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2020 Journal Article Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levelsLee, Aven, Arachchige, Buddhika Jayakody, Reed, Sarah, Henderson, Robert, Aylward, James and McCombe, Pamela Ann (2020). Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levels. Journal of the Neurological Sciences, 409 116589, 116589. doi: 10.1016/j.jns.2019.116589 |
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Featured 2020 Journal Article Monocytes and neutrophils are associated with clinical features in amyotrophic lateral sclerosisMcGill, Raquel B., Steyn, Frederik J., Ngo, Shyuan T., Thorpe, Kathryn A., Heggie, Susan, Ruitenberg, Marc J., Henderson, Robert D., McCombe, Pamela A. and Woodruff, Trent M. (2020). Monocytes and neutrophils are associated with clinical features in amyotrophic lateral sclerosis. Brain Communications, 2 (1) fcaa013, fcaa013. doi: 10.1093/braincomms/fcaa013 |
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2020 Journal Article Cylindrical spirals in two families: clinical and genetic investigationsBeecroft, Sarah J., Olive, Montse, Gonzalez Quereda, Lidia, Gallano, Pia, Ojanguren, Isabel, McLean, Catriona, McCombe, Pamela, Laing, Nigel G. and Ravenscroft, Gianina (2020). Cylindrical spirals in two families: clinical and genetic investigations. Neuromuscular Disorders, 30 (2), 151-158. doi: 10.1016/j.nmd.2019.12.006 |
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2020 Journal Article Clinical and therapeutic predictors of disease outcomes in AQP4-IgG+ neuromyelitis optica spectrum disorderKunchok, Amy, Malpas, Charles, Nytrova, Petra, Havrdova, Eva Kubala, Alroughani, Raed, Terzi, Murat, Yamout, Bassem, Hor, Jyh Yung, Karabudak, Rana, Boz, Cavit, Ozakbas, Serkan, Olascoaga, Javier, Simo, Magdolna, Granella, Franco, Patti, Francesco, McCombe, Pamela, Csepany, Tunde, Singhal, Bhim, Bergamaschi, Roberto, Fragoso, Yara, Al-Harbi, Talal, Turkoglu, Recai, Lechner-Scott, Jeannette, Laureys, Guy, Oreja-Guevara, Celia, Pucci, Eugenio, Sola, Patrizia, Ferraro, Diana, Altintas, Ayse ... Kalincik, Tomas (2020). Clinical and therapeutic predictors of disease outcomes in AQP4-IgG+ neuromyelitis optica spectrum disorder. Multiple Sclerosis and Related Disorders, 38 101868, 1-8. doi: 10.1016/j.msard.2019.101868 |
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2020 Journal Article The clinical profile of NMOSD in Australia and New ZealandBukhari, Wajih, Clarke, Laura, O’Gorman, Cullen, Khalilidehkordi, Elham, Arnett, Simon, Prain, Kerri M., Woodhall, Mark, Silvestrini, Roger, Bundell, Christine S., Ramanathan, Sudarshini, Abernethy, David, Bhuta, Sandeep, Blum, Stefan, Boggild, Mike, Boundy, Karyn, Brew, Bruce J., Brownlee, Wallace, Butzkueven, Helmut, Carroll, William M., Chen, Celia, Coulthard, Alan, Dale, Russell C., Das, Chandi, Dear, Keith, Fabis-Pedrini, Marzena J., Fulcher, David, Gillis, David, Hawke, Simon, Heard, Robert ... Broadley, Simon A. (2020). The clinical profile of NMOSD in Australia and New Zealand. Journal of Neurology, 267 (5), 1431-1443. doi: 10.1007/s00415-020-09716-4 |
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2020 Conference Publication Postpartum Relapse After First On-Study Pregnancy in RRMS Patients Treated With Alemtuzumab in the Phase 2 and 3 Clinical Development Program Over 8 YearsCelius, Elisabeth G., Oh, Jiwon, Achiron, Anat, Compston, D. Alastair S., Devonshire, Virginia, Hellwig, Kerstin, Hutton, George J., McCombe, Pamela, Moore, Marie, Simm, Renata Faria, Sousa, Livia, Vincent, Stephen G., Chung, Luke, Daizadeh, Nadia, Mitchell, Colin and Rog, David (2020). Postpartum Relapse After First On-Study Pregnancy in RRMS Patients Treated With Alemtuzumab in the Phase 2 and 3 Clinical Development Program Over 8 Years. Annual Meeting of the American Academy of Neurology, Toronto, Canada, 25 April - 1 May 2020. Philadelphia, PA United States: Lippincott Williams & Wilkins. |
