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2025

Journal Article

Recent developments in cyclin-dependent kinase (CDK) PROTAC in cancer therapy

Nandi, Arijit, Das, Anwesha, Stone, M. Rhia L. and Blaskovich, Mark A. T. (2025). Recent developments in cyclin-dependent kinase (CDK) PROTAC in cancer therapy. ACS Medicinal Chemistry Letters, 16 (12), 2373-2384. doi: 10.1021/acsmedchemlett.5c00462

Recent developments in cyclin-dependent kinase (CDK) PROTAC in cancer therapy

2025

Journal Article

Hyperforin potentiates polymyxin B against multidrug-resistant Gram-negative pathogens via membrane disruption, biofilm eradication, and oxidative stress

Hussein, Maytham, Crawford, Simon, Baker, Mark, Floyd, Holly, Allobawi, Rafah, Blaskovich, Mark A. T., Rao, Gauri G., Zuegg, Johannes, Li, Jian and Velkov, Tony (2025). Hyperforin potentiates polymyxin B against multidrug-resistant Gram-negative pathogens via membrane disruption, biofilm eradication, and oxidative stress. Antimicrobial Agents and Chemotherapy, 69 (12) e01007-25, 1-15. doi: 10.1128/aac.01007-25

Hyperforin potentiates polymyxin B against multidrug-resistant Gram-negative pathogens via membrane disruption, biofilm eradication, and oxidative stress

2025

Conference Publication

Seeing the unseen: imaging bacterial infections

Stone, Magali, Ramu, Soumya, Bhalla, Rajiv, Mardon, Karine and Blaskovich, Mark (2025). Seeing the unseen: imaging bacterial infections. International Symposium on Radiopharmaceutical Sciences iSRS 2025, Gold Coast, QLD, Australia, 11-15 May 2025. Philadelphia, PA, United States: Elsevier. doi: 10.1016/j.nucmedbio.2025.109403

Seeing the unseen: imaging bacterial infections

2025

Journal Article

A comparative review of the pharmacology of dalbavancin and oritavancin for gram-positive infections: Birds of a feather or apples and oranges?

Hussein, Maytham, Barclay, James, Baker, Mark, Wu, Yuezhou, Thombare, Varsha J., Patil, Nitin, Murthy, Ananya B., Sharma, Rajnikant, Rao, Gauri G., Blaskovich, Mark A. T., Li, Jian and Velkov, Tony (2025). A comparative review of the pharmacology of dalbavancin and oritavancin for gram-positive infections: Birds of a feather or apples and oranges?. Infectious Diseases and Therapy, 14 (10), 2221-2246. doi: 10.1007/s40121-025-01215-1

A comparative review of the pharmacology of dalbavancin and oritavancin for gram-positive infections: Birds of a feather or apples and oranges?

2025

Journal Article

Loss of cardiolipin and porins bypasses the essentiality of the sigma E cell envelope stress response in Escherichia coli

Yang, Zihao, Goodall, Emily C. A., Zhang, Bing, Torres, Von V. L., Rooke, Jessica L., Pullela, Karthik, Da Costa, Rochelle M., Icke, Christopher, Blaskovich, Mark A.T., Legood, Simon, Cunningham, Adam F., Vollmer, Waldemar, Bryant, Jack A. and Henderson, Ian R. (2025). Loss of cardiolipin and porins bypasses the essentiality of the sigma E cell envelope stress response in Escherichia coli. mBio, 16 (9) e01613-25, e0161325. doi: 10.1128/mbio.01613-25

Loss of cardiolipin and porins bypasses the essentiality of the sigma E cell envelope stress response in Escherichia coli

2025

Journal Article

RhoA and Rac1 as mechanotransduction mediators in colorectal cancer

Yadav, Sharda, K. C., Sanjaya, Blaskovich, Mark A. T., Lu, Cu‐tai, Lam, Alfred K and Nguyen, Nam‐Trung (2025). RhoA and Rac1 as mechanotransduction mediators in colorectal cancer. Advanced Biology, 9 (8) 2400626, 1-13. doi: 10.1002/adbi.202400626

RhoA and Rac1 as mechanotransduction mediators in colorectal cancer

2025

Journal Article

Heterogeneous efflux pump expression underpins phenotypic resistance to antimicrobial peptides

