2017 Journal Article Metabolic dysfunctions in amyotrophic lateral sclerosis pathogenesis and potential metabolic treatmentsTefera, Tesfaye W. and Borges, Karin (2017). Metabolic dysfunctions in amyotrophic lateral sclerosis pathogenesis and potential metabolic treatments. Frontiers in Neuroscience, 10 (JAN) 611, 461-473. doi: 10.3389/fnins.2016.00611 |
2017 Conference Publication Anaplerotic triheptanoin preserves mitochondrial function and reduces oxidative stress in pilocarpine-induced status epilepticusTan, K. N., Carrasco-Pozo, C. and Borges, K. (2017). Anaplerotic triheptanoin preserves mitochondrial function and reduces oxidative stress in pilocarpine-induced status epilepticus. 28th International Symposium on Cerebral Blood Flow, Metabolism and Function / 13th International Conference on Quantification of Brain Function with PET, Berlin, Germany, 1-4 April 2017. London, United Kingdom: Sage Publications. |
2017 Book Chapter Triheptanoin epilepsy and beyondBorges, Karin (2017). Triheptanoin epilepsy and beyond. Ketogenic diet and metabolic therapies: expanded roles in health and disease. (pp. 336-346) edited by Susan A. Masino. New York NY, USA: Oxford University Press. |
2017 Conference Publication Cortical neuronal glucose metabolism is impaired at mid stage in the hSOD1(G93A) mouse model of amyotrophic lateral sclerosisTefera, T. and Borges, K. (2017). Cortical neuronal glucose metabolism is impaired at mid stage in the hSOD1(G93A) mouse model of amyotrophic lateral sclerosis. ISN-ESN Meeting, Paris, France, 20-24 August 2017. Chichester, West Sussex, United Kingdom: Wiley-Blackwell . |
2016 Journal Article Alternative fuels in epilepsy and amyotrophic lateral sclerosisTefera, Tesfaye W. , Tan, Kah Ni, McDonald, Tanya S. and Borges, Karin (2016). Alternative fuels in epilepsy and amyotrophic lateral sclerosis. Neurochemical Research, 42 (6), 1-11. doi: 10.1007/s11064-016-2106-7 |
2016 Journal Article The deleterious effect of cholesterol and protection by quercetin on mitochondrial bioenergetics of pancreatic β-cells, glycemic control and inflammation: in vitro and in vivo studiesCarrasco-Pozo, Catalina, Tan, Kah Ni, Reyes-Farias, Marjorie, De La Jara, Nicole, Ngo, Shyuan Thieu, Garcia-Diaz, Diego Fernando, Llanos, Paola, Cires, Maria Jose and Borges, Karin (2016). The deleterious effect of cholesterol and protection by quercetin on mitochondrial bioenergetics of pancreatic β-cells, glycemic control and inflammation: in vitro and in vivo studies. Redox Biology, 9, 229-243. doi: 10.1016/j.redox.2016.08.007 |
2016 Journal Article Triheptanoin protects motor neurons and delays the onset of motor symptoms in a mouse model of amyotrophic lateral sclerosisTefera, Tesfaye W., Wong, Yide, Barkl-Luke, Mallory E., Ngo, Shyuan T., Thomas, Nicola K., McDonald, Tanya S. and Borges, Karin (2016). Triheptanoin protects motor neurons and delays the onset of motor symptoms in a mouse model of amyotrophic lateral sclerosis. Plos One, 11 (8) e0161816, e0161816. doi: 10.1371/journal.pone.0161816 |
2016 Journal Article Tridecanoin is anticonvulsant, antioxidant, and improves mitochondrial functionTan, Kah Ni, Carrasco-Pozo, Catalina, McDonald, Tanya S., Puchowicz, Michelle and Borges, Karin (2016). Tridecanoin is anticonvulsant, antioxidant, and improves mitochondrial function. Journal Of Cerebral Blood Flow and Metabolism, 37 (6), 2035-2048. doi: 10.1177/0271678X16659498 |
2015 Journal Article Sulforaphane is anticonvulsant and improves mitochondrial functionCarrasco-Pozo, Catalina, Tan, Kah Ni and Borges, Karin (2015). Sulforaphane is anticonvulsant and improves mitochondrial function. Journal of Neurochemistry, 135 (5), 932-942. doi: 10.1111/jnc.13361 |
2015 Journal Article Modification of Astrocyte Metabolism as an Approach to the Treatment of Epilepsy: Triheptanoin and Acetyl-l-CarnitineHadera, Mussie Ghezu, McDonald, Tanya, Smeland, Olav B., Meisingset, Tore W., Eloqayli, Haytham, Jaradat, Saied, Borges, Karin and Sonnewald, Ursula (2015). Modification of Astrocyte Metabolism as an Approach to the Treatment of Epilepsy: Triheptanoin and Acetyl-l-Carnitine. Neurochemical Research, 41 (1-2), 86-95. doi: 10.1007/s11064-015-1728-5 |
