Associate Professor David Fielding
Associate Professor

David Fielding

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Background

I am a physician at RBWH where I did my undergraduate training. I subspecialised in THoracic Medicine with a focus on bronchoscopy. I helped to create a large interventional service here. Part of that inlcuded instituting endobronchial ultrasound ( EBUS), an Australian first, in 2003. This has become standard of care for diagnosing lung cancer.

My research has been centred on how specimens from EBUS can be optimised. I have had strong collaboration with UQCCR, Pathology Queensland and QIMR Berghofer. Our work has expanded on 2 fronts- 1. use of simple cytology smears as the source for panel molecular testing and 2. The expanded role of WES and WGS on these samples.

We have instituted a large Australia wide collaborative network who are collecting samples along with us( The Debutant studies).We have Cancer Council Australia / CCQ/ and NHMRC grants fr these studies

Availability

Associate Professor David Fielding is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Earth Sciences

Qualifications

  • Bachelor of Medicine and Surgery and Medical Science, The University of Queensland

Research interests

  • Lung Cancer Genomics

    The Debutant study is an Australia wide study ( based at RBWH and UQCCR and QIMR Berghofer) of maximising the utility of specimens for lung cancer genomics when they are collected at biopsy using Endobronchial ultrasound.

Research impacts

Our work has proposed workflow solutions including use of diff quik smears as alternative samples to formalin base samples for genomic study

Our work has built upon the idea of smears being " what yiou see is what you get" as far as samples for genomics, and the way smear microscopy can predict DNA content of the samples, thereby alllowing decision making for genomic testing

We will also continue to build workflow solutions starting from small increasing to large panel, then WES, then WGS, hopefully putting these concepts into the clinic

Search Professor David Fielding’s works on UQ eSpace

143 works between 1977 and 2025
All (143) Journal Article (94) Book Chapter (5) Conference Publication (41) Book (2) Other Outputs (1)

41 - 60 of 143 works

2020

Book Chapter

Future Directions for Endobronchial Ultrasonography

Fielding, David I.K. (2020). Future Directions for Endobronchial Ultrasonography. Endobronchial Ultrasonography. (pp. 187-192) Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/9781119233961.ch16

Future Directions for Endobronchial Ultrasonography

2020

Book Chapter

Endobronchial Ultrasonography for Ground-GlassOpacity Lesions

Fielding, David I.K. (2020). Endobronchial Ultrasonography for Ground-GlassOpacity Lesions. Endobronchial Ultrasonography. (pp. 133-135) Oxford, United Kingdom: John Wiley & Sons. doi: 10.1002/9781119233961.ch11

Endobronchial Ultrasonography for Ground-GlassOpacity Lesions

2019

Journal Article

First human use of a new robotic-assisted fiber optic sensing navigation system for small peripheral pulmonary nodules

Fielding, David I. K., Bashirzadeh, Farzad, Son, Jung Hwa, Todman, Maryann, Chin, Adrian, Tan, Lionel, Steinke, Karin, Windsor, Morgan N. and Sung, Rthur Wai (2019). First human use of a new robotic-assisted fiber optic sensing navigation system for small peripheral pulmonary nodules. Respiration, 98 (2), 142-150. doi: 10.1159/000498951

First human use of a new robotic-assisted fiber optic sensing navigation system for small peripheral pulmonary nodules

2019

Journal Article

Diff-Quik cytology smears from endobronchial ultrasound transbronchial needle aspiration lymph node specimens as a source of DNA for next-generation sequencing instead of cell blocks

Fielding, David, Dalley, Andrew J., Bashirzadeh, Farzad, Singh, Mahendra, Nandakumar, Lakshmy, McCart Reed, Amy E., Black, Debra, Kazakoff, Stephen, Pearson, John V., Nones, Katia, Waddell, Nicola, Lakhani, Sunil R. and Simpson, Peter T. (2019). Diff-Quik cytology smears from endobronchial ultrasound transbronchial needle aspiration lymph node specimens as a source of DNA for next-generation sequencing instead of cell blocks. Respiration, 97 (6), 1-14. doi: 10.1159/000495661

Diff-Quik cytology smears from endobronchial ultrasound transbronchial needle aspiration lymph node specimens as a source of DNA for next-generation sequencing instead of cell blocks

2019

Journal Article

Bronchodilator responsiveness as a predictor of success for bronchial thermoplasty

Langton, David, Ing, Alvin, Fielding, David, Wang, Wei, Plummer, Virginia and Thien, Francis (2019). Bronchodilator responsiveness as a predictor of success for bronchial thermoplasty. Respirology, 24 (1), 63-67. doi: 10.1111/resp.13375

Bronchodilator responsiveness as a predictor of success for bronchial thermoplasty

2019

Journal Article

Chronic Pulmonary Melioidosis Masquerading as lung malignancy diagnosed by EBUS guided sheath technique

