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2016

Journal Article

Identification and outcomes of clinical phenotypes in amyotrophic lateral sclerosis/motor neuron disease: Australian National Motor Neuron Disease observational cohort

Talman, Paul, Thi Duong, Vucic, Steve, Mathers, Susan, Venkatesh, Svetha, Henderson, Robert, Rowe, Dominic, Schultz, David, Edis, Robert, Needham, Merrilee, Macdonnell, Richard, McCombe, Pamela, Birks, Carol and Kiernan, Matthew (2016). Identification and outcomes of clinical phenotypes in amyotrophic lateral sclerosis/motor neuron disease: Australian National Motor Neuron Disease observational cohort. BMJ Open, 6 (9) e012054, e012054. doi: 10.1136/bmjopen-2016-012054

Identification and outcomes of clinical phenotypes in amyotrophic lateral sclerosis/motor neuron disease: Australian National Motor Neuron Disease observational cohort

2016

Journal Article

Defining secondary progressive multiple sclerosis

Lorscheider, Johannes, Buzzard, Katherine, Jokubaitis, Vilija, Spelman, Tim, Havrdova, Eva, Horakova, Dana, Trojano, Maria, Izquierdo, Guillermo, Girard, Marc, Duquette, Pierre, Prat, Alexandre, Lugaresi, Alessandra, Grand'maison, Francois, Grammond, Pierre, Hupperts, Raymond, Alroughani, Raed, Sola, Patrizia, Boz, Cavit, Pucci, Eugenio, Lechner-Scott, Jeanette, Bergamaschi, Roberto, Oreja-Guevara, Celia, Iuliano, Gerardo, Van Pesch, Vincent, Granella, Franco, Ramo-Tello, Cristina, Spitaleri, Daniele, Petersen, Thor, Slee, Mark ... Kalincik, Tomas (2016). Defining secondary progressive multiple sclerosis. Brain, 139 (9), 2395-2405. doi: 10.1093/brain/aww173

Defining secondary progressive multiple sclerosis

2016

Journal Article

Altered metabolic homeostasis in amyotrophic lateral sclerosis: mechanisms of energy imbalance and contribution to disease progression

Ioannides, Z. A., Ngo, S. T., Henderson, R. D., McCombe, P. A. and Steyn, F. J. (2016). Altered metabolic homeostasis in amyotrophic lateral sclerosis: mechanisms of energy imbalance and contribution to disease progression. Neurodegenerative Diseases, 15 (5-6), 382-397. doi: 10.1159/000446502

Altered metabolic homeostasis in amyotrophic lateral sclerosis: mechanisms of energy imbalance and contribution to disease progression

2016

Journal Article

Predictors of long-term disability accrual in relapse-onset multiple sclerosis

Jokubaitis, Vilija G., Spelman, Tim, Kalincik, Tomas, Lorscheider, Johannes, Havrdova, Eva, Horakova, Dana, Duquette, Pierre, Girard, Marc, Prat, Alexandre, Izquierdo, Guillermo, Grammond, Pierre, Van Pesch, Vincent, Pucci, Eugenio, Grand'Maison, Francois, Hupperts, Raymond, Granella, Franco, Sola, Patrizia, Bergamaschi, Roberto, Iuliano, Gerardo, Spitaleri, Daniele, Boz, Cavit, Hodgkinson, Suzanne, Olascoaga, Javier, Verheul, Freek, McCombe, Pamela, Petersen, Thor, Rozsa, Csilla, Lechner-Scott, Jeannette, Laura Saladino, Maria ... Trojano, Maria (2016). Predictors of long-term disability accrual in relapse-onset multiple sclerosis. Annals of Neurology, 80 (1), 89-100. doi: 10.1002/ana.24682

Predictors of long-term disability accrual in relapse-onset multiple sclerosis

2016

Journal Article

Interleukin 6 promoter 174 G/C polymorphisms in acute ischemic stroke: G allele is protective but not associated with IL-6 levels or stroke outcome

Yan, J., Greer, J. M. and McCombe, P. A. (2016). Interleukin 6 promoter 174 G/C polymorphisms in acute ischemic stroke: G allele is protective but not associated with IL-6 levels or stroke outcome. Journal of Neuroimmunology, 293, 22-27. doi: 10.1016/j.jneuroim.2016.02.001

