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2020

Journal Article

Near infrared spectroscopy enables differentiation of mechanically and enzymatically induced cartilage injuries

Nippolainen, Ervin, Shaikh, Rubina, Virtanen, Vesa, Rieppo, Lassi, Saarakkala, Simo, Töyräs, Juha and Afara, Isaac O. (2020). Near infrared spectroscopy enables differentiation of mechanically and enzymatically induced cartilage injuries. Annals of Biomedical Engineering, 48 (9), 2343-2353. doi: 10.1007/s10439-020-02506-z

Near infrared spectroscopy enables differentiation of mechanically and enzymatically induced cartilage injuries

2019

Conference Publication

Artificial neural network analysis of blood oxygen saturation signal enables accurate automatic screening of sleep apnea

Nikkonen, S., Afara, I., Myllymaa, S., Toyras, J. and Leppanen, T. (2019). Artificial neural network analysis of blood oxygen saturation signal enables accurate automatic screening of sleep apnea. World Sleep Congress, Vancouver, Canada, 20-25 September 2019. Amsterdam, Netherlands: Elsevier . doi: 10.1016/j.sleep.2019.11.624

Artificial neural network analysis of blood oxygen saturation signal enables accurate automatic screening of sleep apnea

2019

Conference Publication

Deep learning enables accurate sleep staging based on a single frontal EEG channel

Korkalainen, H., Aakko, J., Nikkonen, S., Kainulainen, S., Leino, A., Duce, B., Afara, I. O., Myllymaa, S., Toyras, J. and Leppanen, T. (2019). Deep learning enables accurate sleep staging based on a single frontal EEG channel. 15th World Sleep Congress, World Sleep 2019, Vancouver, Canada, 20-25 September, 2019 . Amsterdam, Netherlands: Elsevier BV.

Deep learning enables accurate sleep staging based on a single frontal EEG channel

2019

Journal Article

Mortality-risk-based apnea–hypopnea index thresholds for diagnostics of obstructive sleep apnea

Korkalainen, Henri, Töyräs, Juha, Nikkonen, Sami and Leppänen, Timo (2019). Mortality-risk-based apnea–hypopnea index thresholds for diagnostics of obstructive sleep apnea. Journal of Sleep Research, 28 (6) e12855, e12855. doi: 10.1111/jsr.12855

Mortality-risk-based apnea–hypopnea index thresholds for diagnostics of obstructive sleep apnea

2019

Journal Article

Does magnetic resonance imaging provide superior reliability for achilles and patellar tendon cross-sectional area measurements compared with ultrasound imaging?

Stenroth, Lauri, Sefa, Sandra, Arokoski, Jari and Töyräs, Juha (2019). Does magnetic resonance imaging provide superior reliability for achilles and patellar tendon cross-sectional area measurements compared with ultrasound imaging?. Ultrasound in Medicine and Biology, 45 (12), 3186-3198. doi: 10.1016/j.ultrasmedbio.2019.08.001

Does magnetic resonance imaging provide superior reliability for achilles and patellar tendon cross-sectional area measurements compared with ultrasound imaging?

2019

Conference Publication

Differentiating Sleepy and non-sleepy obstructive sleep apnea patients using nocturnal pulse oximetry and deep learning

Kainulainen, S., Toyras, J., Oksenberg, A., Korkalainen, H., Afara, I., Leino, A., Kalevo, L., Nikkonen, S., Gadoth, N., Kulkas, A., Myllymaa, S. and Leppanen, T. (2019). Differentiating Sleepy and non-sleepy obstructive sleep apnea patients using nocturnal pulse oximetry and deep learning. World Sleep Congress, Vancouver, Canada, 20-25 September 2019. Amsterdam, Netherlands: Elsevier . doi: 10.1016/j.sleep.2019.11.508

Differentiating Sleepy and non-sleepy obstructive sleep apnea patients using nocturnal pulse oximetry and deep learning

2019

Journal Article

Contrast enhanced computed tomography for real-time quantification of glycosaminoglycans in cartilage tissue engineered constructs

Garcia, João P., Longoni, Alessia, Gawlitta, Debby, J.W.P. Rosenberg, Antoine, Grinstaff, Mark W., Töyräs, Juha, Weinans, Harrie, Creemers, Laura B. and Pouran, Behdad (2019). Contrast enhanced computed tomography for real-time quantification of glycosaminoglycans in cartilage tissue engineered constructs. Acta Biomaterialia, 100, 202-212. doi: 10.1016/j.actbio.2019.09.014

