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2019

Journal Article

Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models

Millar, Jonathan E., Bartnikowski, Nicole, von Bahr, Viktor, Malfertheiner, Maximilian V., Obonyo, Nchafatso G., Belliato, Mirko, Suen, Jacky Y., Combes, Alain, McAuley, Daniel F., Lorusso, Roberto and Fraser, John F. (2019). Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models. Intensive Care Medicine Experimental, 7 (1) 18, 18. doi: 10.1186/s40635-019-0232-7

Extracorporeal membrane oxygenation (ECMO) and the acute respiratory distress syndrome (ARDS): a systematic review of pre-clinical models

2019

Journal Article

Endothelialized flow models for blood transfusion research

Ng, Monica S. Y., Suen, Jacky Y., Tung, John-Paul and Fraser, John F. (2019). Endothelialized flow models for blood transfusion research. Haematologica, 104 (3), 428-434. doi: 10.3324/haematol.2018.205203

Endothelialized flow models for blood transfusion research

2019

Journal Article

Neuron specific enolase and matrix metalloproteinase 9 signal perioperative silent brain infarction during or after transcatheter aortic valve implantation

Fanning, Jonathon P., Hoe, Louise E. See, Passmore, Margaret R., Barnett, Adrian G., Obonyo, Nchafatso G., Millar, Jonathan E., Wesley, Allan J., Suen, Jacky Y. and Fraser, John F. (2019). Neuron specific enolase and matrix metalloproteinase 9 signal perioperative silent brain infarction during or after transcatheter aortic valve implantation. The American Journal of Cardiology, 123 (3), 434-439. doi: 10.1016/j.amjcard.2018.10.022

Neuron specific enolase and matrix metalloproteinase 9 signal perioperative silent brain infarction during or after transcatheter aortic valve implantation

2019

Journal Article

Pre-clinical study protocol: Blood transfusion in endotoxaemic shock

Obonyo, Nchafatso G., Byrne, Liam, Tung, John-Paul, Simonova, Gabriela, Diab, Sara D., Dunster, Kimble R., Passmore, Margaret R., Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Mohd H., Pimenta, Leticia P., Millar, Jonathan E., Fanning, Jonathon P., Van Haren, Frank, Anstey, Chris M., Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John F. (2019). Pre-clinical study protocol: Blood transfusion in endotoxaemic shock. MethodsX, 6, 1124-1132. doi: 10.1016/j.mex.2019.05.005

Pre-clinical study protocol: Blood transfusion in endotoxaemic shock

2019

Conference Publication

Characterisation of cardiac neurohormonal and inflammatory changes induced by brain death in a novel ovine heart transplant model

Hoe, L. See, Shuker, T., Bartnikowski, N., Passmore, M., Bouquet, M., Obonyo, N., Engkilde-Pedersen, S., McDonald, C., Wells, M., Boon, A., Hyslop, K., James, L., Wildi, K., Cullen, L., Bassi, G. Li, Suen, J., McGiffin, D. and Fraser, J. (2019). Characterisation of cardiac neurohormonal and inflammatory changes induced by brain death in a novel ovine heart transplant model. 67th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 13th Annual Australia and New Zealand Endovascular Therapies Meeting, Adelaide, Australia, 8-11 August 2019. chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2019.06.074

Characterisation of cardiac neurohormonal and inflammatory changes induced by brain death in a novel ovine heart transplant model

2018

Journal Article

Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock

Passmore, Margaret R., Byrne, Liam, Obonyo, Nchafatso G., See Hoe, Louise E., Boon, Ai-Ching, Diab, Sara D., Dunster, Kimble R., Bisht, Kavita, Tung, John-Paul, Fauzi, Mohd H., Narula, Monica, Pedersen, Sanne E., Esguerra-Lallen, Arlanna, Simonova, Gabriela, Sultana, Annette, Anstey, Chris M., Shekar, Kiran, Maitland, Kathryn, Suen, Jacky Y. and Fraser, John F. (2018). Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock. Respiratory Research, 19 (1) 231, 231. doi: 10.1186/s12931-018-0935-4

Inflammation and lung injury in an ovine model of fluid resuscitated endotoxemic shock

2018

Journal Article

Recruitment manoeuvres dislodge mucus towards the distal airways in an experimental model of severe pneumonia