Interleukin 6 promoter 174 G/C polymorphisms in acute ischemic stroke: G allele is protective but not associated with IL-6 levels or stroke outcome

2016

Journal Article

Contribution of different relapse phenotypes to disability in multiple sclerosis

Stewart, Tamasine, Spelman, Tim, Havrdova, Eva, Horakova, Dana, Trojano, Maria, Izquierdo, Guillermo, Duquette, Pierre, Girard, Marc, Prat, Alexandre, Lugaresi, Alessandra, Grand'Maison, Francois, Grammond, Pierre, Sola, Patrizia, Shaygannejad, Vahid, Hupperts, Raymond, Alroughani, Raed, Oreja-Guevara, Celia, Pucci, Eugenio, Boz, Cavit, Lechner-Scott, Jeannette, Bergamaschi, Roberto, Van Pesch, Vincent, Iuliano, Gerardo, Ramo, Cristina, Taylor, Bruce, Slee, Mark, Spitaleri, Daniele, Granella, Franco, Verheul, Freek ... Kalincik, Tomas (2016). Contribution of different relapse phenotypes to disability in multiple sclerosis. Multiple Sclerosis Journal, 23 (2), 266-276. doi: 10.1177/1352458516643392

Contribution of different relapse phenotypes to disability in multiple sclerosis

2016

Conference Publication

Pregnancy Outcomes in Patients with RRMS Who Received Alemtuzumab in the Clinical Development Program

Oh, Jiwon, Achiron, Anat, Chambers, Christina, Fox, Edward, McCombe, Pamela, Otero, Susana, Margolin, David, Kasten, Linda and Compston, D. Alastair (2016). Pregnancy Outcomes in Patients with RRMS Who Received Alemtuzumab in the Clinical Development Program. AAN 68th Annual Meeting, Vancouver, Canada, 15 - 21 April 2016. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1212/wnl.86.16_supplement.s24.008

Pregnancy Outcomes in Patients with RRMS Who Received Alemtuzumab in the Clinical Development Program

2016

Conference Publication

Prospectively tracking disease course and treatment changes in Neuromyelitis Optica using NMOBase, a global online registry

Kister, Ilya, Bacon, Tamar, Shaygannejad, Vahid, Hor, Jyh Yung, Alroughani, Raed, Haas, Shannon, Terzi, Murat, Boz, Cavit, Olascoaga, Javier, McCombe, Pamela, Fragoso, Yara, Lugaresi, Alessandra, Sola, Patrizia, Vucic, Steve, Pucci, Eugenio, Al-Harbi, Talal, Sajedi, Seyed Aidin, Rojas, Juan Ignacio, Patrucco, Liliana, Cristiano, Edgardo, Suarez, Jose Alberto, Tsolaki, Magdalini, Taylor, Bruce, Iuliano, Gerardo, Devranis, Paschalis, Marriott, Mark and Butzkueven, Helmut (2016). Prospectively tracking disease course and treatment changes in Neuromyelitis Optica using NMOBase, a global online registry. AAN 68th Annual Meeting, Vancouver, Canada, 15 - 21 April 2016. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1212/wnl.86.16_supplement.p5.307

Prospectively tracking disease course and treatment changes in Neuromyelitis Optica using NMOBase, a global online registry

2016

Journal Article

A case series of patients with autoimmune myasthenia gravis in association with invasive thymoma

McCombe, Pamela, Raj, Meenakshi, Henderson, Robert and Blum, Stefan (2016). A case series of patients with autoimmune myasthenia gravis in association with invasive thymoma. Journal of Clinical Neuromuscular Disease, 17 (3), 129-134. doi: 10.1097/CND.0000000000000101

A case series of patients with autoimmune myasthenia gravis in association with invasive thymoma

2016

Conference Publication

Durable Effect of Alemtuzumab on Clinical Outcomes Over 5 years in Treatment-Naive Patients With Active Relapsing-Remitting Multiple Sclerosis Despite Most Patients Not Receiving Treatment for 4 Years: CARE-MS I Extension Study

