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2009

Conference Publication

Genetic and Environmental Influences on the Co-morbidity Between Depression, Panic Disorder, Agoraphobia, and Social Phobia: A Twin Study

Mosing, Miriam A., Gordon, Scott D., Medland, Sarah E., Statham, Dixie J., Nelson, Elliot C., Heath, Andrew C., Martin, Nicholas G. and Wray, Naomi R. (2009). Genetic and Environmental Influences on the Co-morbidity Between Depression, Panic Disorder, Agoraphobia, and Social Phobia: A Twin Study. United States: John Wiley & Sons, Inc.. doi: 10.1002/da.20611

Genetic and Environmental Influences on the Co-morbidity Between Depression, Panic Disorder, Agoraphobia, and Social Phobia: A Twin Study

2009

Journal Article

Estimating Effects and Making Predictions from Genome-Wide Marker Data

Goddard, Michael E., Wray, Naomi R., Verbyla, Klara and Visscher, Peter M. (2009). Estimating Effects and Making Predictions from Genome-Wide Marker Data. Statistical Science, 24 (4), 517-529. doi: 10.1214/09-STS306

Estimating Effects and Making Predictions from Genome-Wide Marker Data

2009

Journal Article

Accurate, Large-Scale Genotyping of 5HTTLPR and Flanking Single Nucleotide Polymorphisms in an Association Study of Depression, Anxiety, and Personality Measures

Naomi R. Wray, Michael R. James, Scott D. Gordon, Troy Dumenil, Leanne Ryan, William L. Coventry, Dixie J. Statham, Michele L. Pergadia, Pamela A.F. Madden, Andrew C. Heath, Grant W. Montgomery and Nicholas G. Martin (2009). Accurate, Large-Scale Genotyping of 5HTTLPR and Flanking Single Nucleotide Polymorphisms in an Association Study of Depression, Anxiety, and Personality Measures. Biological Psychiatry, 66 (5), 468-476. doi: 10.1016/j.biopsych.2009.04.030

Accurate, Large-Scale Genotyping of 5HTTLPR and Flanking Single Nucleotide Polymorphisms in an Association Study of Depression, Anxiety, and Personality Measures

2009

Conference Publication

Meta-analysis of genome-wide association results in > 10.000 individuals for the big five personality traits

de Moor, Marleen H. M., Boomsma, Dorret, I, de Geus, Eco J. C., Willemsen, Gonneke, Hottenga, Jouke-Jan, Distel, Marijn A., Abecasis, Goncalo R., Terracciano, Antonio, McCrae, Robert R., Costa, Paul T., Hartman, Catharina A., Spinhoven, Philip, Penninx, Brenda W., Esko, Tonu, Allik, Jueri, Realo, Anu, Metspalu, Andres, Hansell, Narelle K., Medland, Sarah E., Wray, Naomi R., Wright, Margie J., Martin, Nicholas G., Amin, Najaf, Aulchenko, Yurii S., Janssens, A. Cecile, Oostra, Ben A. and van Duijn, Cornelia M. (2009). Meta-analysis of genome-wide association results in > 10.000 individuals for the big five personality traits. 39th Annual Meeting of the Behavior Genetics Association, Mineapolis, MN, United States, 17-20 June 2009 . New York, NY, United States: Springer.

Meta-analysis of genome-wide association results in > 10.000 individuals for the big five personality traits

2009

Journal Article

Phenotypic and discordant-monozygotic analyses of stress and perceived social support as antecedents to or sequelae of risk for depression

Coventry, William L., Medland, Sarah E., Wray, Naomi R., Thorsteinsson, Einar B., Heath, Andrew C. and Byrne, Brain (2009). Phenotypic and discordant-monozygotic analyses of stress and perceived social support as antecedents to or sequelae of risk for depression. Twin Research And Human Genetics, 12 (5), 469-488. doi: 10.1375/twin.12.5.469

Phenotypic and discordant-monozygotic analyses of stress and perceived social support as antecedents to or sequelae of risk for depression

2009

Journal Article

Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

Psychiatric GWAS Consortium Coordinating Committee, Martin, N., Wray, N., Mowry, B. and Holliday, E. (2009). Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders. American Journal of Psychiatry, 166 (5), 540-556. doi: 10.1176/appi.ajp.2008.08091354

