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2014 Journal Article Design, synthesis and biological evaluation of two opioid agonist and Cav2.2 blocker multitarget ligandsMollica, Adriano, Costante, Roberto, Novellino, Ettore, Stefanucci, Azzurra, Pieretti, Stefano, Zador, Ferenc, Samavati, Reza, Borsodi, Anna, Benyhe, Sandor, Vetter, Irina and Lewis, Richard J. (2014). Design, synthesis and biological evaluation of two opioid agonist and Cav2.2 blocker multitarget ligands. Chemical Biology and Drug Design, 86 (2), 156-162. doi: 10.1111/cbdd.12479 |
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2014 Journal Article Ciguatera fish poisoning: a first epidemic in Germany highlights an increasing risk for European countriesMattei, Cesar, Vetter, Irina, Eisenblatter, Anneka, Krock, Bernd, Ebbecke, Martin, Desel, Herbert and Zimmermann, Katharina (2014). Ciguatera fish poisoning: a first epidemic in Germany highlights an increasing risk for European countries. Toxicon, 91 (2), 76-83. doi: 10.1016/j.toxicon.2014.10.016 |
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2014 Conference Publication AMTB, an inhibitor of calcium permeable ion channel TRPM8 and its effect on breast cancer cellsYapa, K., Peters, A. A., Vetter, I., Roberts-Thomson, S. J. and Monteith, G. R. (2014). AMTB, an inhibitor of calcium permeable ion channel TRPM8 and its effect on breast cancer cells. FEBS EMBO 2014 Conference, Paris, France, 30 August - 4 September 2014 . Chichester, West Sussex United Kingdom: Wiley-Blackwell. |
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2014 Journal Article No gain, no pain: NaV1.7 as an analgesic targetKing, Glenn F and Vetter, Irina (2014). No gain, no pain: NaV1.7 as an analgesic target. ACS Chemical Neuroscience, Articles ASAP (9), 749-751. doi: 10.1021/cn500171p |
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2014 Journal Article 2-nitroveratryl as a photocleavable thiol-protecting group for directed disulfide bond formation in the chemical synthesis of insulin.Karas, John A., Scanlon, Denis B., Forbes, Briony E., Vetter, Irina, Lewis, Richard J., Gardiner, James, Separovic, Frances, Wade, John D. and Hossain, Mohammed A. (2014). 2-nitroveratryl as a photocleavable thiol-protecting group for directed disulfide bond formation in the chemical synthesis of insulin.. Chemistry: A European Journal, 20 (31), 9549-9552. doi: 10.1002/chem.201403574 |
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2014 Journal Article Isolation and structural and pharmacological characterization of α-elapitoxin-Dpp2d, an amidated three finger toxin from black mamba venomWang, Ching-I Anderson, Reeks, Timothy, Vetter, Irina, Vergara, Irene, Kovtun, Oleksiy, Lewis, Richard J., Alewood, Paul F. and Durek, Thomas (2014). Isolation and structural and pharmacological characterization of α-elapitoxin-Dpp2d, an amidated three finger toxin from black mamba venom. Biochemistry, 53 (23), 3758-3766. doi: 10.1021/bi5004475 |
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2014 Journal Article A ray of venom: Combined proteomic and transcriptomic investigation of fish venom composition using barb tissue from the blue-spotted stingray (Neotrygon kuhlii)Baumann, Kate, Casewell, Nicholas R., Ali, Syed A., Jackson, Timothy N. W., Vetter, Irina, Dobson, James S., Cutmore, Scott C., Nouwens, Amanda, Lavergne, Vincent and Fry, Bryan G. (2014). A ray of venom: Combined proteomic and transcriptomic investigation of fish venom composition using barb tissue from the blue-spotted stingray (Neotrygon kuhlii). Journal of Proteomics, 109, 188-198. doi: 10.1016/j.jprot.2014.06.004 |
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2014 Journal Article Evolution of separate predation- and defence-evoked venoms in carnivorous cone snailsDutertre, Sébastien, Jin, Ai-Hua, Vetter, Irina, Hamilton, Brett, Sunagar, Kartik, Lavergne, Vincent, Dutertre, Valentin, Fry, Bryan G., Antunes, Agostinho, Venter, Deon J., Alewood, Paul F. and Lewis, Richard J. (2014). Evolution of separate predation- and defence-evoked venoms in carnivorous cone snails. Nature Communications, 5 (3521) 3521, 1-9. doi: 10.1038/ncomms4521 |
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2014 Journal Article MrIC, a novel alpha-conotoxin agonist in the presence of PNU at endogenous alpha-7 nicotinic acetylcholine receptorsJin, Ai-Hua, Vetter, Irina, Dutertre, Sébastien, Abraham, Nikita, Emidio, Nayara B., Inserra, Marco, Murali, Swetha S., Christie, MacDonald J., Alewood, Paul F. and Lewis, Richard J. (2014). MrIC, a novel alpha-conotoxin agonist in the presence of PNU at endogenous alpha-7 nicotinic acetylcholine receptors. Biochemistry, 53 (1), 1-3. doi: 10.1021/bi400882s |
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2014 Conference Publication Discovery of voltage-gated sodium channel inhibitors from tarantula venomsCardoso, F. C., Dekan, Z., Anangi, R., Rosengren, K. J., Erickson, A., Vetter, I., Herzig, V., Alewood, P., King, G. F. and Lewis, R. J. (2014). Discovery of voltage-gated sodium channel inhibitors from tarantula venoms. Venom to Drugs Conference 2014, Kingscliffe, NSW, Australia, 19-23 October 2014. |
