2016 Conference Publication Study of the involvement of itch mediators in the neuropeptide release induced by Pacific-Ciguatoxin-2 in a co-culture model of sensory neurons and keratinocytesL'herondelle, K., Philippe, R., Mignen, O., Vetter, I., Lewis, R. J., Misery, L. and Le Garrec, R. (2016). Study of the involvement of itch mediators in the neuropeptide release induced by Pacific-Ciguatoxin-2 in a co-culture model of sensory neurons and keratinocytes. 22nd Meeting of the French-Society-of-Toxinology (SFET), Paris, France, 10-11 December 2014. Kidlington, Oxford, United Kingdom: Pergamon Press. doi: 10.1016/j.toxicon.2016.01.007 |
2016 Book Chapter Ciguatoxin and ciguateraLewis, Richard J. and Vetter, Irina (2016). Ciguatoxin and ciguatera. Marine and freshwater toxins. (pp. 71-92) edited by P. Gopalakrishnakone, Vidal Haddad Jr., Aurelia Tubaro, Euikyung Kim and William R. Kem. Dordrecht, The Netherlands: Springer. doi: 10.1007/978-94-007-6419-4_13 |
2015 Journal Article Vps26B-retromer negatively regulates plasma membrane resensitization of PAR-2Bugarcic, Andrea, Vetter, Irina, Chalmers, Silke, Kinna, Genevieve, Collins, Brett M. and Teasdale, Rohan D. (2015). Vps26B-retromer negatively regulates plasma membrane resensitization of PAR-2. Cell Biology International, 39 (11), 1299-1306. doi: 10.1002/cbin.10508 |
2015 Journal Article Activation of k opioid receptors in cutaneous nerve endings by conorphin-1, a novel subtype-selective conopeptide, does not mediate peripheral analgesiaDeuis, Jennifer, Whately, Ella, Brust, Andreas, Inserra, Marco, Asvadi, Naghmeh Hajarol, Lewis, Richard J., Alewood, Paul F., Cabot, Peter J. and Vetter, Irina (2015). Activation of k opioid receptors in cutaneous nerve endings by conorphin-1, a novel subtype-selective conopeptide, does not mediate peripheral analgesia. ACS Chemical Neuroscience, 6 (10), 1751-1758. doi: 10.1021/acschemneuro.5b00113 |
2015 Journal Article Comparative Venomics Reveals the Complex Prey Capture Strategy of the Piscivorous Cone Snail Conus catusHimaya S.W.A., Jin, Ai-Hua, Dutertre, Sebastien, Giacomotto, Jean, Mohialdeen, Hoshyar, Vetter, Irina, Alewood, Paul F. and Lewis, Richard J. (2015). Comparative Venomics Reveals the Complex Prey Capture Strategy of the Piscivorous Cone Snail Conus catus. Journal of Proteome Research, 14 (10), 4372-4381. doi: 10.1021/acs.jproteome.5b00630 |
2015 Journal Article (-)-Pentylsedinine, a new alkaloid from the leaves of lobelia tupa with agonist activity at nicotinic acetylcholine receptorPaz, Cristian, Becerra, Jose, Silva, Mario, Burgos, Viviana, Heydenreich, Matthias, Schmidt, Bernd, Thu Tran and Vetter, Irina (2015). (-)-Pentylsedinine, a new alkaloid from the leaves of lobelia tupa with agonist activity at nicotinic acetylcholine receptor. Natural Product Communications, 10 (8), 1355-1357. doi: 10.1177/1934578x1501000810 |
2015 Journal Article Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriensCardoso, Fernanda C., Deka, Zoltan, Rosengren, K. Johan, Erickson, Andelain, Vetter, Irina, Deuis, Jennifer R., Herzig, Volker, Alewood, Paul F., King, Glenn F. and Lewis, Richard J. (2015). Identification and characterization of ProTx-III [μ-TRTX-Tp1a], a new voltage-gated sodium channel inhibitor from venom of the tarantula Thrixopelma pruriens. Molecular Pharmacology, 88 (2), 291-303. doi: 10.1124/mol.115.098178 |
2015 Journal Article δ-Conotoxin SuVIA suggests an evolutionary link between ancestral predator defence and the origin of fish-hunting behaviour in carnivorous cone snailsJin, Ai-Hua, Israel, Mathilde R., Inserra, Marco, Smith, Jennifer J., Lewis, Richard J., Alewood, Paul F., Vetter, Irina and Dutertre, Sebastien (2015). δ-Conotoxin SuVIA suggests an evolutionary link between ancestral predator defence and the origin of fish-hunting behaviour in carnivorous cone snails. Proceedings of the Royal Society B: Biological Sciences, 282 (1811) 20150817, 1-8. doi: 10.1098/rspb.2015.0817 |
2015 Journal Article Seven novel modulators of the analgesic target NaV1.7 uncovered using a high-throughput venom-based discovery approachKlint, Julie K., Smith, Jennifer J., Vetter, Irina, Rupasinghe, Darshani B., Er, Sing Yan, Senff, Sebastian, Herzig, Volker, Mobli, Mehdi, Lewis, Richard J., Bosmans, Frank and King, Glenn F. (2015). Seven novel modulators of the analgesic target NaV1.7 uncovered using a high-throughput venom-based discovery approach. British Journal of Pharmacology, 172 (10), 2445-2458. doi: 10.1111/bph.13081 |
2015 Journal Article Inhibition of N-type calcium channels by fluorophenoxyanilide derivativesGleeson, Ellen C., Graham, Janease E., Spiller, Sandro, Vetter, Irina, Lewis, Richard J., Duggan, Peter J. and Tuck, Kellie L. (2015). Inhibition of N-type calcium channels by fluorophenoxyanilide derivatives. Marine Drugs, 13 (4), 2030-2045. doi: 10.3390/md13042030 |