Zaw, Kyi Kyi, Wasgewatta, Sanjiwika L., Kwong, Kin Keung, Fielding, David, Heraganahally, Subash S. and Currie, Bart J. (2019). Chronic Pulmonary Melioidosis Masquerading as lung malignancy diagnosed by EBUS guided sheath technique. Respiratory Medicine Case Reports, 28 100894, 1-4. doi: 10.1016/j.rmcr.2019.100894

Chronic Pulmonary Melioidosis Masquerading as lung malignancy diagnosed by EBUS guided sheath technique

2018

Journal Article

Expiratory reactance abnormalities in patients with expiratory dynamic airway collapse: a new application of impulse oscillometry

Fielding, David I., Travers, Justin, Nguyen, Phan, Brown, Michael G., Hartel, Gunter and Morrison, Stephen (2018). Expiratory reactance abnormalities in patients with expiratory dynamic airway collapse: a new application of impulse oscillometry. ERJ Open Research, 4 (4), 00080-2018. doi: 10.1183/23120541.00080-2018

Expiratory reactance abnormalities in patients with expiratory dynamic airway collapse: a new application of impulse oscillometry

2018

Journal Article

EBUS-TBNA cytology specimens are predictive of occupational dust exposure in patients with bilateral mediastinal and hilar lymphadenopathy

Pattison, Andrew, Cook, Alistair, Singh, Mahendra, Nandakumar, Lakshmy, Kumar, Aravind Ravi and Fielding, David (2018). EBUS-TBNA cytology specimens are predictive of occupational dust exposure in patients with bilateral mediastinal and hilar lymphadenopathy. Journal of Occupational and Environmental Medicine, 60 (10), 880-885. doi: 10.1097/JOM.0000000000001388

EBUS-TBNA cytology specimens are predictive of occupational dust exposure in patients with bilateral mediastinal and hilar lymphadenopathy

2018

Journal Article

Distinguishing bronchoscopic changes of mitral stenosis from carcinoma in situ with narrow band imaging

Fielding, David I. and Schuster, Daniel D. (2018). Distinguishing bronchoscopic changes of mitral stenosis from carcinoma in situ with narrow band imaging. Journal of Bronchology & Interventional Pulmonology, 25 (3), 231-234. doi: 10.1097/LBR.0000000000000255

Distinguishing bronchoscopic changes of mitral stenosis from carcinoma in situ with narrow band imaging

2018

Journal Article

Non-small cell lung cancer brain metastasis screening in the era of positron emission tomography-CT staging: current practice and outcomes

Diaz, Mauricio E., Debowski, Maciej, Hukins, Craig, Fielding, David, Fong, Kwun M. and Bettington, Catherine S. (2018). Non-small cell lung cancer brain metastasis screening in the era of positron emission tomography-CT staging: current practice and outcomes. Journal of Medical Imaging and Radiation Oncology, 62 (3), 383-388. doi: 10.1111/1754-9485.12732

Non-small cell lung cancer brain metastasis screening in the era of positron emission tomography-CT staging: current practice and outcomes

2018

Journal Article

Endobronchial ultrasound-guided transbronchial needle aspiration for diagnosis and staging of lung cancer

Fielding, David and Kurimoto, Noriaki (2018). Endobronchial ultrasound-guided transbronchial needle aspiration for diagnosis and staging of lung cancer. Clinics in Chest Medicine, 39 (1), 111-123. doi: 10.1016/j.ccm.2017.11.012

Endobronchial ultrasound-guided transbronchial needle aspiration for diagnosis and staging of lung cancer

2018

Journal Article

Editorial: Tissue is the issue to confirm benign disease at pleuroscopy in lung cancer

Fielding, David (2018). Editorial: Tissue is the issue to confirm benign disease at pleuroscopy in lung cancer. Respirology, 23 (2), 126-127. doi: 10.1111/resp.13225

Editorial: Tissue is the issue to confirm benign disease at pleuroscopy in lung cancer

2017

Journal Article

Risk stratification in the investigation of pulmonary nodules in a high-risk cohort: positron emission tomography/computed tomography outperforms clinical risk prediction algorithms

Gibson, Glenna, Kumar, Aravind Ravi, Steinke, Karin, Bashirzadeh, Farzad, Roach, Rebecca, Windsor, Morgan, Ware, Robert and Fielding, David (2017). Risk stratification in the investigation of pulmonary nodules in a high-risk cohort: positron emission tomography/computed tomography outperforms clinical risk prediction algorithms. Internal Medicine Journal, 47 (12), 1385-1392. doi: 10.1111/imj.13576

Risk stratification in the investigation of pulmonary nodules in a high-risk cohort: positron emission tomography/computed tomography outperforms clinical risk prediction algorithms

2017

Journal Article

A combined hands-on teaching programme and clinical pathway focused on pleural ultrasound and procedure supervision transforms pleural procedure outcomes

Edwards, Timothy, Cook, Alistair, Salamonsen, Matthew, Bashirzadeh, Farzad and Fielding, David (2017). A combined hands-on teaching programme and clinical pathway focused on pleural ultrasound and procedure supervision transforms pleural procedure outcomes. Internal Medicine Journal, 47 (11), 1276-1282. doi: 10.1111/imj.13489

A combined hands-on teaching programme and clinical pathway focused on pleural ultrasound and procedure supervision transforms pleural procedure outcomes

2017

Journal Article

Editorial: Simulation and assessment tools in EBUS TBNA training: What are we waiting for?

