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2021

Journal Article

Ischemic and hemorrhagic stroke among critically ill patients with coronavirus disease 2019: an International Multicenter Coronavirus Disease 2019 Critical Care Consortium study

Cho, Sung-Min, Premraj, Lavienraj, Fanning, Jonathon, Huth, Samuel, Barnett, Adrian, Whitman, Glenn, Arora, Rakesh C., Battaglini, Denise, Porto, Diego Bastos, Choi, HuiMahn, Suen, Jacky, Bassi, Gianluigi Li, Fraser, John F., Robba, Chiara and Griffee, Matthew (2021). Ischemic and hemorrhagic stroke among critically ill patients with coronavirus disease 2019: an International Multicenter Coronavirus Disease 2019 Critical Care Consortium study. Critical Care Medicine, 49 (12), E1223-E1233. doi: 10.1097/CCM.0000000000005209

Ischemic and hemorrhagic stroke among critically ill patients with coronavirus disease 2019: an International Multicenter Coronavirus Disease 2019 Critical Care Consortium study

2021

Journal Article

Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death

Wells, Matthew A., See Hoe, Louise E., Molenaar, Peter, Pedersen, Sanne, Obonyo, Nchafatso G., McDonald, Charles I., Mo, Weilan, Bouquet, Mahè, Hyslop, Kieran, Passmore, Margaret R., Bartnikowski, Nicole, Suen, Jacky Y., Peart, Jason N., McGiffin, David C., Fraser, John F. and on behalf of the Dead Heart Project (2021). Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death. Pharmacological Research, 169 105631, 1-12. doi: 10.1016/j.phrs.2021.105631

Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death

2021

Journal Article

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

ISARIC Clinical Characterisation Group, Li Bassi, Gianluigi, Scarsbrook, Joshua, Shrapnel, Sally, Suen, Jacky and Forsyth, Simon J. (2021). COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study. Infection, 49 (5), 889-905. doi: 10.1007/s15010-021-01599-5

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

2021

Journal Article

Ethical factors determining ECMO allocation during the COVID-19 pandemic

Dao, Bernadine, Savulescu, Julian, Suen, Jacky Y., Fraser, John F. and Wilkinson, Dominic J. C. (2021). Ethical factors determining ECMO allocation during the COVID-19 pandemic. BMC Medical Ethics, 22 (1) 70, 1-12. doi: 10.1186/s12910-021-00638-y

Ethical factors determining ECMO allocation during the COVID-19 pandemic

2021

Conference Publication

Validation of an ovine model of biological ARDS subphenotypes by reproducing mRNA expression profiles

Wildi, K., Hyslop, K., Livingstone, S., Ainola, C., Heinsar, S., Sato, K., Sato, N., Abbate, G., Bouquet, M., Passmore, M., Wilson, E., LiBassi, G., Suen, J. and Fraser, J. (2021). Validation of an ovine model of biological ARDS subphenotypes by reproducing mRNA expression profiles. American Thoracic Society 2021 International Conference, Virtual, 14-19 May 2021. New York, United States: American Thoracic Society. doi: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a2698

Validation of an ovine model of biological ARDS subphenotypes by reproducing mRNA expression profiles

2021

Journal Article

Extracorporeal membrane oxygenation-induced hemolysis: an in vitro study to appraise causative factors

Chan, Chris Hoi Houng, Ki, Katrina K., Zhang, Meili, Asnicar, Cooper, Cho, Hwajin, Ainola, Carmen, Bouquet, Mahe, Heinsar, Silver, Pauls, Jo Philipp, Li Bassi, Gianluigi, Suen, Jacky and Fraser, John F. (2021). Extracorporeal membrane oxygenation-induced hemolysis: an in vitro study to appraise causative factors. Membranes, 11 (5) 313, 313. doi: 10.3390/membranes11050313

Extracorporeal membrane oxygenation-induced hemolysis: an in vitro study to appraise causative factors

2021

Journal Article

Studying the Endothelial Glycocalyx : What Is Missing?

Haymet, Andrew B., Bartnikowski, Nicole, Wood, Emily S., Vallely, Michael P., McBride, Angela, Yacoub, Sophie, Biering, Scott B., Harris, Eva, Suen, Jacky Y. and Fraser, John F. (2021). Studying the Endothelial Glycocalyx : What Is Missing?. Frontiers in Cardiovascular Medicine, 8 647086, 1-13. doi: 10.3389/fcvm.2021.647086

Studying the Endothelial Glycocalyx : What Is Missing?