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2020 Journal Article Progression and survival of patients with motor neuron disease relative to their fecal microbiotaNgo, Shyuan T., Restuadi, Restuadi, McCrea, Allan F., Van Eijk, Ruben P., Garton, Fleur, Henderson, Robert D., Wray, Naomi R., McCombe, Pamela A. and Steyn, Frederik J. (2020). Progression and survival of patients with motor neuron disease relative to their fecal microbiota. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 21 (7-8), 1-14. doi: 10.1080/21678421.2020.1772825 |
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2020 Journal Article Human brain neurons express a novel splice variant of excitatory amino acid transporter 5 (hEAAT5v)Lee, Aven, Balcar, Vladimir J., McCombe, Pamela and Pow, David V. (2020). Human brain neurons express a novel splice variant of excitatory amino acid transporter 5 (hEAAT5v). Journal of Comparative Neurology, 528 (17) cne.24907, 3134-3142. doi: 10.1002/cne.24907 |
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2020 Conference Publication Cladribine: a multicentre Long-term efficacy Biomarker Australian Study (CLOBAS)L-Scott, J., Maltby, V., Lydon, A., Monif, M., Kilpatrick, T., Butzkueven, H., Taylor, B., McCombe, P., Hodgkinson, S., Fabis-Pedrini, M., Kermode, A., Barnett, M. and Kalincik, Tomas (2020). Cladribine: a multicentre Long-term efficacy Biomarker Australian Study (CLOBAS). Conference of the Pan Asian Committee for Treatment and Research in Multiple Sclerosis (PACTRIMS), Singapore, Singapore, 13-15 November 2019. London, United Kingdom: Sage. |
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2020 Conference Publication Clinical experience with cladribine in patients with relapsing-remitting multiple sclerosisHodgkinson, S., Lizak, N., Butler, E., Lechner-Scott, J., Slee, M., McCombe, P., Shaw, C., Skibina, O., Vucic, S., Shuey, N., Barnett, M., Parratt, J., Butzkueven, H., Jack, D., Fabris, J., Kalincik, T. and Jokubaitis, V. G. (2020). Clinical experience with cladribine in patients with relapsing-remitting multiple sclerosis. Conference of the Pan-Asian-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (PACTRIMS), Singapore, Singapore, 13-15 November 2019. London, United Kingdom: Sage. |
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2020 Conference Publication Alemtuzumab Improves Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in RRMS Patients Over 8 Years: CARE-MS I Follow-up (TOPAZ Study)Hartung, H-P, Comi, G., Arnold, D. L., Boyko, A. N., Havrdova, E. K., Inshasi, J. S., McCombe, P., Nakamura, K., Oreja-Guevara, C., Pelletier, D., Pozzilli, C., Selmaj, K. W., Scott, T. F., Chung, L., Daizadeh, N., Afsar, S. and Van Wijmeersch, B. (2020). Alemtuzumab Improves Clinical and MRI Disease Activity Outcomes, Including Slowing of Brain Volume Loss, in RRMS Patients Over 8 Years: CARE-MS I Follow-up (TOPAZ Study). In: Conference of the Pan Asian Committee for Treatment and Research in Multiple Sclerosis (PACTRIMS), Singapore, Singapore, (NP60-NP61). 13-15 November 2019. |