McCombe, P. A., Hartung, H-P, Havrdova, E., Selmaj, K. W., Margolin, D. H., Kasten, L. and Compston, D. A. S. (2016). Durable Effect of Alemtuzumab on Clinical Outcomes Over 5 years in Treatment-Naive Patients With Active Relapsing-Remitting Multiple Sclerosis Despite Most Patients Not Receiving Treatment for 4 Years: CARE-MS I Extension Study. 8th Congress of the Pan-Asian-Committee-for-Research-and-Treatment-of-Multiple-Sclerosis (PACTRIMS), Seoul South Korea, Nov 19-21, 2015. LONDON: SAGE PUBLICATIONS LTD.

Durable Effect of Alemtuzumab on Clinical Outcomes Over 5 years in Treatment-Naive Patients With Active Relapsing-Remitting Multiple Sclerosis Despite Most Patients Not Receiving Treatment for 4 Years: CARE-MS I Extension Study

2016

Conference Publication

Pregnancy Outcomes in Alemtuzumab-Treated Female Patients with Active RRMS in the Clinical Development Program.

McCombe, P., Achiron, A., Chambers, C., Fox, E. J., Otero, S., Margolin, D. H., Kasten, L. and Compston, D. A. S. (2016). Pregnancy Outcomes in Alemtuzumab-Treated Female Patients with Active RRMS in the Clinical Development Program.. 8th Congress of the Pan-Asian-Committee-for-Research-and-Treatment-of-Multiple-Sclerosis (PACTRIMS), Seoul South Korea, Nov 19-21, 2015. LONDON: SAGE PUBLICATIONS LTD.

Pregnancy Outcomes in Alemtuzumab-Treated Female Patients with Active RRMS in the Clinical Development Program.

2016

Conference Publication

Durable improvement in clinical outcomes in treatmentnaive patients with relapsing-remitting multiple sclerosis who switched from SC IFNB-1a to alemtuzumab (care-MS I extension study 4-year follow-up)

Oreja-Guevara, C., Alroughani, R., Brassat, D., Boyko, A. N., McCombe, P., Steingo, B., Van Wijmeersch, B., Margolin, D. H., Thangavelu, K., Rodriguez, C. E. and Vermersch, P. (2016). Durable improvement in clinical outcomes in treatmentnaive patients with relapsing-remitting multiple sclerosis who switched from SC IFNB-1a to alemtuzumab (care-MS I extension study 4-year follow-up). 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

Durable improvement in clinical outcomes in treatmentnaive patients with relapsing-remitting multiple sclerosis who switched from SC IFNB-1a to alemtuzumab (care-MS I extension study 4-year follow-up)

2016

Conference Publication

Pregnancy Outcomes in Alemtuzumab-Treated Patients with Rrms

Rog, David, Chambers, Christina, McCombe, Pamela, Otero, Susana, Hellwig, Kerstin, Margolin, David, Thangavelu, Karthinathan and Oh, Jiwon (2016). Pregnancy Outcomes in Alemtuzumab-Treated Patients with Rrms. Annual Meeting of the Association-of-British-Neurologists (ABN), Brighton, England, May 17-19, 2016. LONDON: BMJ PUBLISHING GROUP. doi: 10.1136/jnnp-2016-315106.155

Pregnancy Outcomes in Alemtuzumab-Treated Patients with Rrms

2016

Conference Publication

Pregnancy protects against long-term disability accrual in relapsing-remitting MS

Jokubaitis, V. G., Kalincik, T., Lorscheider, J., Spelman, T., Horakova, D., Duquette, P., Girard, M., Prat, A., Izquierdo, G., Grammond, P., Pucci, E., Grand'Maison, F., Granella, F., Sola, P., Bergamaschi, R., Iuliano, G., Spitaleri, D., Hodgkinson, S., Olascoaga, J., Verheul, F., McCombe, P., Rozsa, C., Lechner-Scott, J., Terzi, M., Hughes, S., Saladino, M. -L., Lugaresi, A., Trojano, M. and Butzkueven, H. (2016). Pregnancy protects against long-term disability accrual in relapsing-remitting MS. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

Pregnancy protects against long-term disability accrual in relapsing-remitting MS

