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2022

Journal Article

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381, 1-16. doi: 10.1126/scitranslmed.abj2381

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

2022

Journal Article

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

Blaskovich, Mark A.T., Hansford, Karl A., Butler, Mark S., Ramu, Soumya, Kavanagh, Angela M., Jarrad, Angie M., Prasetyoputri, Anggia, Pitt, Miranda E., Huang, Johnny X., Lindahl, Fredrik, Ziora, Zyta M., Bradford, Tanya, Muldoon, Craig, Rajaratnam, Premraj, Pelingon, Ruby, Edwards, David J., Zhang, Bing, Amado, Maite, Elliott, Alysha G., Zuegg, Johannes, Coin, Lachlan, Woischnig, Anne-Kathrin, Khanna, Nina, Breidenstein, Elena, Stincone, Anna, Mason, Clive, Khan, Nawaz, Cho, Hye-Kyung, Karau, Melissa J. ... Cooper, Matthew A. (2022). A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections. Science Translational Medicine, 14 (662) abj2381. doi: 10.1126/scitranslmed.abj238

A lipoglycopeptide antibiotic for Gram-positive biofilm-related infections

2022

Journal Article

Investigations into the membrane activity of arenicin antimicrobial peptide AA139

Edwards, Ingrid A., Henriques, Sónia T., Blaskovich, Mark A.T., Elliott, Alysha G. and Cooper, Matthew A. (2022). Investigations into the membrane activity of arenicin antimicrobial peptide AA139. Biochimica et Biophysica Acta - General Subjects, 1866 (8) 130156, 130156. doi: 10.1016/j.bbagen.2022.130156

Investigations into the membrane activity of arenicin antimicrobial peptide AA139

2022

Journal Article

N-Alkyl-2-quinolonopyrones demonstrate antimicrobial activity against ESKAPE pathogens including Staphylococcus aureus

Moynihan, Eoin, Mackey, Katrina, Blaskovich, Mark A. T., Reen, F. Jerry and McGlacken, Gerard (2022). N-Alkyl-2-quinolonopyrones demonstrate antimicrobial activity against ESKAPE pathogens including Staphylococcus aureus. ACS Medicinal Chemistry Letters, 13 (8), 1358-1362. doi: 10.1021/acsmedchemlett.2c00185

N-Alkyl-2-quinolonopyrones demonstrate antimicrobial activity against ESKAPE pathogens including Staphylococcus aureus

2022

Journal Article

Fast bacterial growth reduces antibiotic accumulation and efficacy

Łapińska, Urszula, Voliotis, Margaritis, Lee, Ka Kiu, Campey, Adrian, Stone, Rhia M. L., Tuck, Brandon, Phetsang, Wanida, Zhang, Bing, Tsaneva-Atanasova, Krasimira, Blaskovich, Mark A. T. and Pagliara, Stefano (2022). Fast bacterial growth reduces antibiotic accumulation and efficacy. eLife, 11 e74062, 1-33. doi: 10.7554/ELIFE.74062

Fast bacterial growth reduces antibiotic accumulation and efficacy

2022

Journal Article

Loss of β-ketoacyl acyl carrier protein synthase III activity restores multidrug-resistant escherichia coli sensitivity to previously ineffective antibiotics

Hong, Yaoqin, Qin, Jilong, Verderosa, Anthony D., Hawas, Sophia, Zhang, Bing, Blaskovich, Mark A. T., Cronan, John E. and Totsika, Makrina (2022). Loss of β-ketoacyl acyl carrier protein synthase III activity restores multidrug-resistant escherichia coli sensitivity to previously ineffective antibiotics. mSphere, 7 (3), e0011722. doi: 10.1128/msphere.00117-22

Loss of β-ketoacyl acyl carrier protein synthase III activity restores multidrug-resistant escherichia coli sensitivity to previously ineffective antibiotics

2022

Journal Article

Statistical evaluation of cow-dung derived activated biochar for phenol adsorption: adsorption isotherms, kinetics, and thermodynamic studies

