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2010 Journal Article Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1Crowley, Emily, O'Mara, Megan L., Kerr, Ian D. and Callaghan, Richard (2010). Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1. Febs Journal, 277 (19), 3974-3985. doi: 10.1111/j.1742-4658.2010.07789.x |
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2009 Journal Article ABC transporters: A riddle wrapped in a mystery inside an enigmaJones, Peter M., O'Mara, Megan L. and George, Anthony M. (2009). ABC transporters: A riddle wrapped in a mystery inside an enigma. Trends in Biochemical Sciences, 34 (10), 520-531. doi: 10.1016/j.tibs.2009.06.004 |
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2009 Journal Article Transmembrane helix 12 modulates progression of the ATP catalytic cycle in ABCB1Crowley, Emily, O'Mara, Megan L., Reynolds, Catherine, Tieleman, D. Peter, Storm, Janet, Kerr, Ian D. and Callaghan, Richard (2009). Transmembrane helix 12 modulates progression of the ATP catalytic cycle in ABCB1. Biochemistry, 48 (26), 6249-6258. doi: 10.1021/bi900373x |
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2009 Journal Article Structural arrangement of the transmission interface in the antigen ABC transport complex TAPOancea, Giani, O'Mara, Megan L., Bennett, W. F. Drew, Tieleman, D. Peter, Abele, Rupert and Tampé, Robert (2009). Structural arrangement of the transmission interface in the antigen ABC transport complex TAP. National Academy of Sciences. Proceedings, 106 (14), 5551-5556. doi: 10.1073/pnas.0811260106 |
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2009 Journal Article The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporterProcko, Erik, O'Mara, Megan L., Bennett, W. F. Drew, Tieleman, D. Peter and Gaudet, Rachelle (2009). The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter. FASEB Journal, 23 (5), 1287-1302. doi: 10.1096/fj.08-121855 |
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2008 Journal Article Non-linear intramolecular interactions and voltage sensitivity of a KV1 family potassium channel from Polyorchis penicillatus (Eschscholtz 1829)Klassen, Tara L., O'Mara, Megan L., Redstone, Megan, Spencer, Andrew N. and Gallin, Warren J. (2008). Non-linear intramolecular interactions and voltage sensitivity of a KV1 family potassium channel from Polyorchis penicillatus (Eschscholtz 1829). Journal of Experimental Biology, 211 (21), 3442-3453. doi: 10.1242/jeb.022608 |
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2008 Journal Article ATP-binding cassette transporters in Escherichia coliMoussatova, Anastassiia, Kandt, Christian, O'Mara, Megan L. and Tieleman, D. Peter (2008). ATP-binding cassette transporters in Escherichia coli. BBA: Biomembranes, 1778 (9), 1757-1771. doi: 10.1016/j.bbamem.2008.06.009 |
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2008 Journal Article Cytosolic region of TM6 in P-Glycoprotein: Topographical analysis and functional perturbation by site directed labelingStorm, Janet, Modok, Szabolcs, O’Mara, Megan L., Tieleman, D. Peter, Kerr, Ian D. and Callaghan, Richard (2008). Cytosolic region of TM6 in P-Glycoprotein: Topographical analysis and functional perturbation by site directed labeling. Biochemistry, 47 (12), 3615-3624. doi: 10.1021/bi7023089 |
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2008 Journal Article Structure-based interpretation of the mutagenesis database for the nucleotide binding domains of P-glycoproteinLawson, J., O'Mara, M. L. and Kerr, I. D. (2008). Structure-based interpretation of the mutagenesis database for the nucleotide binding domains of P-glycoprotein. BBA: Biomembranes, 1778 (2), 376-391. doi: 10.1016/j.bbamem.2007.10.021 |
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2007 Journal Article Residue G346 in transmembrane segment six is involved in inter-domain communication in P-GlycoproteinStorm, Janet, O’Mara, Megan L., Crowley, Emily H., Peall, Jonathan, Tieleman, D. Peter, Kerr, Ian D. and Callaghan, Richard (2007). Residue G346 in transmembrane segment six is involved in inter-domain communication in P-Glycoprotein. Biochemistry, 46 (35), 9899-9910. doi: 10.1021/bi700447p |
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2007 Journal Article P-glycoprotein models of the apo and ATP-bound states based on homology with Sav1866 and MalKO'Mara, Megan L. and Tieleman, D. Peter (2007). P-glycoprotein models of the apo and ATP-bound states based on homology with Sav1866 and MalK. FEBS Letters, 581 (22), 4217-4222. doi: 10.1016/j.febslet.2007.07.069 |