Lee, Ka Kiu, Łapińska, Urszula, Tolle, Giulia, Micaletto, Maureen, Zhang, Bing, Phetsang, Wanida, Verderosa, Anthony D., Invergo, Brandon M., Westley, Joseph, Bebes, Attila, Yuecel, Raif, O'Neill, Paul A., Farbos, Audrey, Jeffries, Aaron R., van Houte, Stineke, Caboni, Pierluigi, Blaskovich, Mark A. T., Housden, Benjamin E., Tsaneva-Atanasova, Krasimira and Pagliara, Stefano (2025). Heterogeneous efflux pump expression underpins phenotypic resistance to antimicrobial peptides. eLife, 13. doi: 10.7554/elife.99752.4

Heterogeneous efflux pump expression underpins phenotypic resistance to antimicrobial peptides

2025

Journal Article

Nanoparticle based antigen detection of norovirus in human faecal samples: A proof-of-concept study

Pandey, Rishi, Gyawali, Pradip, Blaskovich, Mark A.T. and Sanjaya, K.C. (2025). Nanoparticle based antigen detection of norovirus in human faecal samples: A proof-of-concept study. Environmental Nanotechnology, Monitoring & Management, 23 101064, 1-7. doi: 10.1016/j.enmm.2025.101064

Nanoparticle based antigen detection of norovirus in human faecal samples: A proof-of-concept study

2025

Journal Article

Antibiotics re-booted—time to kick back against drug resistance

Blaskovich, Mark A. T. and Cooper, Matthew A. (2025). Antibiotics re-booted—time to kick back against drug resistance. npj Antimicrobials and Resistance, 3 (1) 47, 1-20. doi: 10.1038/s44259-025-00096-1

Antibiotics re-booted—time to kick back against drug resistance

2025

Journal Article

Characterisation of in vitro resistance selection against second-/last-line antibiotics in methicillin-resistant Staphylococcus aureus ATCC 43300 strain

Prasetyoputri, Anggia, Pitt, Miranda E., Cao, Minh Duc, Ramu, Soumya, Kavanagh, Angela, Elliott, Alysha G., Ganesamoorthy, Devika, Monk, Ian R., Stinear, Timothy P., Cooper, Matthew A., Coin, Lachlan J. M. and Blaskovich, Mark A. T. (2025). Characterisation of in vitro resistance selection against second-/last-line antibiotics in methicillin-resistant Staphylococcus aureus ATCC 43300 strain. JAC - Antimicrobial Resistance, 7 (3) dlaf108, dlaf108. doi: 10.1093/jacamr/dlaf108

Characterisation of in vitro resistance selection against second-/last-line antibiotics in methicillin-resistant Staphylococcus aureus ATCC 43300 strain

2025

Journal Article

Organoselenium compounds as an enriched source for the discovery of new antimicrobial agents

Friberg, Louise I. M., Kavanagh, Angela, Amado, Maite, Lowe, Gabrielle, Zuegg, Johannes, Novais de Paula, Michelle, Onawole, Abdulmujeeb, Floyd, Holly, Kravchenko, Angelina Nikolaevna, Guan, Davy, Elliott, Alysha, Kuchar, Julia, Mohr, Fabian, Luzina, Olga, Salakhutdinov, Nariman F., Volcho, Konstantin, Farrukh, Hafiz S. U. B., Kalsoom, Umme, Saleem, Rahman Shah Zaib, Blanchfield, Joanne Therese, Blaskovich, Mark A. T. and Hansford, Karl (2025). Organoselenium compounds as an enriched source for the discovery of new antimicrobial agents. RSC Medicinal Chemistry, 16 (7), 3213-3228. doi: 10.1039/d4md00677a

Organoselenium compounds as an enriched source for the discovery of new antimicrobial agents

2025

Journal Article

Natural product-derived compounds in clinical trials and drug approvals

Butler, Mark S., Capon, Robert J., Blaskovich, Mark A. T. and Henderson, Ian R. (2025). Natural product-derived compounds in clinical trials and drug approvals. Natural Product Reports, 43 (1), 20-88. doi: 10.1039/d5np00031a

Natural product-derived compounds in clinical trials and drug approvals

2025

Journal Article

Antibiofilm efficacy of a green graphene oxide-silver nanocomposite against mixed microbial species biofilms: an in-vitro and in-silico approach

Khan, Sadaf, Almuqrin, Amjad, Seneviratne, Jaya, Pant, Kamal Kishore, Ziora, Zyta and Blaskovich, Mark A.T. (2025). Antibiofilm efficacy of a green graphene oxide-silver nanocomposite against mixed microbial species biofilms: an in-vitro and in-silico approach. RSC Sustainability, 3 (11), 5249-5259. doi: 10.1039/d5su00093a

