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2019

Journal Article

Common Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development

Fraser, James, Essebier, Alexandra, Brown, Alexander S., Davila, Raul Ayala, Harkins, Danyon, Zalucki, Oressia, Shapiro, Lauren P., Penzes, Peter, Wainwright, Brandon J., Scott, Matthew P., Gronostajski, Richard M., Bodén, Mikael, Piper, Michael and Harvey, Tracey J. (2019). Common Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development. Cerebellum, 19 (1), 89-101. doi: 10.1007/s12311-019-01089-3

Common Regulatory Targets of NFIA, NFIX and NFIB during Postnatal Cerebellar Development

2019

Journal Article

Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells

Robson, Jonathan P., Remke, Marc, Kool, Marcel, Julian, Elaine, Korshunov, Andrey, Pfister, Stefan M., Osborne, Geoffrey W., Taylor, Michael D., Wainwright, Brandon and Reynolds, Brent A. (2019). Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells. PLoS ONE, 14 (1) e0210665, e0210665. doi: 10.1371/journal.pone.0210665

Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells

2018

Journal Article

Granule neuron precursor cell proliferation is regulated by NFIX and intersectin 1 during postnatal cerebellar development

Fraser, James, Essebier, Alexandra, Brown, Alexander S., Davila, Raul Ayala, Sengar, Ameet S., Tu, YuShan, Ensbey, Kathleen S., Day, Bryan W., Scott, Matthew P., Gronostajski, Richard M., Wainwright, Brandon J., Boden, Mikael, Harvey, Tracey J. and Piper, Michael (2018). Granule neuron precursor cell proliferation is regulated by NFIX and intersectin 1 during postnatal cerebellar development. Brain Structure and Function, 224 (2), 811-827. doi: 10.1007/s00429-018-1801-3

Granule neuron precursor cell proliferation is regulated by NFIX and intersectin 1 during postnatal cerebellar development

2018

Journal Article

Elongator mutation in mice induces neurodegeneration and ataxia-like behavior

Kojic, Marija, Gaik, Monika, Kiska, Bence, Salerno-Kochan, Anna, Hunt, Sarah, Tedoldi, Angelo, Mureev, Sergey, Jones, Alun, Whittle, Belinda, Genovesi, Laura A., Adolphe, Christelle, Brown, Darren L., Stow, Jennifer L., Alexandrov, Kirill, Sah, Pankaj, Glatt, Sebastian and Wainwright, Brandon J. (2018). Elongator mutation in mice induces neurodegeneration and ataxia-like behavior. Nature Communications, 9 (1) 3195, 3195. doi: 10.1038/s41467-018-05765-6

Elongator mutation in mice induces neurodegeneration and ataxia-like behavior

2017

Journal Article

Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction

Sheybani-Deloui, Sepideh, Chi, Lijun, Staite, Marian V., Cain, Jason E., Nieman, Brain J., Henkelman, R. Mark, Wainwright, Brandon J., Potter, S. Steven, Bagli, Darius J., Lorenzo, Armando J. and Rosenblum, Norman D. (2017). Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction. Journal of the American Society of Nephrology : JASN, 29 (2), 532-544. doi: 10.1681/ASN.2017050482

Activated Hedgehog-GLI Signaling Causes Congenital Ureteropelvic Junction Obstruction

2017

Journal Article

A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma

Conduit, S. E., Ramaswamy, V., Remke, M., Watkins, D. N., Wainwright, B. J., Taylor, M. D., Mitchell, C. A. and Dyson, J. M. (2017). A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma. Oncogene, 36 (43), 5969-5984. doi: 10.1038/onc.2017.208

A compartmentalized phosphoinositide signaling axis at cilia is regulated by INPP5E to maintain cilia and promote Sonic Hedgehog medulloblastoma

2017

Journal Article

Inhibition of CDK4/6 by palbociclib significantly extends survival in medulloblastoma patient-derived xenograft mouse models

Sangar, Michelle L. Cook, Genovesi, Laura A., Nakamoto, Madison W., Davis, Melissa J., Knobluagh, Sue E., Ji, Pengxiang, Millar, Amanda, Wainwright, Brandon J. and Olson, James M. (2017). Inhibition of CDK4/6 by palbociclib significantly extends survival in medulloblastoma patient-derived xenograft mouse models. Clinical Cancer Research, 23 (19), 5802-5813. doi: 10.1158/1078-0432.CCR-16-2943

Inhibition of CDK4/6 by palbociclib significantly extends survival in medulloblastoma patient-derived xenograft mouse models

2017

Journal Article

Patched1 patterns fibroblast growth factor 10 and forkhead box F1 expression during pulmonary branch formation

Ho, Uda Y. and Wainwright, Brandon J. (2017). Patched1 patterns fibroblast growth factor 10 and forkhead box F1 expression during pulmonary branch formation. Mechanisms of Development, 147, 37-48. doi: 10.1016/j.mod.2017.09.001

Patched1 patterns fibroblast growth factor 10 and forkhead box F1 expression during pulmonary branch formation

2017

Journal Article

Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness

Casas, Bárbara S., Adolphe, Christelle, Lois, Pablo, Navarrete, Nelson, Solís, Natalia, Bustamante, Eva, Gac, Patricio, Cabané, Patricio, Gallegos, Ivan, Wainwright, Brandon J. and Palma, Verónica (2017). Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness. Oncotarget, 8 (48), 84006-84018. doi: 10.18632/oncotarget.21061

Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness

2016

Journal Article

The many faces of elongator in neurodevelopment and disease

Kojic, Marija and Wainwright, Brandon (2016). The many faces of elongator in neurodevelopment and disease. Frontiers in Molecular Neuroscience, 9 (NOV2016) 115, 115. doi: 10.3389/fnmol.2016.00115

