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2020

Journal Article

How to stimulate and facilitate early stage antibiotic discovery

Zuegg, Johannes, Hansford, Karl A., Elliott, Alysha G., Cooper, Matthew A. and Blaskovich, Mark A. T. (2020). How to stimulate and facilitate early stage antibiotic discovery. ACS Infectious Diseases, 6 (6), 1302-1304. doi: 10.1021/acsinfecdis.0c00163

How to stimulate and facilitate early stage antibiotic discovery

2020

Journal Article

Metal complexes as a promising source for new antibiotics

Frei, Angelo, Zuegg, Johannes, Elliott, Alysha G., Baker, Murray V., Braese, Stefan, Brown, Christopher, Chen, Feng, Dowson, Christopher Gerard, Dujardin, Gilles, Jung, Nicole, King, A. Paden, Mansour, Ahmed Moustafa, Massi, Massimiliano, Moat, John, Mohamed, Heba A., Renfrew, Anna, Rutledge, Peter, Sadler, Peter J., Todd, Matthew Houghton, Willans, Charlotte E., Wilson, Justin Jeff, Cooper, Matthew Allister and Blaskovich, Mark (2020). Metal complexes as a promising source for new antibiotics. Chemical Science, 11 (10), 2627-2639. doi: 10.1039/c9sc06460e

Metal complexes as a promising source for new antibiotics

2019

Journal Article

The diminished antimicrobial pipeline

Blaskovich, Mark A.T. (2019). The diminished antimicrobial pipeline. Microbiology Australia, 40 (2), 92-96. doi: 10.1071/MA19025

The diminished antimicrobial pipeline

2019

Journal Article

Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux

Stone, M. Rhia L., Masi, Muriel, Phetsang, Wanida, Pagès, Jean-Marie, Cooper, Matthew A. and Blaskovich, Mark A. T. (2019). Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux. MedChemComm, 10 (6), 901-906. doi: 10.1039/c9md00124g

Fluoroquinolone-derived fluorescent probes for studies of bacterial penetration and efflux

2018

Journal Article

Can octapeptin antibiotics combat extensively drug-resistant (XDR) bacteria?

Blaskovich, Mark A. T., Pitt, Miranda E., Elliott, Alysha G. and Cooper, Matthew A. (2018). Can octapeptin antibiotics combat extensively drug-resistant (XDR) bacteria?. Expert Review of Anti-infective Therapy, 16 (6), 485-499. doi: 10.1080/14787210.2018.1483240

Can octapeptin antibiotics combat extensively drug-resistant (XDR) bacteria?

2018

Journal Article

Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance

Stone, M Rhia L., Butler, Mark S., Phetsang, Wanida, Cooper, Matthew A. and Blaskovich, Mark A. T. (2018). Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance. Trends in Biotechnology, 36 (5), 523-536. doi: 10.1016/j.tibtech.2018.01.004

Fluorescent Antibiotics: New Research Tools to Fight Antibiotic Resistance

2018

Journal Article

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria

Velkov, Tony, Gallardo-Godoy, Alejandra, Swarbrick, James D., Blaskovich, Mark A. T., Elliott, Alysha G., Han, Meiling, Thompson, Philip E., Roberts, Kade D., Huang, Johnny X., Becker, Bernd, Butler, Mark S., Lash, Lawrence H., Henriques, Sónia Troeira, Nation, Roger L., Sivanesan, Sivashangarie, Sani, Marc-Antoine, Separovic, Frances, Mertens, Haydyn, Bulach, Dieter, Seemann, Torsten, Owen, Jeremy, Li, Jian and Cooper, Matthew A. (2018). Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria. Cell Chemical Biology, 25 (4), 380-391.e5. doi: 10.1016/j.chembiol.2018.01.005