Antibiofilm efficacy of a green graphene oxide-silver nanocomposite against mixed microbial species biofilms: an in-vitro and in-silico approach

2024

Journal Article

Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans

Floyd, Holly E. E., Kavanagh, Angela M., Lowe, Gabrielle J., Amado, Maite, Fraser, James A., Blaskovich, Mark A. T., Elliott, Alysha G. and Zuegg, Johannes (2024). Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans. Scientific Reports, 14 (1) 23407, 23407. doi: 10.1038/s41598-024-74068-2

Standardisation of high throughput microdilution antifungal susceptibility testing for Candida albicans and Cryptococcus neoformans

2024

Journal Article

Tetrazoles: A multi-potent motif in drug design

Yuan, Ye, Li, Muzi, Apostolopoulos, Vasso, Matsoukas, John, Wolf, Wojciech M., Blaskovich, Mark A.T., Bojarska, Joanna and Ziora, Zyta M. (2024). Tetrazoles: A multi-potent motif in drug design. European Journal of Medicinal Chemistry, 279 116870, 1-18. doi: 10.1016/j.ejmech.2024.116870

Tetrazoles: A multi-potent motif in drug design

2024

Book Chapter

Treatment of Urban Wastewater with a View towards Recycling and Reuse in India

Jain, Marut, Chauhan, Ruchi, Mishra, Deepti, Sahoo, Abhisek, Kishore Pant, Kamal, Ziora, Zyta Maria and Blaskovich, Mark A.T. (2024). Treatment of Urban Wastewater with a View towards Recycling and Reuse in India. Innovative and Hybrid Technologies for Wastewater Treatment and Recycling. (pp. 13-36) Boca Raton, FL United States: CRC Press. doi: 10.1201/9781003454199-2

Treatment of Urban Wastewater with a View towards Recycling and Reuse in India

2024

Journal Article

Adjuvant strategies to tackle mcr-mediated polymyxin resistance

Nuske, Madison R., Zhong, Junlang, Huang, Renjie, Sarojini, Vijayalekshmi, Chen, Jack L. Y., Squire, Christopher J., Blaskovich, Mark A. T. and Leung, Ivanhoe K. H. (2024). Adjuvant strategies to tackle mcr-mediated polymyxin resistance. RSC Medicinal Chemistry, 16 (2), 465-480. doi: 10.1039/d4md00654b

Adjuvant strategies to tackle mcr-mediated polymyxin resistance

2024

Journal Article

A review of antibacterial candidates with new modes of action

Butler, Mark S., Vollmer, Waldemar, Goodall, Emily C. A., Capon, Robert J., Henderson, Ian R. and Blaskovich, Mark A. T. (2024). A review of antibacterial candidates with new modes of action. ACS Infectious Diseases, 10 (10), 3440-3474. doi: 10.1021/acsinfecdis.4c00218

A review of antibacterial candidates with new modes of action

2024

Journal Article

Phage-induced efflux down-regulation boosts antibiotic efficacy

Kraus, Samuel, Fletcher, Megan L., Łapińska, Urszula, Chawla, Krina, Baker, Evan, Attrill, Erin L., O’Neill, Paul, Farbos, Audrey, Jeffries, Aaron, Galyov, Edouard E., Korbsrisate, Sunee, Barnes, Kay B., Harding, Sarah V., Tsaneva-Atanasova, Krasimira, Blaskovich, Mark A.T. and Pagliara, Stefano (2024). Phage-induced efflux down-regulation boosts antibiotic efficacy. PLoS Pathogens, 20 (6 June) e1012361, 1-33. doi: 10.1371/journal.ppat.1012361

Phage-induced efflux down-regulation boosts antibiotic efficacy

2024

Journal Article

Modelling and statistical interpretation of phenol adsorption behaviour of 3-Dimensional hybrid aerogel of waste-derived carbon nanotubes and graphene oxide

Jain, Marut, Sahoo, Abhisek, Mishra, Deepti, Aiman Khan, Sadaf, Kishore Pant, Kamal, Ziora, Zyta M. and Blaskovich, Mark A.T. (2024). Modelling and statistical interpretation of phenol adsorption behaviour of 3-Dimensional hybrid aerogel of waste-derived carbon nanotubes and graphene oxide. Chemical Engineering Journal, 490 151351, 1-17. doi: 10.1016/j.cej.2024.151351

Modelling and statistical interpretation of phenol adsorption behaviour of 3-Dimensional hybrid aerogel of waste-derived carbon nanotubes and graphene oxide