2016

Conference Publication

Individual response to disease modifying therapies: a global observational cohort study

Kalincik, T., Sobisek, L., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Izquierdo, G., Lugaresi, A., Girard, M., Prat, A., Duquette, P., Grammond, P., Sola, P., Hupperts, R., Grand'Maison, F., Pucci, E., Boz, C., Alroughani, R., Van Pesch, V., Lechner-Scott, J., Terzi, M., Bergamaschi, R., Iuliano, G., Granella, F., Spitaleri, D., Shaygannejad, V., Oreja-Guevara, C., Slee, M. ... Butzkueven, H. (2016). Individual response to disease modifying therapies: a global observational cohort study. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

Individual response to disease modifying therapies: a global observational cohort study

2016

Conference Publication

Alemtuzumab provides durable improvements in clinical outcomes in treatment-naive patients with active relapsing-remitting multiple sclerosis over 6 years in the absence of continuous treatment (CARE-MS I).

Coles, A. J., Boyko, A. N., Cohen, J. A., De Seze, J., Fox, E. J., Havrdova, E., Hartung, H. -P., Inshasi, J. S., McCombe, P., Selmaj, K. W., Vermersch, P., Van Wijmeersch, B., Margolin, D. H., Thangavelu, K., Rodriguez, C. E. and Montalban, X. (2016). Alemtuzumab provides durable improvements in clinical outcomes in treatment-naive patients with active relapsing-remitting multiple sclerosis over 6 years in the absence of continuous treatment (CARE-MS I).. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

Alemtuzumab provides durable improvements in clinical outcomes in treatment-naive patients with active relapsing-remitting multiple sclerosis over 6 years in the absence of continuous treatment (CARE-MS I).

2016

Conference Publication

Comparison of 5-year treatment outcomes between alemtuzumab versus natalizumab, fingolimod and interferon beta-1a

Kalincik, T., Brown, J. W., Robertson, N., Willis, M., Scolding, N., Pearson, O., Ziemssen, T., Hutchinson, M., McGuigan, C., Jokubaitis, V., Spelman, T., Horakova, D., Havrdova, E., Trojano, M., Izquierdo, G., Lugaresi, A., Prat, A., Girard, M., Duquette, P., Grammond, P., Alroughani, R., Pucci, E., Sola, P., Hupperts, R., Lechner-Scott, J., Fernandez Bolanos, R., Terzi, M., Van Pesch, V., Rozsa, C. ... Coles, A. (2016). Comparison of 5-year treatment outcomes between alemtuzumab versus natalizumab, fingolimod and interferon beta-1a. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

Comparison of 5-year treatment outcomes between alemtuzumab versus natalizumab, fingolimod and interferon beta-1a

2016

Conference Publication

Australian cladribine experience

Kalincik, T., Lizak, N., Jokubaitis, V., Butler, E., Lechner-Scott, J., Slee, M., McCombe, P., Shaw, C., Skibina, O., Vucic, S., Shuey, N., Barnett, M., Parratt, J., Butzkueven, H. and Hodgkinson, S. (2016). Australian cladribine experience. 32nd Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS), London, England, Sep 14-17, 2016. LONDON: SAGE PUBLICATIONS LTD.

Australian cladribine experience

2015

Journal Article

Targeted assessment of lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis

Devine, Matthew S., Ballard, Emma, O'Rourke, Peter, Kiernan, Matther C., Mccombe, Pamela A. and Henderson, Robert D. (2015). Targeted assessment of lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 17 (3-4), 1-7. doi: 10.3109/21678421.2015.1125502

Targeted assessment of lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis

2015

Conference Publication

Defining secondary progressive multiple sclerosis

Lorscheider, Johannes, Buzzard, Katherine, Jokubaitis, Vilija, Spelman, Tim, Lechner-Scott, Jeannette, McCombe, Pam, Vucic, Steve, Barnett, Michael, Butzkueven, Helmut and Kalincik, Tomas (2015). Defining secondary progressive multiple sclerosis. MS Research Australia Progress in MS Research Conference, Melbourne Australia, Oct 29-30, 2015. LONDON: SAGE PUBLICATIONS LTD.

Defining secondary progressive multiple sclerosis