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria

2018

Journal Article

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria

Blaskovich, Mark A T, Hansford, Karl A., Gong, Yujing, Butler, Mark S., Muldoon, Craig, Huang, Johnny X., Ramu, Soumya, Silva, Alberto B., Cheng, Mu, Kavanagh, Angela M., Ziora, Zyta, Premraj, Rajaratnam, Lindahl, Fredrik, Bradford, Tanya A., Lee, June C., Karoli, Tomislav, Pelingon, Ruby, Edwards, David J., Amado, Maite, Elliott, Alysha G, Phetsang, Wanida, Daud, Noor Huda, Deecke, Johan E, Sidjabat, Hanna E, Ramaologa, Sefetogi, Zuegg, Johannes, Betley, Jason R, Beevers, Andrew P G, Smith, Richard A G ... Cooper, Matthew A. (2018). Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria. Nature Communications, 9 (1) 02123, 22. doi: 10.1038/s41467-017-02123-w

Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria

2016

Journal Article

Unusual amino acids in medicinal chemistry

Blaskovich, Mark A. T. (2016). Unusual amino acids in medicinal chemistry. Journal of Medicinal Chemistry, 59 (24), 10807-10836. doi: 10.1021/acs.jmedchem.6b00319

Unusual amino acids in medicinal chemistry

2016

Journal Article

Antibiotics in the clinical pipeline at the end of 2015

Butler, Mark S., Blaskovich, Mark A. T. and Cooper, Matthew A. (2016). Antibiotics in the clinical pipeline at the end of 2015. The Journal of Antibiotics, 70 (1), 1-22. doi: 10.1038/ja.2016.72

Antibiotics in the clinical pipeline at the end of 2015

2016

Journal Article

Fluorescent trimethoprim conjugate probes to assess drug accumulation in wild type and mutant Escherichia coli

Phetsang, Wanida, Pelingon, Ruby, Butler, Mark S., KC, Sanjaya, Pitt, Miranda, Kaeslin, Geraldine, Cooper, Matthew A. and Blaskovich, Mark A. T. (2016). Fluorescent trimethoprim conjugate probes to assess drug accumulation in wild type and mutant Escherichia coli. ACS Infectious Diseases, 2 (10), 688-701. doi: 10.1021/acsinfecdis.6b00080

Fluorescent trimethoprim conjugate probes to assess drug accumulation in wild type and mutant Escherichia coli

2010

Book

Handbook on syntheses of amino acids : General routes for the syntheses of amino acids

Blaskovich, Mark A (2010). Handbook on syntheses of amino acids : General routes for the syntheses of amino acids. First ed. New York , NY, U.S.A.: Oxford University Press; American Chemical Society.

Handbook on syntheses of amino acids : General routes for the syntheses of amino acids

2026

Journal Article

High prevalence and co-existence of SHV and CTX-M genes in extensively drug-resistant (XDR) Gram-negative bacteria isolated from hospital settings in Faisalabad District, Pakistan

Abbas, Umair, Sajjad, Huma, Shaukat, Amir, Ahmad, Zaheer, Sattar, Azfar, Shehzad, Khurram, Blaskovich, Mark A. T., Da Silva Duarte, Tania, Zuegg, Johannes, Ali, Aamir and Sarwar, Yasra (2026). High prevalence and co-existence of SHV and CTX-M genes in extensively drug-resistant (XDR) Gram-negative bacteria isolated from hospital settings in Faisalabad District, Pakistan. Molecular Biology Reports, 53 (1) 494, 1-11. doi: 10.1007/s11033-026-11654-9

High prevalence and co-existence of SHV and CTX-M genes in extensively drug-resistant (XDR) Gram-negative bacteria isolated from hospital settings in Faisalabad District, Pakistan

2026

Journal Article

High-throughput screening assays for novel antibacterial identification: current advances and future prospects

Floyd, Holly E. E., Novais de Paula, Michelle, Sen, Tanuka, Kavanagh, Angela M., Zuegg, Johannes and Blaskovich, Mark A. T. (2026). High-throughput screening assays for novel antibacterial identification: current advances and future prospects. Expert Opinion on Drug Discovery, 1-15. doi: 10.1080/17460441.2026.2679706