Genomewide Association Studies: History, Rationale, and Prospects for Psychiatric Disorders

2009

Journal Article

Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

Sullivan, P. F., de Geus, E. J. C., Willemsen, G., James, M. R., Smit, J. H., Zandbelt, T., Martin, N. G., Wray, N. R., Boomsma, D. I. and Penninx, B. W. J. H. (2009). Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Molecular Psychiatry, 14 (4), 359-375. doi: 10.1038/mp.2008.125

Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

2009

Journal Article

Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk

Evans, David M., Visscher, Peter M. and Wray, Naomi R. (2009). Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk. Human Molecular Genetics, 18 (18), 3525-3531. doi: 10.1093/hmg/ddp295

Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk

2009

Journal Article

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

International Schizophrenia Consortium and Wray, Naomi (2009). Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature, 460 (7256), 748-752. doi: 10.1038/nature08185

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

2008

Conference Publication

4. Use of monozygotic twins to investigate the relationship between 5HTTLPR genotype, depression and stressful life events: An application of Item Response Theory

Wray, Naomi R., Coventry, William L., James, Michael R., Montgomery, Grant W., Eaves, Lindon J. and Martin, Nicholas G. (2008). 4. Use of monozygotic twins to investigate the relationship between 5HTTLPR genotype, depression and stressful life events: An application of Item Response Theory.

4. Use of monozygotic twins to investigate the relationship between 5HTTLPR genotype, depression and stressful life events: An application of Item Response Theory

2008

Conference Publication

Genetic Linkage and Association Findings for DSM-IV Major Depressive Disorder: Is the Metabotropic Glutamate Receptor 7 Gene (<i>GRM7</i>) an Important Risk Factor for Depression in Smokers?

Pergadia, Michele L., Glowinski, Anne L., Agrawal, Arpana, Montgomery, Grant W., Loukola, Anu, Broms, Ulla, Saccone, Scott F., Korhonen, Tellervo, Wang, Jen C., Grant, Julia D., Lessov-Schalggar, Christina N., Todorov, Alexandre A., Wray, Naomi R., Heikkila, Kauko, Statham, Dixie J., Henders, Anjali, Campbell, Megan, Rice, John P., Todd, Richard D., Goate, Alison M., Peltonen, Leena, Heath, Andrew C., Kaprio, Jaakko, Martin, Nicholas G. and Madden, Pamela A. F. (2008). Genetic Linkage and Association Findings for DSM-IV Major Depressive Disorder: Is the Metabotropic Glutamate Receptor 7 Gene (GRM7) an Important Risk Factor for Depression in Smokers?. 38th Annual Meeting of the Behavior-Genetics-Association, Louisville Ky, Jun 28, 2008. NEW YORK: SPRINGER.

Genetic Linkage and Association Findings for DSM-IV Major Depressive Disorder: Is the Metabotropic Glutamate Receptor 7 Gene (<i>GRM7</i>) an Important Risk Factor for Depression in Smokers?

2008

Book Chapter

Use of Monozygotic Twins to Investigate the Relationship between 5HTTLPR Genotype, Depression and Stressful Life Events: An Application of Item Response Theory

Wray, Naomi R., Coventry, William L., James, Michael R., Montgomery, Grant W., Eaves, Lindon J. and Martin, Nicholas G. (2008). Use of Monozygotic Twins to Investigate the Relationship between 5HTTLPR Genotype, Depression and Stressful Life Events: An Application of Item Response Theory. Genetic Effects on Environmental Vulnerability to Disease. (pp. 48-59) wiley. doi: 10.1002/9780470696781.ch4

Use of Monozygotic Twins to Investigate the Relationship between 5HTTLPR Genotype, Depression and Stressful Life Events: An Application of Item Response Theory

2008

Journal Article

Suggestive linkage on chromosome 2, 8, and 17 for lifetime major depression

Middeldorp, CM, Sullivan, PF, Wray, NR, Hottenga, JJ, de Geus, EJC, van den Berg, M, Montgomery, GW, Coventry, WL, Statham, DJ, Andrews, G, Slagboom, PE, Boomsma, DI and Martin, NG (2008). Suggestive linkage on chromosome 2, 8, and 17 for lifetime major depression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 150B (3), 352-358. doi: 10.1002/ajmg.b.30817