2015 Journal Article Complex alterations in microglial M1/M2 markers during the development of epilepsy in two mouse modelsBenson, Melissa J., Manzanero, Silvia and Borges, Karin (2015). Complex alterations in microglial M1/M2 markers during the development of epilepsy in two mouse models. Epilepsia, 56 (6), 895-905. doi: 10.1111/epi.12960 |
2015 Journal Article A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy modelsBenson, Melissa J, Thomas, Nicola K, Talwar, Sahil, Hodson, Mark P, Lynch, Joseph W, Woodruff, Trent M and Borges, Karin (2015). A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy models. Neurobiology of Disease, 76, 87-97. doi: 10.1016/j.nbd.2015.02.004 |
2015 Conference Publication Tricaprin - a new anticonvulsant with multiple mechanisms of actionsBorges, K., Tan, K. N. and Carrasco, C. (2015). Tricaprin - a new anticonvulsant with multiple mechanisms of actions. 25th Biennial Meeting of the International Society for Neurochemistry Jointly with the 13th Meeting of the Asian Pacific Society for Neurochemistry in Conjunction with the 35th Meeting of the Australasian Neuroscience Society, Cairns, QLD Australia, 23-27 August 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jnc.13188 |
2015 Book Chapter Metabolic dysfunctions in epilepsy and novel metabolic treatment approachesTan, Kah Ni, McDonald, Tanya S. and Borges, Karin (2015). Metabolic dysfunctions in epilepsy and novel metabolic treatment approaches. Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease: Prevention and Therapy. (pp. 461-470) edited by Ronald R Watson and Victor R Preedy. Amsterdam, The Netherlands: Elsevier. doi: 10.1016/B978-0-12-411462-3.00048-5 |
2015 Book Chapter High Caloric diets for amyotrophic lateral sclerosisNgo, Shyuan T., Steyn, Frederik J., McCombe, Pamela A. and Borges, Karin (2015). High Caloric diets for amyotrophic lateral sclerosis. Bioactive nutraceuticals and dietary supplements in neurological and brain disease: prevention and therapy. (pp. 355-361) edited by Ronald Ross Watson and Victor R. Preedy. London, United Kingdom: Academic Press. doi: 10.1016/B978-0-12-411462-3.00036-9 |
2014 Journal Article Triheptanoin partially restores levels of tricarboxylic acid cycle intermediates in the mouse pilocarpine model of epilepsHadera, Mussie G., Smeland, Olav B., McDonald, Tanya S., Tan, Kah Ni, Sonnewald, Ursula and Borges, Karin (2014). Triheptanoin partially restores levels of tricarboxylic acid cycle intermediates in the mouse pilocarpine model of epileps. Journal of Neurochemistry, 129 (1), 107-119. doi: 10.1111/jnc.12610 |
2014 Journal Article Alterations of hippocampal glucose metabolism by even versus uneven medium chain triglyceridesMcDonald, Tanya S., Tan, Kah Ni, Hodson, Mark P. and Borges, Karin (2014). Alterations of hippocampal glucose metabolism by even versus uneven medium chain triglycerides. Journal Of Cerebral Blood Flow and Metabolism, 34 (1), 153-160. doi: 10.1038/jcbfm.2013.184 |
2014 Conference Publication Triheptanoin alters anaplerosis and glutamate production in the chronic pilocarpine model of epilepsyMcDonald, Tanya, Hodson, Mark and Borges, Karin (2014). Triheptanoin alters anaplerosis and glutamate production in the chronic pilocarpine model of epilepsy. EB2014: Experimental Biology 2014, San Diago, CA United States, 26-30 April, 2014. Bethesda, MD United States: Federation of American Societies for Experimental Biology. |
2013 Journal Article Slc10A4-what do we know about the function of this "secret ligand carrier" protein?Borges, Karin (2013). Slc10A4-what do we know about the function of this "secret ligand carrier" protein?. Experimental Neurology, 248, 258-261. doi: 10.1016/j.expneurol.2013.06.019 |
2013 Journal Article Anticonvulsant screening of luteolin in four mouse seizure modelsShaikh, Mohd Farooq, Tan, Kah Ni and Borges, Karin (2013). Anticonvulsant screening of luteolin in four mouse seizure models. Neuroscience Letters, 550, 195-199. doi: 10.1016/j.neulet.2013.06.065 |