Contrast enhanced computed tomography for real-time quantification of glycosaminoglycans in cartilage tissue engineered constructs

2019

Journal Article

Triple contrast CT method enables simultaneous evaluation of articular cartilage composition and segmentation

Honkanen, Miitu K. M., Saukko, Annina E. A., Turunen, Mikael J., Xu, Wujun, Lovric, Goran, Honkanen, Juuso T. J., Grinstaff, Mark W., Lehto, Vesa-Pekka and Töyräs, Juha (2019). Triple contrast CT method enables simultaneous evaluation of articular cartilage composition and segmentation. Annals of Biomedical Engineering, 48 (2), 556-567. doi: 10.1007/s10439-019-02362-6

Triple contrast CT method enables simultaneous evaluation of articular cartilage composition and segmentation

2019

Journal Article

Effects of body mass on microstructural features of the osteochondral unit: A comparative analysis of 37 mammalian species

Mancini, I. A.D., Rieppo, L., Pouran, B., Afara, I. O., Braganca, F.M. Serra, van Rijen, M. H.P., Kik, M., Weinans, H., Toyras, J., van Weeren, P. R. and Malda, J. (2019). Effects of body mass on microstructural features of the osteochondral unit: A comparative analysis of 37 mammalian species. Bone, 127, 664-673. doi: 10.1016/j.bone.2019.07.001

Effects of body mass on microstructural features of the osteochondral unit: A comparative analysis of 37 mammalian species

2019

Journal Article

Synchrotron MicroCT reveals the potential of the dual contrast technique for quantitative assessment of human articular cartilage composition

Honkanen, Miitu K. M., Saukko, Annina E. A., Turunen, Mikael J., Shaikh, Rubina, Prakash, Mithilesh, Lovric, Goran, Joukainen, Antti, Kroger, Heikki, Grinstaff, Mark W. and Toyras, Juha (2019). Synchrotron MicroCT reveals the potential of the dual contrast technique for quantitative assessment of human articular cartilage composition. Journal of Orthopaedic Research, 38 (3) jor.24479, 563-573. doi: 10.1002/jor.24479

Synchrotron MicroCT reveals the potential of the dual contrast technique for quantitative assessment of human articular cartilage composition

2019

Journal Article

Artificial neural network analysis of the oxygen saturation signal enables accurate diagnostics of sleep apnea

Nikkonen, Sami, Afara, Isaac O., Leppänen, Timo and Töyräs, Juha (2019). Artificial neural network analysis of the oxygen saturation signal enables accurate diagnostics of sleep apnea. Scientific Reports, 9 (1) 13200, 13200. doi: 10.1038/s41598-019-49330-7

Artificial neural network analysis of the oxygen saturation signal enables accurate diagnostics of sleep apnea

2019

Journal Article

Dataset on equine cartilage near infrared spectra, composition, and functional properties

Sarin, Jaakko K., Torniainen, Jari, Prakash, Mithilesh, Rieppo, Lassi, Afara, Isaac O. and Toyras, Juha (2019). Dataset on equine cartilage near infrared spectra, composition, and functional properties. Scientific Data, 6 (1) 164, 164. doi: 10.1038/s41597-019-0170y

Dataset on equine cartilage near infrared spectra, composition, and functional properties

2019

Journal Article

Severity of desaturations reflects OSA-related daytime sleepiness better than AHI

Kainulainen, Samu, Töyräs, Juha, Oksenberg, Arie, Korkalainen, Henri, Sefa, Sandra, Kulkas, Antti and Leppänen, Timo (2019). Severity of desaturations reflects OSA-related daytime sleepiness better than AHI. Journal of Clinical Sleep Medicine, 15 (8), 1135-1142. doi: 10.5664/jcsm.7806

Severity of desaturations reflects OSA-related daytime sleepiness better than AHI

2019

Journal Article

Polysomnographic scoring of sleep bruxism events is accurate even in the absence of video recording but unreliable with EMG-only setups

Miettinen, Tomi, Myllymaa, Katja, Muraja-Murro, Anu, Westeren-Punnonen, Susanna, Hukkanen, Taina, Töyräs, Juha, Lappalainen, Reijo, Mervaala, Esa, Sipilä, Kirsi and Myllymaa, Sami (2019). Polysomnographic scoring of sleep bruxism events is accurate even in the absence of video recording but unreliable with EMG-only setups. Sleep and Breathing, 24 (3), 893-904. doi: 10.1007/s11325-019-01915-2

