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2012

Journal Article

Gene expression in the spinal cord in female Lewis rats with experimental autoimmune encephalomyelitis induced with myelin basic proteins

Inglis, Hayley R., Greer, Judith M. and McCombe, Pamela A. (2012). Gene expression in the spinal cord in female Lewis rats with experimental autoimmune encephalomyelitis induced with myelin basic proteins. PLoS One, 7 (11), e48555.1-e48555.15. doi: 10.1371/journal.pone.0048555

Gene expression in the spinal cord in female Lewis rats with experimental autoimmune encephalomyelitis induced with myelin basic proteins

2012

Journal Article

Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial

Cohen, Jeffrey A., Coles, Alasdair J., Arnold, Douglas L., Confavreux, Christian, Fox, Edward J., Hartung, Hans-Peter, Havrdova, Eva, Selmaj, Krzysztof W., Weiner, Howard L., Fisher, Elizabeth, Brinar, Vesna V., Giovannoni, Gavin, Stojanovic, Miroslav, Ertik, Bella I., Lake, Stephen L., Margolin, David H., Panzara, Michael A., Compston, D. Alastair S., CARE-MS I investigators and McCombe, Pamela (2012). Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial. Lancet, 380 (9856), 1819-1828. doi: 10.1016/S0140-6736(12)61769-3

Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial

2012

Journal Article

Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial

Coles, Alasdair J., Twyman, Cary L., Arnold, Douglas L., Cohen, Jeffrey A., Confavreux, Christian, Fox, Edward J., Hartung, Hans-Peter, Havrdova, Eva, Selmaj, Krzysztof W., Weiner, Howard L., Miller, Tamara, Fisher, Elizabeth, Sandbrink, Rupert, Lake, Stephen L., Margolin, David H., Oyuela, Pedro, Panzara, Michael A., Compston, D. Alastair S., CARE-MS II investigators and McCombe, Pamela Ann (2012). Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial. Lancet, 380 (9856), 1829-1839. doi: 10.1016/S0140-6736(12)61768-1

Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial

2012

Journal Article

The relationship between Bayesian motor unit number estimation and histological measurements of motor neurons in wild-type and SOD1(G93A) mice

Ngo, S. T., Baumann, F., Ridall, P. G., Pettitt, A. N., Henderson, R. D., Bellingham, M. C. and McCombe, P. A. (2012). The relationship between Bayesian motor unit number estimation and histological measurements of motor neurons in wild-type and SOD1(G93A) mice. Clinical Neurophysiology, 123 (10), 2080-2091. doi: 10.1016/j.clinph.2012.01.028

The relationship between Bayesian motor unit number estimation and histological measurements of motor neurons in wild-type and SOD1(G93A) mice

2012

Journal Article

Quantitative studies of lower motor neuron degeneration in amyotrophic lateral sclerosis: evidence for exponential decay of motor unit numbers and greatest rate of loss at the site of onset

Baumann, F., Henderson, R. D., Ridall, P. Gareth, Pettitt, A. N. and McCombe, Pamela A. (2012). Quantitative studies of lower motor neuron degeneration in amyotrophic lateral sclerosis: evidence for exponential decay of motor unit numbers and greatest rate of loss at the site of onset. Clinical Neurophysiology, 123 (10), 2092-2098. doi: 10.1016/j.clinph.2012.03.007

Quantitative studies of lower motor neuron degeneration in amyotrophic lateral sclerosis: evidence for exponential decay of motor unit numbers and greatest rate of loss at the site of onset

2012

Conference Publication

Gene expression in the spinal cord in MBP-EAE in pregnant and post-partum rats: implications for the effects of MS in pregnancy

Inglis, H., Greer, J. and McCombe, P. (2012). Gene expression in the spinal cord in MBP-EAE in pregnant and post-partum rats: implications for the effects of MS in pregnancy. 28th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis, Lyon France, Oct 10-13, 2012. LONDON: SAGE PUBLICATIONS LTD.