Li Bassi, G., Comaru, T., Martí, D., Xiol, E. A., Chiurazzi, C., Travierso, C., Carbonara, M., Ranzani, O. T., Amaro, R., Frigola, G., Fuster, C., Saco, M. A., Zanella, A., De Rosa, F., Rigol, M., Fernandez, L., Luque, N., Ramirez, J., Blasi, F., Suen, J., Fraser, J. and Torres, A. (2018). Recruitment manoeuvres dislodge mucus towards the distal airways in an experimental model of severe pneumonia. British Journal of Anaesthesia, 122 (2), 269-276. doi: 10.1016/j.bja.2018.07.039

Recruitment manoeuvres dislodge mucus towards the distal airways in an experimental model of severe pneumonia

2018

Conference Publication

Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation

Fanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, See Hoe, Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Hashairi Fauzi, Mohd, Pretti Pimenta, Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation. American Heart Association's 2018 Scientific Sessions, Chicago, IL United States, 10-12 November 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins. doi: 10.1161/circ.138.suppl_1.17116

Packed Red Cell Age Associated With Adverse Cardiovascular Changes in an Ovine Model of Septic Shock Resuscitation

2018

Journal Article

Transfusion of packed red blood cells at the end of shelf life is associated with increased risk of mortality - a pooled patient data analysis of 16 observational trials

Ng, Monica S. Y., David, Michael, Middelburg, Rutger A., Ng, Angela S. Y., Suen, Jacky Y., Tung, John-Paul and Fraser, John F. (2018). Transfusion of packed red blood cells at the end of shelf life is associated with increased risk of mortality - a pooled patient data analysis of 16 observational trials. Haematologica, 103 (9), haematol.2018.191932-1548. doi: 10.3324/haematol.2018.191932

Transfusion of packed red blood cells at the end of shelf life is associated with increased risk of mortality - a pooled patient data analysis of 16 observational trials

2018

Journal Article

Administration of mesenchymal stem cells during ECMO results in a rapid decline in oxygenator performance

Millar, Jonathan Edward, von Bahr, Viktor, Malfertheiner, Maximillian V., Ki, Katrina K., Redd, Meredith A., Bartnikowski, Nicole, Suen, Jacky Y., McAuley, Danny Francis and Fraser, John F. (2018). Administration of mesenchymal stem cells during ECMO results in a rapid decline in oxygenator performance. Thorax, 74 (2), 1-3. doi: 10.1136/thoraxjnl-2017-211439

Administration of mesenchymal stem cells during ECMO results in a rapid decline in oxygenator performance

2018

Journal Article

Differential immunological profiles herald magnetic resonance imaging-defined perioperative cerebral infarction

Fanning, Jonathon P., See Hoe, Louise E., Passmore, Margaret R., Barnett, Adrian G., Rolfe, Barbara E., Millar, Jonathan E., Wesley, Allan J., Suen, Jacky and Fraser, John F. (2018). Differential immunological profiles herald magnetic resonance imaging-defined perioperative cerebral infarction. Therapeutic Advances in Neurological Disorders, 11, 1756286418759493. doi: 10.1177/1756286418759493

Differential immunological profiles herald magnetic resonance imaging-defined perioperative cerebral infarction

2018

Journal Article

A potent antagonist of protease-activated receptor 2 that inhibits multiple signaling functions in human cancer cells

Jiang, Yuhong, Yau, Mei-Kwan, Lim, Junxian, Wu, Kai-Chen, Xu, Weijun, Suen, Jacky Y and Fairlie, David P (2018). A potent antagonist of protease-activated receptor 2 that inhibits multiple signaling functions in human cancer cells. The Journal of pharmacology and experimental therapeutics, 364 (2), 246-257. doi: 10.1124/jpet.117.245027

A potent antagonist of protease-activated receptor 2 that inhibits multiple signaling functions in human cancer cells

2018

Conference Publication

Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation

Fanning, Jonathon P., Obonyo, Nchafatso G., Tung, John-Paul, Byrne, Liam, Simonova, Gabriela, Diab, Sara, Dunster, Kimble, Passmore, Margaret, Boon, Ai-Ching, Hoe, See Louise, Engkilde-Pedersen, Sanne, Esguerra-Lallen, Arlanna, Fauzi, Hashairi Mohd, Pretti, Pimenta Leticia, Millar, Jonathan, Anstey, Christopher, van Haren, Frank, Cullen, Louise, Suen, Jacky, Shekar, Kiran, Maitland, Kathryn and Fraser, John (2018). Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation. -, -, 2018. Philadelphia, PA United States: Lippincott Williams & Wilkins.

