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2005 Journal Article Transgenic expression of a viral oncoprotein exclusively in K14(+) epithelial cells results in peripheral but not central CD8 T cell toleranceLeggatt, G. R., Saunders, N., Dahler, A., Fernando, G. J., Matsumoto, K., Narayan, S., Linedale, R., Choyce, A. and Frazer, I. H. (2005). Transgenic expression of a viral oncoprotein exclusively in K14(+) epithelial cells results in peripheral but not central CD8 T cell tolerance. Tissue Antigens, 66 (5), 475-476. |
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2005 Journal Article Local inflammation is crucial for T cell mediated rejection of skin graft expressing foreign antigenZhong, J., De Kluyver, R., Leggatt, G. R., Fernando, G. J. and Frazer, I. H. (2005). Local inflammation is crucial for T cell mediated rejection of skin graft expressing foreign antigen. Tissue Antigens, 66 (5), 600-600. |
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2005 Journal Article Interferon-gamma is required for killing keratinocytes in vitro and in vivoDe Kluyver, R. L., Morritz, L., Leggatt, G. R., Harris, C., Lambert, P. F. and Frazer, I. H. (2005). Interferon-gamma is required for killing keratinocytes in vitro and in vivo. Tissue Antigens, 66 (5), 394-394. |
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2005 Journal Article Gene codon composition determines differentiation-dependent expression of a viral capsid gene in keratinocytes in vitro and in vivoZhao, Kong-Nan, Gu, WenYi, Fang, Ning Xia, Saunders, Nicholas A. and Frazer, Ian H. (2005). Gene codon composition determines differentiation-dependent expression of a viral capsid gene in keratinocytes in vitro and in vivo. Molecular And Cellular Biology, 25 (19), 8643-8655. doi: 10.1128/MCB.25.19.8643-8655.2005 |
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2005 Journal Article HPV-16 L1 VLP vaccine elicits a broad-spectrum of cytokine responses in whole bloodPinto, Ligia A., Castle, Philip E., Roden, Richard B., Harro, Clayton D., Lowy, Douglas R., Schiller, John T., Wallace, Dora, Williams, Marcus, Kopp, William, Frazer, Ian H., Berzofsky, Jay A. and Hildesheim, Allan (2005). HPV-16 L1 VLP vaccine elicits a broad-spectrum of cytokine responses in whole blood. Vaccine, 23 (27), 3555-3564. doi: 10.1016/j.vaccine.2005.01.146 |
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2005 Journal Article Activation of dendritic cells by human papillomavirus-like particles through TLR4 and NF-B-mediated signalling, moderated by TGF-betaYan, Mengyong, Peng, Judy, Jabbar, Ibtissam A., Liu, Xiaosong, Filguueira, Luis, Frazer, Ian H. and Thomas, Ranjeny (2005). Activation of dendritic cells by human papillomavirus-like particles through TLR4 and NF-B-mediated signalling, moderated by TGF-beta. Immunology and Cell Biology, 83 (1), 83-91. doi: 10.1111/j.1440-1711.2004.01291.x |
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2005 Journal Article Interferon-gamma, but not perforin or FasL, is required for killing keratinocytes in vitro and in vivodeKluyver, R. L., Moritz, L. and Frazer, I. H. (2005). Interferon-gamma, but not perforin or FasL, is required for killing keratinocytes in vitro and in vivo. Faseb Journal, 19 (5), A1438-A1438. |
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2005 Journal Article Overcoming original antigenic sin to generate effective immune responses in antigen primed hostLiu, X., Leggatt, G., Fernando, G. J. and Frazer, I. H. (2005). Overcoming original antigenic sin to generate effective immune responses in antigen primed host. Tissue Antigens, 66 (5), 481-481. |
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2004 Journal Article Functional memory CD8+ T cells can be generated in vivo without evident T helpAndrews, Melanie R., Peters, Tania, Khammanivong, Vithagna, Leggatt, Graham R., Frazer, Ian H. and Fernando, Germain J. P. (2004). Functional memory CD8+ T cells can be generated in vivo without evident T help. Vaccine, 23 (6), 739-742. doi: 10.1016/j.vaccine.2004.07.027 |
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2004 Journal Article Human growth hormone (hGH) presented by K14hGH-transgenic skin grafts induces a strong immune response but no graft rejectionZhong, J., Matsumoto, K., De Kluyver, R., Fernando, G. J. P., Leggatt, G. R. and Frazer, I. H. (2004). Human growth hormone (hGH) presented by K14hGH-transgenic skin grafts induces a strong immune response but no graft rejection. Journal of Investigative Dermatology, 123 (6), A113-A113. |
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2004 Journal Article Phase 1 study of HPV16-specific immunotherapy with E6E7 fusion protein and ISCOMATRIX (TM) adjuvant in women with cervical intraepithelial neoplasiaFrazer, Ian H., Quinn, Michael, Nicklin, Jim L., Tan, Jeffrey, Perrin, Lew C., Ng, Peng, O'Connor, Vivienne M., White, Olivia, Wendt, Ngaire, Martin, Juliet, Crowley, Jayne M., Edwards, Stirling J., McKenzie, Andrew W., Mitchell, Susan V., Maher, Darryl W., Pearse, Martin J. and Basser, Russell L. (2004). Phase 1 study of HPV16-specific immunotherapy with E6E7 fusion protein and ISCOMATRIX (TM) adjuvant in women with cervical intraepithelial neoplasia. Vaccine, 23 (2), 172-181. doi: 10.1016/j.vaccine.2004.05.013 |
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2004 Journal Article Major quantitative trait locus for eosinophil count is located on chromosome 2qEvans, DM, Zhu, G, Duffy, DL, Montgomery, GW, Frazer, IH and Martin, NG (2004). Major quantitative trait locus for eosinophil count is located on chromosome 2q. Journal of Allergy And Clinical Immunology, 114 (4), 826-830. doi: 10.1016/j.jaci.2004.05.060 |
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2004 Journal Article Tumour susceptibility to innate and adaptive immunotherapy changes during tumour maturationStewart, Trina J., Fernando, Germain J. P., Frazer, Ian H. and Leggatt, Graham R. (2004). Tumour susceptibility to innate and adaptive immunotherapy changes during tumour maturation. Immunology and Cell Biology, 82 (5), 455-461. doi: 10.1111/j.0818-9641.2004.01273.x |
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2004 Journal Article Changes to peptide structure, not concentration, contribute to expansion of the lowest avidity cytotoxic T lymphocytesLeggatt, Graham R., Narayan, Sharmal, Fernando, Germain J. P. and Frazer, Ian H. (2004). Changes to peptide structure, not concentration, contribute to expansion of the lowest avidity cytotoxic T lymphocytes. Journal of Leukocyte Biology, 76 (4), 787-795. doi: 10.1189/jlb.0104026 |
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2004 Journal Article ISCOMATRIX (TM) adjuvant: An adjuvant suitable for use in anticancer vaccinesStewart, Trina J., Drane, Debbie, Malliaros, Jim, Elmer, Heidi, Malcolm, Karen M., Cox, John C., Edwards, Stirling J., Frazer, Ian H. and Fernando, Germain J. P. (2004). ISCOMATRIX (TM) adjuvant: An adjuvant suitable for use in anticancer vaccines. Vaccine, 22 (27-28), 3738-3743. doi: 10.1016/j.vaccine.2004.03.026 |
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2004 Journal Article Despite differences between dendritic cells and Langerhans cells in the mechanism of papillomavirus-like particle antigen uptake, both cells cross-prime T cellsYan, Mengyong, Peng, Judy, Abdul Jabbar, Ibtissam A., Liu, Xiaosong, Filgueira, Luis, Frazer, Ian H. and Thomas, Ranjeny (2004). Despite differences between dendritic cells and Langerhans cells in the mechanism of papillomavirus-like particle antigen uptake, both cells cross-prime T cells. Virology, 324 (2), 297-310. doi: 10.1016/j.virol.2004.03.045 |
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2004 Journal Article Erratum: Cervical cancer control, priorities and new directions (International Journal of Cancer (2003) 108 (329-333))Monsonego, J., Bosch, F. X., Coursaget, P., Cox, J. T., Franco, E., Frazer, I., Sankaranarayanan, R., Schiller, J., Singer, A., Wright Jr., Thomas C., Kinney, W., Meijer, Chris J.L.M., Linder, J. and McGoogan, Euphemia (2004). Erratum: Cervical cancer control, priorities and new directions (International Journal of Cancer (2003) 108 (329-333)). International Journal of Cancer, 108 (6) |
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2004 Journal Article B cell chronic lymphocytic leukaemia cells have reduced capacity to upregulate expression of MHC class I in response to interferon-gammaJuffs, Helen, Fowler, Nina, Saal, Russell, Grimmett, Karen, Beasley, Shannon, O'Sullivan, Brendan, Frazer, Ian H., Gill, Devinder and Thomas, Ranjeny (2004). B cell chronic lymphocytic leukaemia cells have reduced capacity to upregulate expression of MHC class I in response to interferon-gamma. Pathology, 36 (1), 69-76. doi: 10.1080/00313020310001644499 |
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2004 Journal Article Impaired Antigen Presentation and Effectiveness of Combined Active/Passive Immunotherapy for Epithelial TumorsMatsumoto, K., Leggatt, G. R., Zhong, J., Liu, X. S., De Kluyver, R. L., Peters, T., Fernando, G. J. P., Liem, A., Lambert, P. F. and Frazer, I. H. (2004). Impaired Antigen Presentation and Effectiveness of Combined Active/Passive Immunotherapy for Epithelial Tumors. Journal of the National Cancer Institute, 96 (21), 1611-1619. doi: 10.1093/jnci/dhj301 |
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2004 Journal Article Multivariate QTL linkage analysis suggests a QTL for platelet count on chromosome 19qEvans, D. M., Zhu, G., Duffy, D. L., Montgomery, G. W., Frazer, IH and Martin, NG (2004). Multivariate QTL linkage analysis suggests a QTL for platelet count on chromosome 19q. European Journal of Human Genetics, 12 (10), 835-842. doi: 10.1038/sj.ejhg.5201248 |