Fielding, David (2017). Editorial: Simulation and assessment tools in EBUS TBNA training: What are we waiting for?. Respirology, 22 (8), 1483-1484. doi: 10.1111/resp.13136

Editorial: Simulation and assessment tools in EBUS TBNA training: What are we waiting for?

2017

Journal Article

Next-generation sequencing of endobronchial ultrasound transbronchial needle aspiration specimens in lung cancer

Fielding, David, Dalley, Andrew J., Bashirzadeh, Farzad, Singh, Mahendra, Nandakumar, Lakshmy, Reed, Amy E. McCart, Black, Debra, Kazakoff, Stephen, Nones, Katia, Pearson, John, Waddell, Nic, Lakhani, Sunil R. and Simpson, Peter T. (2017). Next-generation sequencing of endobronchial ultrasound transbronchial needle aspiration specimens in lung cancer. American Journal of Respiratory and Critical Care Medicine, 196 (3), 388-391. doi: 10.1164/rccm.201609-1935LE

Next-generation sequencing of endobronchial ultrasound transbronchial needle aspiration specimens in lung cancer

2017

Journal Article

Bronchial thermoplasty: activations predict response

Langton, David, Sha, Joy, Ing, Alvin, Fielding, David, Thien, Francis and Plummer, Virginia (2017). Bronchial thermoplasty: activations predict response. Respiratory Research, 18 (1) 134. doi: 10.1186/s12931-017-0617-7

Bronchial thermoplasty: activations predict response

2017

Journal Article

Respiratory bronchiolitis-associated interstitial lung disease secondary to electronic nicotine delivery system use confirmed with open lung biopsy

Flower, Mark, Nandakumar, Lakshmy, Singh, Mahendra, Wyld, David, Windsor, Morgan and Fielding, David (2017). Respiratory bronchiolitis-associated interstitial lung disease secondary to electronic nicotine delivery system use confirmed with open lung biopsy. Respirology Case Reports, 5 (3) e00230, e00230. doi: 10.1002/rcr2.230

Respiratory bronchiolitis-associated interstitial lung disease secondary to electronic nicotine delivery system use confirmed with open lung biopsy

2017

Journal Article

Bronchial thermoplasty in severe asthma in Australia

Langton, David, Sha, Joy, Ing, Alvin, Fielding, David and Wood, Erica (2017). Bronchial thermoplasty in severe asthma in Australia. Internal Medicine Journal, 47 (5), 536-541. doi: 10.1111/imj.13372

Bronchial thermoplasty in severe asthma in Australia

2017

Journal Article

Thoracic ultrasound recognition of competence: a position paper of the Thoracic Society of Australia and New Zealand

Williamson, Jonathan P., Twaddell, Scott H., Lee, Y. C. Gary, Salamonsen, Matthew, Hew, Mark, Fielding, David, Nguyen, Phan, Steinfort, Daniel, Hopkins, Peter, Smith, Nicola and Grainge, Christopher (2017). Thoracic ultrasound recognition of competence: a position paper of the Thoracic Society of Australia and New Zealand. Respirology, 22 (2), 405-408. doi: 10.1111/resp.12977

Thoracic ultrasound recognition of competence: a position paper of the Thoracic Society of Australia and New Zealand

Current funding

  • 2021 - 2025
    Improving genomic testing rates for inoperable lung cancer patients
    NHMRC MRFF Genomics Health Futures Mission
    Open grant

Past funding

  • 2018 - 2022
    Streamlining lung cancer diagnosis through genomic testing of cytology smears
    Cancer Australia
    Open grant
  • 2018 - 2020
    Streamlining lung cancer diagnosis through genomic testing of cytology smears
    Cancer Council Queensland
    Open grant
  • 2016 - 2021
    Preparing Australia for Genomic Medicine: A proposal by the Australian Genomics Health Alliance (NHMRC Targeted Call for Research administered by Murdoch Children's Research Institute)
    Murdoch Childrens Research Institute
    Open grant

Availability

Associate Professor David Fielding is:
Available for supervision

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Supervision history

Current supervision

  • Master Philosophy

    Second Primary Lung Cancer in HNSCC patients: understanding the high risk patient

    Associate Advisor

  • Master Philosophy

    Second Primary Lung Cancer in HNSCC patients: understanding the high risk patient

    Associate Advisor

Completed supervision

Enquiries

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