Suggestive linkage on chromosome 2, 8, and 17 for lifetime major depression

2008

Journal Article

Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression

Wray, Naomi R., James, Michael R., Handoko, Herlina Y., Dumenil, Troy, Lind, Penelope A., Montgomery, Grant W. and Martin, Nicholas G. (2008). Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression. Psychiatric Genetics, 18 (5), 219-225. doi: 10.1097/YPG.0b013e3283050aee

Association study of candidate variants from brain-derived neurotrophic factor and dystrobrevin-binding protein 1 with neuroticism, anxiety, and depression

2008

Journal Article

Shared temperament risk factors for anorexia nervosa: a twin study

Wade, T. D., Tiggemann, M., Bulik, C. M., Fairburn, C. G., Wray, N. R. and Martin, N. G. (2008). Shared temperament risk factors for anorexia nervosa: a twin study. Psychosomatic Medicine, 70 (2), 239-244. doi: 10.1097/PSY.0b013e31815c40f1

Shared temperament risk factors for anorexia nervosa: a twin study

2008

Journal Article

Heritability in the genomics era — concepts and misconceptions

Visscher, Peter, Hill, William G. and Wray, Naomi (2008). Heritability in the genomics era — concepts and misconceptions. Nature Reviews Genetics, 9 (4), 255-266. doi: 10.1038/nrg2322

Heritability in the genomics era — concepts and misconceptions

2008

Book Chapter

Use of monozygotic twins to investigate the relationship between 5HTTLPR genotype, depression and stressful life events: an application of item response theory

Wray, Naomi R., Coventry, William L., James, Michael R., Montgomery, Grant W., Eaves, Lindon J. and Martin, Nicholas G. (2008). Use of monozygotic twins to investigate the relationship between 5HTTLPR genotype, depression and stressful life events: an application of item response theory. Genetic effects on environmental vulnerability to disease. (pp. 48-67) Chichester, United Kingdom: John Wiley & Sons. doi: 10.1002/9780470696781.ch4

Use of monozygotic twins to investigate the relationship between 5HTTLPR genotype, depression and stressful life events: an application of item response theory

2008

Journal Article

Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands

Wray, Naomi R., Middeldorp, Christel M., Birley, Andrew J., Gordon, Scott D., Sullivan, Patrick F., Visscher, Peter M., Nyholt, Dale R, Willemsen, Gonneke, de Geus, Eco J.C., Slagboom, P. Eline, Montgomery, Grant W., Martin, Nicholas G. and Boomsma, Dorret I. (2008). Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands. Archives of General Psychiatry, 65 (6), 649-658. doi: 10.1001/archpsyc.65.6.649

Genome-wide linkage analysis of multiple measures of neuroticism of 2 large cohorts from Australia and the Netherlands

2008

Journal Article

Association study of candidate variants of COMT with neuroticism, anxiety and depression

Wray, Naomi, James, Michael R., Dumenil, Troy, Handoko, Herlina Y., Lind, Penelope A., Montgomery, Grant W. and Martin, Nicholas G. (2008). Association study of candidate variants of COMT with neuroticism, anxiety and depression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 147B (7), 1314-1318. doi: 10.1002/ajmg.b.30744

Association study of candidate variants of COMT with neuroticism, anxiety and depression

2008

Journal Article

A whole genome association study of neuroticism using DNA pooling

Shifman, S., Bhomra, A., Smiley, S., Wray, N. R., James, M. R., Martin, N. G., Hettema, J. M., An, S. S., Neale, M. C., van den Oord, E. J., Kendler, K. S., Chen, X., Boomsma, D. I., Middeldorp, C. M., Hottenga, J. J., Slagboom, P. E. and Flint, J. (2008). A whole genome association study of neuroticism using DNA pooling. Molecular Psychiatry, 13 (3), 302-312. doi: 10.1038/sj.mp.4002048

A whole genome association study of neuroticism using DNA pooling