Packed red cell age associated with adverse cardiovascular changes in an ovine model of septic shock resuscitation

2018

Conference Publication

Development of an ovine model of dilated cardiomyopathy to facilitate clinically translational research

Bartnikowski, N., Obonyo, N., Pedersen, S., Wells, M., Millar, J., Raffel, O., Suen, J., Gregory, S., Haqqani, H. and Fraser, J. (2018). Development of an ovine model of dilated cardiomyopathy to facilitate clinically translational research. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, QLD Australia, 2 - 5 August 2018. Chatswood, NSW Australia: Elsevier . doi: 10.1016/j.hlc.2018.06.110

Development of an ovine model of dilated cardiomyopathy to facilitate clinically translational research

2018

Conference Publication

PAR-2 does not contribute to tubular damage or renal fibrosis in the obstructed kidney

Han, Y., Ma, F., Ozols, E., Chew, P., Vesey, D., Gobe, G., Morais, C., Lohman, R., Suen, J., Fairlie, D. and Nikolic-Paterson, D. (2018). PAR-2 does not contribute to tubular damage or renal fibrosis in the obstructed kidney. 54th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology (ANZSN), Sydney, Australia, 8–12 September 2018. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/nep.13441

PAR-2 does not contribute to tubular damage or renal fibrosis in the obstructed kidney

2018

Conference Publication

Development of an ovine model of heart transplantation following 24-hour brain stem death

See Hoe, L., Engkilde-Pedersen, S., Obonyo, N., Wells, M., Boon, C., Bartnikowski, N., Passmore, M., McDonald, C., Black, D., Molenaar, P., Diab, S., Suen, J., Marasco, S., McGiffin, D. and Fraser, J. (2018). Development of an ovine model of heart transplantation following 24-hour brain stem death. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, Australia, 2-5 August 2018. Chatswood, NSW, Australia: Elsevier . doi: 10.1016/j.hlc.2018.06.111

Development of an ovine model of heart transplantation following 24-hour brain stem death

2018

Conference Publication

Inflammatory cytokine profiles in 24-hour brain stem death model

Boon, A. C., Hoe, L. E. See, Pederson, S. E., Obonyo, N. G., Wells, M. A., Bartnikowski, N. J., Passmore, M. R., Marshall, L., James, L., Tung, J., Suen, J. Y., Macdonald, P. S., McGiffin, D. C. and Fraser, J. F. (2018). Inflammatory cytokine profiles in 24-hour brain stem death model. 38th Annual Meeting and Scientific Sessions of the International-Society-for-Heart-and-Lung-Transplantation (ISHLT), Nice, France, 11-14 April 2018. Philadelphia, PA United States: Elsevier. doi: 10.1016/j.healun.2018.01.506

Inflammatory cytokine profiles in 24-hour brain stem death model

2018

Conference Publication

Neuron specific enolase and matrix metaloproteinase 9 signal silent brain infarction associated with TAVI

Fanning, Jonathon P., Hoe, See Louise E., Passmore, Margaret R., Barnett, Adrian G., Obonyo, Nchafatso G., Millar, Jonathan E., Suen, Jacky Y. and Fraser, John F. (2018). Neuron specific enolase and matrix metaloproteinase 9 signal silent brain infarction associated with TAVI. Philadelphia, PA, United States: Lippincott Williams & Wilkins.

Neuron specific enolase and matrix metaloproteinase 9 signal silent brain infarction associated with TAVI

2017

Journal Article

Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a

Lohman, Rink-Jan, Hamidon, Johan K., Reid, Robert C., Rowley, Jessica A., Yau, Mei-Kwan, Halili, Maria A., Nielsen, Daniel S., Lim, Junxian, Wu, Kai-Chen, Loh, Zhixuan, Do, Anh, Suen, Jacky Y., Iyer, Abishek and Fairlie, David P. (2017). Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a. Nature Communications, 8 (1) 351, 351. doi: 10.1038/s41467-017-00414-w

Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a

2017

Journal Article

Acquired von willebrand syndrome in respiratory extracorporeal life support: A systematic review of the literature

Malfertheiner, M. V., Pimenta, L. P., Von Bahr, V., Millar, J. E., Obonyo, N. G., Suen, J. Y., Pellegrino, V. and Fraser, J. F. (2017). Acquired von willebrand syndrome in respiratory extracorporeal life support: A systematic review of the literature. Critical Care and Resuscitation, 19, 45-52.

Acquired von willebrand syndrome in respiratory extracorporeal life support: A systematic review of the literature