding, David (2015). Optical differentiation between malignant and benign lymphadenopathy by EBUS using grey scale texture analysis. Respirology, 20 (5), 847-848. doi: 10.1111/resp.12548
2015
Journal Article
A new instrument to assess physician skill at chest tube insertion: the TUBE-iCOMPT
Salamonsen, Matthew R., Bashirzadeh, Farzad, Ritchie, Alexander J., Ward, Helen E. and Fielding, David I. K. (2015). A new instrument to assess physician skill at chest tube insertion: the TUBE-iCOMPT. Thorax, 70 (2), 186-188. doi: 10.1136/thoraxjnl-2013-204914
2015
Journal Article
Improved surgical margin definition by Narrow Band Imaging for resection of oral squamous cell carcinoma: a prospective gene expression profiling study
Farah, Camile S., Dalley, Andrew J., Nguyen, Phan, Batstone, Martin, Kordbacheh, Farzaneh, Perry-Keene, Joanna and Fielding, David (2015). Improved surgical margin definition by Narrow Band Imaging for resection of oral squamous cell carcinoma: a prospective gene expression profiling study. Head and Neck, 38 (6), 832-839. doi: 10.1002/hed.23989
2015
Journal Article
Comparison of objective criteria and expert visual interpretation to classify benign and malignant hilar and mediastinal nodes on 18-F FDG PET/CT
Nguyen, Phan, Bhatt, Manoj, Bashirzadeh, Farzad, Hundloe, Justin, Ware, Robert, Fielding, David and Ravi Kumar, Aravind S. (2015). Comparison of objective criteria and expert visual interpretation to classify benign and malignant hilar and mediastinal nodes on 18-F FDG PET/CT. Respirology, 20 (1), 129-137. doi: 10.1111/resp.12409
Supervision
Availability
- Associate Professor David Fielding is:
- Available for supervision
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Supervision history
Current supervision
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Master Philosophy
Second Primary Lung Cancer in HNSCC patients: understanding the high risk patient
Associate Advisor
-
Master Philosophy
Second Primary Lung Cancer in HNSCC patients: understanding the high risk patient
Associate Advisor
Completed supervision
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2015
Doctor Philosophy
Improving Pleural Procedures: Training, Image Analysis and Pleural Manometry
Principal Advisor
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2025
Master Philosophy
Second Primary Lung Cancer in HNSCC patients: understanding the high risk patient
Associate Advisor
-
2017
Doctor Philosophy
The Role of Exhaled Breath Analysis in the Diagnosis and Monitoring of Lung Diseases
Associate Advisor
Other advisors: Professor Kwun Fong, Professor Ian Yang, Associate Professor Paul Zimmerman
Media
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