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2007 Conference Publication Determining the structural conformation of P-glycoprotein via homology modellingO'Mara, M. L. and Tieleman, D. P. (2007). Determining the structural conformation of P-glycoprotein via homology modelling. 51st Annual Meeting of the Biophysical-Society, Baltimore, United States, 3-7 March 2007. St. Louis, United States: Cell Press. |
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2006 Journal Article Mechanism and putative structure of B0-like neutral amino acid transportersO’Mara, M., Oakley, A. and Bröer, S. (2006). Mechanism and putative structure of B0-like neutral amino acid transporters. Journal of Membrane Biology, 213 (2), 111-118. doi: 10.1007/s00232-006-0879-3 |
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2006 Conference Publication Computer simulations of ABC transporter componentsOloo, Eliud, Kandt, Christian, O’Mara, Megan L. and Tieleman, D. Peter (2006). Computer simulations of ABC transporter components. 49th Annual Canadian Society of Biochemistry and Molecular and Cellular Biology Meeting, Ontario, Canada, 31 May- 4 June 2006. Ottowa, Canada: National Research Council of Canada. doi: 10.1139/O06-182 |
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2006 Conference Publication Investigating the mechanism of proton transfer through the bacterial ClC transporterO'Mara, Megan L., Yin, Jian, Hoyles, Matthew and Chung, Shin-Ho (2006). Investigating the mechanism of proton transfer through the bacterial ClC transporter. 50th Annual Meeting of the Biopysical-Society, Salt Lake City, Utah, U.S.A., 18-22 February, 2006. Bethesda, MD., U.S.A.: Cell Press for the Biophysical Society. |
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2005 Journal Article Homology model of the GABAA receptor examined using Brownian DynamicsO'Mara, Megan, Cromer, Brett, Parker, Michael and Chung, Shin-Ho (2005). Homology model of the GABAA receptor examined using Brownian Dynamics. Biophysical Journal, 88 (5), 3286-3299. doi: 10.1529/biophysj.104.051664 |
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2005 Conference Publication The reliability of relative cation-anion permeabilities deduced from reversal (dilution) potential measurements in ion channel studies, and Brownian dynamics predictionsBarry, PH and O'Mara, ML (2005). The reliability of relative cation-anion permeabilities deduced from reversal (dilution) potential measurements in ion channel studies, and Brownian dynamics predictions. Experimental Biology 2005 Meeting/35th International Congress of Physiological Sciences, San Diego Ca, Mar 31-Apr 06, 2005. BETHESDA: FEDERATION AMER SOC EXP BIOL. |
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2005 Conference Publication Simulations of ion permeation through a homology model of the GABA(A) receptorO'Mara, M. L., Cromer, B. A., Parker, M. W. and Chung, S. H. (2005). Simulations of ion permeation through a homology model of the GABA(A) receptor. 49th Annual Meeting of the Biopysical-Society, Long Beach, California, U.S.A., 12-16 February, 2005. Bethesda, MD., U.S.A.: Cell Press for the Biophysical Society. |
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2005 Conference Publication The reliability of relative cation-anion permeabilities deduced from reversal (dilution) potential measurements in ion channel studies, and Brownian dynamics predictionsBarry, P. H. and O'Mara, M. L. (2005). The reliability of relative cation-anion permeabilities deduced from reversal (dilution) potential measurements in ion channel studies, and Brownian dynamics predictions. Experimental Biology 2005 Meeting/35th International Congress of Physiological Sciences, San Diego, California, U.S.A., 31 March, - April, 2005. Bethesda, MD, U.S.A.: Federation of American Societies for Experimental Biology. |
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2005 Conference Publication Simulations of ion permeation through a homology model of the GABA(A) receptorO'Mara, ML, Cromer, BA, Parker, MW and Chung, SH (2005). Simulations of ion permeation through a homology model of the GABA(A) receptor. 49th Annual Meeting of the Biopysical-Society, Long Beach Ca, Feb 12-16, 2005. BETHESDA: BIOPHYSICAL SOCIETY. |