The many faces of elongator in neurodevelopment and disease

2016

Journal Article

MicroRNA biogenesis and hedgehog-patched signaling cooperate to regulate an important developmental transition in granule cell development

Constantin, Lena, Constantin, Myrna and Wainwright, Brandon J. (2016). MicroRNA biogenesis and hedgehog-patched signaling cooperate to regulate an important developmental transition in granule cell development. Genetics, 202 (3), 1105-1118. doi: 10.1534/genetics.115.184176

MicroRNA biogenesis and hedgehog-patched signaling cooperate to regulate an important developmental transition in granule cell development

2016

Conference Publication

Basal cell carcinoma development is promoted by ablation of the dermal papilla mesenchymal niche

Villani, R., Sim, S. L., Greaney, J., Wainwright, B. and Khosrotehrani, K. (2016). Basal cell carcinoma development is promoted by ablation of the dermal papilla mesenchymal niche. Asia-Pacific Combined Dermatology Research Conference 2016, Noosa, QLD, Australia, 25–28 August 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12584

Basal cell carcinoma development is promoted by ablation of the dermal papilla mesenchymal niche

2016

Journal Article

Patched receptors sense, interpret and establish an epidermal Hedgehog signalling gradient

Adolphe, Christelle, Junker, Jan Phillipp, Lyubimova, Anna, van Oudenaarden, Alexander and Wainwright, Brandon (2016). Patched receptors sense, interpret and establish an epidermal Hedgehog signalling gradient. Journal of Investigative Dermatology, 137 (1), 179-186. doi: 10.1016/j.jid.2016.06.632

Patched receptors sense, interpret and establish an epidermal Hedgehog signalling gradient

2016

Journal Article

Cell-type-specific expression of NFIX in the developing and adult cerebellum

Fraser, James, Essebier, Alexandra, Gronostajski, Richard M., Boden, Mikael, Wainwright, Brandon J., Harvey, Tracey J. and Piper, Michael (2016). Cell-type-specific expression of NFIX in the developing and adult cerebellum. Brain Structure and Function, 222 (5), 1-20. doi: 10.1007/s00429-016-1340-8

Cell-type-specific expression of NFIX in the developing and adult cerebellum

2016

Conference Publication

Targeting Apoptosis as a Novel Therapy for Myc-Driven Medulloblastoma

Ji, Pengxiang, Genovesi, Laura, He, Yaowu, Hooper, John and Wainwright, Brandon (2016). Targeting Apoptosis as a Novel Therapy for Myc-Driven Medulloblastoma. 17th International Symposium on Pediatric Neuro-Oncology (ISPNO), Liverpool England, 12-15 June 2016. United States: Oxford University Press.

Targeting Apoptosis as a Novel Therapy for Myc-Driven Medulloblastoma

2015

Journal Article

Nuclear factor one transcription factors: divergent functions in developmental versus adult stem cell populations

Harris, Lachlan, Genovesi, Laura A., Gronostajski, Richard M., Wainwright, Brandon J. and Piper, Michael (2015). Nuclear factor one transcription factors: divergent functions in developmental versus adult stem cell populations. Developmental Dynamics, 244 (3), 227-238. doi: 10.1002/dvdy.24182

Nuclear factor one transcription factors: divergent functions in developmental versus adult stem cell populations

2015

Conference Publication

Dominant negative mutation of Sox18 inhibits normal dermal papilla development during embryogenesis and regeneration

Villani, R. M., Hodgson, S., Legrand, J., Greaney, J., Wong, H., Pichol-Thievend, C., Adolphe, C., Wainwright, B., Francois, M. and Khosrotehrani, K. (2015). Dominant negative mutation of Sox18 inhibits normal dermal papilla development during embryogenesis and regeneration. 45th Annual Meeting of the European Society for Dermatological Research, Rotterdam, Netherlands, 9-12 September 2015. London, United Kingdom: Nature Publishing Group. doi: 10.1038/jid.2015.272

Dominant negative mutation of Sox18 inhibits normal dermal papilla development during embryogenesis and regeneration

2015

Journal Article

MicroRNAs promote granule cell expansion in the cerebellum through Gli2

Constantin, Lena and Wainwright, Brandon J. (2015). MicroRNAs promote granule cell expansion in the cerebellum through Gli2. Cerebellum, 14 (6), 688-698. doi: 10.1007/s12311-015-0672-x

MicroRNAs promote granule cell expansion in the cerebellum through Gli2

2014

Journal Article

Zfx facilitates tumorigenesis caused by activation of the hedgehog pathway

Palmer, Colin J., Galan-Caridad, Jose M., Weisberg, Stuart P., Lei, Liang, Esquilin, Jose M., Croft, Gist F., Wainwright, Brandon, Canoll, Peter, Owens, David M. and Reizis, Boris (2014). Zfx facilitates tumorigenesis caused by activation of the hedgehog pathway. Cancer Research, 74 (20), 5914-5924. doi: 10.1158/0008-5472.CAN-14-0834

Zfx facilitates tumorigenesis caused by activation of the hedgehog pathway

2014

Journal Article

Patched 1 and Patched 2 redundancy has a key role in regulating epidermal differentiation

Adolphe, Christelle, Nieuwenhuis, Erica, Villani, Rehan, Li, Zhu Juan, Kaur, Pritinder, Hui, Chi-chung and Wainwright, Brandon J. (2014). Patched 1 and Patched 2 redundancy has a key role in regulating epidermal differentiation. Journal of Investigative Dermatology, 134 (7), 1981-1990. doi: 10.1038/jid.2014.63

Patched 1 and Patched 2 redundancy has a key role in regulating epidermal differentiation