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2006 Journal Article Altered phosphorylation of cytoskeletal proteins in mutant protein phosphatase 2A transgenic miceSchild, Andreas, Ittner, Lars M. and Gotz, Juergen (2006). Altered phosphorylation of cytoskeletal proteins in mutant protein phosphatase 2A transgenic mice. Biochemical and Biophysical Research Communications, 343 (4), 1171-1178. doi: 10.1016/j.bbrc.2006.03.066 |
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2006 Journal Article Impaired development of the Harderian gland in mutant protein phosphatase 2A transgenic miceSchild, Andreas, Isenmann, Stefan, Tanimoto, Naoyuki, Tonagel, Felix, Seeliger, Mathias W., Ittner, Lars M., Kretz, Alexandra, Ogris, Egon and Gotz, Juergen (2006). Impaired development of the Harderian gland in mutant protein phosphatase 2A transgenic mice. Mechanisms of Development, 123 (5), 362-371. doi: 10.1016/j.mod.2006.03.003 |
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2006 Journal Article Active immunization trial in Aβ42-injected P301L tau transgenic miceKulic, Luka, Kurosinski, Pascal, Chen, Feng, Tracy, Jay, Mohajeri, M. Hasan, Li, Hong, Nitsch, Roger M. and Gotz, Juergen (2006). Active immunization trial in Aβ42-injected P301L tau transgenic mice. Neurobiology of Disease, 22 (1), 50-56. doi: 10.1016/j.nbd.2005.10.002 |
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2006 Journal Article Enhanced vascular responses to adrenomedullin in mice overexpressing receptor-activity-modifying protein 2Tam, CW, Husmann, K, Clark, NC, Clark, JE, Lazar, Z, Ittner, LM, Gotz, J, Douglas, G, Grant, AD, Sugden, D, Poston, L, Poston, R, McFadzean, I, Marber, MS, Fischer, JA, Born, W and Brain, SD (2006). Enhanced vascular responses to adrenomedullin in mice overexpressing receptor-activity-modifying protein 2. Circulation Research, 98 (2), 262-270. doi: 10.1161/01.RES.0000200737.638.65.58 |
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2006 Journal Article P70 S6 kinase mediates tau phosphorylation and synthesisPei, Jin-Jing, An, Wen-Lin, Zhou, Xin-Wen, Nishimura, Takeshi, Norberg, Jan, Benedikz, Eirikur, Gotz, Juergen and Winblad, Bengt (2006). P70 S6 kinase mediates tau phosphorylation and synthesis. FEBS Letters, 580 (1), 107-114. doi: 10.1016/j.febslet.2005.11.059 |
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2006 Conference Publication Transgenic animal models of Alzheimer's diseaseGotz, J. (2006). Transgenic animal models of Alzheimer's disease. 19th Congress of the European-College-of-Neuropsychopharmacology, Paris France, Sep 16-20, 2006. LIPPINCOTT WILLIAMS & WILKINS. doi: 10.1016/S0924-977X(06)70110-9 |
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2005 Journal Article Different tau epitopes define Aβ42-mediated tau insolubilityPennanen, Luis and Gotz, Juergen (2005). Different tau epitopes define Aβ42-mediated tau insolubility. Biochemical and Biophysical Research Communications, 337 (4), 1097-1101. doi: 10.1016/j.bbrc.2005.09.168 |
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2005 Journal Article Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic miceDavid, Della C., Hauptmann, Susanne, Scherping, Isabel, Schuessel, Katrin, Keil, Uta, Rizzu, Patrizia, Ravid, Rivka, Drose, Stefan, Brandt, Ulrich, Muller, Walter E., Eckert, Anne and Gotz, Juergen (2005). Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice. Journal of Biological Chemistry, 280 (25), 23802-23814. doi: 10.1074/jbc.M500356200 |
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2005 Journal Article Functional genomics meets neurodegenerative disorders: part II: application and data integrationHoerndli, Frederic, David, Della C. and Gotz, Juergen (2005). Functional genomics meets neurodegenerative disorders: part II: application and data integration. Progress in Neurobiology, 76 (3), 169-188. doi: 10.1016/j.pneurobio.2005.07.002 |
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2005 Journal Article Functional genomics meets neurodegenerative disorders: part I: transcriptomic and proteomic technologyDavid, Della C., Hoerndli, Frederic and Gotz, Juergen (2005). Functional genomics meets neurodegenerative disorders: part I: transcriptomic and proteomic technology. Progress in Neurobiology, 76 (3), 153-168. doi: 10.1016/j.pneurobio.2005.07.001 |
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2005 Journal Article Role of the protein tau in Alzheimer's diseaseGötz, Jürgen, Ittner, Lars M. and David, Della C. (2005). Role of the protein tau in Alzheimer's disease. Drug Discovery Today: Disease Mechanisms, 2 (4), 395-400. doi: 10.1016/j.ddmec.2005.11.008 |