2021

Conference Publication

Donor heart preservation by hypothermic ex vivo perfusion - improved recipient survival and successful prolongation of ischemic time

Hoe, L. E. See, Wildi, K., Skeggs, K., Bouquet, M., Sato, K., Jung, J., Ainola, C., Hyslop, K., Heinsar, S., Abbate, G., Colombo, S. M., Passmore, M., Wood, E. S., Wells, M., Bartnikowski, N., O'Neill, H., Reid, J., Shuker, T., Haymet, A., Livingstone, S., Sato, N., Obonyo, N., James, L., He, T., McDonald, C., Mullins, D., Engkilde-Pedersen, S., Diab, S., Millar, J. E. ... Fraser, J. F. (2021). Donor heart preservation by hypothermic ex vivo perfusion - improved recipient survival and successful prolongation of ischemic time. ISHLT 41st Annual Meeting, Virtual, 24-28 April 2021. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.healun.2021.01.1864

Donor heart preservation by hypothermic ex vivo perfusion - improved recipient survival and successful prolongation of ischemic time

2021

Journal Article

Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines

Morais, Christudas, Rajandram, Retnagowri, Blakeney, Jade S., Iyer, Abishek, Suen, Jacky Y., Johnson, David W., Gobe, Glenda C., Fairlie, David P. and Vesey, David A. (2021). Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines. PLoS One, 16 (3) e0248983, e0248983. doi: 10.1371/journal.pone.0248983

Expression of protease activated receptor-2 is reduced in renal cell carcinoma biopsies and cell lines

2021

Journal Article

Peritransplant cardio-metabolic and mitochondrial function: the missing piece in donor heart dysfunction and graft failure

Wells, Matthew A., See Hoe, Louise E., Heather, Lisa C., Molenaar, Peter, Suen, Jacky Y., Peart, Jason, McGiffin, David and Fraser, John F. (2021). Peritransplant cardio-metabolic and mitochondrial function: the missing piece in donor heart dysfunction and graft failure. Transplantation, 105 (3), 496-508. doi: 10.1097/tp.0000000000003368

Peritransplant cardio-metabolic and mitochondrial function: the missing piece in donor heart dysfunction and graft failure

2021

Journal Article

Correction to: the discovery of biological subphenotypes in ARDS: a novel approach to targeted medicine?

Wildi, Karin, Livingstone, Samantha, Palmieri, Chiara, LiBassi, Gianluigi, Suen, Jacky and Fraser, John (2021). Correction to: the discovery of biological subphenotypes in ARDS: a novel approach to targeted medicine?. Journal of Intensive Care, 9 (1) 22, 22. doi: 10.1186/s40560-021-00534-y

Correction to: the discovery of biological subphenotypes in ARDS: a novel approach to targeted medicine?

2021

Journal Article

Use of neuromuscular blocking agents in mechanically ventilated patients with COVID-19: a propensity score analysis

Li Bassi, Gianluigi, Gibbons, Kristen, Suen, Jacky Y., Dalton, Heidi J., White, Nicole, Corley, Amanda, Hinton, Samuel, Forsyth, Simon, Laffey, John G., Brodie, Daniel, Burrell, Aidan, Fan, Eddy, Bartlett, Robert, Torres, Antoni, Chiumello, Davide, Elhazmi, Alyaa, Hodgson, Carol, Ichiba, Shingo, Luna, Carlos, Murthy, Srinivas, Nichol, Alistair, Ng, Pauline Yeung, Ogino, Mark, Panigada, Mauro, Pesenti, Antonio and Fraser, John F. (2021). Use of neuromuscular blocking agents in mechanically ventilated patients with COVID-19: a propensity score analysis. SSRN Electronic Journal. doi: 10.2139/ssrn.3773555

Use of neuromuscular blocking agents in mechanically ventilated patients with COVID-19: a propensity score analysis

2021

Journal Article

Assessing potential for aortoiliac vascular injury from VA‐ECMO cannulae: an in vitro particle image velocimetry study

Haymet, A. B., Boone, A., Vallely, M. P., Malfertheiner, M. V., Pauls, J. P., Suen, J. Y. and Fraser, J. F. (2021). Assessing potential for aortoiliac vascular injury from VA‐ECMO cannulae: an in vitro particle image velocimetry study. Artificial Organs, 45 (2) aor.13807, E14-E25. doi: 10.1111/aor.13807

Assessing potential for aortoiliac vascular injury from VA‐ECMO cannulae: an in vitro particle image velocimetry study

2021

Journal Article

PAR2 induces ovarian cancer cell motility by merging three signalling pathways to transactivate EGFR

Jiang, Yuhong, Lim, Junxian, Wu, Kai‐Chen, Xu, Weijun, Suen, Jacky Y. and Fairlie, David P. (2021). PAR2 induces ovarian cancer cell motility by merging three signalling pathways to transactivate EGFR. British Journal of Pharmacology, 178 (4) bph.15332, 913-932. doi: 10.1111/bph.15332

PAR2 induces ovarian cancer cell motility by merging three signalling pathways to transactivate EGFR

2021

Journal Article

The discovery of biological subphenotypes in ARDS: a novel approach to targeted medicine?

