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2024 Journal Article Metabolic aspects of genetic ion channel epilepsiesNeal, Elliott S., Xu, Weizhi and Borges, Karin (2024). Metabolic aspects of genetic ion channel epilepsies. Journal of Neurochemistry, 168 (12), 3911-3935. doi: 10.1111/jnc.15938 |
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2024 Journal Article “Brain propane’’: Propionate Fuels the Brain in Mice With Brain Energy DeficitsNeal, Elliott S. and Borges, Karin (2024). “Brain propane’’: Propionate Fuels the Brain in Mice With Brain Energy Deficits. Epilepsy Currents, 15357597241293843. doi: 10.1177/15357597241293843 |
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2024 Journal Article DREADD Microglia? Targeted Microglial Gi Activation in the Acute Phase can Reduce Seizure Severity, but is Detrimental in the Long TermBodea, Liviu-Gabriel and Borges, Karin (2024). DREADD Microglia? Targeted Microglial Gi Activation in the Acute Phase can Reduce Seizure Severity, but is Detrimental in the Long Term. Epilepsy Currents, 24 (6), 420-422. doi: 10.1177/15357597241279761 |
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2024 Journal Article Case for supporting astrocyte energetics in glucose transporter 1 deficiency syndromeXu, Weizhi and Borges, Karin (2024). Case for supporting astrocyte energetics in glucose transporter 1 deficiency syndrome. Epilepsia, 65 (8), 2213-2226. doi: 10.1111/epi.18013 |
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2024 Journal Article The benefits of “spoilt milk”: lactic acid can limit excitability via HCAR1Borges, Karin (2024). The benefits of “spoilt milk”: lactic acid can limit excitability via HCAR1. Epilepsy Currents, 24 (3), 206-208. doi: 10.1177/15357597241249037 |
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2024 Journal Article Transient anticonvulsant effects of time-restricted feeding in the 6-Hz mouse modelArmstrong, Oliver J., Neal, Elliott S., Vidovic, Diana, Xu, Weizhi and Borges, Karin (2024). Transient anticonvulsant effects of time-restricted feeding in the 6-Hz mouse model. Epilepsy and Behavior, 151 109618. doi: 10.1016/j.yebeh.2023.109618 |
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2024 Journal Article Brain energy metabolism: A roadmap for future researchRae, Caroline D., Baur, Joseph A., Borges, Karin, Dienel, Gerald, Díaz‐García, Carlos Manlio, Douglass, Starlette R., Drew, Kelly, Duarte, João M. N., Duran, Jordi, Kann, Oliver, Kristian, Tibor, Lee‐Liu, Dasfne, Lindquist, Britta E., McNay, Ewan C., Robinson, Michael B., Rothman, Douglas L., Rowlands, Benjamin D., Ryan, Timothy A., Scafidi, Joseph, Scafidi, Susanna, Shuttleworth, C. William, Swanson, Raymond A., Uruk, Gökhan, Vardjan, Nina, Zorec, Robert and McKenna, Mary C. (2024). Brain energy metabolism: A roadmap for future research. Journal of Neurochemistry, 168 (5), 910-954. doi: 10.1111/jnc.16032 |
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2023 Journal Article Vitamin B12 deficiency induces glucose intolerance, delays peak insulin levels and promotes ketogenesis in female ratsNeal, Elliott, Kumar, Vinod, Borges, Karin and Cuffe, James S.M. (2023). Vitamin B12 deficiency induces glucose intolerance, delays peak insulin levels and promotes ketogenesis in female rats. The Journal of Endocrinology, 256 (2) e220158, 1-16. doi: 10.1530/joe-22-0158 |
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2022 Journal Article Glyceryl triacetate feeding in mice increases plasma acetate levels but has no anticonvulsant effects in acute electrical seizure modelsXu, Weizhi, Neal, Elliott S., Plan, Manuel and Borges, Karin (2022). Glyceryl triacetate feeding in mice increases plasma acetate levels but has no anticonvulsant effects in acute electrical seizure models. Epilepsy and Behavior, 137 (Part A) 108964, 108964. doi: 10.1016/j.yebeh.2022.108964 |
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2022 Journal Article Potential new roles for glycogen in epilepsyDienel, Gerald A., Gillinder, Lisa, McGonigal, Aileen and Borges, Karin (2022). Potential new roles for glycogen in epilepsy. Epilepsia, 64 (1), 29-53. doi: 10.1111/epi.17412 |