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2004 Journal Article Reference genes identified in SH-SY5Y cells using custom-made gene arrays with validation by quantitative polymerase chain reactionHoerndli, Frédéric J., Toigo, Marco, Schild, Andreas, Gotz, Jürgen and Day, Philip J. (2004). Reference genes identified in SH-SY5Y cells using custom-made gene arrays with validation by quantitative polymerase chain reaction. Analytical Biochemistry, 335 (1), 30-41. doi: 10.1016/j.ab.2004.08.028 |
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2004 Journal Article Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: insight from transgenic mouse and tissue-culture modelsGotz, Juergen, Schild, Andreas, Hoerndli, Fred and Pennanen, Luis (2004). Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: insight from transgenic mouse and tissue-culture models. International Journal of Developmental Neuroscience, 22 (7), 453-465. doi: 10.1016/j.ijdevneu.2004.07.013 |
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2004 Conference Publication Amyloid-induced neurofibrillary tangle formation addressed in vivo and in vitroPennanen, L, David, D, Hoerndli, F, Kurosinski, P, Chen, F, Schild, A, Ferrari, A, Nitsch, RM and Gotz, J (2004). Amyloid-induced neurofibrillary tangle formation addressed in vivo and in vitro. 9th International Conference on Alzheimers Disease and Related Disorders, Philadelphia Pa, Jul 17-22, 2004. ELSEVIER SCIENCE INC. doi: 10.1016/S0197-4580(04)80857-1 |
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2004 Journal Article Transgenic animal models of Alzheimer's disease and related disorders: Histopathology, behavior and therapyGotz, J, Streffer, JR, David, D, Schild, A, Hoerndli, F, Pennanen, L, Kurosinski, P and Chen, F (2004). Transgenic animal models of Alzheimer's disease and related disorders: Histopathology, behavior and therapy. Molecular Psychiatry, 9 (7), 664-683. doi: 10.1038/sj.mp.4001508 |
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2004 Journal Article Role for glyoxalase I in Alzheimer's diseaseChen, Feng, Wollmer, M. Axel, Hoerndli, Frederic, Munch, Gerald, Kuhla, Bjorn, Rogaev, Evgeny I., Tsolaki, Magdalini, Papassotiropoulos, Andreas and Gotz, Juergen (2004). Role for glyoxalase I in Alzheimer's disease. National Academy of Sciences. Proceedings, 101 (20), 7687-7692. doi: 10.1073/pnas.0402338101 |
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2004 Journal Article Accelerated extinction of conditioned taste aversion in P301L tau transgenic micePennanen, Luis, Welzl, Hans, D'Adamo, Patrizia, Nitsch, Roger M. and Gotz, Juergen (2004). Accelerated extinction of conditioned taste aversion in P301L tau transgenic mice. Neurobiology of Disease, 15 (3), 500-509. doi: 10.1016/j.nbd.2003.11.020 |
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2004 Journal Article Genomic organisation, chromosomal localisation tissue distribution and developmental regulation of the PR61/B′ regulatory subunits of protein phosphatase 2A in miceMartens, Ellen, Stevens, Ilse, Janssens, Veerle, Vermeesch, Joris, Gotz, Juergen, Goris, Jozef and Van Hoof , Christine Van (2004). Genomic organisation, chromosomal localisation tissue distribution and developmental regulation of the PR61/B′ regulatory subunits of protein phosphatase 2A in mice. Journal of Molecular Biology, 336 (4), 971-986. doi: 10.1016/j.jmb.2003.12.047 |
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2004 Journal Article Posttranslational modifications of tau - Role in human tauopathies and modeling in transgenic animalsChen F., David D., Ferrari A. and Gotz J. (2004). Posttranslational modifications of tau - Role in human tauopathies and modeling in transgenic animals. Current Drug Targets, 5 (6), 503-515. doi: 10.2174/1389450043345236 |
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2004 Journal Article Transgenic Mice Expressing the Nucleoprotein of Borna Disease Virus in either Neurons or Astrocytes: Decreased Susceptibility to Homotypic Infection and DiseaseRauer, Mathias, Gotz, Jurgen, Schuppli, Daniel, Staeheli, Peter and Hausmann, Jurgen (2004). Transgenic Mice Expressing the Nucleoprotein of Borna Disease Virus in either Neurons or Astrocytes: Decreased Susceptibility to Homotypic Infection and Disease. Journal of Virology, 78 (7), 3621-3632. doi: 10.1128/JVI.78.7.3621-3632.2004 |