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2020 Book Chapter Sexual dimorphism in the immune systemMcCombe, Pamela A. and Greer, Judith M. (2020). Sexual dimorphism in the immune system. The autoimmune diseases. (pp. 419-428) edited by Noel R. Rose and Ian R. Mackay. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-812102-3.00024-5 |
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2020 Conference Publication Efficacy Outcomes in RRMS Patients Who Switched From SC IFNB-1a in CARE-MS I and II to Alemtuzumab in the Extension Studies: 7-Year Follow-upPelletier, D., Arnold, D. L., Bass, A. D., Boyko, A. N., Broadley, S., Comi, G., McCombe, P., Montalban, X., Pozzilli, C., Rovira, A., Selmaj, K. W., Singer, B. A., Vermersch, P., Chung, L., Poole, E. and Wray, S. (2020). Efficacy Outcomes in RRMS Patients Who Switched From SC IFNB-1a in CARE-MS I and II to Alemtuzumab in the Extension Studies: 7-Year Follow-up. Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum, West Palm Beach, FL, United States, 27-29 February 2020. London, United Kingdom: Sage Publications. |
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2019 Journal Article Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelinationTea, Fiona, Lopez, Joseph A., Ramanathan, Sudarshini, Merheb, Vera, Lee, Fiona X. Z., Zou, Alicia, Pilli, Deepti, Patrick, Ellis, van der Walt, Anneke, Monif, Mastura, Tantsis, Esther M., Yiu, Eppie M., Vucic, Steve, Henderson, Andrew P. D., Fok, Anthony, Fraser, Clare L., Lechner-Scott, Jeanette, Reddel, Stephen W., Broadley, Simon, Barnett, Michael H., Brown, David A., Lunemann, Jan D., Dale, Russell C., Brilot, Fabienne, Sinclair, Adriane, Kermode, Allan G., Kornberg, Andrew, Bye, Annie, McGettigan, Benjamin ... Australasian and New Zealand MOG Study Group (2019). Characterization of the human myelin oligodendrocyte glycoprotein antibody response in demyelination. Acta Neuropathologica Communications, 7 (1) 145. doi: 10.1186/s40478-019-0786-3 |
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2019 Conference Publication Comparative effectiveness of natalizumab and fingolimod in different subgroups of patients with relapsing-remitting multiple sclerosisSharmin, S., Lefort, M., Andersen, J., Horakova, D., Havrdova, E. K., Alroughani, R., Izquierdo, G., Eichau, S., Ozakbas, S., Butzkueven, H., Patti, F., Onofrj, M., Lugaresi, A., Terzi, M., Grammond, P., Grand'Maison, F., Yamout, B., Prat, A., Girard, M., Duquette, P., Boz, C., Trojano, M., McCombe, P., Slee, M., Lechner-Scott, J., Turkoglu, R., Sola, P., Ferraro, D., Granella, F. ... Kalincik, T. (2019). Comparative effectiveness of natalizumab and fingolimod in different subgroups of patients with relapsing-remitting multiple sclerosis. 35th Congress of the European-Committee-for-Treatment-and-Research-in-Multiple-Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm Sweden, Sep 11-13, 2019. LONDON: SAGE PUBLICATIONS LTD. |
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2019 Conference Publication Determinants of therapeutic lag in relapsing multiple sclerosisRoos, I., Frascoli, F., Horakova, D., Havrdova, E. K., Trojano, M., Izquierdo, G., Eichau, S., Patti, F., Prat, A., Girard, M., Duquette, P., Onofr, M., Lugaresi, A., Grammond, P., Ozakbas, S., Sola, P., Ferraro, D., Bergamaschi, R., Cartechini, E., Sa, M. J., Boz, C., Grand'Maison, F., Lechner-Scott, J., Terzi, M., Granella, F., Alroughani, R., Iuliano, G., Hupperts, R., Spitaleri, D. ... Kalincik, T. (2019). Determinants of therapeutic lag in relapsing multiple sclerosis. 35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm, Sweden, 11-13 September 2019. London, United Kingdom: Sage Publications. |