Polysomnographic scoring of sleep bruxism events is accurate even in the absence of video recording but unreliable with EMG-only setups

2019

Journal Article

Identification of locations susceptible to osteoarthritis in patients with anterior cruciate ligament reconstruction: Combining knee joint computational modelling with follow-up T1ρ and T2 imaging

Bolcos, Paul O., Mononen, Mika E., Tanaka, Matthew S., Yang, Mingrui, Suomalainen, Juha-Sampo, Nissi, Mikko J., Töyräs, Juha, Ma, Benjamin, Li, Xiaojuan and Korhonen, Rami K. (2019). Identification of locations susceptible to osteoarthritis in patients with anterior cruciate ligament reconstruction: Combining knee joint computational modelling with follow-up T1ρ and T2 imaging. Clinical Biomechanics, 79 104844, 104844. doi: 10.1016/j.clinbiomech.2019.08.004

Identification of locations susceptible to osteoarthritis in patients with anterior cruciate ligament reconstruction: Combining knee joint computational modelling with follow-up T1ρ and T2 imaging

2019

Journal Article

Near-infrared spectroscopy enables quantitative evaluation of human cartilage biomechanical properties during arthroscopy

Prakash, M., Joukainen, A., Torniainen, J., Honkanen, M. K.M., Rieppo, L., Afara, I. O., Kröger, H., Töyräs, J. and Sarin, J. K. (2019). Near-infrared spectroscopy enables quantitative evaluation of human cartilage biomechanical properties during arthroscopy. Osteoarthritis and Cartilage, 27 (8), 1235-1243. doi: 10.1016/j.joca.2019.04.008

Near-infrared spectroscopy enables quantitative evaluation of human cartilage biomechanical properties during arthroscopy

2019

Journal Article

Arthroscopic determination of cartilage proteoglycan content and collagen network structure with near-infrared spectroscopy

Sarin, Jaakko K., Nykänen, Olli, Tiitu, Virpi, Mancini, Irina A. D., Brommer, Harold, Visser, Jetze, Malda, Jos, van Weeren, P. René, Afara, Isaac O. and Töyräs, Juha (2019). Arthroscopic determination of cartilage proteoglycan content and collagen network structure with near-infrared spectroscopy. Annals of Biomedical Engineering, 47 (8), 1815-1826. doi: 10.1007/s10439-019-02280-7

Arthroscopic determination of cartilage proteoglycan content and collagen network structure with near-infrared spectroscopy

2019

Journal Article

Quantification of porcine myocardial perfusion with modified dual bolus MRI - a prospective study with a PET reference

Husso, Minna, Nissi, Mikko J., Kuivanen, Antti, Halonen, Paavo, Tarkia, Miikka, Teuho, Jarmo, Saunavaara, Virva, Vainio, Pauli, Sipola, Petri, Manninen, Hannu, Ylä-Herttuala, Seppo, Knuuti, Juhani and Toÿräs, Juha (2019). Quantification of porcine myocardial perfusion with modified dual bolus MRI - a prospective study with a PET reference. BMC Medical Imaging, 19 (1) 58, 58. doi: 10.1186/s12880-019-0359-8

Quantification of porcine myocardial perfusion with modified dual bolus MRI - a prospective study with a PET reference

2019

Journal Article

Prevalence and characteristics of positional obstructive sleep apnea (POSA) in patients with severe OSA

Oksenberg, Arie, Gadoth, Natan, Töyräs, Juha and Leppänen, Timo (2019). Prevalence and characteristics of positional obstructive sleep apnea (POSA) in patients with severe OSA. Sleep and Breathing, 24 (2), 551-559. doi: 10.1007/s11325-019-01897-1

Prevalence and characteristics of positional obstructive sleep apnea (POSA) in patients with severe OSA

2019

Journal Article

Intra-night variation in apnea-hypopnea index affects diagnostics and prognostics of obstructive sleep apnea

Nikkonen, Sami, Töyräs, Juha, Mervaala, Esa, Myllymaa, Sami, Terrill, Philip and Leppänen, Timo (2019). Intra-night variation in apnea-hypopnea index affects diagnostics and prognostics of obstructive sleep apnea. Sleep and Breathing, 24 (1), 379-386. doi: 10.1007/s11325-019-01885-5

Intra-night variation in apnea-hypopnea index affects diagnostics and prognostics of obstructive sleep apnea