Wildi, Karin, Livingstone, Samantha, Palmieri, Chiara, LiBassi, Gianluigi, Suen, Jacky and Fraser, John (2021). The discovery of biological subphenotypes in ARDS: a novel approach to targeted medicine?. Journal of Intensive Care, 9 (1) 14, 1-9. doi: 10.1186/s40560-021-00528-w

The discovery of biological subphenotypes in ARDS: a novel approach to targeted medicine?

2021

Journal Article

Current understanding of leukocyte phenotypic and functional modulation during extracorporeal membrane oxygenation: a narrative review

Ki, Katrina K., Millar, Jonathan E., Langguth, Daman, Passmore, Margaret R., McDonald, Charles I., Shekar, Kiran, Shankar-Hari, Manu, Cho, Hwa Jin, Suen, Jacky Y. and Fraser, John F. (2021). Current understanding of leukocyte phenotypic and functional modulation during extracorporeal membrane oxygenation: a narrative review. Frontiers in Immunology, 11 600684, 600684. doi: 10.3389/fimmu.2020.600684

Current understanding of leukocyte phenotypic and functional modulation during extracorporeal membrane oxygenation: a narrative review

2021

Journal Article

The use of extracorporeal membrane oxygenation in children with acute fulminant myocarditis

Heinsar, Silver, Raman, Sainath, Suen, Jacky Y., Cho, Hwa Jin and Fraser, John F. (2021). The use of extracorporeal membrane oxygenation in children with acute fulminant myocarditis. Clinical and Experimental Pediatrics, 64 (5), 188-195. doi: 10.3345/cep.2020.00836

The use of extracorporeal membrane oxygenation in children with acute fulminant myocarditis

2020

Journal Article

Characterising pre-clinical sub-phenotypic models of Acute Respiratory Distress Syndrome: an experimental ovine study

Millar, Jonathan E., Wildi, Karin, Bartnikowski, Nicole, Bouquet, Mahe, Hyslop, Kieran, Passmore, Margaret R., Ki, Katrina K., See Hoe, Louise E., Obonyo, Nchafatso G., Neyton, Lucile, Pedersen, Sanne, Rozencwajg, Sacha, Baillie, J. Kenneth, Li Bassi, Gianluigi, Suen, Jacky Y, McAuley, Daniel F. and Fraser, John F. (2020). Characterising pre-clinical sub-phenotypic models of Acute Respiratory Distress Syndrome: an experimental ovine study.

Characterising pre-clinical sub-phenotypic models of Acute Respiratory Distress Syndrome: an experimental ovine study

2020

Journal Article

Design and rationale of the COVID-19 Critical Care Consortium international, multicentre, observational study

Bassi, Gianluigi Li, Suen, Jacky, Barnett, Adrian Gerard, Corley, Amanda, Millar, Jonathan, Fanning, Jonathon, Lye, India, Colombo, Sebastiano, Wildi, Karin, Livingstone, Samantha, Abbate, Gabriella, Hinton, Samuel, Liquet, Benoit, Shrapnel, Sally, Dalton, Heidi and Fraser, John F. (2020). Design and rationale of the COVID-19 Critical Care Consortium international, multicentre, observational study. BMJ Open, 10 (12) e041417, 1-6. doi: 10.1136/bmjopen-2020-041417

Design and rationale of the COVID-19 Critical Care Consortium international, multicentre, observational study

2020

Journal Article

The effect of hyperoxia on inflammation and platelet responses in an ex vivo extracorporeal membrane oxygenation circuit

Passmore, Margaret R., Ki, Katrina K., Chan, Chris H. H., Lee, Talvin, Bouquet, Mahé, Wood, Emily S., Raman, Sainath, Rozencwajg, Sacha, Burrell, Aidan J. C., McDonald, Charles I., Langguth, Daman, Shekar, Kiran, Malfertheiner, Maximilian V., Fraser, John F. and Suen, Jacky Y. (2020). The effect of hyperoxia on inflammation and platelet responses in an ex vivo extracorporeal membrane oxygenation circuit. Artificial Organs, 44 (12) aor.13771, 1276-1285. doi: 10.1111/aor.13771

The effect of hyperoxia on inflammation and platelet responses in an ex vivo extracorporeal membrane oxygenation circuit