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2019 Conference Publication Introducing Machine Learning for full MS patient trajectories improves predictions for disability score progressionDe Brouwer, E., Peeters, L., Becker, T., Altintas, A., Soysal, A., Van Wijmeersch, B., Boz, C., Oreja-Guevara, C., Gobbi, C., Solaro, C., Ramo, C., Spitaleri, D. L., Maimone, D., Aguera-Morales, E., Cartechini, E., Butler, E., Havrdova, E., Patti, F., Granella, F., Grand'Maison, F., Moore, F., Verheul, F., Iuliano, G., Butzkueven, H., Lechner-Scott, J., Kuhle, J., Sanchez Menoyo, J. L., Rojas, J. I., Prevost, J. ... Moreau, Y. (2019). Introducing Machine Learning for full MS patient trajectories improves predictions for disability score progression. 35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm, Sweden, 11-13 September 2019. London, United Kingdom: Sage Publications. |
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2019 Conference Publication Aggressive form of multiple sclerosis can be predicted early after disease onsetMalpas, C. B., Manouchehrinia, A., Sharmin, S., Roos, I., Horakova, D., Havrdova, E. K., Trojano, M., Izquierdo, G., Eichau, S., Bergamaschi, R., Sola, P., Ferraro, D., Lugaresi, A., Prat, A., Girard, M., Duquette, P., Grammond, P., Grand'Maison, F., Ozakbas, S., Van Pesch, V., Granella, F., Hupperts, R., Pucci, E., Boz, C., Iuliano, G., Sidhom, Y., Gouider, R., Spitaleri, D., Butzkueven, H. ... Kalincik, T. (2019). Aggressive form of multiple sclerosis can be predicted early after disease onset. 35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm, Sweden, 11-13 September 2019. London, United Kingdom: Sage Publications. |
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2019 Conference Publication Predicting long-term sustained disability progression in multiple sclerosisSharmin, S., Malpas, C., Horakova, D., Havrdova, E. K., Izquierdo, G., Eichau, S., Trojano, M., Prat, A., Girard, M., Duquette, P., Onofrj, M., Lugaresi, A., Grand'Maison, F., Grammond, P., Sola, P., Ferraro, D., Terzi, M., Hupperts, R., Alroughani, R., Boz, C., Shaygannejad, V., Van Pesch, V., Cartechini, E., Kappos, L., Lechner-Scott, J., Bergamaschi, R., Turkoglu, R., Solaro, C., Ramo-Tello, C. ... Kalincik, T. (2019). Predicting long-term sustained disability progression in multiple sclerosis. 35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm, Sweden, 11-13 September 2019. London, United Kingdom: Sage Publications. |
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2019 Conference Publication Personalizing treatment effect based on patient's baseline profile: a statistical modelling approach applied to randomized clinical trial and observational study dataBovis, F., Kalincik, T., Lublin, F., Cutter, G., Malpas, C., Horakova, D., Havrdova, E. Kubala, Trojano, M., Prat, A., Girard, M., Duquette, P., Onofrj, M., Lugaresi, A., Izquierdo, G., Eichau, S., Patti, F., Terzi, M., Grammond, P., Bergamaschi, R., Sola, P., Ferraro, D., Ozakbas, S., Iuliano, G., Boz, C., Hupperts, R., Grand'Maison, F., Oreja-Guevara, C., Van Pesch, V., Cartechini, E. ... Sormani, M. P. (2019). Personalizing treatment effect based on patient's baseline profile: a statistical modelling approach applied to randomized clinical trial and observational study data. 35th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) / 24th Annual Conference of Rehabilitation in MS, Stockholm, Sweden, 11-13 September 2019. London, United Kingdom: Sage Publications. |