Jain, Marut, Khan, Sadaf Aiman, Sahoo, Abhisek, Dubey, Prashant, Pant, Kamal Kishore, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2022). Statistical evaluation of cow-dung derived activated biochar for phenol adsorption: adsorption isotherms, kinetics, and thermodynamic studies. Bioresource Technology, 352 127030, 127030. doi: 10.1016/j.biortech.2022.127030

Statistical evaluation of cow-dung derived activated biochar for phenol adsorption: adsorption isotherms, kinetics, and thermodynamic studies

2022

Conference Publication

Nanoparticle-enhanced digitof for detection of e. coli directly from urine

Kc, S., Venema, T., Parchen, R., Coin, L. and Blaskovich, M. (2022). Nanoparticle-enhanced digitof for detection of e. coli directly from urine. IFCC WorldLab Congress, Seoul, South Korea, 26-30 June 2022. Amsterdam, Netherlands: Elsevier. doi: 10.1016/j.cca.2022.04.818

Nanoparticle-enhanced digitof for detection of e. coli directly from urine

2022

Journal Article

Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates

Medina-Franco, José L., López-López, Edgar, Andrade, Emma, Ruiz-Azuara, Lena, Frei, Angelo, Guan, Davy, Zuegg, Johannes and Blaskovich, Mark A.T. (2022). Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates. Drug Discovery Today, 27 (5), 1420-1430. doi: 10.1016/j.drudis.2022.02.021

Bridging informatics and medicinal inorganic chemistry: toward a database of metallodrugs and metallodrug candidates

2022

Journal Article

Mechanisms underlying synergistic killing of Polymyxin B in combination with cannabidiol against Acinetobacter baumannii: a metabolomic study

Hussein, Maytham, Allobawi, Rafah, Levou, Irini, Blaskovich, Mark A. T., Rao, Gauri G., Li, Jian and Velkov, Tony (2022). Mechanisms underlying synergistic killing of Polymyxin B in combination with cannabidiol against Acinetobacter baumannii: a metabolomic study. Pharmaceutics, 14 (4) 786, 786. doi: 10.3390/pharmaceutics14040786

Mechanisms underlying synergistic killing of Polymyxin B in combination with cannabidiol against Acinetobacter baumannii: a metabolomic study

2022

Journal Article

Amino alcohols as potential antibiotic and antifungal leads

Baker, Jennifer R., Cossar, Peter J., Blaskovich, Mark A. T., Elliott, Alysha G., Zuegg, Johannes, Cooper, Matthew A., Lewis, Peter J. and McCluskey, Adam (2022). Amino alcohols as potential antibiotic and antifungal leads. Molecules, 27 (7) 2050, 2050. doi: 10.3390/molecules27072050

Amino alcohols as potential antibiotic and antifungal leads

2022

Journal Article

Nanomaterials: the new antimicrobial magic bullet

Ndayishimiye, John, Kumeria, Tushar, Popat, Amirali, Falconer, James Robert and Blaskovich, Mark A. T. (2022). Nanomaterials: the new antimicrobial magic bullet. ACS Infectious Diseases, 8 (4), 693-712. doi: 10.1021/acsinfecdis.1c00660

Nanomaterials: the new antimicrobial magic bullet

2022

Journal Article

Understanding the relationship between solubility and permeability of γ-cyclodextrin-based systems embedded with poorly aqueous soluble benznidazole

Ndayishimiye, John, Kumeria, Tushar, Popat, Amirali, Blaskovich, Mark A.T. and Falconer, James Robert (2022). Understanding the relationship between solubility and permeability of γ-cyclodextrin-based systems embedded with poorly aqueous soluble benznidazole. International Journal of Pharmaceutics, 616 121487, 121487. doi: 10.1016/j.ijpharm.2022.121487

Understanding the relationship between solubility and permeability of γ-cyclodextrin-based systems embedded with poorly aqueous soluble benznidazole

2022

Other Outputs

Peptide Antibiotics

Matthew Cooper, Mark Blaskovich, Alejandra Gallardo-Godoy, Karl Hansford, Alysha Elliott, Carig Muldoon and Bernd Becker (2022). Peptide Antibiotics. US11279733.