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2022 Journal Article β-hydroxybutyrate and medium-chain fatty acids are metabolized by different cell types in mouse cerebral cortex slicesAndersen, Jens V., Westi, Emil W., Neal, Elliott S., Aldana, Blanca I. and Borges, Karin (2022). β-hydroxybutyrate and medium-chain fatty acids are metabolized by different cell types in mouse cerebral cortex slices. Neurochemical Research, 48 (1), 1-8. doi: 10.1007/s11064-022-03726-6 |
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2022 Journal Article Brain glycogen content is increased in the acute and interictal chronic stages of the mouse pilocarpine model of epilepsyYoung Seo, Gi, Neal, Elliott S., Han, Felicity, Vidovic, Diana, Nooru‐Mohamed, Fathima, Dienel, Gerald A., Sullivan, Mitchell A. and Borges, Karin (2022). Brain glycogen content is increased in the acute and interictal chronic stages of the mouse pilocarpine model of epilepsy. Epilepsia Open, 7 (2), 361-367. doi: 10.1002/epi4.12599 |
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2022 Book Chapter Triheptanoin in epilepsy and beyondBorges, Karin (2022). Triheptanoin in epilepsy and beyond. Ketogenic diet and metabolic therapies: expanded roles in health and disease. (pp. 493-507) edited by Susan A. Masino. Oxford, United Kingdom: Oxford University Press. |
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2022 Book Chapter Dietary management of canine epilepsyNeal, Elliott S., Xu, Weizhi and Borges, Karin (2022). Dietary management of canine epilepsy. A practical guide to seizure disorders in dogs and cats. (pp. 299-310) edited by Luisa De Risio and Karen Munana. Palm Beach, FL, United States: Edra Publsihing. |
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2021 Journal Article Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supplyAndersen, Jens V., Westi, Emil W., Jakobsen, Emil, Urruticoechea, Nerea, Borges, Karin and Aldana, Blanca I. (2021). Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply. Molecular Brain, 14 (1) 132, 1-13. doi: 10.1186/s13041-021-00842-2 |
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2021 Journal Article Sustained-release ketamine-loaded lipid-particulate system: in vivo assessment in miceXu, Weizhi, Maqbool, Faheem, Kumar, Vinod, Falconer, James R., Cui, Cedric S., Woodruff, Trent M., Borges, Karin, Whittaker, Andrew K., Smith, Maree T. and Han, Felicity Y. (2021). Sustained-release ketamine-loaded lipid-particulate system: in vivo assessment in mice. Drug Delivery and Translational Research, 12 (10), 2518-2526. doi: 10.1007/s13346-021-01093-3 |
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2021 Journal Article Fructose 1,6-bisphosphate is anticonvulsant and improves oxidative glucose metabolism within the hippocampus and liver in the chronic pilocarpine mouse epilepsy modelMcDonald, Tanya S., Neal, Elliott S. and Borges, Karin (2021). Fructose 1,6-bisphosphate is anticonvulsant and improves oxidative glucose metabolism within the hippocampus and liver in the chronic pilocarpine mouse epilepsy model. Epilepsy and Behavior, 122 108223, 1-9. doi: 10.1016/j.yebeh.2021.108223 |
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2021 Journal Article Dietary medium chain triglycerides for management of epilepsy: new data from human, dog, and rodent studiesHan, Felicity Y., Conboy‐Schmidt, Lisa, Rybachuk, Galena, Volk, Holger A., Zanghi, Brian, Pan, Yuanlong and Borges, Karin (2021). Dietary medium chain triglycerides for management of epilepsy: new data from human, dog, and rodent studies. Epilepsia, 62 (8) epi.16972, 1790-1806. doi: 10.1111/epi.16972 |
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2021 Journal Article CNS glucose metabolism in amyotrophic lateral sclerosis: a therapeutic target?Tefera, Tesfaye Wolde, Steyn, Frederik J., Ngo, Shyuan T. and Borges, Karin (2021). CNS glucose metabolism in amyotrophic lateral sclerosis: a therapeutic target?. Cell & Bioscience, 11 (1) 14, 14. doi: 10.1186/s13578-020-00511-2 |
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2021 Book Chapter Alterations in mitochondrial glucose carbon metabolism in epilepsy and targeted metabolic treatmentsHan, Felicity Y., McDonald, Tanya, Xu, Weizhi and Borges, Karin (2021). Alterations in mitochondrial glucose carbon metabolism in epilepsy and targeted metabolic treatments. Clinical bioenergetics: from pathophysiology to clinical translation. (pp. 653-677) edited by Sergej Ostojic. London, United Kingdom: Elsevier. doi: 10.1016/b978-0-12-819621-2.00029-2 |