2015 Journal Article α-conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptorsMueller, Alexander, Starobova, Hana, Inserra, Marco C., Jin, Ai-Hua, Deuis, Jennifer R., Dutertre, Sebastien, Lewis, Richard J., Alewood, Paul F., Daly, Norelle L. and Vetter, Irina (2015). α-conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors. Biochemical Pharmacology, 94 (2), 155-163. doi: 10.1016/j.bcp.2015.01.011 |
2015 Journal Article A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseasesColl, Rebecca C., Robertson, Avril A. B., Chae, Jae Jin, Higgins, Sarah C., Muñoz-Planillo, Raúl, Inserra, Marco C., Vetter, Irina, Dungan, Lara S., Monks, Brian G., Stütz, Andrea, Croker, Daniel E., Butler, Mark S., Haneklaus, Moritz, Sutton, Caroline E., Núñez, Gabriel, Latz, Eicke, Kästner, Daniel L., Mills, Kingston H. G., Masters, Seth L., Schroder, Kate, Cooper, Matthew A. and O'Neill, Luke A. J. (2015). A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nature Medicine, 21 (3), 248-257. doi: 10.1038/nm.3806 |
2015 Journal Article Therapeutic opportunities for targeting cold pain pathwaysYin, Kathleen, Zimmermann, Katharina, Vetter, Irina and Lewis, Richard J. (2015). Therapeutic opportunities for targeting cold pain pathways. Biochemical Pharmacology, 93 (2), 125-140. doi: 10.1016/j.bcp.2014.09.024 |
2015 Book Chapter Venoms-based drug discovery: bioassays, electrophysiology, high-throughput screens and target identificationVetter, Irina, Hodgson, Wayne C., Adams, David J. and McIntyre, Peter (2015). Venoms-based drug discovery: bioassays, electrophysiology, high-throughput screens and target identification. Venoms to drugs: venom as a source for the development of human therapeutics. (pp. 97-128) edited by Glenn F. King. Cambridge, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781849737876-00097 |
2015 Book Chapter Research methodsFry, B. G., Undheim, E. A. B., Jackson, T. N. W., Georgieva, D., Vetter, I., Calvete, J. J., Schieb, H., Cribb, B. W., Yang, D. C., Daly, N. L., Manchadi, M. L. Roy, Gutierrez, J. M., Roelants, K., Lomonte, B., Nicholson, G. M., Dziemborowicz, S., Lavergne, V., Ragnarsson, L., Rash, L. D., Mobli, M., Hodgson, W. C., Casewell, N. R., Nouwens, A., Wagstaff, S. C., Ali, S. A., Whitehead, D. L., Herzig, V., Monagle, P., Kurniawan, N. D. ... Sunagar, K. (2015). Research methods. Venomous reptiles and their toxins: evolution, pathophysiology and biodiscovery. (pp. 153-214) New York, NY, United States: Oxford University Press. |
2015 Journal Article Vergiftung durch Tropenfisch: Ciguatera-Epidemie in DeutschlandZimmermann, Katharina, Eisenblätte, Anneka, Vetter, Irina, Ebbecke, Martin, Friedemann, Miriam and Desel, Herbert (2015). Vergiftung durch Tropenfisch: Ciguatera-Epidemie in Deutschland. Deutsche Medizinische Wochenschrift, 140 (2), 125-130. doi: 10.1055/s-0040-100439 |
2015 Conference Publication Rational development of novel analgesics for the treatment of chronic pain: Structure-Function studies of an engineered Nav1.7 blockerRahnama, S., Lachlan, R., Cardoso, F. C., Smith, J., Deuis, J., Vetter, I., King, G. F. and Mobli, M. (2015). Rational development of novel analgesics for the treatment of chronic pain: Structure-Function studies of an engineered Nav1.7 blocker. The 40th Lorne Conference on Protein Structure and Function, Lorne VIC, Australia, 8-12 February 2015. |
2015 Journal Article Feeling hot, feeling cold: TRP channels - a great story unfoldsVetter, Irina, Kym, Philip R. and Szallasi, Arpad (2015). Feeling hot, feeling cold: TRP channels - a great story unfolds. Temperature, 2 (2), 150-151. doi: 10.1080/23328940.2015.1047721 |
2015 Book Chapter Seeing the woods for the trees: understanding venom evolution as a guide for biodiscoveryFry, Bryan G., Koludarov, Ivan, Jackson, Timothy N. W., Holford, Mandë, Terrat, Yves, Casewell, Nicholas R., Undheim, Eivind A. B., Vetter, Irina, Ali, Syed A., Low, Dolyce H. W. and Sunagar, Kartik (2015). Seeing the woods for the trees: understanding venom evolution as a guide for biodiscovery. Venoms to drugs: venom as a source for the development of human therapeutics. (pp. 1-36) edited by Glenn F. King. Cambridge, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781849737876-00001 |
2015 Journal Article Transcriptome and proteome of Conus planorbis identify the nicotinic receptors as primary target for the defensive venomJin, Ai-Hua, Vetter, Irina, Himaya, Siddhihalu W. A., Alewood, Paul F., Lewis, Richard J. and Dutertre, Sébastien (2015). Transcriptome and proteome of Conus planorbis identify the nicotinic receptors as primary target for the defensive venom. Proteomics, 15 (23-24), 4030-4040. doi: 10.1002/pmic.201500220 |