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2014 Book Chapter Ciguatera toxins: pharmacology, toxicology and detectionVetter, Irina, Zimmermann, Katharina and Lewis, Richard J. (2014). Ciguatera toxins: pharmacology, toxicology and detection. Seafood and freshwater toxins: pharmacology, physiology, and detection. (pp. 925-950) edited by Luis M. Botana. Boca Raton, FL, United States: CRC Press. doi: 10.1201/b16662-32 |
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2014 Conference Publication Effets de la ciguatoxine P-CTX-2 sur la liberation induite de neuropeptides dans un modele de co-culture keratinocytes-neurones sensorielsL'herondelle, K., Philippe, R., Mignen, O., Vetter, I., Lewis, R. J., Misery, L. and Le Garrec, R. (2014). Effets de la ciguatoxine P-CTX-2 sur la liberation induite de neuropeptides dans un modele de co-culture keratinocytes-neurones sensoriels. 32e Congrès Annuel de Recherche Dermatologique (CARD), Océanopolis, Brest, France, 25-27 June, 2014. Issy les Moulineaux, France: Elsevier Masson. doi: 10.1016/j.annder.2014.04.154 |
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2014 Book Chapter Toxicology of ciguatoxinsVetter, I. and Lewis, R. J. (2014). Toxicology of ciguatoxins. Toxins and biologically active compounds from microalgae: Volume 2: biological effects and risk management. (pp. xx-xx) Boca Raton, FL, United States: CRC Press. doi: 10.1201/b16806-17 |
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2014 Conference Publication AMTB, a TRPM8 channel blocker also inhibits voltage gated sodium channels (Nav) in breast cancer cellsYapa, Kunsala T.D.S, Peters, Amelia A., Vetter, Irina and Roberts-Thomson, Sarah J. (2014). AMTB, a TRPM8 channel blocker also inhibits voltage gated sodium channels (Nav) in breast cancer cells. ASCEPT-MPGPCR Joint Scientific Meeting, Melbourne, VIC, Australia, 7-11 December 2014. |
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2014 Journal Article Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal painDantas De Araujo, Aline, Mobli, Mehdi, Castro, Joel, Harrington, Andrea M., Vetter, Irina, Dekan, Zoltan, Muttenthale, Markus, Wan, JingJing, Lewis, Richard J., King, Glenn F., Brierley, Stuart M. and Alewood, Paul F. (2014). Selenoether oxytocin analogues have analgesic properties in a mouse model of chronic abdominal pain. Nature Communications, 5 (1) 3165, 3165.1-3165.12. doi: 10.1038/ncomms4165 |
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2014 Journal Article Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatinDeuis, Jennifer R., Lim, Yu Ling, Rodrigues de Sousa, Silmara, Lewis, Richard J., Alewood, Paul F., Cabot, Peter J. and Vetter, Irina (2014). Analgesic effects of clinically used compounds in novel mouse models of polyneuropathy induced by oxaliplatin and cisplatin. Neuro-Oncology, 16 (10), 1324-1332. doi: 10.1093/neuonc/nou048 |
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2013 Journal Article Analgesic treatment of ciguatoxin-induced cold allodyniaZimmermann, Katharina, Deuis, Jennifer R., Inserra, Marco C., Collins, Lindon S., Namer, Barbara, Cabot, Peter J., Reeh, Peter W., Lewis, Richard J. and Vetter, Irina (2013). Analgesic treatment of ciguatoxin-induced cold allodynia. Pain, 154 (10), 1999-2006. doi: 10.1016/j.pain.2013.06.015 |
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2013 Journal Article Amplified Cold Transduction in Native Nociceptors by M-Channel InhibitionVetter, Irina, Hein, Alexander, Sattler, Simon, Hessler, Sabine, Touska, Filip, Bressan, Elisangela, Parra, Andres, Hager, Ulrich, Leffler, Andreas, Boukalova, Stepana, Nissen, Matthias, Lewis, Richard J., Belmonte, Carlos, Alzheimer, Christian, Huth, Tobias, Vlachova, Viktorie, Reeh, Peter W. and Zimmermann, Katharina (2013). Amplified Cold Transduction in Native Nociceptors by M-Channel Inhibition. Journal of Neuroscience, 33 (42), 16627-16641. doi: 10.1523/JNEUROSCI.1473-13.2013 |
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2013 Journal Article Isolation and characterization of alpha-conotoxin LsIA with potent activity at nicotinic acetylcholine receptorsInserra, Marco C., Kompella, Shiva N., Vetter, Irina, Brust, Andreas, Daly, Norelle L., Cuny, Hartmut, Craik, David J., Alewood, Paul F., Adams, David J. and Lewis, Richard J. (2013). Isolation and characterization of alpha-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors. Biochemical Pharmacology, 86 (6), 791-799. doi: 10.1016/j.bcp.2013.07.016 |
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2013 Journal Article An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Na(v)1.6 in peripheral pain pathwaysDeuis, Jennifer R., Zimmermann, Katharina, Romanovsky, Andrej A., Possani, Lourival D., Cabot, Peter J., Lewis, Richard J. and Vetter, Irina (2013). An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Na(v)1.6 in peripheral pain pathways. Pain, 154 (9), 1749-1757. doi: 10.1016/j.pain.2013.05.032 |