Gene expression in the spinal cord in MBP-EAE in pregnant and post-partum rats: implications for the effects of MS in pregnancy

2012

Journal Article

The role of epigenetic mechanisms and processes in autoimmune disorders

Greer, Judith M. and McCombe, Pamela A. (2012). The role of epigenetic mechanisms and processes in autoimmune disorders. Biologics: Targets and Therapy, 6, 307-327. doi: 10.2147/BTT.S24067

The role of epigenetic mechanisms and processes in autoimmune disorders

2012

Journal Article

Reduced levels of interleukin 33 and increased levels of soluble ST2 in subjects with amyotrophic lateral sclerosis

Lin, C. Y., Pfluger, C. M., Henderson, R. D. and McCombe, P. A. (2012). Reduced levels of interleukin 33 and increased levels of soluble ST2 in subjects with amyotrophic lateral sclerosis. Journal of Neuroimmunology, 249 (1-2), 93-95. doi: 10.1016/j.jneuroim.2012.05.001

Reduced levels of interleukin 33 and increased levels of soluble ST2 in subjects with amyotrophic lateral sclerosis

2012

Journal Article

Structural hemispheric asymmetries in the human precentral gyrus hand representation

Rose, S., Rowland, T., Pannek, K., Baumann, F., Coulthard, A., McCombe, P. and Henderson, R. (2012). Structural hemispheric asymmetries in the human precentral gyrus hand representation. Neuroscience, 210, 211-221. doi: 10.1016/j.neuroscience.2012.02.044

Structural hemispheric asymmetries in the human precentral gyrus hand representation

2012

Journal Article

Prolonged elevation of cytokine levels after human acute ischaemic stroke with evidence of individual variability

Yan, Jun, Greer, Judith M. and McCombe, Pamela A. (2012). Prolonged elevation of cytokine levels after human acute ischaemic stroke with evidence of individual variability. Journal of Neuroimmunology, 246 (1-2), 78-84. doi: 10.1016/j.jneuroim.2012.02.013

Prolonged elevation of cytokine levels after human acute ischaemic stroke with evidence of individual variability

2012

Journal Article

Frequency and function of regulatory T cells after ischaemic stroke in humans

Yan, Jun, Read, Stephen J., Henderson, Robert D., Hull, Renee, O'Sullivan, John D., McCombe, Pamela A. and Greer, Judith M. (2012). Frequency and function of regulatory T cells after ischaemic stroke in humans. Journal of Neuroimmunology, 243 (1-2), 89-94. doi: 10.1016/j.jneuroim.2011.12.019

Frequency and function of regulatory T cells after ischaemic stroke in humans

2012

Journal Article

Direct evidence of intra- and interhemispheric corticomotor network degeneration in amyotrophic lateral sclerosis: An automated MRI structural connectivity study

Rose, Stephen, Pannek, Kerstin, Bell, Christopher, Baumann, Fusun, Hutchinson, Nicole, Coulthard, Alan, McCombe, Pamela and Henderson, Robert (2012). Direct evidence of intra- and interhemispheric corticomotor network degeneration in amyotrophic lateral sclerosis: An automated MRI structural connectivity study. NeuroImage, 59 (3), 2661-2669. doi: 10.1016/j.neuroimage.2011.08.054

Direct evidence of intra- and interhemispheric corticomotor network degeneration in amyotrophic lateral sclerosis: An automated MRI structural connectivity study

2012

Journal Article

Impairments to the GH-IGF-I axis in hSOD1(G93A) mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis

Steyn, F. J., Ngo, S. T, Lee, J. D., Leong, J. W., Buckley, A. J., Veldhuis, J. D., McCombe, P. A., Chen, C. and Bellingham, M. C. (2012). Impairments to the GH-IGF-I axis in hSOD1(G93A) mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis. Endocrinology, 153 (8), 3735-3746. doi: 10.1210/en.2011-2171

Impairments to the GH-IGF-I axis in hSOD1(G93A) mice give insight into possible mechanisms of GH dysregulation in patients with amyotrophic lateral sclerosis