Peptide Antibiotics

2022

Journal Article

Antimicrobial activity enhancers: towards smart delivery of antimicrobial agents

Skwarczynski, Mariusz, Bashiri, Sahra, Yuan, Ye, Ziora, Zyta M., Nabil, Osama, Masuda, Keita, Khongkow, Mattaka, Rimsueb, Natchanon, Cabral, Horacio, Ruktanonchai, Uracha, Blaskovich, Mark A. T. and Toth, Istvan (2022). Antimicrobial activity enhancers: towards smart delivery of antimicrobial agents. Antibiotics, 11 (3) 412, 412. doi: 10.3390/antibiotics11030412

Antimicrobial activity enhancers: towards smart delivery of antimicrobial agents

2022

Journal Article

Booster for antibiotics

Blaskovich, Mark (2022). Booster for antibiotics. Chemistry and Industry, 86 (3), 30-33. doi: 10.1002/cind.863_9.x

Booster for antibiotics

2022

Journal Article

Featured article editorial: discovery of a tricyclic β-lactam active against carbapenem-resistant enterobacterales

Blaskovich, Mark (2022). Featured article editorial: discovery of a tricyclic β-lactam active against carbapenem-resistant enterobacterales. ACS Infectious Diseases, 8 (3) acsinfecdis.2c00088, 398-398. doi: 10.1021/acsinfecdis.2c00088

Featured article editorial: discovery of a tricyclic β-lactam active against carbapenem-resistant enterobacterales

2022

Journal Article

Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection

De Oliveira, David M. P., Forde, Brian M., Phan, Minh-Duy, Steiner, Bernhard, Zhang, Bing, Zuegg, Johannes, El-deeb, Ibrahim M., Li, Gen, Keller, Nadia, Brouwer, Stephan, Harbison-Price, Nichaela, Cork, Amanda J., Bauer, Michelle J., Alquethamy, Saleh F., Beatson, Scott A., Roberts, Jason A., Paterson, David L., McEwan, Alastair G., Blaskovich, Mark A. T., Schembri, Mark A., McDevitt, Christopher A., von Itzstein, Mark and Walker, Mark J. (2022). Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection. mBio, 13 (1) e03517, e0351721. doi: 10.1128/mbio.03517-21

Rescuing Tetracycline Class Antibiotics for the Treatment of Multidrug-Resistant Acinetobacter baumannii Pulmonary Infection

2022

Book Chapter

Application of antibiotic-derived fluorescent probes to bacterial studies

Zhang, Bing, Stone, M. Rhia L., Kc, Sanjaya, Łapińska, Urszula, Pagliara, Stefano and Blaskovich, Mark A.T. (2022). Application of antibiotic-derived fluorescent probes to bacterial studies. Methods in enzymology. (pp. 1-28) edited by Erin E. Carlson. San Diego, CA United States: Academic Press. doi: 10.1016/bs.mie.2021.11.010

Application of antibiotic-derived fluorescent probes to bacterial studies

2021

Journal Article

Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth

Goodall, Emily C. A., Isom, Georgia L., Rooke, Jessica L., Pullela, Karthik, Icke, Christopher, Yang, Zihao, Boelter, Gabriela, Jones, Alun, Warner, Isabel, Da Costa, Rochelle, Zhang, Bing, Rae, James, Tan, Wee Boon, Winkle, Matthias, Delhaye, Antoine, Heinz, Eva, Collet, Jean-Francois, Cunningham, Adam F., Blaskovich, Mark A., Parton, Robert G., Cole, Jeff A., Banzhaf, Manuel, Chng, Shu-Sin, Vollmer, Waldemar, Bryant, Jack A. and Henderson, Ian R. (2021). Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth. PLoS Genetics, 17 (12) e1009586, 1-40. doi: 10.1371/journal.pgen.1009586

Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth