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2020

Journal Article

Longer apneas and hypopneas are associated with greater ultra-short-term HRV in obstructive sleep apnea

Hietakoste, Salla, Korkalainen, Henri, Kainulainen, Samu, Sillanmäki, Saara, Nikkonen, Sami, Myllymaa, Sami, Duce, Brett, Töyräs, Juha and Leppänen, Timo (2020). Longer apneas and hypopneas are associated with greater ultra-short-term HRV in obstructive sleep apnea. Scientific Reports, 10 (1) 21556, 21556. doi: 10.1038/s41598-020-77780-x

Longer apneas and hypopneas are associated with greater ultra-short-term HRV in obstructive sleep apnea

2020

Journal Article

Detailed assessment of sleep architecture with deep learning and shorter epoch-to-epoch duration reveals sleep fragmentation of patients with obstructive sleep apnea

Korkalainen, Henri, Leppanen, Timo, Duce, Brett, Kainulainen, Samu, Aakko, Juhani, Leino, Akseli, Kalevo, Laura, Afara, Isaac O, Myllymaa, Sami and Toyras, Juha (2020). Detailed assessment of sleep architecture with deep learning and shorter epoch-to-epoch duration reveals sleep fragmentation of patients with obstructive sleep apnea. IEEE Journal of Biomedical and Health Informatics, PP (7) 9288902, 1-8. doi: 10.1109/JBHI.2020.3043507

Detailed assessment of sleep architecture with deep learning and shorter epoch-to-epoch duration reveals sleep fragmentation of patients with obstructive sleep apnea

2020

Journal Article

Rapid CT-based estimation of articular cartilage biomechanics in the knee joint without cartilage segmentation

Mohammadi, Ali, Myller, Katariina A. H., Tanska, Petri, Hirvasniemi, Jukka, Saarakkala, Simo, Töyräs, Juha, Korhonen, Rami K. and Mononen, Mika E. (2020). Rapid CT-based estimation of articular cartilage biomechanics in the knee joint without cartilage segmentation. Annals of Biomedical Engineering, 48 (12), 2965-2975. doi: 10.1007/s10439-020-02666-y

Rapid CT-based estimation of articular cartilage biomechanics in the knee joint without cartilage segmentation

2020

Journal Article

Tissue optical properties combined with machine learning enables estimation of articular cartilage composition and functional integrity

Kafian-Attari, Iman, Nippolainen, Ervin, Semenov, Dmitry, Hauta-Kasari, Markku, Töyräs, Juha and Afara, Isaac O. (2020). Tissue optical properties combined with machine learning enables estimation of articular cartilage composition and functional integrity. Biomedical Optics Express, 11 (11), 6480-6494. doi: 10.1364/BOE.402929

Tissue optical properties combined with machine learning enables estimation of articular cartilage composition and functional integrity

2020

Journal Article

Tailored synthesis of PEGylated bismuth nanoparticles for x-ray computed tomography and photothermal therapy: one-pot, targeted pyrolysis, and self-promotion

Xu, Wujun, Cui, Pang, Happonen, Emilia, Leppänen, Jukka, Liu, Lizhi, Rantanen, Jimi, Majda, Dorota, Saukko, Annina, Thapa, Rinez, Nissinen, Tuomo, Tynkkynen, Tuulia, Töyräs, Juha, Fan, Li, Liu, Wenchao and Lehto, Vesa-Pekka (2020). Tailored synthesis of PEGylated bismuth nanoparticles for x-ray computed tomography and photothermal therapy: one-pot, targeted pyrolysis, and self-promotion. ACS Applied Materials and Interfaces, 12 (42), 47233-47244. doi: 10.1021/acsami.0c12499

Tailored synthesis of PEGylated bismuth nanoparticles for x-ray computed tomography and photothermal therapy: one-pot, targeted pyrolysis, and self-promotion

2020

Journal Article

Increased nocturnal arterial pulsation frequencies of obstructive sleep apnoea patients is associated with an increased number of lapses in a psychomotor vigilance task

Kainulainen, Samu, Duce, Brett, Korkalainen, Henri, Leino, Akseli, Huttunen, Riku, Kalevo, Laura, Arnardottir, Erna S, Kulkas, Antti, Myllymaa, Sami, Töyräs, Juha and Leppänen, Timo (2020). Increased nocturnal arterial pulsation frequencies of obstructive sleep apnoea patients is associated with an increased number of lapses in a psychomotor vigilance task. ERJ Open Research, 6 (4) 00277-2020, 1-13. doi: 10.1183/23120541.00277-2020

Increased nocturnal arterial pulsation frequencies of obstructive sleep apnoea patients is associated with an increased number of lapses in a psychomotor vigilance task

2020

Journal Article

Power spectral densities of nocturnal pulse oximetry signals differ in OSA patients with and without daytime sleepiness

Kainulainen, Samu, Töyräs, Juha, Oksenberg, Arie, Korkalainen, Henri, Afara, Isaac O., Leino, Akseli, Kalevo, Laura, Nikkonen, Sami, Gadoth, Natan, Kulkas, Antti, Myllymaa, Sami and Leppänen, Timo (2020). Power spectral densities of nocturnal pulse oximetry signals differ in OSA patients with and without daytime sleepiness. Sleep Medicine, 73, 231-237. doi: 10.1016/j.sleep.2020.07.015

Power spectral densities of nocturnal pulse oximetry signals differ in OSA patients with and without daytime sleepiness

2020

Journal Article

Effects of human articular cartilage constituents on simultaneous diffusion of cationic and nonionic contrast agents

Bhattarai, Abhisek, Mäkelä, Janne T. A., Pouran, Behdad, Kröger, Heikki, Weinans, Harrie, Grinstaff, Mark W., Töyräs, Juha and Turunen, Mikael J. (2020). Effects of human articular cartilage constituents on simultaneous diffusion of cationic and nonionic contrast agents. Journal of Orthopaedic Research, 39 (4) jor.24824, 771-779. doi: 10.1002/jor.24824

Effects of human articular cartilage constituents on simultaneous diffusion of cationic and nonionic contrast agents

2020

Journal Article

Quantification of myocardial blood flow by machine learning analysis of modified dual bolus MRI examination

Husso, Minna, Afara, Isaac O., Nissi, Mikko J., Kuivanen, Antti, Halonen, Paavo, Tarkia, Miikka, Teuho, Jarmo, Saunavaara, Virva, Vainio, Pauli, Sipola, Petri, Manninen, Hannu, Ylä-Herttuala, Seppo, Knuuti, Juhani and Töyräs, Juha (2020). Quantification of myocardial blood flow by machine learning analysis of modified dual bolus MRI examination. Annals of Biomedical Engineering, 49 (2), 653-662. doi: 10.1007/s10439-020-02591-0

Quantification of myocardial blood flow by machine learning analysis of modified dual bolus MRI examination

2020

Journal Article

Near-infrared spectroscopy for mapping of human meniscus biochemical constituents

Ala-Myllymäki, Juho, Paakkonen, Tommi, Joukainen, Antti, Kröger, Heikki, Lehenkari, Petri, Töyräs, Juha and Afara, Isaac O. (2020). Near-infrared spectroscopy for mapping of human meniscus biochemical constituents. Annals of Biomedical Engineering, 49 (1), 469-476. doi: 10.1007/s10439-020-02578-x

Near-infrared spectroscopy for mapping of human meniscus biochemical constituents

2020

Journal Article

Accurate deep learning-based sleep staging in a clinical population with suspected obstructive sleep apnea

Korkalainen, Henri, Leppanen, Timo, Aakko, Juhani, Nikkonen, Sami, Kainulainen, Samu, Leino, Akseli, Duce, Brett, Afara, Isaac Oluwaseun, Myllymaa, Sami and Toyras, Juha (2020). Accurate deep learning-based sleep staging in a clinical population with suspected obstructive sleep apnea. IEEE Journal of Biomedical and Health Informatics, 24 (7) 8936942, 2073-2081. doi: 10.1109/JBHI.2019.2951346

Accurate deep learning-based sleep staging in a clinical population with suspected obstructive sleep apnea

2020

Journal Article

Comparison of the effect of weight change, simulated computational continuous positive airway pressure treatment and positional therapy on severity of sleep apnea

Kulkas, Antti, Duce, Brett, Töyräs, Juha, Seppä, Juha and Leppänen, Timo (2020). Comparison of the effect of weight change, simulated computational continuous positive airway pressure treatment and positional therapy on severity of sleep apnea. Journal of Sleep Research, 30 (2) e13070, e13070. doi: 10.1111/jsr.13070

Comparison of the effect of weight change, simulated computational continuous positive airway pressure treatment and positional therapy on severity of sleep apnea

2020

Journal Article

Evaluation of articular cartilage with quantitative MRI in an equine model of post-traumatic osteoarthritis

Kajabi, Abdul Wahed, Casula, Victor, Sarin, Jaakko K., Ketola, Juuso H., Nykänen, Olli, te Moller, Nikae C. R., Mancini, Irina A. D., Visser, Jetze, Brommer, Harold, René van Weeren, P., Malda, Jos, Töyräs, Juha, Nieminen, Miika T. and Nissi, Mikko J. (2020). Evaluation of articular cartilage with quantitative MRI in an equine model of post-traumatic osteoarthritis. Journal of Orthopaedic Research, 39 (1) jor.24780, 63-73. doi: 10.1002/jor.24780

Evaluation of articular cartilage with quantitative MRI in an equine model of post-traumatic osteoarthritis

2020

Journal Article

Bright ultrashort echo time SWIFT MRI signal at the osteochondral junction is not located in the calcified cartilage

Nykänen, Olli, Leskinen, Henri P. P., Finnilä, Mikko A. J., Karhula, Sakari S., Turunen, Mikael J., Töyräs, Juha, Saarakkala, Simo and Nissi, Mikko J. (2020). Bright ultrashort echo time SWIFT MRI signal at the osteochondral junction is not located in the calcified cartilage. Journal of Orthopaedic Research, 38 (12) jor.24777, 2649-2656. doi: 10.1002/jor.24777

Bright ultrashort echo time SWIFT MRI signal at the osteochondral junction is not located in the calcified cartilage

2020

Journal Article

Dual contrast in computed tomography allows earlier characterization of articular cartilage over single contrast

Bhattarai, Abhisek, Pouran, Behdad, Mäkelä, Janne T. A., Shaikh, Rubina, Honkanen, Miitu K. M., Prakash, Mithilesh, Kröger, Heikki, Grinstaff, Mark W., Weinans, Harrie, Jurvelin, Jukka S. and Töyräs, Juha (2020). Dual contrast in computed tomography allows earlier characterization of articular cartilage over single contrast. Journal of Orthopaedic Research, 38 (10) jor.24774, 2230-2238. doi: 10.1002/jor.24774

Dual contrast in computed tomography allows earlier characterization of articular cartilage over single contrast

2020

Journal Article

Estimating daytime sleepiness with previous night EEG, EOG and EMG spectrograms in patients with suspected sleep apnea using a convolutional neural network

Nikkonen, Sami, Korkalainen, Henri, Kainulainen, Samu, Myllymaa, Sami, Leino, Akseli, Kalevo, Laura, Oksenberg, Arie, Leppänen, Timo and Töyräs, Juha (2020). Estimating daytime sleepiness with previous night EEG, EOG and EMG spectrograms in patients with suspected sleep apnea using a convolutional neural network. Sleep, 43 (12) zsaa106. doi: 10.1093/sleep/zsaa106

Estimating daytime sleepiness with previous night EEG, EOG and EMG spectrograms in patients with suspected sleep apnea using a convolutional neural network

2020

Journal Article

Deep learning enables sleep staging from photoplethysmogram for patients with suspected sleep apnea

Korkalainen, Henri, Aakko, Juhani, Duce, Brett, Kainulainen, Samu, Leino, Akseli, Nikkonen, Sami, Afara, Isaac O., Myllymaa, Sami, Töyräs, Juha and Leppänen, Timo (2020). Deep learning enables sleep staging from photoplethysmogram for patients with suspected sleep apnea. Sleep, 43 (11) zsaa098. doi: 10.1093/sleep/zsaa098

Deep learning enables sleep staging from photoplethysmogram for patients with suspected sleep apnea

2020

Journal Article

Clinical contrast-enhanced computed tomography with semiautomatic segmentation provides feasible input for computational models of the knee joint

Myller, Katariina Anna Henriikka, Korhonen, Rami, Töyräs, Juha, Tanska, Petri, Väänänen, Sami, Jurvelin, Jukka S, Saarakkala, Simo and Mononen, Mika E (2020). Clinical contrast-enhanced computed tomography with semiautomatic segmentation provides feasible input for computational models of the knee joint. Journal of Biomechanical Engineering, 142 (5) 051001. doi: 10.1115/1.4045279

Clinical contrast-enhanced computed tomography with semiautomatic segmentation provides feasible input for computational models of the knee joint

2020

Journal Article

Open-source python module for automated preprocessing of near infrared spectroscopic data

Torniainen, Jari, Afara, Isaac O., Prakash, Mithilesh, Sarin, Jaakko K., Stenroth, Lauri and Töyräs, Juha (2020). Open-source python module for automated preprocessing of near infrared spectroscopic data. Analytica Chimica Acta, 1108, 1-9. doi: 10.1016/j.aca.2020.02.030

Open-source python module for automated preprocessing of near infrared spectroscopic data

2020

Journal Article

Polysomnographic characteristics of severe obstructive sleep apnea vary significantly between hypertensive and normotensive patients of both genders

Leppanen, T., Kulkas, A., Toyras, J., Myllymaa, S., Gadoth, N. and Oksenberg, A. (2020). Polysomnographic characteristics of severe obstructive sleep apnea vary significantly between hypertensive and normotensive patients of both genders. Sleep and Breathing, 25 (1), 105-116. doi: 10.1007/s11325-020-02047-8

Polysomnographic characteristics of severe obstructive sleep apnea vary significantly between hypertensive and normotensive patients of both genders