High-throughput screening assays for novel antibacterial identification: current advances and future prospects

2026

Journal Article

Pyrazolyl–Pyridine Ruthenium Complexes: A New Metallic Line of Defense Against Acinetobacter baumannii

Joseph, M. Cassiem, Sookai, Sheldon, Nowakowska, Monika, Mphephu, Rotondwa, Kavanagh, Angela M., Zuegg, Johannes, Blaskovich, Mark A. T. and Swarts, Andrew J. (2026). Pyrazolyl–Pyridine Ruthenium Complexes: A New Metallic Line of Defense Against Acinetobacter baumannii. ChemBioChem, 27 (9) e70371. doi: 10.1002/cbic.70371

Pyrazolyl–Pyridine Ruthenium Complexes: A New Metallic Line of Defense Against Acinetobacter baumannii

2026

Journal Article

Framework for evaluating explainable AI in antimicrobial drug discovery

Onawole, Abdulmujeeb T., Blaskovich, Mark A. T. and Zuegg, Johannes (2026). Framework for evaluating explainable AI in antimicrobial drug discovery. Journal of Cheminformatics. doi: 10.1186/s13321-026-01200-x

Framework for evaluating explainable AI in antimicrobial drug discovery

2026

Journal Article

<i>In vitro</i> activity of robenidine analogue NCL195 against methicillin-resistant <i>Staphylococcus pseudintermedius</i>

Bista, Sayara, Nguyen, Hang Thi, Soares da Costa, Tatiana P., Woolford, Lucy, Blaskovich, Mark A. T., Veltman, Tania, Young, Kelly A., McCluskey, Adam, Siak, Meng, Page, Stephen W., Venter, Henrietta, Trott, Darren J. and Ogunniyi, Abiodun D. (2026). In vitro activity of robenidine analogue NCL195 against methicillin-resistant Staphylococcus pseudintermedius. Microbiology Spectrum e03187-25. doi: 10.1128/spectrum.03187-25

<i>In vitro</i> activity of robenidine analogue NCL195 against methicillin-resistant <i>Staphylococcus pseudintermedius</i>

2026

Journal Article

Synthesis and biological evaluation of the complete octapeptin natural product series

Bolisetti, Raghu, Hansford, Karl A., Zuegg, Johannes, Elliott, Alysha G., Friberg, Louise I. M., Cooper, Matthew A. and Blaskovich, Mark A. T. (2026). Synthesis and biological evaluation of the complete octapeptin natural product series. Journal of Medicinal Chemistry, 69 (3), 2439-2452. doi: 10.1021/acs.jmedchem.5c02335

Synthesis and biological evaluation of the complete octapeptin natural product series

2026

Journal Article

Rapid profiling of polymyxin B susceptibility in gram-negative bacteria with a novel polymyxin-derived fluorescent probe

Zhang, Bing, Phetsang, Wanida, Kc, Sanjaya, Butler, Mark S., Pelingon, Ruby, Elliott, Alysha G., Amado, Maite, Gallardo-Godoy, Alejandra, Cooper, Matthew A. and Blaskovich, Mark A. T. (2026). Rapid profiling of polymyxin B susceptibility in gram-negative bacteria with a novel polymyxin-derived fluorescent probe. Journal of Advanced Research. doi: 10.1016/j.jare.2026.01.019

Rapid profiling of polymyxin B susceptibility in gram-negative bacteria with a novel polymyxin-derived fluorescent probe

2025

Journal Article

Organoselenium compounds as a promising source of novel antimicrobial agents

Friberg, Louise I. M., Blanchfield, Joanne T. and Blaskovich, Mark. A. T. (2025). Organoselenium compounds as a promising source of novel antimicrobial agents. Journal of Medicinal Chemistry, 68 (24), 25729-25753. doi: 10.1021/acs.jmedchem.5c02460

Organoselenium compounds as a promising source of novel antimicrobial agents