2012

Journal Article

Interleukin-6 Gene Promoter-572 C Allele may play a role in rate of disease progression in Multiple Sclerosis

Yan, Jun, Liu, Jia, Lin, Clement Yihao, Australia and New Zealand Multiple Sclerorsis Genetics Consortium, Csurhes, Peter A., Pender, Michael P., McCombe, Pamela A. and Greer, Judith M. (2012). Interleukin-6 Gene Promoter-572 C Allele may play a role in rate of disease progression in Multiple Sclerosis. International Journal of Molecular Sciences, 13 (10), 13667-13679. doi: 10.3390/ijms131013667

Interleukin-6 Gene Promoter-572 C Allele may play a role in rate of disease progression in Multiple Sclerosis

2012

Conference Publication

Investigation of gene mutations in the NFKBIA promoter region in patients with multiple sclerosis

Yan, J., Pender, M.P., Liu, J., McCombe, P.A., Greer, J.M. and ANZgene Consortium (2012). Investigation of gene mutations in the NFKBIA promoter region in patients with multiple sclerosis. Progress in MS Research Conference 2011, Melbourne, VIC, Australia, 26-28 October 2011. London, United Kingdom: Sage Publications.

Investigation of gene mutations in the NFKBIA promoter region in patients with multiple sclerosis

2012

Conference Publication

Changes in the gene expression and splicing in the CNS during pregnancy and post-partum in the rat

Inglis, H., Narayanan, R., Wallace, R., Greer, J. and McCombe, P. (2012). Changes in the gene expression and splicing in the CNS during pregnancy and post-partum in the rat. Progress in MS Research Conference 2011, Melbourne, VIC, Australia, 26-28 October 2011. London, United Kingdom: Sage Publications.

Changes in the gene expression and splicing in the CNS during pregnancy and post-partum in the rat

2012

Conference Publication

Increased expression of the hypoxia related genes in peripheral blood cells of subjects with acute ischaemic stroke

McCombe, Pamela, Liu, Jia, Yan, Jun and Greer, Judith (2012). Increased expression of the hypoxia related genes in peripheral blood cells of subjects with acute ischaemic stroke. 11th International Congress of Neuroimmunology (ISNI), Boston MA., United States, 4-8 November 2012. Amsterdam, The Netherlands: Elsevier.

Increased expression of the hypoxia related genes in peripheral blood cells of subjects with acute ischaemic stroke

2011

Journal Article

Guillain-Barré Syndrome: Modern theories of etiology

Hardy, Todd A., Blum, Stefan, McCombe, Pamela A. and Reddel, Stephen W. (2011). Guillain-Barré Syndrome: Modern theories of etiology. Current Allergy and Asthma Reports, 11 (3), 197-204. doi: 10.1007/s11882-011-0190-y

Guillain-Barré Syndrome: Modern theories of etiology

2011

Journal Article

Use and monitoring of low dose rituximab in myasthenia gravis

Blum, Stefan, Gillis, David, Brown, Helen, Boyle, Richard, Henderson, Robert, Heyworth-Smith, David, Hogan, Patrick, Kubler, Paul, Lander, Cecilie, Limberg, Nicole, Pillans, Peter, Prain, Kerri, Staples, Christopher, Walsh, Michael, McCombe, Pamela and Wong, Richard (2011). Use and monitoring of low dose rituximab in myasthenia gravis. Journal of Neurology, Neurosurgery and Psychiatry, 82 (6), 659-663. doi: 10.1136/jnnp.2010.220475

Use and monitoring of low dose rituximab in myasthenia gravis

2011

Journal Article

Role of gender in multiple sclerosis: Clinical effects and potential molecular mechanisms

Greer, Judith M. and McCombe, Pamela A. (2011). Role of gender in multiple sclerosis: Clinical effects and potential molecular mechanisms. Journal of Neuroimmunology, 234 (1-2), 7-18. doi: 10.1016/j.jneuroim.2011.03.003

Role of gender in multiple sclerosis: Clinical effects and potential molecular mechanisms